BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0042.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0405 [T] COG1493 Serine kinase of the HPr protein, regulates ... 326 3e-89 NMA0947 [T] COG1493 Serine kinase of the HPr protein, regulates ... 228 9e-60 NMB0737 [T] COG1493 Serine kinase of the HPr protein, regulates ... 228 9e-60 XF1406 [T] COG1493 Serine kinase of the HPr protein, regulates c... 207 3e-53 lin2626 [T] COG1493 Serine kinase of the HPr protein, regulates ... 153 5e-37 >RSc0405 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Rso Ralstonia solanacearum Length = 324 Score = 326 bits (836), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 162/266 (60%), Positives = 199/266 (74%), Gaps = 8/266 (3%) Query: 4 FTALSIQQLYEENRESLQLGWFAGFPGGERLISGD----AASAADQVGHLNLIHPGRIQV 59 T ++ Q ++++N L+L W AG G +R D A SAAD VGHLNLIHP RIQV Sbjct: 3 LTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQV 62 Query: 60 FGHQETEYYQRLSNTSRAYQTAELVAGEPPAFIIAQGLATPPDILAICDEKNIPLFSTPL 119 G E YYQRLS +R Q EL+ EPP ++A G+ PPD+ C + PLF++P+ Sbjct: 63 LGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPI 122 Query: 120 PAAQVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLV 179 +A VID+LR+YLS+ A ++TMHGVF+D+LG+GVLI G+SGLGKSELGLELISR HGLV Sbjct: 123 SSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHGLV 182 Query: 180 ADDAVEFARIAPNMIEGRCPPLLQNLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVR 239 ADDAV+F R+ P+ IEGRCPPLLQNLLEVRGLGLLDIK IFGETAVRRKM++KLIV LVR Sbjct: 183 ADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQLVR 242 Query: 240 RSTLEENYERLPLDAQFEDVLAKGLP 265 R+ E +ERLPLD+Q+ DVL GLP Sbjct: 243 RNDGE--FERLPLDSQYMDVL--GLP 264 >NMA0947 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism NmA Neisseria meningitidis Z2491 Length = 320 Score = 228 bits (582), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 124/277 (44%), Positives = 171/277 (61%), Gaps = 10/277 (3%) Query: 1 MPSFTALSIQQLYEENRESLQLGWFAGFPGGERLISGDAASAA-DQVGHLNLIHPGRIQV 59 MPS +S+++L+++N+ LQL W AG G + I +A VGHLN IHP +IQV Sbjct: 1 MPS---ISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALVGHLNFIHPNQIQV 57 Query: 60 FGHQETEYYQRLSNTSRAYQTAELVAGEPPAFIIAQGLATPPDILAICDEKNIPLFSTPL 119 G E+EY RL + YQ +L I+A GL P + C + +IPL ++ L Sbjct: 58 VGLAESEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLRDYCHKNDIPLLTSKL 117 Query: 120 PAAQVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLV 179 + ++D LR+YL + LA HGVF+DV +GVLITG SGLGKSEL LELISR H L+ Sbjct: 118 ESPYLMDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGLGKSELALELISRGHSLI 177 Query: 180 ADDAVEFARIAPNMIEGRCPPLLQNLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVR 239 ADDAVE RI P +EGRC P+L++ LEVRGLG+L+I+ IFGET++R K L+LI++LV Sbjct: 178 ADDAVELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIFGETSIRPKKILQLIINLVE 237 Query: 240 -RSTLEENYERLPLDAQFEDVL-----AKGLPAAISR 270 + +RL + + E +L + LP A+ R Sbjct: 238 ADDEYMKQLDRLSIRTETESILNVNVRSVTLPVAVGR 274 >NMB0737 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Nme Neisseria meningitidis MC58 Length = 320 Score = 228 bits (582), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 124/277 (44%), Positives = 171/277 (61%), Gaps = 10/277 (3%) Query: 1 MPSFTALSIQQLYEENRESLQLGWFAGFPGGERLISGDAASAA-DQVGHLNLIHPGRIQV 59 MPS +S+++L+++N+ LQL W AG G + I +A VGHLN IHP +IQV Sbjct: 1 MPS---ISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALVGHLNFIHPNQIQV 57 Query: 60 FGHQETEYYQRLSNTSRAYQTAELVAGEPPAFIIAQGLATPPDILAICDEKNIPLFSTPL 119 G E+EY RL + YQ +L I+A GL P + C + +IPL ++ L Sbjct: 58 VGLAESEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLRDYCHKNDIPLLTSKL 117 Query: 120 PAAQVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLV 179 + ++D LR+YL + LA HGVF+DV +GVLITG SGLGKSEL LELISR H L+ Sbjct: 118 ESPYLMDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGLGKSELALELISRGHSLI 177 Query: 180 ADDAVEFARIAPNMIEGRCPPLLQNLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVR 239 ADDAVE RI P +EGRC P+L++ LEVRGLG+L+I+ IFGET++R K L+LI++LV Sbjct: 178 ADDAVELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIFGETSIRPKKILQLIINLVE 237 Query: 240 -RSTLEENYERLPLDAQFEDVL-----AKGLPAAISR 270 + +RL + + E +L + LP A+ R Sbjct: 238 ADDEYMKQLDRLSIRTETESILNVNVRSVTLPVAVGR 274 >XF1406 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Xfa Xylella fastidiosa 9a5c Length = 316 Score = 207 bits (526), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 107/265 (40%), Positives = 168/265 (63%), Gaps = 4/265 (1%) Query: 5 TALSIQQLYEENRESLQLGWFAGFPGGERLI-SGDA-ASAADQVGHLNLIHPGRIQVFGH 62 T+++ ++L++ R+ L L W AG G R I SGD A G+LN I+P ++Q+ G Sbjct: 3 TSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQILGT 62 Query: 63 QETEYYQRLSNTSRAYQTAELVAGEPPAFIIAQGLATPPDILAICDEKNIPLFSTPLPAA 122 +E + L R +++ +P +I++ + P D+ D IPL+ +P Sbjct: 63 EELTWLDSLEPNKRKETIEKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKRGH 122 Query: 123 QVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADD 182 +++++L +L++ LA + T+HGVFM++ +GVLITGE+G GKSEL LEL+SR H LVADD Sbjct: 123 ELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVADD 182 Query: 183 AVEFARIAPNMIEGRCPPLLQNLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVRRST 242 A EF +IAP++++G CP +LQ+LLEVRGLG+L+++ +FG+TA+++ L+LIVHL + T Sbjct: 183 APEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKPIT 242 Query: 243 --LEENYERLPLDAQFEDVLAKGLP 265 YERL D+ VL +P Sbjct: 243 EPTPSGYERLTGDSGTRHVLDLDVP 267 >lin2626 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Lin Listeria innocua Length = 312 Score = 153 bits (386), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 139/251 (55%), Gaps = 3/251 (1%) Query: 17 RESLQLGWFAGFPGGER--LISGDAASAADQVGHLNLIHPGRIQVFGHQETEYYQRLSNT 74 +E L L G ER L S + + G + R+Q+FG E + + + Sbjct: 11 KERLNLELICSETGLERPILTSDLSRPGLELTGFFSYYPEDRVQLFGMTEISFSEGMEPE 70 Query: 75 SRAYQTAELVAGEPPAFIIAQGLATPPDILAICDEKNIPLFSTPLPAAQVIDYLRVYLSK 134 R + ++ PAF+I++ L P +++A E +IP+ + L ++ Y+ YL Sbjct: 71 ERLKRYKQMCTKRTPAFVISRNLEVPKELVAAAKEADIPVLRSRLKTTRLSVYITNYLES 130 Query: 135 KLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADDAVEFARIAPNMI 194 +LA I+MHGV +D+ G+GVLITG SG+GKSE LEL+ R H LVADD VE + + Sbjct: 131 RLAPVISMHGVLVDIYGLGVLITGSSGVGKSETALELVKRGHRLVADDNVEIRQEDEMTL 190 Query: 195 EGRCPPLLQNLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVRRSTLEENYERLPLDA 254 G P ++++LLE+RGLG++++ +FG AVR ++ ++VHL +++Y+R+ LD Sbjct: 191 IGSSPAIIEHLLEIRGLGIINVMTLFGAGAVRSSKKITIVVHLENWDP-DKHYDRVGLDQ 249 Query: 255 QFEDVLAKGLP 265 + + +P Sbjct: 250 EKTKIFDMDIP 260