BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0054.p (319 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA699 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 338 8e-93 AGl1616 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 318 9e-87 SMa1838 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 193 4e-49 AGl2846 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 192 1e-48 mll7048 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 180 4e-45 >AGpA699 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 325 Score = 338 bits (867), Expect = 8e-93, Method: Compositional matrix adjust. Identities = 175/310 (56%), Positives = 220/310 (70%) Query: 10 IAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLPR 69 I +++ LW+ L MP E I+ F + RE+ +AIVANPDPA+++ LP Sbjct: 16 IVLVTRMSEDAERLWLTSLSRKMPGETIVPFRQLDEAAREKADIAIVANPDPADIARLPN 75 Query: 70 LEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQK 129 L+WIHSVWAGVERL+A+LG+++L IVRLVDPQL+ TMAEAVLAWT YL R MP Y Q+ Sbjct: 76 LKWIHSVWAGVERLVAELGESRLPIVRLVDPQLSQTMAEAVLAWTYYLFRDMPAYANFQR 135 Query: 130 LRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGND 189 R+W+ Y P T+ +LGLGALG +A L AGF + GWSR+ K+I VQ F G+ Sbjct: 136 QRVWQQLAYRRPQDVTIGLLGLGALGAESAARLRYAGFNVIGWSRSHKEIDGVQTFHGDR 195 Query: 190 GLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALDS 249 GL+E+L ++ IL+CLLPLT ETR L+DA ++S+LP GA LINFARG I+ DL ALDS Sbjct: 196 GLEELLGRSEILVCLLPLTDETRGLIDAVRLSLLPEGASLINFARGPIVVADDLIRALDS 255 Query: 250 THLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGAI 309 + HAVLDVF+VEPLPP+ WDHP +TVLPH SAPT+R TA+AIVA NI YR SGA+ Sbjct: 256 GAMKHAVLDVFDVEPLPPDNKLWDHPAITVLPHISAPTDRETAAAIVAGNILTYRSSGAL 315 Query: 310 PAHVDTRRGY 319 P VD RGY Sbjct: 316 PPTVDLARGY 325 >AGl1616 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 314 Score = 318 bits (815), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 165/311 (53%), Positives = 225/311 (72%) Query: 9 PIAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLP 68 PIAF+S+ + +W + L+ AMPEE IL+FS++SA ++ + AIVANPDPA+++ LP Sbjct: 4 PIAFVSRMNAETEAVWKQALRAAMPEEDILSFSELSAEQKSRVDFAIVANPDPADIAALP 63 Query: 69 RLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQ 128 L WIHS+WAGVERL+ +LG+ IVRL DP+L+ MAEAVLAWT YL R MP Y++ Q Sbjct: 64 SLTWIHSLWAGVERLVLELGEKAPPIVRLKDPELSRVMAEAVLAWTYYLQRDMPAYRKNQ 123 Query: 129 KLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGN 188 + LW+ +Y P + T+ +LGLGALG AAA+ L AGF + GWSR+ K I V+ +G+ Sbjct: 124 EKALWQELDYRHPGEMTIGLLGLGALGRAAAERLTHAGFNVSGWSRSEKAIAGVETLTGD 183 Query: 189 DGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALD 248 DGL+ +L +++IL+CL+PLT TR LLDA +++++ GA LINFARGA+I DL +ALD Sbjct: 184 DGLQTLLEKSDILVCLVPLTDATRGLLDAGRLAVMKQGAALINFARGAVIVADDLLSALD 243 Query: 249 STHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGA 308 S ++HAVLDVFE EPLP W HP+VTVLPH SAPT+R +++ IVA N+ +R +G Sbjct: 244 SGRISHAVLDVFEQEPLPTASSFWRHPKVTVLPHISAPTSRESSARIVAGNVRIWRETGR 303 Query: 309 IPAHVDTRRGY 319 +P VD RGY Sbjct: 304 LPDTVDMIRGY 314 >SMa1838 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Sme Sinorhizobium meliloti Length = 326 Score = 193 bits (491), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 111/318 (34%), Positives = 172/318 (54%), Gaps = 5/318 (1%) Query: 3 QDISRDPIAFISQADHALSTLWIKELQLAMPEEKILAFS-DMSAIEREQCRVAIVANPDP 61 + R +AF+ +D ++ + +P+ + F+ D +A++ + R I P Sbjct: 13 HSVRRRAMAFLFNSDAKRGAIFAETFARELPD---IPFAVDPAAVDPDAVRYLITWTV-P 68 Query: 62 AELSTLPRLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQM 121 L+ LE + S+ AGV++ D +++VR+V+ + M E V L HR + Sbjct: 69 DNLARYRSLEILFSIGAGVDQFRIDAVPPHVRVVRMVEDGIVRMMQEYVTLAVLAHHRNL 128 Query: 122 PLYKQQQKLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKN 181 P Y +QQ+ W+A + ++ V +LGLG LG A L GF L GWSR+P +I+ Sbjct: 129 PAYLEQQQGENWQAIAPVQAVERRVGVLGLGMLGTAVLDRLKPFGFPLSGWSRSPHEIEG 188 Query: 182 VQCFSGNDGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDL 241 V+C SG +GL +L T+IL+CLLPLT ETR L+A+ + LPAGA L++ RG + Sbjct: 189 VRCLSGRNGLDTLLGSTDILVCLLPLTDETRGFLNAQLFARLPAGAALVHVGRGPQLDHD 248 Query: 242 DLRAALDSTHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIE 301 L LD HL+ A++DV + EPLP W HP++ + PH ++ T TA+ V +NI+ Sbjct: 249 ALVEGLDKGHLSGAMVDVTDPEPLPSGHRFWTHPKILLTPHIASVTQPETAARAVIENIK 308 Query: 302 NYRLSGAIPAHVDTRRGY 319 +R VD RRGY Sbjct: 309 RHRQGLEPIGLVDRRRGY 326 >AGl2846 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 349 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 118/312 (37%), Positives = 174/312 (55%), Gaps = 7/312 (2%) Query: 10 IAFISQADHALSTLWIKELQLAMPEEKILAFS-DMSAIEREQCRVAIVANPDPAELSTLP 68 + F +D ++ + L +P+ L FS D +++ + R +++ P ++ Sbjct: 43 MTFFFNSDAKRGEIFRQALARDLPD---LPFSMDAASVNPDAVRY-LISWTVPEDIGRYR 98 Query: 69 RLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQ 128 LE + S+ AGV++ D +K+VR+VD + M E V L LHR +P Y QQ Sbjct: 99 NLEILFSIGAGVDQFHIDAVPPHVKVVRMVDEGITRMMQEYVSLGVLALHRNLPAYLGQQ 158 Query: 129 KLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGN 188 + LWKA + V +LGLG LG AA + L GF L GWSR+P++I V C G Sbjct: 159 RQGLWKAVPQRQAEECRVGVLGLGMLGVAALERLKPFGFPLSGWSRSPREIDGVTCHHGE 218 Query: 189 DGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALD 248 GL + L ++IL+CLLPLT ET LL++E++ MLP GA L++ RG + L ALD Sbjct: 219 AGLAKTLTTSDILVCLLPLTEETTGLLNSERLGMLPEGAGLVHAGRGRQLDHDALIDALD 278 Query: 249 STHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGA 308 S L+ AVLDV E EPLP + W HP++ + PH ++ T ++A+ V +NI+ Y+ SG Sbjct: 279 SGRLSGAVLDVTEPEPLPEDHRFWAHPKILLTPHVASVTQPHSAARTVVENIKRYQ-SGL 337 Query: 309 IP-AHVDTRRGY 319 P VD RGY Sbjct: 338 EPLGLVDRNRGY 349 >mll7048 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Mlo Mesorhizobium loti Length = 307 Score = 180 bits (457), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 107/311 (34%), Positives = 165/311 (53%), Gaps = 5/311 (1%) Query: 10 IAFISQADHALSTLWIKELQLAMPEEKILAFS-DMSAIEREQCRVAIVANPDPAELSTLP 68 + F+ +D ++ + +PE + F+ D + ++ + R I P L+ Sbjct: 1 MTFLFNSDARRGAIFAEAFARELPE---VPFTMDAAKVDPDAVRYLITWTA-PDNLARYR 56 Query: 69 RLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQ 128 LE + S+ AGV++ D ++KIVR ++ + M E L LHR +P Y QQ Sbjct: 57 NLEILFSIGAGVDQFRLDGVPERVKIVRTIEEGIVRMMQEYAALAVLALHRNLPAYLAQQ 116 Query: 129 KLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGN 188 + W+ + + + +LGLG LG+A L GF L GWSR+P++I+ V C G Sbjct: 117 RAGEWRDIPQLQAGSRRIGVLGLGQLGQAVLGRLKPFGFPLAGWSRSPRRIEGVTCHHGE 176 Query: 189 DGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALD 248 GL+ MLA ++I+ICLLPLT +TR L+A + LP GA L++ RG + L AALD Sbjct: 177 PGLEGMLAVSDIVICLLPLTEDTRGFLNAGLFAKLPRGAALVHTGRGPQLDHEALVAALD 236 Query: 249 STHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGA 308 HL+ A++DV + EPLP + W HP++ + PH ++ T TA+ V +NI +R Sbjct: 237 HGHLSAAMIDVTDPEPLPTSHPFWRHPKIILTPHVASVTQPVTAARAVIENIRRHRAGLD 296 Query: 309 IPAHVDTRRGY 319 VD RGY Sbjct: 297 PIGLVDRSRGY 307