BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0083.p (263 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv1928c [IQR] COG1028 Dehydrogenases with different specificitie... 160 3e-39 PA1828 [IQR] COG1028 Dehydrogenases with different specificities... 159 4e-39 CC1808 [IQR] COG1028 Dehydrogenases with different specificities... 158 1e-38 alr4456 [IQR] COG1028 Dehydrogenases with different specificitie... 156 4e-38 mlr3785 [IQR] COG1028 Dehydrogenases with different specificitie... 154 2e-37 >Rv1928c [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mtu Mycobacterium tuberculosis H37Rv Length = 255 Score = 160 bits (405), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 99/255 (38%), Positives = 147/255 (57%), Gaps = 13/255 (5%) Query: 14 FRMDGRTALITGASKGLGEAMAEALAEQGAKVVLVARTTSELETVAARIRSQGGQAEVRT 73 F + G+ ALITGAS G+G+ +A A E GA+V + AR LE +A I + GG+ Sbjct: 7 FDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDALEKLADEIGTSGGKVVPVC 66 Query: 74 CDVTDRKAIRAVI----ASLEELDILINNAGSNIPEPIDVVTDEHLDYLQDLNTTAYFVV 129 CDV+ + + +++ A L +DI + NAG P+ + E LQ+ N T F+ Sbjct: 67 CDVSQHQQVTSMLDQVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLT 126 Query: 130 AQAAVKKMKEHPDRKNRGASIINIASQMGHIGSESRTV--YCMTKHAVVGLTRAMAVELA 187 AQAA K M ++ +G IIN AS GHI + + V YC +K AV+ LT+AMAVELA Sbjct: 127 AQAAAKAMV----KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELA 182 Query: 188 ATGIRVNSIGPTFIDTPLVRRVVDTPEKYNTLVSRIPMGHMGQVQDIAAAAVYLASSASG 247 IRVNS+ P +I T LV + + +IP+G +G+ +++A +YLAS AS Sbjct: 183 PHKIRVNSVSPGYILTELVEPYTEYQPLWE---PKIPLGRLGRPEELAGLYLYLASEASS 239 Query: 248 MVTGAGLLVDGGWTA 262 +TG+ +++DGG+T Sbjct: 240 YMTGSDIVIDGGYTC 254 >PA1828 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 255 Score = 159 bits (403), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 96/256 (37%), Positives = 145/256 (56%), Gaps = 14/256 (5%) Query: 12 HRFRMDGRTALITGASKGLGEAMAEALAEQGAKVVLVARTTSELETVAARIRSQGGQAEV 71 H F +DG+ A ++GAS+G+GEA+A+ LA+QGA V++ +R + VA I ++GG+A Sbjct: 5 HLFDLDGKIAFVSGASRGIGEAIAKLLAQQGAHVIVSSRKIDGCQAVADAITAEGGKATA 64 Query: 72 RTCDVTDRKAIRAVIASLEE----LDILINNAGSNIPEPIDVVTDEHLDYLQ---DLNTT 124 C + + + I+ V A + E LDIL+NNA +N P+ +V+ + L Q D+N Sbjct: 65 IACHIGEMEQIQNVFAQIREQFGRLDILVNNAATN-PQFCNVL-ETDLGAFQKTVDVNIR 122 Query: 125 AYFVVAQAAVKKMKEHPDRKNRGASIINIASQMGHIGSESRTVYCMTKHAVVGLTRAMAV 184 Y+ ++ K MKEH G SIIN+AS G E + +Y +TK AV+ +T+ A Sbjct: 123 GYYFMSIEGGKLMKEHG-----GGSIINVASINGVSPGEFQGIYSVTKAAVISMTKVFAK 177 Query: 185 ELAATGIRVNSIGPTFIDTPLVRRVVDTPEKYNTLVSRIPMGHMGQVQDIAAAAVYLASS 244 E A GIR N++ P DT +V N + RIP+ + + ++A A +YLAS Sbjct: 178 ECAQFGIRCNALLPGLTDTKFASALVKNDAIRNLALQRIPLKRVAEPSEMAGAVLYLASE 237 Query: 245 ASGMVTGAGLLVDGGW 260 AS TG L VDGG+ Sbjct: 238 ASSYTTGVALNVDGGF 253 >CC1808 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 252 Score = 158 bits (400), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 98/249 (39%), Positives = 138/249 (55%), Gaps = 10/249 (4%) Query: 15 RMDGRTALITGASKGLGEAMAEALAEQGAKVVLVARTTSELETVAARIRSQGGQAEVRTC 74 R++GR A +TGAS+GLG A A LA +GA V L+ + A I + GG+A C Sbjct: 4 RLEGRVAAVTGASRGLGRATAALLAAEGAMVALLDLKAHWAQAAADEIIAAGGKAVGLGC 63 Query: 75 DVTDRKAIRAVIASLEE----LDILINNAGSNIPEPIDVVTDEHLDYLQDLNTTAYFVVA 130 DV+DR+A+ A + ++ + D+L+NNA N+ EP+ + E LD + + + Sbjct: 64 DVSDREALTATLGAVNDAHGRFDVLVNNAMWNVYEPLAAIRPESLDRMVSVGFSGVIWGM 123 Query: 131 QAAVKKMKEHPDRKNRGASIINIASQMGHIGSESRTVYCMTKHAVVGLTRAMAVELAATG 190 QAA M + G SI+NIAS +G + YC K V G+TRA A EL A Sbjct: 124 QAAAPLMA-----ASGGGSIVNIASVSAQLGIPNGIAYCGVKAGVAGMTRAAAAELGAMN 178 Query: 191 IRVNSIGPTFIDTPLVRRVVDTPEKYNTLVSRIPMGHMGQVQDIAAAAVYLASSASGMVT 250 IRVN++ P+ +DT VRRVV + E+ + + P+G +G +DIA A YLA S VT Sbjct: 179 IRVNAVAPSTVDTEGVRRVV-SEERIAMRIGQTPLGRLGTTEDIAKAVRYLACDDSDFVT 237 Query: 251 GAGLLVDGG 259 G L VDGG Sbjct: 238 GQMLTVDGG 246 >alr4456 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Nos Nostoc sp. PCC 7120 Length = 267 Score = 156 bits (395), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 97/266 (36%), Positives = 147/266 (55%), Gaps = 10/266 (3%) Query: 1 VTTSTFTNGIAHRFRMDGRTALITGASKGLGEAMAEALAEQGAKVVLVARTTSELETVAA 60 VT F I R+ + GR ALITGA+KG+G A+A+ GA+VV+VAR +E Sbjct: 5 VTPPAFGEKIRERWTLAGRKALITGATKGIGLAIAQEFLALGAEVVIVARNAEAIEQQMK 64 Query: 61 RIRSQGG----QAEVRTCDVTDRKAIRAVIASLEELDILINNAGSNIPEPIDVVTDEHLD 116 S G A+V T + + + V + ELDIL+NN G+NI + T+E Sbjct: 65 AWHSAGKVHGVAADVSTSE-GRQMMLDYVSKTFGELDILVNNVGTNIRKKATDYTEEEFA 123 Query: 117 YLQDLNTTAYFVVAQAAVKKMKEHPDRKNRGASIINIASQMGHIGSESRTVYCMTKHAVV 176 + +N T+ F +++ +K ++ +SI+NI S G I + Y MTK A+V Sbjct: 124 AIFQINLTSIFELSRLFYPLLK-----TSKNSSIVNIGSVAGLISVRTGAPYGMTKAALV 178 Query: 177 GLTRAMAVELAATGIRVNSIGPTFIDTPLVRRVVDTPEKYNTLVSRIPMGHMGQVQDIAA 236 LTR++AVE A GIRVN+I P FI TPL +++ PE + ++SR PM +GQ +++A+ Sbjct: 179 QLTRSLAVEWADDGIRVNAIAPWFIQTPLTEPLLNNPETLSAVLSRTPMKRVGQPEEVAS 238 Query: 237 AAVYLASSASGMVTGAGLLVDGGWTA 262 +L + +TG + VDGG+ A Sbjct: 239 LTAFLCMPTASYITGQCIAVDGGFLA 264 >mlr3785 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 251 Score = 154 bits (389), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 98/256 (38%), Positives = 138/256 (53%), Gaps = 13/256 (5%) Query: 11 AHRFRMDGRTALITGASKGLGEAMAEALAEQGAKVVLVARTTSELETVAARIRSQGGQAE 70 A+ F + GR AL+TG+S+G+G A+A+ LA+ GA V+L R T++L AA+I A+ Sbjct: 3 ANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPG----AQ 58 Query: 71 VRTCDVTDRKAIRAVIASLE----ELDILINNAGSNIPEPIDVVTDEHLDYLQDLNTTAY 126 D T+ A+R+ I + E +DIL+NNAG P++ + + L N + Sbjct: 59 TLAFDATEHDAVRSAIDNFELSGGPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASV 118 Query: 127 FVVAQAAVKKMKEHPDRKNRGASIINIASQMGHIGSESRTVYCMTKHAVVGLTRAMAVEL 186 F V QA + M R+ RG IINIAS + Y TK AV LT+ MA + Sbjct: 119 FHVGQAVARHMI----RRGRG-KIINIASVQTALARPGIAPYTATKGAVGNLTKGMATDW 173 Query: 187 AATGIRVNSIGPTFIDTPLVRRVVDTPEKYNTLVSRIPMGHMGQVQDIAAAAVYLASSAS 246 A G++ N+I P + DTPL +V P L R P G G+V+++ A V+LAS AS Sbjct: 174 AKHGLQCNAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDAS 233 Query: 247 GMVTGAGLLVDGGWTA 262 V G L VDGG TA Sbjct: 234 SFVNGHILYVDGGITA 249