BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0046.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value proP [GEPR] COG0477 Permeases of the major facilitator superfami... 283 5e-76 ZproP [GEPR] COG0477 Permeases of the major facilitator superfam... 283 5e-76 ECs5093 [GEPR] COG0477 Permeases of the major facilitator superf... 283 5e-76 STM4290 [GEPR] COG0477 Permeases of the major facilitator superf... 283 6e-76 AGl1071 [GEPR] COG0477 Permeases of the major facilitator superf... 262 1e-69 >proP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 500 Score = 283 bits (725), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 158/424 (37%), Positives = 247/424 (58%), Gaps = 10/424 (2%) Query: 32 RKAAIAASAGTAIEYYEFGVYGYMAATIGPLFFPSTDATASLLAILAVFGSAFLMRPIGG 91 RKA AAS G A+E+++FGVYG++A +G +FFP D + ++A LA F FL+RP+GG Sbjct: 24 RKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGG 83 Query: 92 IVLGRLGDRIGRRGILLVTVIGMGIATGLIGLLPTASTAGILAPLMLLLVRLVQGFFAGG 151 + G LGD+ GR+ IL +T++ M I+T IGL+P+ T GI AP++LL+ ++ QGF GG Sbjct: 84 LFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGG 143 Query: 152 EVTGAAAYVAECAPPGKRGFYGAFTPVGVAVGGAVAAALCGITSVLLTPAQMAEWGWRIP 211 E TGA+ +VAE +P KRGF G++ G G + A + + S ++ A +WGWRIP Sbjct: 144 EYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIP 203 Query: 212 FLLAIPMVLISTAVRRRVEESAAFQEF-----QAHNEPV----KAPLREVLTQHPGKIFK 262 F +A+P+ +I +R +EE+ AFQ+ Q E + K +E+ T++ + Sbjct: 204 FFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLT 263 Query: 263 VMALAFGQNVGYYVGLVFMNIYMTTYLKYDKTAIYWIMAAVGVTMAMLMPFFGSLSDRWG 322 + L NV YY+ L +M Y++ L Y + I+ A+ + M + P G LSDR+G Sbjct: 264 CIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFG 323 Query: 323 RRPVLAIGFIGYMVLVWPMMFLMDQQSLPLAALAMFIMALPLPIVQSVGYPTYAEQFPTK 382 RRP + +G + VL P L++ + L + ++A+ L V T FPT Sbjct: 324 RRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTH 383 Query: 383 VRYTGMAFSINIGAILGGGVTPYLATSLMATTGNLKSPAFLLIAAAVLSLLALLTVHETA 442 +RY+ +A + NI ++L G+TP LA L+ ++ NL PA+ L+ AV+ L+ +T+ ETA Sbjct: 384 IRYSALAAAFNI-SVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETA 442 Query: 443 KEKL 446 L Sbjct: 443 NRPL 446 >ZproP [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 500 Score = 283 bits (725), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 158/424 (37%), Positives = 247/424 (58%), Gaps = 10/424 (2%) Query: 32 RKAAIAASAGTAIEYYEFGVYGYMAATIGPLFFPSTDATASLLAILAVFGSAFLMRPIGG 91 RKA AAS G A+E+++FGVYG++A +G +FFP D + ++A LA F FL+RP+GG Sbjct: 24 RKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGG 83 Query: 92 IVLGRLGDRIGRRGILLVTVIGMGIATGLIGLLPTASTAGILAPLMLLLVRLVQGFFAGG 151 + G LGD+ GR+ IL +T++ M I+T IGL+P+ T GI AP++LL+ ++ QGF GG Sbjct: 84 LFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGG 143 Query: 152 EVTGAAAYVAECAPPGKRGFYGAFTPVGVAVGGAVAAALCGITSVLLTPAQMAEWGWRIP 211 E TGA+ +VAE +P KRGF G++ G G + A + + S ++ A +WGWRIP Sbjct: 144 EYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIP 203 Query: 212 FLLAIPMVLISTAVRRRVEESAAFQEF-----QAHNEPV----KAPLREVLTQHPGKIFK 262 F +A+P+ +I +R +EE+ AFQ+ Q E + K +E+ T++ + Sbjct: 204 FFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLT 263 Query: 263 VMALAFGQNVGYYVGLVFMNIYMTTYLKYDKTAIYWIMAAVGVTMAMLMPFFGSLSDRWG 322 + L NV YY+ L +M Y++ L Y + I+ A+ + M + P G LSDR+G Sbjct: 264 CIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFG 323 Query: 323 RRPVLAIGFIGYMVLVWPMMFLMDQQSLPLAALAMFIMALPLPIVQSVGYPTYAEQFPTK 382 RRP + +G + VL P L++ + L + ++A+ L V T FPT Sbjct: 324 RRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTH 383 Query: 383 VRYTGMAFSINIGAILGGGVTPYLATSLMATTGNLKSPAFLLIAAAVLSLLALLTVHETA 442 +RY+ +A + NI ++L G+TP LA L+ ++ NL PA+ L+ AV+ L+ +T+ ETA Sbjct: 384 IRYSALAAAFNI-SVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETA 442 Query: 443 KEKL 446 L Sbjct: 443 NRPL 446 >ECs5093 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 500 Score = 283 bits (725), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 158/424 (37%), Positives = 247/424 (58%), Gaps = 10/424 (2%) Query: 32 RKAAIAASAGTAIEYYEFGVYGYMAATIGPLFFPSTDATASLLAILAVFGSAFLMRPIGG 91 RKA AAS G A+E+++FGVYG++A +G +FFP D + ++A LA F FL+RP+GG Sbjct: 24 RKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGG 83 Query: 92 IVLGRLGDRIGRRGILLVTVIGMGIATGLIGLLPTASTAGILAPLMLLLVRLVQGFFAGG 151 + G LGD+ GR+ IL +T++ M I+T IGL+P+ T GI AP++LL+ ++ QGF GG Sbjct: 84 LFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGG 143 Query: 152 EVTGAAAYVAECAPPGKRGFYGAFTPVGVAVGGAVAAALCGITSVLLTPAQMAEWGWRIP 211 E TGA+ +VAE +P KRGF G++ G G + A + + S ++ A +WGWRIP Sbjct: 144 EYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIP 203 Query: 212 FLLAIPMVLISTAVRRRVEESAAFQEF-----QAHNEPV----KAPLREVLTQHPGKIFK 262 F +A+P+ +I +R +EE+ AFQ+ Q E + K +E+ T++ + Sbjct: 204 FFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLT 263 Query: 263 VMALAFGQNVGYYVGLVFMNIYMTTYLKYDKTAIYWIMAAVGVTMAMLMPFFGSLSDRWG 322 + L NV YY+ L +M Y++ L Y + I+ A+ + M + P G LSDR+G Sbjct: 264 CIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFG 323 Query: 323 RRPVLAIGFIGYMVLVWPMMFLMDQQSLPLAALAMFIMALPLPIVQSVGYPTYAEQFPTK 382 RRP + +G + VL P L++ + L + ++A+ L V T FPT Sbjct: 324 RRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTH 383 Query: 383 VRYTGMAFSINIGAILGGGVTPYLATSLMATTGNLKSPAFLLIAAAVLSLLALLTVHETA 442 +RY+ +A + NI ++L G+TP LA L+ ++ NL PA+ L+ AV+ L+ +T+ ETA Sbjct: 384 IRYSALAAAFNI-SVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETA 442 Query: 443 KEKL 446 L Sbjct: 443 NRPL 446 >STM4290 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 500 Score = 283 bits (724), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 158/424 (37%), Positives = 246/424 (58%), Gaps = 10/424 (2%) Query: 32 RKAAIAASAGTAIEYYEFGVYGYMAATIGPLFFPSTDATASLLAILAVFGSAFLMRPIGG 91 RKA AAS G A+E+++FGVYG++A +G +FFP D + ++A LA F FL+RP+GG Sbjct: 24 RKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMIAALATFSVPFLIRPLGG 83 Query: 92 IVLGRLGDRIGRRGILLVTVIGMGIATGLIGLLPTASTAGILAPLMLLLVRLVQGFFAGG 151 + G LGD+ GR+ IL +T++ M I+T IGL+P+ +T GI AP++LLL ++ QGF GG Sbjct: 84 LFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYATIGIWAPILLLLCKMAQGFSVGG 143 Query: 152 EVTGAAAYVAECAPPGKRGFYGAFTPVGVAVGGAVAAALCGITSVLLTPAQMAEWGWRIP 211 E TGA+ +VAE +P KRGF G++ G G + A + + S ++ EWGWRIP Sbjct: 144 EYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLEWGWRIP 203 Query: 212 FLLAIPMVLISTAVRRRVEESAAFQEF-----QAHNEPV----KAPLREVLTQHPGKIFK 262 F +A+P+ +I +R +EE+ AFQ+ Q E + K +E+ T+H + Sbjct: 204 FFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLS 263 Query: 263 VMALAFGQNVGYYVGLVFMNIYMTTYLKYDKTAIYWIMAAVGVTMAMLMPFFGSLSDRWG 322 + L NV YY+ L +M Y++ L Y + I+ A+ + M + P G LSDR+G Sbjct: 264 CIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFG 323 Query: 323 RRPVLAIGFIGYMVLVWPMMFLMDQQSLPLAALAMFIMALPLPIVQSVGYPTYAEQFPTK 382 RRP + +G I L P L++ + L + ++A+ L V T FPT Sbjct: 324 RRPFVIMGSIALFALAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTH 383 Query: 383 VRYTGMAFSINIGAILGGGVTPYLATSLMATTGNLKSPAFLLIAAAVLSLLALLTVHETA 442 +RY+ +A + NI ++L G+TP LA L+ ++ +L PA+ L+ AV+ L+ +++ ETA Sbjct: 384 IRYSALAAAFNI-SVLIAGLTPTLAAWLVESSQDLMMPAYYLMVIAVIGLITGISMKETA 442 Query: 443 KEKL 446 L Sbjct: 443 NRPL 446 >AGl1071 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 516 Score = 262 bits (669), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 159/428 (37%), Positives = 237/428 (55%), Gaps = 18/428 (4%) Query: 32 RKAAIAASAGTAIEYYEFGVYGYMAATIGPLFFPSTDATASLLAILAVFGSAFLMRPIGG 91 +KA AA+ G A+E+++FGVYG++A +G +FFP +A LA F FL+RP+GG Sbjct: 34 KKAVTAAALGNAMEWFDFGVYGFVAYAVGKVFFPDAAPAVQTVAALATFSVPFLIRPLGG 93 Query: 92 IVLGRLGDRIGRRGILLVTVIGMGIATGLIGLLPTASTAGILAPLMLLLVRLVQGFFAGG 151 I G +GD+ GR+ +L +T+I M +T IGL+P +T GI AP++LLL +LVQGF GG Sbjct: 94 IFFGAMGDKFGRQKVLSLTIIIMAASTFCIGLIPGYATIGIWAPILLLLCKLVQGFSVGG 153 Query: 152 EVTGAAAYVAECAPPGKRGFYGAFTPVGVAVGGAVAAALCGITSVLLTPAQMAEWGWRIP 211 E TGAA +VAE AP KRG+ G++ G G + A L + S + A+ +WGWRIP Sbjct: 154 EYTGAAIFVAEYAPDRKRGYLGSWLDFGSIAGFVLGAGLVVLLSSAMGEAKFLDWGWRIP 213 Query: 212 FLLAIPMVLISTAVRRRVEESAAF---------QEFQAHNEPVKAPLREVLTQHPGKIFK 262 F LA P+ LI +R EE+ AF ++ Q+ E P+ E+ +H F+ Sbjct: 214 FFLAAPLGLIGLYLRHAAEETPAFTERLQRAEEEDRQSLKERPMVPIAEIAREH----FR 269 Query: 263 VMALAFGQ----NVGYYVGLVFMNIYMTTYLKYDKTAIYWIMAAVGVTMAMLMPFFGSLS 318 +A+ G NV YY+ L +M Y++ L Y + I+ AV V M + P G LS Sbjct: 270 SLAICIGMVLVTNVTYYMLLTYMPTYLSKTLNYSEDHGVLIIIAVMVGMLFVQPAIGLLS 329 Query: 319 DRWGRRPVLAIGFIGYMVLVWPMMFLMDQQSLPLAALAMFIMALPLPIVQSVGYPTYAEQ 378 DR GR+P LA G + L P L+ + + I+A+ L + + T Sbjct: 330 DRIGRKPFLAAGSTAILFLSLPAFHLIASGQVVQIFFGLLILAVALNCLIGIMASTLPAL 389 Query: 379 FPTKVRYTGMAFSINIGAILGGGVTPYLATSLMATTGNLKSPAFLLIAAAVLSLLALLTV 438 FP ++RY+ +A + NI +I+ G+TP + L+ T N+ PA+ L+ AAV ++ + Sbjct: 390 FPARIRYSALAIAFNI-SIIVAGLTPTVTAWLVEVTENIYMPAYYLMVAAVFGIVTTFFL 448 Query: 439 HETAKEKL 446 ETA L Sbjct: 449 KETANRPL 456