BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0031.0147.p         (242 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSp0355 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto...   236   3e-62
HP1483 [H] COG2226 Methylase involved in ubiquinone/menaquinone ...    68   2e-11
CAC3419 [QR] COG0500 SAM-dependent methyltransferases Cac Clostr...    67   3e-11
jhp1376 [H] COG2226 Methylase involved in ubiquinone/menaquinone...    65   1e-10
ML1723 [QR] COG0500 SAM-dependent methyltransferases Mle Mycobac...    62   9e-10

>RSp0355 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia
           solanacearum
          Length = 246

 Score =  236 bits (602), Expect = 3e-62,   Method: Compositional matrix adjust.
 Identities = 124/226 (54%), Positives = 157/226 (69%), Gaps = 2/226 (0%)

Query: 16  VPESAFGIWFLQTHTWTLHVLERAFKDLEPLIPDRRASYPVVADVGCGWGRSLIKLHERF 75
           VPE+AFGIWFL+THTW  HVL  A  DL+ LI       PV+ADVGCG G S   L   F
Sbjct: 17  VPETAFGIWFLRTHTWAHHVLRVAVNDLKRLITTSLPVAPVIADVGCGQGISFRLLESAF 76

Query: 76  APQRLIGMDINPDMLEASAKEAAGAGIRAELIQCSSSHMTLEDNSVDLLFCHQTFHHLIE 135
           APQR+IG+D +   L A+ + AA      +L+    + + L D SVD++FCHQTFHHL+E
Sbjct: 77  APQRMIGIDFHRPSLAAAKQAAAALATPVDLLHGDCAALPLPDASVDMVFCHQTFHHLVE 136

Query: 136 QEEAIQEFFRVLKPGGVLLFAESTKRYIHSWMIRLLFRHPMEVQKTAGEYLALVRSAGFQ 195
           Q+ A+ EF RVLKPGG+LLFAEST+ YI SW+IRLLFRHPM VQK+A  YL ++R+ GF 
Sbjct: 137 QDRALAEFHRVLKPGGLLLFAESTEVYIKSWVIRLLFRHPMHVQKSAQGYLDMIRAGGFA 196

Query: 196 VAPQSISYPYLWWSR-EDLGLMERVLRIKPN-AVREETLINLVAVK 239
              ++IS PYLWWSR  D GL+ER+   +P    R ETL+N+VA+K
Sbjct: 197 FEDRNISLPYLWWSRARDFGLLERLGLHRPKPGKRRETLVNVVAIK 242


>HP1483 [H] COG2226 Methylase involved in ubiquinone/menaquinone
           biosynthesis Hpy Helicobacter pylori 26695
          Length = 246

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 55/178 (30%), Positives = 92/178 (51%), Gaps = 15/178 (8%)

Query: 31  WTLHVLERAFKDLEPLIPDRRASYPVVADVGCGWGRSLIK-----LHERFAPQRLIGMDI 85
           W     E AF  LE    +++A   V  DV CG G  L+      L+     +  +G+D 
Sbjct: 38  WRERACEHAFLFLE----NKKALRLV--DVACGTGDMLVAWQKSALNCGIEFKECLGIDP 91

Query: 86  NPDMLEASAKEAAGAGIRAELIQCSSSHMT-LEDNSVDLLFCHQTFHHLIEQEEAIQEFF 144
           + +MLE + K+      +A  IQ  +  +  +E+NSVD+L       +++E++EA++EFF
Sbjct: 92  SNNMLELAIKKCEELENKASFIQAQAKDLKGVENNSVDILSIAYGLRNVVERQEALKEFF 151

Query: 145 RVLKPGGVLLFAESTKRYIHSWMIRLLFRHPMEVQKTAGEYLALVRSAG-FQVAPQSI 201
           RVLKP GVL+  E  K+   +W+ ++   +  +V    G   A+ ++ G +   PQSI
Sbjct: 152 RVLKPRGVLVILEFLKKDNPTWLDKISGFYTNKVLPLVGG--AISKNYGAYSYLPQSI 207


>CAC3419 [QR] COG0500 SAM-dependent methyltransferases Cac Clostridium
           acetobutylicum
          Length = 207

 Score = 67.0 bits (162), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 4/120 (3%)

Query: 51  RASYPVVADVGCGWGRSLIKLHERFAPQRLIGMDINPDMLEASAKEAAGAGIRAELIQCS 110
           RA+   V DVGCG G +++K+  +     L G+D++  M+E + K   G   RAEL    
Sbjct: 45  RANPKTVLDVGCGTG-NVLKILAKDENLSLYGLDLSEKMIEIAKKNLKG---RAELKLGD 100

Query: 111 SSHMTLEDNSVDLLFCHQTFHHLIEQEEAIQEFFRVLKPGGVLLFAESTKRYIHSWMIRL 170
           S +M  + NS D++ C+ +FHH    ++ + E  R+LK  G L+  + T   I+  ++ L
Sbjct: 101 SENMPWKSNSFDVIVCNASFHHYPNPKKVLIEMKRILKKDGTLIIGDPTAPVIYRQILNL 160


>jhp1376 [H] COG2226 Methylase involved in ubiquinone/menaquinone
           biosynthesis jHp Helicobacter pylori J99
          Length = 246

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 54/178 (30%), Positives = 91/178 (51%), Gaps = 15/178 (8%)

Query: 31  WTLHVLERAFKDLEPLIPDRRASYPVVADVGCGWGRSLIK-----LHERFAPQRLIGMDI 85
           W     E AF  LE    +++A   V  DV CG G  L+      L+     +  +G+D 
Sbjct: 38  WRQRACEHAFLFLE----NKKALRLV--DVACGTGDMLVAWQKSALNCGIEFKECLGIDP 91

Query: 86  NPDMLEASAKEAAGAGIRAELIQCSSSHMT-LEDNSVDLLFCHQTFHHLIEQEEAIQEFF 144
           + +MLE + K+      +A  IQ  +  +  +E+NSVD+L       +++E++EA++EFF
Sbjct: 92  SNNMLELAIKKCEELENKASFIQAQAKDLKGVENNSVDILSIAYGLRNIVERQEALKEFF 151

Query: 145 RVLKPGGVLLFAESTKRYIHSWMIRLLFRHPMEVQKTAGEYLALVRSAG-FQVAPQSI 201
           RVLK  GVL+  E  K+   +W+ ++   +  +V    G   A+ ++ G +   PQSI
Sbjct: 152 RVLKTRGVLVILEFLKKDNPTWLDKISGFYTNKVLPLVGG--AISKNYGAYSYLPQSI 207


>ML1723 [QR] COG0500 SAM-dependent methyltransferases Mle Mycobacterium
           leprae
          Length = 327

 Score = 62.4 bits (150), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 3/117 (2%)

Query: 43  LEPLIPDRRAS---YPVVADVGCGWGRSLIKLHERFAPQRLIGMDINPDMLEASAKEAAG 99
            + ++PD   +   Y    ++GCG G  L+ L +    +R    D++P M++ + +    
Sbjct: 64  FDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSGVARRGSVTDLSPGMVKIATRNGQS 123

Query: 100 AGIRAELIQCSSSHMTLEDNSVDLLFCHQTFHHLIEQEEAIQEFFRVLKPGGVLLFA 156
            G+        +  +  +DN+ DL+  H   HH+ + E +++E  RVLKPGG  +FA
Sbjct: 124 LGLDINGRVADAEGIPYDDNTFDLVVGHAVLHHIPDVELSLREVLRVLKPGGRFVFA 180