BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0127.p (222 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl379 [CHR] COG1052 Lactate dehydrogenase and related dehydroge... 236 4e-62 BMEII0313 [CHR] COG1052 Lactate dehydrogenase and related dehydr... 234 9e-62 YPO2536 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 233 3e-61 SMc04462 [CHR] COG1052 Lactate dehydrogenase and related dehydro... 223 3e-58 AGl723 [CHR] COG1052 Lactate dehydrogenase and related dehydroge... 219 5e-57 >AGl379 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 311 Score = 236 bits (601), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 122/220 (55%), Positives = 154/220 (70%), Gaps = 1/220 (0%) Query: 1 VTNTPDVLTDDVADFAMTLLLSTARRVVDADRFARSGEWKKGPFALTTKVTGSRLGIVGL 60 V+NTPDVLT DVAD A+ L+L+ AR+V AD+ R+G+W KG L+T+V G R GI GL Sbjct: 92 VSNTPDVLTADVADLALGLVLAQARKVPQADQHVRTGQWLKGDMGLSTRVAGRRYGIFGL 151 Query: 61 GRIGKAIARRAAAFDMEISYHNRSPQSDVPYRYVADLKTLAGEVDFLVLSMPGGARARAL 120 GRIG+AIA+R FD ISY R+ + DV Y Y ++ LA D L+++ A R + Sbjct: 152 GRIGQAIAKRLEGFDARISYTARN-RRDVAYDYHDSIEELAANCDVLIIAAAATAETRHI 210 Query: 121 INAEVLDALGPKGFLINVARGSVVDEAALIKALQEGRIAGAGLDVFENEPNVPEALAKLP 180 +NA+VL ALGP+G L+NVARGS+VDE AL++AL G I GA LDVFE+EP VPEAL Sbjct: 211 VNADVLKALGPQGVLVNVARGSLVDEKALVEALSSGMIGGAALDVFEDEPRVPEALFAFE 270 Query: 181 NLTLTPHMASGTVITRTAMADLAFDNLQAHFSGKPLLTPV 220 N+TL PH+ SGT TR AMADL NL AHF+G+ L TPV Sbjct: 271 NVTLAPHIGSGTHQTRRAMADLVLANLDAHFAGRELPTPV 310 >BMEII0313 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Bme Brucella melitensis Length = 324 Score = 234 bits (598), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 124/224 (55%), Positives = 150/224 (66%), Gaps = 2/224 (0%) Query: 1 VTNTPDVLTDDVADFAMTLLLSTARRVVDADRFARSGEWKKGPFALTTKVT--GSRLGIV 58 VTNTPDVLT++VAD + LL+ T R + A F R GEW K +K++ G ++GI Sbjct: 92 VTNTPDVLTEEVADTTIGLLIDTVRELSKAQEFLRRGEWGKQVRYPLSKLSLRGRKVGIF 151 Query: 59 GLGRIGKAIARRAAAFDMEISYHNRSPQSDVPYRYVADLKTLAGEVDFLVLSMPGGARAR 118 GLGRIGKA+ARR AF + I+YHNR +DV Y Y LK LAG VD L+L PGGA Sbjct: 152 GLGRIGKAVARRIEAFGLPIAYHNRRKAADVAYDYYPSLKELAGAVDTLILVAPGGAETT 211 Query: 119 ALINAEVLDALGPKGFLINVARGSVVDEAALIKALQEGRIAGAGLDVFENEPNVPEALAK 178 +N EVL ALGP+G LIN+ RGSVVDE AL +AL++G IA AGLDVF NEP+VP+AL Sbjct: 212 RAVNMEVLQALGPEGVLINIGRGSVVDEEALAQALKDGTIAAAGLDVFANEPHVPQALLD 271 Query: 179 LPNLTLTPHMASGTVITRTAMADLAFDNLQAHFSGKPLLTPVPR 222 PN L PH+ S +V TR AMADL DNL A F +TPVP Sbjct: 272 APNTVLLPHIGSASVKTRRAMADLVVDNLIAWFDSGTAITPVPE 315 >YPO2536 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Ype Yersinia pestis Length = 316 Score = 233 bits (594), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 112/214 (52%), Positives = 154/214 (71%) Query: 1 VTNTPDVLTDDVADFAMTLLLSTARRVVDADRFARSGEWKKGPFALTTKVTGSRLGIVGL 60 VT TP VLTDDVAD A+ L+++T+RR A +F RSGEW G L++KVTG RLGI G+ Sbjct: 95 VTTTPGVLTDDVADTALGLIIATSRRFYQASQFLRSGEWPNGSLPLSSKVTGKRLGIFGM 154 Query: 61 GRIGKAIARRAAAFDMEISYHNRSPQSDVPYRYVADLKTLAGEVDFLVLSMPGGARARAL 120 GRIG+AIARRA FDM+I+Y + S +PY+YV DL +LA + D LV+++ GG + L Sbjct: 155 GRIGRAIARRAVGFDMQIAYTDTVHDSSLPYQYVPDLISLAKQSDILVVAISGGKDSAGL 214 Query: 121 INAEVLDALGPKGFLINVARGSVVDEAALIKALQEGRIAGAGLDVFENEPNVPEALAKLP 180 ++ + A+ G LIN+ARGS+V++ LI ALQ+ +I GAGLDVF +EP+VP+AL ++ Sbjct: 215 VDKAIFAAMPNHGILINIARGSMVNQDDLISALQQQQIGGAGLDVFADEPHVPQALIEMD 274 Query: 181 NLTLTPHMASGTVITRTAMADLAFDNLQAHFSGK 214 N+ L PH+AS T TR M+D+ F N+ AHFSG+ Sbjct: 275 NVFLLPHIASATTDTRIQMSDIVFSNILAHFSGE 308 >SMc04462 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Sme Sinorhizobium meliloti Length = 315 Score = 223 bits (567), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 124/222 (55%), Positives = 158/222 (71%), Gaps = 2/222 (0%) Query: 1 VTNTPDVLTDDVADFAMTLLLSTARRVVDADRFARSGEW-KKGPFALT-TKVTGSRLGIV 58 VTNTPDVLT++VAD A+ LLL+T R + A+++ R G W ++G F L+ + G +G+ Sbjct: 82 VTNTPDVLTEEVADTAIGLLLNTLRLLPQAEQWLRQGRWVREGAFPLSPLSLRGRTVGLF 141 Query: 59 GLGRIGKAIARRAAAFDMEISYHNRSPQSDVPYRYVADLKTLAGEVDFLVLSMPGGARAR 118 GLGRIG AIARR AF + I+YH R+P+ + + Y L +A VD L++ +PG A Sbjct: 142 GLGRIGLAIARRLEAFGVSIAYHTRTPREGLGFTYHPTLVGMAEAVDTLIVIVPGTASTL 201 Query: 119 ALINAEVLDALGPKGFLINVARGSVVDEAALIKALQEGRIAGAGLDVFENEPNVPEALAK 178 +NA+VL ALGPKG LINV RGS VDEAAL+ ALQ G IAGAGLDVFENEPNVPEAL Sbjct: 202 KAVNADVLSALGPKGVLINVGRGSTVDEAALVTALQNGTIAGAGLDVFENEPNVPEALLS 261 Query: 179 LPNLTLTPHMASGTVITRTAMADLAFDNLQAHFSGKPLLTPV 220 PN++L PH+AS +V+TR AM+DL DNL+A FS LTPV Sbjct: 262 FPNVSLLPHVASASVVTRNAMSDLVVDNLKAWFSTGEALTPV 303 >AGl723 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 320 Score = 219 bits (557), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 112/224 (50%), Positives = 148/224 (66%), Gaps = 2/224 (0%) Query: 1 VTNTPDVLTDDVADFAMTLLLSTARRVVDADRFARSGEW-KKGPFALTT-KVTGSRLGIV 58 VTNTPDVL D+VAD + LL++T RR+ A+ + R G+W +GPFAL+ + G ++G+ Sbjct: 92 VTNTPDVLNDEVADTTIALLINTVRRLYQAETWLRDGKWVGEGPFALSPFSLRGRKVGLF 151 Query: 59 GLGRIGKAIARRAAAFDMEISYHNRSPQSDVPYRYVADLKTLAGEVDFLVLSMPGGARAR 118 G+GRIG+ IA+R F +EI YH RS + ++ Y Y LK +A VD L+ +PG Sbjct: 152 GMGRIGQEIAKRLEPFKVEIGYHTRSKRDELSYTYYGSLKEMAEAVDILICIVPGTPETH 211 Query: 119 ALINAEVLDALGPKGFLINVARGSVVDEAALIKALQEGRIAGAGLDVFENEPNVPEALAK 178 INA++L ALG +G INV RGS VDE AL++ALQ G + AGLDVF EP VPEA Sbjct: 212 KAINADILAALGAQGVFINVGRGSSVDEDALLQALQSGALGAAGLDVFYAEPKVPEAFLA 271 Query: 179 LPNLTLTPHMASGTVITRTAMADLAFDNLQAHFSGKPLLTPVPR 222 LPN++L PH+AS +V TR AMADL DN+ F +LTPVP Sbjct: 272 LPNVSLLPHVASASVPTRNAMADLVADNILGWFRDGKVLTPVPE 315