BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0067.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 141 3e-33 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 123 9e-28 PA2091 [GEPR] COG0477 Permeases of the major facilitator superfa... 112 1e-24 RSp0107 [GEPR] COG0477 Permeases of the major facilitator superf... 98 4e-20 PA2589 [GEPR] COG0477 Permeases of the major facilitator superfa... 96 1e-19 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 141 bits (355), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 117/415 (28%), Positives = 198/415 (47%), Gaps = 12/415 (2%) Query: 19 RAIHRGWWMVAISFLG-LAFGQTSLAFLTLGVFMKPFNQEFGWTRGQVAIALSVGAFVLL 77 R IH GW +VA++FL LA L+F G F++P+ EF RG +++ ++ V Sbjct: 3 RKIHYGWIIVAVTFLTFLAVQGVRLSF---GAFVQPWETEFSMDRGSISLISTLSFIVYG 59 Query: 78 FTTPVVGRIIDRVGARKILLPSMAAFGVSMCSMYFLTGSLIHFYFMFAVVGVVGAAANNV 137 + P++G+++DR+GAR IL S GVS T F VV + A+NV Sbjct: 60 ISQPLIGKLVDRLGARFILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNV 119 Query: 138 SYVRILSAWFVRHRGLSIGIASSGVAAGQSFGITLAQNVITDQGWRMAYVALGASVLLVG 197 + +++ WF + RGL+ GI +G AGQ + + +I W+ V LG + ++ Sbjct: 120 AATVVITNWFNKKRGLAFGIIEAGFGAGQMILVPGSLMLIQWLDWKATVVILGFFLAVIV 179 Query: 198 LPIVALFIKNDPKDVGLEPCGA--DDVAGEKISLGYYVSKAEALRMPVFWALIF---LAF 252 PIV L ++N P + +EP G ++ S RM FW L+ + Sbjct: 180 FPIVLLLLRNHPSEKQVEPIGGVREEEETNTSPNSATFSNWSVFRMRPFWFLVLPFAICG 239 Query: 253 FMATALHGIQIHFVPLLLDAGLSPGQVTGLLVSVLSVGAIVGRVGTGFLFDRFFAPYVAI 312 F T L + H +PL D G S VT VS+L+ IVG + +G + DR+ + Sbjct: 240 FTTTGL--MDTHLIPLSHDHGFSTS-VTSAAVSLLAGFNIVGILLSGVIADRWSSRKFLF 296 Query: 313 GVFGLPIIGLLLVLNHVGLWGLCAGAFFFGIGLGSESDVLGYFTSRYFGLKSMAELYGYI 372 ++ + L+++++ L A FG+ + ++YF S+ + G++ Sbjct: 297 LLYVARALSLVILVHSHDPLLLLGFAILFGLVDFATVAPTQLLATQYFKRYSIGLMIGWL 356 Query: 373 FGAFMAGSSAGPALYGIVQGKTGNYDTTLFASIGMLMFVCLVCAFLPRFKDKNNQ 427 F + GS+ G + G++ +TG+Y +L+ SI +L+ + FLP + N Sbjct: 357 FLSHQVGSALGAYVPGLLYEQTGSYTVSLYVSIVILIVAAICNLFLPEPNKQRND 411 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 123 bits (308), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 112/423 (26%), Positives = 202/423 (47%), Gaps = 17/423 (4%) Query: 19 RAIHRGWWMVAISFLGLAFGQTSLAFLTLGVFMKPFNQEFGWTRGQVAIALSVGAFVLLF 78 + +H W +V+++FL L Q L+ G F++P+ ++F R +++ +V V Sbjct: 2 KRLHYAWIIVSVTFLILLAVQG--VRLSFGAFVEPWERQFSIDRSTISLISTVSFIVYGI 59 Query: 79 TTPVVGRIIDRVGARKILLPSMAAFGVSMCSMYFLTGSLIHFYFMFAVVGVVGAAANNVS 138 + PV+GR++D+ GAR +L S GVS+ Y +T F V + A+NV+ Sbjct: 60 SQPVIGRLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVA 119 Query: 139 YVRILSAWFVRHRGLSIGIASSGVAAGQSFGITLAQNVITDQGWRMAYVALGASVLLVGL 198 ++ WF + RGL+ GI +G AGQ + + +I W++ V LG ++++ Sbjct: 120 ASVLVVNWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVF 179 Query: 199 PIVALFIKNDPKDVGLEPCG-----ADDVAGEKISLGYYVSKAEALRMPVFWALIFLAFF 253 P L ++N+P + EP G + A + +L S A RM FW LIF F Sbjct: 180 PAALLMLRNNPSEKNTEPIGGLAASEKETAPKTTAL----SVAGMFRMRQFWFLIF-PFL 234 Query: 254 MA--TALHGIQIHFVPLLLDAGLSPGQVTGLLVSVLSVGAIVGRVGTGFLFDRFFAPYVA 311 + T + + H +P D G S VT VS+L+ I G + +G + DR+ + + Sbjct: 235 ICGFTTVGLMDTHLIPFSHDHGFST-TVTSAAVSLLAGFNIAGILLSGIVADRWSSRKIL 293 Query: 312 IGVFGLPIIGLLLVLNHVGLWGLCAGAFFFGIGLGSESDVLGYFTSRYFGLKSMAELYGY 371 ++ + + +++++ + L A A FG+ + ++YF S+ + G+ Sbjct: 294 CILYAVRALSIVILIYSHEPYLLLAFAILFGLVDFATVAPTQMLATQYFQNYSIGLMIGW 353 Query: 372 IFGAFMAGSSAGPALYGIVQGKTGNYDTTLFASIGMLMFVCLVCAFL--PRFKDKNNQAI 429 + A GS+ G + G++ TG Y + SIGML+ ++ L P +++ A+ Sbjct: 354 LSLAHQIGSALGAYVPGVIYTVTGEYTLAFYLSIGMLVLASVMNVMLREPAAVTRDSAAV 413 Query: 430 ADD 432 D Sbjct: 414 VDK 416 >PA2091 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 427 Score = 112 bits (281), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 113/394 (28%), Positives = 177/394 (44%), Gaps = 14/394 (3%) Query: 31 SFLGLAFGQTSLAFLTLGVFMKPFNQEFGWTRGQVAIALSVGAFVLLFTTPVVGRIIDRV 90 S +G+ FG T L + +F++P + W RGQ A+ +++ + ++P+ G ++DR Sbjct: 33 SVVGVIFGPTGLVISSFSLFIEPIAADLDWDRGQSALPVTLLGLAVALSSPLKGWLVDRW 92 Query: 91 GARKILLPSMAAFGVSMCSMYFLTGSLIHFYFMFAVVGVVGAAANNVSYVRILSAWFVRH 150 GAR ++LP AA + + S+ + + N+ Y RIL WF R Sbjct: 93 GARALVLPLTAALALCLASLALARSG---WQLYLLFALLGLLTPGNIPYARILGGWFERR 149 Query: 151 RGLSIGIASSGVAAGQSFGITLAQNVITDQGWRMAYVALGASVLLVGLPIVALFIKNDPK 210 RG + GI G G + L I GWR ++ G L+ LP++ + P Sbjct: 150 RGAAYGILGLGFGVGGPLALYLGSACIDAFGWRATFLVYGLLEGLLALPLLYALFRERPG 209 Query: 211 DV-GLEPCGADDVAGEKISLGYYVSKAEALRMPVFWALIFLAFFMATALHGIQIHFVPLL 269 D+ AD + G + +A R FW ++ A+ G+ +H VPLL Sbjct: 210 DLPQARRTPADALPG--------ATPGQAWRSADFWLIVGNLILGVFAVTGVMVHGVPLL 261 Query: 270 LDAGLSPGQVTGLLVSVLSVGAIVGRVGTGFLFDRFFAPYVAIGVFGLPIIGLLLVLNHV 329 + GLS T +L + L VG IV + G+L DR+ P +A+ L +GLLL+L Sbjct: 262 QERGLSREVATDVL-AALWVGMIVSQPALGYLLDRYDTPRIALPFALLAALGLLLLLLGG 320 Query: 330 GLWGLCAGAFFFGIGLGSESDVLGYFTSRYFGLKSMAELYGYIFG-AFMAGSSAGPALYG 388 L F G+G G E+ YF SRYFGL+ + +YG I F S G L G Sbjct: 321 PPALLWGAVFLIGLGAGGETGTTQYFVSRYFGLRHFSVIYGSIQPFTFAIAISLGSWLLG 380 Query: 389 IVQGKTGNYDTTLFASIGMLMFVCLVCAFLPRFK 422 + G+Y + +G + L R++ Sbjct: 381 YFYDRAGSYAGSTLVLLGAFGVAAGLLVMLGRYR 414 >RSp0107 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 432 Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 117/426 (27%), Positives = 197/426 (46%), Gaps = 32/426 (7%) Query: 22 HRGWWMVAISFLGLAFGQTSLAFLTLGVFMKPFNQEFGWTRGQVAIALSVGAFVLLFTTP 81 H GW +A+ FL L + A T V M P EFGW+RG +++A+S+G + T P Sbjct: 13 HYGWIALAVVFLILLCAAGTRA--TPSVMMLPLEHEFGWSRGTISLAISIGIALYGLTGP 70 Query: 82 VVGRIIDRVGARKILLPSMAAF--GVSMCSMYFLTGSLIHFYFMFAVVGVVGAAANNVSY 139 + G R +L ++ G ++ +M ++ + + G AA + Sbjct: 71 FAAASMQYFGIRPTVLGALVVLISGTALSAMMSQPWQMVLLWGVMVGGGTGVAAITLGAT 130 Query: 140 VRILSAWFVRHRGLSIGIASSGVAAGQSFGITLAQNVITDQGWRMAYVALGASVLLVGLP 199 V ++ WF HRGL++GI ++ A GQ + + V+ GWR V + A L++ LP Sbjct: 131 V--VNRWFTTHRGLAMGILTASSATGQLVFLPMMAAVVERHGWR-PVVLIVAGALVLLLP 187 Query: 200 IVALFIKNDPKDVGL----EPCGADDV----AGEKISLGYYVSKAEALRMPVFWALIFLA 251 IV L + PK VGL EP A + I+L + + +A+R FW L+F + Sbjct: 188 IVGLLLPESPKSVGLRTYGEPADAPEADHGPRANPIALAMH-TLMQAMRKRDFW-LLFAS 245 Query: 252 FFMATALHG--IQIHFVPLLLDAGLSPGQVTGL-LVSVLSVGAIVGRVGTGFLFDRFFAP 308 FF+ A I HF+ + D GL+ +V G L++ + + +VG +G+L DR+ + Sbjct: 246 FFICGASTNGYIGTHFIAMCADHGLT--EVKGASLLAAMGIFDLVGTTLSGWLSDRYNSR 303 Query: 309 YVAIGVFGLPIIGLLLVLNHVG--LWGLCAGAFFFGIGLGSESDVLGYFTSRYFGLKSMA 366 + +GL + L+ + G +GL A F+G+ + T+ FG + Sbjct: 304 VLLFWYYGLRGLSLIYLPYAFGFEFFGLPVFAIFYGLDWIATVPPTVRLTNDVFGKAAAP 363 Query: 367 ELYGYIFGAFMAGSSAGPALYGIVQGKTGNYDTTLFASIGMLMFVCLVCAFL----PRFK 422 ++G+I G++ G+++ GNY S G+ C+ AFL R + Sbjct: 364 IVFGWIVAGHQLGAAFATLGAGLMRASLGNYTLASMISGGL----CVAGAFLVLRIHRQR 419 Query: 423 DKNNQA 428 + QA Sbjct: 420 KPDAQA 425 >PA2589 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 404 Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 108/391 (27%), Positives = 180/391 (46%), Gaps = 11/391 (2%) Query: 31 SFLGLAFGQTSLAFLTLGVFMKPFNQEFGWTRGQVAIALSVGAFVLLFTTPVVGRIIDRV 90 S + + G T + T +F+ P + E+ W R +V++ +++ + T+P+ G +IDR Sbjct: 17 SVVAIMLGPTGILLNTFSLFIAPMSAEYAWDRAEVSLLVTLFGLAVAITSPLKGWLIDRW 76 Query: 91 GARKILLPSMAAFGVSMCSMYFLTGSLIHFYFMFAVVGVVGAAANNVSYVRILSAWFVRH 150 GAR+ +L AA + + + + ++ Y +F ++G++ A N+ Y RIL WF + Sbjct: 77 GARRTMLGLTAALSLPLLGLAAVN-AVWQLYALFLLIGLL--APGNLPYGRILGLWFRQR 133 Query: 151 RGLSIGIASSGVAAGQSFGITLAQNVITDQGWRMAYVALGASVLLVGLPIVALFIKNDPK 210 G++ G+ G G G+ + + GWR A++ G L + LP++A + Sbjct: 134 LGVAYGLLGLGFGVGGPLGLLVGHQSLEAWGWRGAFLVYGVLELGLALPLLAWLFREPAP 193 Query: 211 DVGLEPCGADDVAGEKISLGYYVSKAEALRMPVFWALIFLAFFMATALHGIQIHFVPLLL 270 D G+ A S + +A R FW ++ + GI H VP+L+ Sbjct: 194 DAGVAAGTAVAETALSGS-----TAPQAWRSASFWLVLGNQVLAVFVMSGIMTHGVPMLV 248 Query: 271 DAGLSPGQVTGLLVSVLSVGAIVGRVGTGFLFDRFFAPYVAIGVFGLPIIGLLLVLNHVG 330 + GLS G+ G +S L VG ++ + G+L DR P VA+ ++G+ L Sbjct: 249 ERGLSRGE-AGTALSALWVGMMLSQPLMGWLLDRVATPRVALPFALAAVLGMAWFLVGDT 307 Query: 331 LWGLCAGAFFFGIGLGSESDVLGYFTSRYFGLKSMAELYGYIFG-AFMAGSSAGPALYGI 389 GL F G+G G ES Y RYFGL+S +YG I F S G L G Sbjct: 308 PSGLWLAVFLVGLGGGGESGTTKYLLMRYFGLRSFGVIYGSIQPFTFALSISLGAYLLGW 367 Query: 390 VQGKTGNYDTTLFASIGML-MFVCLVCAFLP 419 + + Y T + + + C + AF P Sbjct: 368 LYDRAEGYGTAEWVLLAAFSLAACSLFAFRP 398