BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0061.p (399 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5522 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydroge... 208 2e-53 SMb20820 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrog... 208 2e-53 CC3525 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogen... 207 5e-53 mlr5000 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydroge... 206 5e-53 BMEII0557 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydro... 203 7e-52 >mll5522 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Mlo Mesorhizobium loti Length = 417 Score = 208 bits (529), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 134/381 (35%), Positives = 213/381 (55%), Gaps = 6/381 (1%) Query: 14 VVIVGSGLAAVSALEGMREAGYSGPVVMVGEERQMPYDRPPLSKMVLSEIGAEDKIFLRD 73 VVIVG+G A V A +RE GY GPV+++G+E ++PY +PPLSK + + A+ + LR Sbjct: 5 VVIVGAGHAGVQAAASLREDGYDGPVILIGDENELPYHKPPLSKTFIKDAEAKPQP-LRG 63 Query: 74 QSAYDALGATMLLGRSVIKIEAGNREVSLDDGTRLPYEKLLLATGSRPRILQGLSPSD-P 132 ++ Y G + +I+AG + + G L ++ L+LATGSRPR+L L SD Sbjct: 64 EAFYTGSVIDYRPGVRIERIDAGGHSLEISGGGVLAFDHLILATGSRPRLLP-LPGSDLS 122 Query: 133 GVFYLRTLDDSIALRAALKDASSLVVIGGGVIGLEVAAVAVKAGVSTTVIEAGNRLMARA 192 GV LR+L D+ +R + +V++GGG IGLE+AA AG + TV+EA +RL+ RA Sbjct: 123 GVLSLRSLADARLIRDLSARSEDVVILGGGFIGLEIAATLRAAGRTVTVVEAVDRLLGRA 182 Query: 193 ATPQLSALLEKVHRQNGVNVLCGASPTGFAFFN-NLHAISMADGTVLEADLLVVGIGVVP 251 P +++ + + GV +L G S N ++ A + G L A +++VGIG VP Sbjct: 183 VAPVVASHVRQRLEATGVRILTGTSIARLEGENGHVVAAITSSGEKLPARMVIVGIGAVP 242 Query: 252 ETSLASAAGIECGPAGIVVDGMGATNVEHIYAAGEVAHHFNAGSGGHERQENWHHAAAHG 311 LA AG+ GI VD ++V+ I A G+ A + + +GG R E+ +A Sbjct: 243 NVELAQDAGLTIA-NGIRVDHQMRSSVQDILAIGDAASYRHWFTGGDVRLESVQNATDQA 301 Query: 312 KHVGMSMIAPTDAYREISGYWSDQYDLNVQVFGSVA-GDKDVVRGDIEAKSFSVFHLLNE 370 + ++ DAY + +WSD D+ +Q+ G A GD VV GD+ FS++H + Sbjct: 302 RLAARTITGHADAYSAVPWFWSDIGDMKLQMVGLTAGGDSHVVLGDLPDNKFSIYHYAGD 361 Query: 371 TVIGVTAVNAPKELRTGKQLV 391 ++G+ +VN P + G++++ Sbjct: 362 RLLGIESVNRPGDHMLGRKML 382 >SMb20820 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Sme Sinorhizobium meliloti Length = 409 Score = 208 bits (529), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 126/359 (35%), Positives = 194/359 (54%), Gaps = 5/359 (1%) Query: 14 VVIVGSGLAAVSALEGMREAGYSGPVVMVGEERQMPYDRPPLSKMVLSEIGAEDKIFLRD 73 +VI+G+G A +RE G+ G + + G E +PY+RPPLSK L++ A F+ Sbjct: 4 IVIIGAGECGARAAFALREKGFGGEITLTGAEPHLPYERPPLSKDGLAQ--ASLPKFIAG 61 Query: 74 QSAYDALGATMLLGRSVIKIEAGNREVSLDDGTRLPYEKLLLATGSRPRILQGLSPSDPG 133 + Y+ T+L G + I+ ++ V+L DG L Y++LLLATG+RPR + + Sbjct: 62 AARYEEARITVLTGVTAESIDRVHKAVTLSDGVSLDYDRLLLATGARPRAFPRVPENAGR 121 Query: 134 VFYLRTLDDSIALRAALKDASSLVVIGGGVIGLEVAAVAVKAGVSTTVIEAGNRLMARAA 193 + LRT D++A+R AL + L VIGGG IGLE+AA A K G ++E R+++R Sbjct: 122 IRTLRTHADALAIRGALTPGARLAVIGGGFIGLELAATARKLGAEVVLVEGLPRVLSRGV 181 Query: 194 TPQLSALLEKVHRQNGVNVLCGASPTGFAFFNNLHAISMADGTVLEADLLVVGIGVVPET 253 +++ L+ + HR+ GV ++CGA + + +ADG +EADL+VVGIG VP T Sbjct: 182 PEEIAVLVAERHRREGVEIICGAQIAAIDGAGDGARLLLADGVDIEADLIVVGIGAVPNT 241 Query: 254 SLASAAGIECGPAGIVVD-GMGATNVEHIYAAGEVAHHFNAGSGGHE-RQENWHHAAAHG 311 LA AAG+ GI VD + ++ H+ A GG R E W +A G Sbjct: 242 ELAEAAGLAI-ENGIAVDERLCTSDPRHLCRPATAAPSLCPHYGGRRVRLEAWRNAQDQG 300 Query: 312 KHVGMSMIAPTDAYREISGYWSDQYDLNVQVFGSVAGDKDVVRGDIEAKSFSVFHLLNE 370 +++ + + +WSDQY+ +Q+ G G + VR D+E +F +FHL E Sbjct: 301 ALAAANLMGAGETMVSVPWFWSDQYEFTLQIAGLADGAETTVRRDMEEGAFILFHLDGE 359 >CC3525 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Ccr Caulobacter vibrioides Length = 412 Score = 207 bits (526), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 138/383 (36%), Positives = 195/383 (50%), Gaps = 3/383 (0%) Query: 14 VVIVGSGLAAVSALEGMREAGYSGPVVMVGEERQMPYDRPPLSKMVLSEIGAEDKIFLRD 73 VVIVG+G A S +R+ G+ G +V++G+E +PY RPPLSK L D + L+ Sbjct: 11 VVIVGAGHAGGSVAAFLRQYGHEGRIVLIGDEPLLPYQRPPLSKAWLKGEADADSLSLKP 70 Query: 74 QSAYDALGATMLLGRSVIKIEAGNREVSLDDGTRLPYEKLLLATGSRPRILQGLSPSDPG 133 Y + LG +I ++ V+L G +PY+ L+LATG+R R L G Sbjct: 71 AGWYADNNVMLRLGGVAERINRSDKTVALASGEVIPYDFLVLATGARARELPIPGADLAG 130 Query: 134 VFYLRTLDDSIALRAALKDASSLVVIGGGVIGLEVAAVAVKAGVSTTVIEAGNRLMARAA 193 V LRT D+ L+ AL L V+GGG +GLE AA A G VIE +R++AR A Sbjct: 131 VLALRTAADAELLKNALGPDKRLAVVGGGYVGLEAAASARALGSHAMVIERESRVLARVA 190 Query: 194 TPQLSALLEKVHRQNGVNVLCGASPTGFAFFN-NLHAISMADGTVLEADLLVVGIGVVPE 252 LS + H ++GV A F + ++ + DG V+ D+ +VG+G VP Sbjct: 191 CETLSHFFQDYHGKHGVAFELNAGVAAFEGHDGHVTGVRFNDGRVVACDVALVGVGAVPN 250 Query: 253 TSLASAAGIECGPAGIVVDGMGATNVEHIYAAGEVAHHFNAGSGGHERQENWHHAAAHGK 312 LA AG+ G+VVD T+ I+A G+V H R E+ +A K Sbjct: 251 DELAKDAGLSTA-NGVVVDLEARTDDPSIFAIGDVTHRPLPLYDRQFRLESVPNALEQAK 309 Query: 313 HVGMSMIAPTDAYREISGYWSDQYDLNVQVFG-SVAGDKDVVRGDIEAKSFSVFHLLNET 371 +++ E +WSDQYDL +Q+ G D+ VVRGD+ A F+VFHL + Sbjct: 310 QAASAILGRPGPAPETPWFWSDQYDLKLQIAGLPFDADRQVVRGDVAAAKFAVFHLKGDL 369 Query: 372 VIGVTAVNAPKELRTGKQLVRSK 394 V V AVNAP E GKQL+ + Sbjct: 370 VQAVEAVNAPPEFMAGKQLIAKR 392 >mlr5000 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Mlo Mesorhizobium loti Length = 412 Score = 206 bits (525), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 146/423 (34%), Positives = 214/423 (50%), Gaps = 53/423 (12%) Query: 12 RPVVIVGSGLAAVSALEGMREAGYSGPVVMVGEERQMPYDRPPLSKMVLSEIGAEDKIFL 71 R +VI+G+G A +R+ GY GPV +VG+E +PY+RPPLSK ++ E K Sbjct: 6 RGMVIIGAGECGGRAALTLRDLGYDGPVTLVGDEPHLPYERPPLSKEAMASDAPEIKAIA 65 Query: 72 RDQSAYDALGATMLLGRSV--------IKIEAGNREVSLDDGTRLPYEKLLLATGSRPRI 123 D +L RS+ I+ V L DG+ LPY+KLLLATG+ PR Sbjct: 66 SD---------AVLAERSIRHIHSVQAAAIDRAAHSVRLSDGSVLPYDKLLLATGATPRK 116 Query: 124 LQGLSPSDPGV----FYLRTLDDSIALRAALKDASSLVVIGGGVIGLEVAAVAVKAGVST 179 L S PG+ YLRT D++A+R L+ S + VIGGG IGLE+AA + + G + Sbjct: 117 L-----SMPGLGARCVYLRTFADALAIRGHLRAGSRIAVIGGGFIGLELAAASRRLGAAV 171 Query: 180 TVIEAGNRLMARAATPQLSALLEKVHRQNGVNVLCGASPTGFAFFNNLHAISMADGTVLE 239 TVIEA R++ R +++ ++ H GV+++CG A +++A G + Sbjct: 172 TVIEAQPRILMRGVPAEIAEIVHDAHIAEGVDIVCGQGIASIADDGRQVRVTLAGGREVS 231 Query: 240 ADLLVVGIGVVPETSLASAAGIECGPAGIVVDGMGATNVEHIYAAGEVAHHFNAGSGGHE 299 ADL ++GIG VP T LA+ AG+ GI VD ++ I+AAG+ A GG Sbjct: 232 ADLAIIGIGAVPVTGLAADAGLMI-DNGIAVDAELCSSDPDIFAAGDCCSFPLAVYGGRR 290 Query: 300 -RQENWHHAAAHGKHVGMSMIAPTDAYREISGYWSDQYDLNVQVFGSVAGDKDVVRGDIE 358 R E W +A G +M+ +A+ + +WSDQY L++Q+ G K+ VR D++ Sbjct: 291 VRLEAWRNAQEQGALAAKNMLDAGEAHAAVPWFWSDQYGLSLQIAGLSDEGKNTVRRDLD 350 Query: 359 AKSFSVFHL-----------------------LNETVIGVTAVNAPKELRTGKQLVRSKG 395 +F +FHL L E +IG A AP+ L G Q V+ K Sbjct: 351 DGAFILFHLAEDGTLVAASGIGPGNAVARDIRLAEMLIGKRAKPAPEAL--GSQAVKLKS 408 Query: 396 QLS 398 L+ Sbjct: 409 LLA 411 >BMEII0557 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Bme Brucella melitensis Length = 465 Score = 203 bits (516), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 126/364 (34%), Positives = 194/364 (53%), Gaps = 4/364 (1%) Query: 6 FSGDEVRPVVIVGSGLAAVSALEGMREAGYSGPVVMVGEERQMPYDRPPLSKMVLSEIGA 65 F G +I+G+G A A +R+ GY+G ++++ +E +PY +PPLSK L + Sbjct: 5 FGGPMDDRCIIIGAGHAGSQAAVSLRQEGYAGEIILINDETDIPYHKPPLSKSYL-KAPE 63 Query: 66 EDKIFLRDQSAYDALGATMLLGRSVIKIEAGNREVSLDDGTRLPYEKLLLATGSRPRILQ 125 + + LR +SAY ML G V + R V+L DG LP+ +L+ ATG+R RI Sbjct: 64 KGSLVLRPESAYRDNNIEMLFGAHVDAVSIAERTVTLGDGRVLPWSELVFATGARARIPD 123 Query: 126 GLSPSDPGVFYLRTLDDSIALRAALKDASSLVVIGGGVIGLEVAAVAVKAGVSTTVIEAG 185 + GV LR ++D+ + A + D ++V+IGGG IGLE+A A+ G T +IEA Sbjct: 124 VPGVALEGVVTLRRMEDARRIAAMMPDVRNVVIIGGGFIGLEMAHSAIALGKKTVLIEAA 183 Query: 186 NRLMARAATPQLSALLEKVHRQNGVNVLCGASPTGFAFFNNLH-AISMADGTVLEADLLV 244 R++ R+ +SA +E R + +L G N ++ DGT ADL+V Sbjct: 184 PRVLGRSVAAPVSAHVEARSRAADITLLTGLGVASIEGENGRAIGVTAGDGTFFPADLVV 243 Query: 245 VGIGVVPETSLASAAGIECGPAGIVVDGMGATNVEHIYAAGEVAHHFNAGSGGHERQENW 304 +G G VP LA+ AG+ GI VD T+ H+YA G+ A + + +G H R E+ Sbjct: 244 IGTGAVPNVELAAKAGLSI-DNGIRVDEHMRTSAPHVYAIGDCASYAHFHAGRHVRLESV 302 Query: 305 HHAAAHGKHVGMSMIAPTDAYREISGYWSDQYDLNVQVFG-SVAGDKDVVRGDIEAKSFS 363 +A KH +++ YRE++ +WSDQ D+ +Q G S D+ V+ G+ E +FS Sbjct: 303 QNATDQAKHFARTIVGRETPYREVAWFWSDQGDMKLQTAGLSFDADRHVLSGEPEENAFS 362 Query: 364 VFHL 367 VF Sbjct: 363 VFSF 366