BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0068.p (361 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 216 5e-56 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 203 4e-52 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 192 1e-48 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 176 8e-44 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 176 1e-43 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 216 bits (551), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 121/320 (37%), Positives = 182/320 (56%), Gaps = 5/320 (1%) Query: 15 MEERPLGWYQWRILFICFICLMVDGFDAQALAYVAPVMRQELGISTSELGLIFSSSLIGM 74 ++ + +QW ++ +CF + +DGFD + ++AP + Q+ I + LG +FS+ L G+ Sbjct: 14 LDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTVFSAGLAGL 73 Query: 75 LFGAFLLSPLADRFGRRPMMIAAMGICSVAMLLAPATASFSSLVAIRFVTGLGLGVILPN 134 + GA + PLADR GR+ ++ +G +A +L+ S +LVA+RF+TGLGLG +PN Sbjct: 74 MVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGLGLGGAMPN 133 Query: 135 ALALVSEFSPERRRSILVMLTSLGLPAGAAPGGLIAAALIPAHGWRSVFIFGGVTSLLVT 194 A+AL SE+ PERRR+ L + G G+ GG++AA L+P GWRSV +FGGV LL+ Sbjct: 134 AIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFGGVIPLLLL 193 Query: 195 AIVFCFLPESLRFLVEAGKAQSISANRSLRNLFGREA---SNVELHKK-EKTQNWSSITA 250 ++ LPES+R+LV G QS + R L + + + LH+ K S + Sbjct: 194 PVMVFALPESVRYLVAKG-GQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKGAPGSPVRQ 252 Query: 251 LFSDGRRAGTFLFWTVTFCNLLCLYFLANWLPVLLRDQGLDLGSALLAASAMQAGGLPGV 310 LF R GT L W+V F +LL +Y + NWLP L+ G+ L A A Q GG G Sbjct: 253 LFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMYQLGGTVGA 312 Query: 311 VSISYFSRKFGSTSTLCVTY 330 + I ++ +T LC TY Sbjct: 313 LVIGRMMDRYPATVVLCCTY 332 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 203 bits (517), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 117/327 (35%), Positives = 184/327 (56%), Gaps = 12/327 (3%) Query: 11 IEQAMEERPLGWYQWRILFICFICLMVDGFDAQALAYVAPVMRQELGISTSELGLIFSSS 70 + + ++ L YQ +L +CF M+DGFD A+ Y+AP +R+ ++ +L F + Sbjct: 12 VREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPAFGAG 71 Query: 71 LIGMLFGAFLLSPLADRFGRRPMMIAAMGICSVAMLLAPATASFSSLVAIRFVTGLGLGV 130 L G++ G+ L P+ADRFGR+P+++ ++ + VA L A+ S ++LV +RF+TGLGLG Sbjct: 72 LFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGLGG 131 Query: 131 ILPNALALVSEFSPERRRSILVMLTSLGLPAGAAPGGLIAAALIPAHGWRSVFIFGGVTS 190 +P + L +E+SP+R R +LV L+ G +G A GGL+AA ++P +GWR V + GGVT Sbjct: 132 AMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGVTP 191 Query: 191 LLVTAIVFCFLPESLRFLVEAGKAQSISANRSLRNLFGREASN-----VELHKKEKTQNW 245 L++ ++ ++PES++FL AQ +LR + R A + V Q Sbjct: 192 LVLLPVLALWMPESVQFL-----AQRPQCADALRQIVTRIAGHDHGDGVTFIGDRPAQEG 246 Query: 246 SSITA--LFSDGRRAGTFLFWTVTFCNLLCLYFLANWLPVLLRDQGLDLGSALLAASAMQ 303 + LFSDG T L W FC+L Y L +WLPV++RDQGL L A + + Sbjct: 247 APFPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVP 306 Query: 304 AGGLPGVVSISYFSRKFGSTSTLCVTY 330 GG G ++++ + GS L Y Sbjct: 307 LGGTIGAIALALLMDRAGSPRALIAAY 333 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 192 bits (488), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 113/324 (34%), Positives = 185/324 (57%), Gaps = 4/324 (1%) Query: 11 IEQAMEERPLGWYQWRILFICFICLMVDGFDAQALAYVAPVMRQELGISTSELGLIFSSS 70 ++ + +PL YQWRI+ +CF+ + +DG D A+ ++AP + Q+ GI + LG + S++ Sbjct: 14 VQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPVMSAA 73 Query: 71 LIGMLFGAFLLSPLADRFGRRPMMIAAMGICSVAMLLAPATASFSSLVAIRFVTGLGLGV 130 LIGM+FGA PLADR+GR+ +++AA+ + + L + + + L+A+RF+TGLGLG Sbjct: 74 LIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGLGLGA 133 Query: 131 ILPNALALVSEFSPERRRSILVMLTSLGLPAGAAPGGLIAAALIPAHGWRSVFIFGGVTS 190 +PNA L+SE++PER +S+LV G G A GG ++A LIP GW S+ + GG+ Sbjct: 134 AMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLGGLLP 193 Query: 191 LLVTAIVFCFLPESLRFLVEAGKAQSISANRSLRNLFGRE---ASNVELHKKEKTQNWSS 247 L++ ++ LPES R+LV + S + L + + A + + +++ Q + Sbjct: 194 LVLAVVLLFRLPESARYLVVRNRG-SERVRQVLAPIAPAQVALARSFHVPEQQTVQARNV 252 Query: 248 ITALFSDGRRAGTFLFWTVTFCNLLCLYFLANWLPVLLRDQGLDLGSALLAASAMQAGGL 307 +FS AGT L W F L+ +Y L +WLP L+RD G L A + Q GG+ Sbjct: 253 FAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGALFQFGGV 312 Query: 308 PGVVSISYFSRKFGSTSTLCVTYL 331 V++ + +F + + YL Sbjct: 313 LSAVAVGWAMDRFNPHKVIGLFYL 336 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 176 bits (446), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 107/326 (32%), Positives = 177/326 (54%), Gaps = 8/326 (2%) Query: 9 KTIEQAMEERPLGWYQWRILFICFICLMVDGFDAQALAYVAPVMRQELGISTSELGLIFS 68 + ++ ++ P+G QWR++ CF+ +M+DGFD A+ ++AP +R ++ +L +F Sbjct: 5 RDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFG 64 Query: 69 SSLIGMLFGAFLLSPLADRFGRRPMM---IAAMGICSVAMLLAPATASFSSLVAIRFVTG 125 + L+G+ GA L PL+DRFGR+ ++ + G S+A +P +LV +RF+TG Sbjct: 65 AGLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSP---DLQTLVFLRFLTG 121 Query: 126 LGLGVILPNALALVSEFSPERRRSILVMLTSLGLPAGAAPGGLIAAALIPAHGWRSVFIF 185 LGLG +PN + + SE+ P RRR LV L G G+A GG+++A L+P GW + + Sbjct: 122 LGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVL 181 Query: 186 GGVTSLLVTAIVFCFLPESLRFLVEAGKAQSISANRSLRNLFGREASNVELHKKEKTQ-N 244 GGV L++ + LPES R+ V Q++ A +++ + + + E Sbjct: 182 GGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIA-KTVSAITRERYVDTHFYLIESASVT 240 Query: 245 WSSITALFSDGRRAGTFLFWTVTFCNLLCLYFLANWLPVLLRDQGLDLGSALLAASAMQA 304 SI LF + T + W V F +LL +Y L++W+P LL +G+DL A +A Q Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 305 GGLPGVVSISYFSRKFGSTSTLCVTY 330 GG G +++ KF L ++Y Sbjct: 301 GGTLGALALGVLMDKFNPFRVLTLSY 326 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 176 bits (445), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 106/326 (32%), Positives = 176/326 (53%), Gaps = 8/326 (2%) Query: 9 KTIEQAMEERPLGWYQWRILFICFICLMVDGFDAQALAYVAPVMRQELGISTSELGLIFS 68 + ++ ++ P+G QWR++ CF+ +M+DGFD A+ ++AP +R ++ +L +F Sbjct: 5 RDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFG 64 Query: 69 SSLIGMLFGAFLLSPLADRFGRRPMM---IAAMGICSVAMLLAPATASFSSLVAIRFVTG 125 + L+ + GA L PL+DRFGR+ ++ + G S+A +P +LV +RF+TG Sbjct: 65 AGLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSP---DLQTLVFLRFLTG 121 Query: 126 LGLGVILPNALALVSEFSPERRRSILVMLTSLGLPAGAAPGGLIAAALIPAHGWRSVFIF 185 LGLG +PN + + SE+ P RRR LV L G G+A GG+++A L+P GW + + Sbjct: 122 LGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVL 181 Query: 186 GGVTSLLVTAIVFCFLPESLRFLVEAGKAQSISANRSLRNLFGREASNVELHKKEKTQ-N 244 GGV L++ + LPES R+ V Q++ A +++ + + + E Sbjct: 182 GGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIA-KTVSAITRERYVDTHFYLIESASVT 240 Query: 245 WSSITALFSDGRRAGTFLFWTVTFCNLLCLYFLANWLPVLLRDQGLDLGSALLAASAMQA 304 SI LF + T + W V F +LL +Y L++W+P LL +G+DL A +A Q Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 305 GGLPGVVSISYFSRKFGSTSTLCVTY 330 GG G +++ KF L ++Y Sbjct: 301 GGTLGALALGVLMDKFNPFRVLTLSY 326