BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0074.p (432 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ycdG [F] COG2233 Xanthine/uracil permeases Eco Escherichia coli K12 609 e-174 ZycdG [F] COG2233 Xanthine/uracil permeases EcZ Escherichia coli... 607 e-173 ECs1252 [F] COG2233 Xanthine/uracil permeases Ecs Escherichia co... 607 e-173 AGl3468 [F] COG2233 Xanthine/uracil permeases Atu Agrobacterium ... 514 e-145 BMEII0825 Non COG 471 e-132 >ycdG [F] COG2233 Xanthine/uracil permeases Eco Escherichia coli K12 Length = 464 Score = 609 bits (1570), Expect = e-174, Method: Compositional matrix adjust. Identities = 303/425 (71%), Positives = 366/425 (86%), Gaps = 2/425 (0%) Query: 6 FPQWRVRSGTSDGQGQVIAADERLPMPQTVAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 FP W+++S +++ V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 FPHWQLKSTSTESG--VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLLVGGRVPSYLGSSFAFIGLVIAVTGYAGQGPNANLGVALGGIVACGVVY 125 MSG+GTLLFF + GGRVPSYLGSS AF+G+VIA TG+ GQG N N+ +ALGGI+ACG+VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 TLIGLLVGIVGTRWIETLMPPVVTGSVVAVIGLNLAPIAVKGVTGNNFDAWMALGTVLCV 185 T+IGL+V +GTRWIE LMPPVVTG+VV IGLNLAPIAVK V+ + FD+WMA+ TVLC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCI 205 Query: 186 GLVAVFTRGMMQRLLILIGLLLAYVIYAILTNGAGLGKPIDFSSVANAAWFGIPGFAAPV 245 GLVAVFTRGM+QRLLIL+GL++A ++Y ++TN GLGK +DF+ V++AAWFG+P F+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FKAEAMALLAPVAIILVAENLGHIKAVSAMTGQNLDKYMGRAFIGDGLATILSGSVGGTG 305 F +AM L+APVA+ILVAENLGH+KAV+ MTG+N+D YMGRAF+GDGLAT+LSGSVGG+G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAIVLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA++LGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKLGGFALGGIGTATFGAILLYA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L LGGF LGGIGTATFGAILL A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLRKR 430 LL ++ Sbjct: 446 LLSRK 450 >ZycdG [F] COG2233 Xanthine/uracil permeases EcZ Escherichia coli O157:H7 EDL933 Length = 464 Score = 607 bits (1565), Expect = e-173, Method: Compositional matrix adjust. Identities = 302/425 (71%), Positives = 364/425 (85%), Gaps = 2/425 (0%) Query: 6 FPQWRVRSGTSDGQGQVIAADERLPMPQTVAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 P W+++S +++ V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 LPHWQLKSTSTESG--VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLLVGGRVPSYLGSSFAFIGLVIAVTGYAGQGPNANLGVALGGIVACGVVY 125 MSG+GTLLFF + GGRVPSYLGSS AF+G+VIA TG+ GQG N N+ +ALGGI+ACG+VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 TLIGLLVGIVGTRWIETLMPPVVTGSVVAVIGLNLAPIAVKGVTGNNFDAWMALGTVLCV 185 T+IGL+V +GTRWIE LMPPVVTG+VV IGLNLAPIAVK V+ + FD+WMA+ TVLC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASGFDSWMAVMTVLCI 205 Query: 186 GLVAVFTRGMMQRLLILIGLLLAYVIYAILTNGAGLGKPIDFSSVANAAWFGIPGFAAPV 245 GLVAVFTRGM+QRLLIL+GL++A ++Y ++TN GLGK +DF+ V++AAWFG+P F+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FKAEAMALLAPVAIILVAENLGHIKAVSAMTGQNLDKYMGRAFIGDGLATILSGSVGGTG 305 F +AM L+APVA+ILVAENLGH+KAV+ MTG+N+D YMGRAF+GDGLAT+LSGSVG +G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGSSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAIVLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA++LGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKLGGFALGGIGTATFGAILLYA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L LGGF LGGIGTATFGAILL A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLRKR 430 LL +R Sbjct: 446 LLSRR 450 >ECs1252 [F] COG2233 Xanthine/uracil permeases Ecs Escherichia coli O157:H7 Length = 464 Score = 607 bits (1565), Expect = e-173, Method: Compositional matrix adjust. Identities = 302/425 (71%), Positives = 364/425 (85%), Gaps = 2/425 (0%) Query: 6 FPQWRVRSGTSDGQGQVIAADERLPMPQTVAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 P W+++S +++ V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 LPHWQLKSTSTESG--VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLLVGGRVPSYLGSSFAFIGLVIAVTGYAGQGPNANLGVALGGIVACGVVY 125 MSG+GTLLFF + GGRVPSYLGSS AF+G+VIA TG+ GQG N N+ +ALGGI+ACG+VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 TLIGLLVGIVGTRWIETLMPPVVTGSVVAVIGLNLAPIAVKGVTGNNFDAWMALGTVLCV 185 T+IGL+V +GTRWIE LMPPVVTG+VV IGLNLAPIAVK V+ + FD+WMA+ TVLC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASGFDSWMAVMTVLCI 205 Query: 186 GLVAVFTRGMMQRLLILIGLLLAYVIYAILTNGAGLGKPIDFSSVANAAWFGIPGFAAPV 245 GLVAVFTRGM+QRLLIL+GL++A ++Y ++TN GLGK +DF+ V++AAWFG+P F+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FKAEAMALLAPVAIILVAENLGHIKAVSAMTGQNLDKYMGRAFIGDGLATILSGSVGGTG 305 F +AM L+APVA+ILVAENLGH+KAV+ MTG+N+D YMGRAF+GDGLAT+LSGSVG +G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGSSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAIVLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA++LGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKLGGFALGGIGTATFGAILLYA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L LGGF LGGIGTATFGAILL A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLRKR 430 LL +R Sbjct: 446 LLSRR 450 >AGl3468 [F] COG2233 Xanthine/uracil permeases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 502 Score = 514 bits (1323), Expect = e-145, Method: Compositional matrix adjust. Identities = 269/433 (62%), Positives = 337/433 (77%), Gaps = 14/433 (3%) Query: 3 GSYFPQWRVRSGTSDGQGQVIAADERLPMPQTVAMGVQHVVAMFGSTVLAPLLMGFDPNL 62 G YFP+WR+++ +G+++ DERLP QT +G+QHVVAMFGSTVLAPL+MGFDPN+ Sbjct: 67 GGYFPRWRLKT-----EGRIMP-DERLPAGQTAVLGLQHVVAMFGSTVLAPLIMGFDPNV 120 Query: 63 AILMSGVGTLLFFLLVGGRVPSYLGSSFAFIGLVIAVTGYAGQGPNANLGVALGGIVACG 122 +IL SG+ TL+FF+ VGGRVPSYLGSSFAFIG V+ TG A + ++ +ALGGI+A G Sbjct: 121 SILFSGISTLIFFIAVGGRVPSYLGSSFAFIGPVLVATGAAAGAASPDIALALGGIIAAG 180 Query: 123 VVYTLIGLLVGIVGTRWIETLMPPVVTGSVVAVIGLNLAPIAVKGVTG--------NNFD 174 V+Y LIG++V IVG WIE LMPPV+TG++VA IGL LAPIA+ +G + Sbjct: 181 VLYALIGVIVMIVGHNWIEKLMPPVLTGAIVAAIGLVLAPIAIASASGTGPGNPDGDQLS 240 Query: 175 AWMALGTVLCVGLVAVFTRGMMQRLLILIGLLLAYVIYAILTNGAGLGKPIDFSSVANAA 234 W+A+ TV VG +AV+ GM +RL IL+G +AY+ Y +L NG GLGKP+DF+ VA AA Sbjct: 241 RWIAILTVTSVGAIAVYAPGMTRRLPILLGGAIAYLAYLVLANGFGLGKPVDFAGVAAAA 300 Query: 235 WFGIPGFAAPVFKAEAMALLAPVAIILVAENLGHIKAVSAMTGQNLDKYMGRAFIGDGLA 294 WFG+P F PVF A A+AL+APV +ILVAENLGHIKA+ AMTG+NLD Y+GRAFIGDG+A Sbjct: 301 WFGLPAFTTPVFSAPAIALIAPVVVILVAENLGHIKAIGAMTGRNLDPYLGRAFIGDGIA 360 Query: 295 TILSGSVGGTGVTTYAENIGVMAVTKIYSTLVFVVAAVIAIVLGFSPKFGAVILTIPGAV 354 TI SG+ GGTG+TTYAEN+GVMA+T+I+STLVF+VAA++AI+LGFSPKFGA+I TIPG V Sbjct: 361 TIFSGAFGGTGMTTYAENMGVMAITRIFSTLVFIVAALVAIILGFSPKFGALIQTIPGPV 420 Query: 355 LGGVSIVVFGLITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKLGGFALGGIG 414 +GG+S+VVFGLI + RIWVENKVDFS NLI + LVLGAG+F L + GF L GIG Sbjct: 421 IGGLSVVVFGLIAATAGRIWVENKVDFSEPRNLITVGIALVLGAGNFKLNVAGFTLDGIG 480 Query: 415 TATFGAILLYALL 427 TAT GAI Y LL Sbjct: 481 TATIGAIAFYHLL 493 >BMEII0825 Non COG Length = 426 Score = 471 bits (1212), Expect = e-132, Method: Compositional matrix adjust. Identities = 244/423 (57%), Positives = 320/423 (75%), Gaps = 6/423 (1%) Query: 5 YFPQWRVRSGTSDGQGQVIAADERLPMPQTVAMGVQHVVAMFGSTVLAPLLMGFDPNLAI 64 YFP WR+ S V+ DERLP V MG+QH++AM GST++APLLMGFDPN+A+ Sbjct: 3 YFPSWRLTSNA------VVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAV 56 Query: 65 LMSGVGTLLFFLLVGGRVPSYLGSSFAFIGLVIAVTGYAGQGPNANLGVALGGIVACGVV 124 SG+GTLLFFL+ GRVPSYLGSSFAFI +VIA TGY+G GPN N+ +ALGGI+ACG + Sbjct: 57 FFSGIGTLLFFLITAGRVPSYLGSSFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGAL 116 Query: 125 YTLIGLLVGIVGTRWIETLMPPVVTGSVVAVIGLNLAPIAVKGVTGNNFDAWMALGTVLC 184 Y+LIGL+V +GT W+E LMPP VTG++ IGLNLAP+A+ + G +AL TVLC Sbjct: 117 YSLIGLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQLKGTGAHTSIALLTVLC 176 Query: 185 VGLVAVFTRGMMQRLLILIGLLLAYVIYAILTNGAGLGKPIDFSSVANAAWFGIPGFAAP 244 + +++ + +RL +L LL Y++ I NG G+ IDF++V NAAWFG+P F P Sbjct: 177 MAMISAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTP 236 Query: 245 VFKAEAMALLAPVAIILVAENLGHIKAVSAMTGQNLDKYMGRAFIGDGLATILSGSVGGT 304 F +A+ L+APVAI+LVAENLGHIKA+ ++TG+N+D Y+GR F DGLAT++SG+ GGT Sbjct: 237 AFNWQAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGT 296 Query: 305 GVTTYAENIGVMAVTKIYSTLVFVVAAVIAIVLGFSPKFGAVILTIPGAVLGGVSIVVFG 364 GVTTYAENIGVMA+TK+YSTL+FV+AA++A++LG SPKFGA++ TIP VL G+++ VFG Sbjct: 297 GVTTYAENIGVMAMTKVYSTLIFVIAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFG 356 Query: 365 LITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKLGGFALGGIGTATFGAILLY 424 LI + ARIW+ NKVDF+++ NL V L+ GAGDFTL +G FALGGI T+T A++LY Sbjct: 357 LIASAMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNFALGGIATSTLAALVLY 416 Query: 425 ALL 427 LL Sbjct: 417 QLL 419