BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0064.p (248 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0958 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mac M... 164 1e-40 MTH973 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mth M... 132 8e-31 MJ0915 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mja M... 110 4e-24 RSp0722 Non COG 106 6e-23 PA3505 [R] COG1712 Predicted dinucleotide-utilizing enzyme Pae P... 103 5e-22 >MA0958 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mac Methanosarcina acetivorans str.C2A Length = 271 Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 95/253 (37%), Positives = 153/253 (60%), Gaps = 6/253 (2%) Query: 2 ALDKGMPGLELHAVAVRDPAKSAQWREML--INPPMIVDFDRLAECDIVVECAPASLMSD 59 A+D G EL+A+ +K+ + L P + + + D+++E A + + Sbjct: 19 AIDGGEVSAELYALCDSSESKALELAASLKTCKPSYMKIEELIRGVDLIIESASQNAVRF 78 Query: 60 IATPVLQAGKKLVVLSSGALLE---RPELLQLAKDKAAQIIVPTGALLGLDAVTAAAEGV 116 I L+AG +++LS GAL + R L LAK+ ++ P+GA++G+D + +A+ Sbjct: 79 IVPQALKAGCDVMILSVGALADEELRDTLFGLAKEHNCKLYFPSGAVVGIDGLNSASAAG 138 Query: 117 IHSVKMVTRKPVRGLLGAPYLEKNNIKIDGITAPTRIFSGTAREAAVGFPANLNVAVALS 176 I SV + TRKP GL+GAPY+ ++ I+++ + T +F G A EA FPAN+NVA +S Sbjct: 139 ISSVTLSTRKPPAGLMGAPYVVEHGIELEKLEKKTVLFEGPASEAVKAFPANVNVAATIS 198 Query: 177 LAGIGPDRTLLEIWADPSLERNTHTISVDADSASFSMTIENIPT-DNPKTGRITALSIIS 235 LAGIG +RT +++ ADPSL RN H I V+ + FS +EN+P+ +NPKT + ALS +S Sbjct: 199 LAGIGFERTRVKVIADPSLFRNVHEIIVEGEFGKFSTRVENLPSPENPKTSYLAALSAVS 258 Query: 236 LLRKIGAPMRVGS 248 L+KI P+++G+ Sbjct: 259 TLKKILNPVQIGT 271 >MTH973 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mth Methanothermobacter thermautotrophicus Length = 257 Score = 132 bits (332), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 87/216 (40%), Positives = 124/216 (57%), Gaps = 24/216 (11%) Query: 40 DRLAECDIVVECAPASLMSDIATPVLQAGKKLVVLSSGALLE---RPELLQLAKDKAAQI 96 D L E D+VVE A + D+ +L+AGK +VV+S GAL++ R L++LA A I Sbjct: 59 DMLPEVDLVVEAASPEAVRDLVPEILEAGKDVVVMSVGALMDPELREMLVELASLNDATI 118 Query: 97 IVPTGALLGLDAVTAAAEGVIHSVKMVTRKPVRGLLGAPYLEKNNIKIDGITAPTR--IF 154 VP+GA++GLD + AA+ G I SVK++TRKP R L GI+ + ++ Sbjct: 119 HVPSGAIVGLDGLKAASMGNIESVKLITRKPPRSL--------------GISMDEKKVLY 164 Query: 155 SGTAREAAVGFPANLNVAVALSLAGIGPDRTL-LEIWADPSLERNTHTISVDADSASFSM 213 G A EA FP N+NVA ALSLA DR + +EI ADP+++RN H ++V D F Sbjct: 165 RGRASEAVKKFPLNINVAAALSLA---CDRDVDVEIIADPAVDRNVHEVTVRGDFGEFKT 221 Query: 214 TIENIPTD-NPKTGRITALSIISLLRKIGAPMRVGS 248 EN+ NPKT + A S I LL+ + + +G+ Sbjct: 222 ITENVRCSVNPKTSVMAAYSAIKLLKSLSENIHIGT 257 >MJ0915 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mja Methanococcus jannaschii Length = 267 Score = 110 bits (274), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 74/209 (35%), Positives = 116/209 (55%), Gaps = 8/209 (3%) Query: 44 ECDIVVECAPASLMSDIATPVLQAGKKLVVLSSGALLERPELLQL---AKDKAAQIIVPT 100 + D+VVE A + +IA L K ++++S GAL ++ L+L AK +I +P+ Sbjct: 63 DLDLVVEAASIKAVEEIAEKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYLPS 122 Query: 101 GALLGLDAVTAAAEGVIHSVKMVTRKPVRGLLGAPYLEKNNIKIDGITAPTRIFSGTARE 160 GA+ GLDA+ A G I V + T KPV L A L+ K + I P +F G + Sbjct: 123 GAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDA--LKNLGYKPEDIKNPVIVFEGDVFK 180 Query: 161 AAVGFPANLNVAVALSLAGIGPDRTLLEIWADPSLERNTHTISVDADSASFSMTIENIP- 219 A FPAN+NV+V LS+A P + + I ADP+ + N H + V + + + IEN+P Sbjct: 181 AIKEFPANINVSVTLSIAAEFPAKVV--IVADPNAKLNKHELFVKSSIGTLRVCIENVPF 238 Query: 220 TDNPKTGRITALSIISLLRKIGAPMRVGS 248 +NP+T + A S + L+R + P++VG+ Sbjct: 239 EENPRTSALAAYSAVRLIRDLAEPVKVGT 267 >RSp0722 Non COG Length = 268 Score = 106 bits (264), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 69/200 (34%), Positives = 107/200 (53%), Gaps = 9/200 (4%) Query: 46 DIVVECAPASLMSDIATPVLQAGKKLVVLSSGALLE---RPELLQLAKDKAAQIIVPTGA 102 D++VECA + + P L+ G +V+S GAL E L A+ AQ+ + +GA Sbjct: 66 DLLVECAGHDALREHVVPALEQGIDCLVVSVGALSEPGLAERLEAAARRGHAQMQLLSGA 125 Query: 103 LLGLDAVTAAAEGVIHSVKMVTRKPVRGLLGAPYLEKNNIKIDGITAPTRIFSGTAREAA 162 + +DA+ AA G + +V RKP R G P + +D + T IF G A +AA Sbjct: 126 IGAIDALAAARVGGLDAVVYTGRKPPRAWKGTP--AERQFDLDALDRTTVIFEGKASDAA 183 Query: 163 VGFPANLNVAVALSLAGIGPDRTLLEIWADPSLERNTHTISVDADSASFSMTIENIP-TD 221 + FP N NVA L+LAG+G +RT + + ADP+++ N H + F + + P Sbjct: 184 LLFPKNANVAATLALAGLGMERTHVRLLADPTIDENIHHVEARGAFGGFELIMRGKPLAA 243 Query: 222 NPKTGRITALSIISLLRKIG 241 NPKT +AL++ S++R +G Sbjct: 244 NPKT---SALTVFSVVRALG 260 >PA3505 [R] COG1712 Predicted dinucleotide-utilizing enzyme Pae Pseudomonas aeruginosa Length = 267 Score = 103 bits (256), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 84/242 (34%), Positives = 122/242 (50%), Gaps = 14/242 (5%) Query: 8 PGLELHAVAV-RDPAKSAQWR-EMLINPPMIVDFDRLAEC-DIVVECAPASLMSDIATPV 64 P L + AV V RD + R L PP ++ E D++VECA + P Sbjct: 24 PQLRVDAVIVPRDSETQVRHRLASLRRPPRVLSALPAGERPDLLVECAGHRAIEQHVLPA 83 Query: 65 LQAGKKLVVLSSGALLERPELLQ----LAKDKAAQIIVPTGALLGLDAVTAAAEGVIHSV 120 L G +V+S GAL E P L++ A+ ++I + GA+ +DA++AA G + SV Sbjct: 84 LAQGIPCLVVSVGALSE-PGLVERLEAAAQAGGSRIELLPGAIGAIDALSAARVGGLESV 142 Query: 121 KMVTRKPVRGLLGAPYLEKNNIKIDGITAPTRIFSGTAREAAVGFPANLNVAVALSLAGI 180 + RKP LG P + + + IF G+AREAA +P N NVA LSLAG+ Sbjct: 143 RYTGRKPASAWLGTP--GETVCDLQRLEKARVIFDGSAREAARLYPKNANVAATLSLAGL 200 Query: 181 GPDRTLLEIWADPSLERNTHTISVDADSASFSMTIENIP-TDNPKTGRITALSIISLLRK 239 G DRT + + ADP N H + F +T+ P NPKT +AL++ S++R Sbjct: 201 GLDRTQVRLIADPESCENVHQVEASGAFGGFELTLRGKPLAANPKT---SALTVYSVVRA 257 Query: 240 IG 241 +G Sbjct: 258 LG 259