BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0022.p (408 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0805 [GEPR] COG0477 Permeases of the major facilitator superf... 366 e-101 YPO1504 [GEPR] COG0477 Permeases of the major facilitator superf... 174 5e-43 PA1412 [GEPR] COG0477 Permeases of the major facilitator superfa... 149 8e-36 mlr7399 [GEPR] COG0477 Permeases of the major facilitator superf... 139 9e-33 SMb21000 [GEPR] COG0477 Permeases of the major facilitator super... 135 2e-31 >RSc0805 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 409 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 221/369 (59%), Positives = 263/369 (71%), Gaps = 10/369 (2%) Query: 10 QANRKTALRIALSGLIALSVAMGIGRFAFTPLLPMMLHDQTIDLNSGGWLATSNYLGYFI 69 A R A R+A++G++ALSVAMGIGRFAFTP+LPMMLHD ++ L G WLAT NYLGYF+ Sbjct: 19 HATRTAAWRVAIAGMVALSVAMGIGRFAFTPILPMMLHDGSVTLGQGSWLATLNYLGYFV 78 Query: 70 GALLCAFWRGLPPTRTIRAGLLAAVLLTAGMGAFHSQGLWLLLRLLSGIASALVFVYSSG 129 GAL C RG R IR GL+A VLLTAGMG Q WL+LR +G+ SALVFV+++G Sbjct: 79 GALACMALRG-DAARLIRIGLVATVLLTAGMGVLQGQPAWLVLRFAAGVVSALVFVFTAG 137 Query: 130 WCLQRLAQLQLPALGGIIYSGPGLGIMLTGLSSSAMVAGGWHAAAGWMAFGLMAALLTLL 189 WCL RL +L ALGGII+ GPGLGI + GL +S MVA GWHA++ W+AFG+++A+L+ Sbjct: 138 WCLHRLTELGHAALGGIIFCGPGLGIAVPGLVASGMVALGWHASSAWIAFGVLSAVLSAA 197 Query: 190 VWKTFRGEVDLRAGAAATG--SADQGYTEPAPVTREVRWQVLAYGLAGFGYIITATFLPV 247 VW T R E A A+A G A G P + LAYGLAGFGYI+TATFLPV Sbjct: 198 VWPTVRPERRPHAAASAPGISGAAPGLGLPTVII------TLAYGLAGFGYIVTATFLPV 251 Query: 248 IARQALP-GSSWPDFFWPLFGLCVALGALGATRIPVHADQRRLLAISYVMQAIGVIISAI 306 IAR+ LP GS WPD FWP+FG+ VALGAL +TRI + D R LLA +Y MQA+ V S + Sbjct: 252 IARRVLPAGSIWPDLFWPIFGVGVALGALLSTRISLARDNRTLLAAAYAMQAVAVAASIV 311 Query: 307 LPNEFGFALGSILLGLPFTAITLFAMREARRLRSHHAPGLMGLMTASYGIGQIAGPPLAT 366 P G AL S+LLGLPFTAITLFAMREARRL H P LMGLMTA YGIGQIAGPPLA Sbjct: 312 WPTVGGLALSSLLLGLPFTAITLFAMREARRLWPHAVPRLMGLMTAVYGIGQIAGPPLAN 371 Query: 367 KLVHVSGSF 375 +L +G F Sbjct: 372 RLFAATGGF 380 >YPO1504 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 383 Score = 174 bits (440), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 136/391 (34%), Positives = 200/391 (51%), Gaps = 15/391 (3%) Query: 16 ALRIALSGLIALSVAMGIGRFAFTPLLPMMLHDQTIDLNSGGWLATSNYLGYFIGALLCA 75 ALR+ALSG +AL VAMGIGRFAFTP +P+M+ + L S G +A NYLGY GA A Sbjct: 2 ALRVALSGFLALVVAMGIGRFAFTPQVPLMIAEHQFTLTSAGLVAAFNYLGYLFGA-FDA 60 Query: 76 FWRGLPPTRTIRAGLLAAVLLTAGMGAFHSQGLWL-LLRLLSGIASALVFVYSSGWCLQR 134 R + GL A LLT + A W L+R G AS V + W +R Sbjct: 61 MRASRHVERRLWLGLWGAALLTL-LSAVVVGPWWHGLVRFAIGWASGWSMVLIAAWTNER 119 Query: 135 LAQLQLPALGGIIYSGPGLGIMLTGLSSSAMVAGGWHAAAGWMAFGLMAALLTLLVWKTF 194 LA PAL +++GPG GI ++G+ + A+ + AA W +G++A ++ + Sbjct: 120 LAHFGRPALSAAVFAGPGAGIFISGMLAVAIHSYDLSAAEAWWVYGVLALVIIASI---- 175 Query: 195 RGEVDLRAGAAATGSADQGYTEPAPVTREVRWQVLAYGLAGFGYIITATFLPVIARQALP 254 ++L G Q P +T ++ V +Y LAGFGYI+ ATFL +A P Sbjct: 176 --SINLPRGGEL--HRPQVVAVPLTLTPALKRLVWSYSLAGFGYILPATFLSQMASARFP 231 Query: 255 GSSWPDFFWPLFGLCVALG-ALGATRIPVHADQRRLLAISYVMQAIGVIISAILPNEFGF 313 S + F WP+FG +G ALG Q R LA++ +QA+GV+ + +P G Sbjct: 232 DSLFAQFVWPVFGGAAVIGIALGILTRHCLTSQTR-LALTLWVQALGVLCAEWVPGVSGL 290 Query: 314 ALGSILLGLPFTAITLFAMREARRLRSHHAPGLMGLMTASYGIGQIAGPPLATKLVHVSG 373 ALG++L G F ++ +++ R L H + GL+T Y IGQ+ GP L+ ++ Sbjct: 291 ALGALLTGGGFLSVVQLSLQHGRELAPEHTRYMAGLLTTGYAIGQLVGPILSAISTTLTH 350 Query: 374 SFTPSLSIAAATLLAGAGVYGWLATRDRTGK 404 P+L +A L+ G+ + T RT + Sbjct: 351 RLEPALYVAVVALIIAGGLV--IKTPARTQE 379 >PA1412 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 397 Score = 149 bits (377), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 129/356 (36%), Positives = 183/356 (51%), Gaps = 15/356 (4%) Query: 31 MGIGRFAFTPLLPMMLHDQTIDLNSGGWLATSNYLGYFIGALLCAFWRGLPPTR-TIRAG 89 MG+GRF+ TP LP ++ + +DL G LA +NYLGY +GAL F R R + G Sbjct: 24 MGVGRFSLTPQLPHLIREGQLDLTGAGLLAAANYLGYLVGALDALFAREARQARLRLLVG 83 Query: 90 LLAAVLLTAGMGAFHSQGLW--LLLRLLSGIASALVFVYSSGWCLQRLAQLQLPALGGII 147 L A LT + + ++G W LLR G+ASA V + + + A+ LG ++ Sbjct: 84 LWACFGLT--LASVWAEGFWPHALLRFGLGVASAWVLIMVTALSQRLAAESGRARLGALV 141 Query: 148 YSGPGLGIMLTGLSSSAMVAGGWHAAAGWMAFGLMAALLTLLVWKTFRGEVDLRAGAAAT 207 ++GPG+G+M+TGL ++ A G + W F +A +L L++ AG A Sbjct: 142 FAGPGIGVMVTGLLAALGNALGQDSVFIWKLFADLALVLILMLLPLLPRPAARGAGHDAP 201 Query: 208 GSADQGYTEPAPVTREVRWQVLAYGLAGFGYIITATFLPVIARQALPGSSWPDFFWPLFG 267 +A +E A + R + W AYGL G GYII ATFL +A G D FWP FG Sbjct: 202 ATA----SENAGLGR-LTW---AYGLVGLGYIIPATFLSQMAAARFHGQWQADLFWPCFG 253 Query: 268 LCVALG-ALGATRIPVHADQRRLLAISYVMQAIGVIISAILPNEFGFALGSILLGLPFTA 326 L A G L + R RR L + +QA+GV ++ +LP G ALG +L GLPF A Sbjct: 254 LASATGVVLISLRRQRPDGTRRWLVGALWLQALGV-LACLLPGIGGLALGVVLTGLPFLA 312 Query: 327 ITLFAMREARRLRSHHAPGLMGLMTASYGIGQIAGPPLATKLVHVSGSFTPSLSIA 382 M+ AR L H G +T + +GQ+ GP LA H +G P+L++A Sbjct: 313 GMQLVMQYARELAPHTPQRNAGQLTTGFALGQLLGPLLAALSTHFAGGLQPALALA 368 >mlr7399 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 401 Score = 139 bits (351), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 136/392 (34%), Positives = 199/392 (50%), Gaps = 16/392 (4%) Query: 10 QANRKTALRIALSGLIALSVAMGIGRFAFTPLLPMMLHDQTIDLNSGGWLATSNYLGYFI 69 ++ TALR +++G+IA++VAMGIGRF +TP+LP M+ + + + GW+A++NYLGY + Sbjct: 17 RSATSTALRFSVAGMIAMAVAMGIGRFVYTPILPGMMEELHLSPANAGWIASANYLGYLV 76 Query: 70 GALLCAFWRGLPPTRTIR-AGLLAAVLLTAGMGAFHSQGLWLLLRLLSGIASALVFVYSS 128 GA A R + GL A+ +L A MG + +LL+R L+G+ASA V V+ + Sbjct: 77 GAFAAAGGWAHGRERLLMLGGLGASTILAALMGLTDAMAAFLLIRFLAGLASAFVMVFMA 136 Query: 129 GWCLQRLAQLQLPALGGIIYSGPGLGIMLTGLSSSAMVA--GGWHAAAGWMAFGLMAALL 186 + L + G GLGI ++ + + +V GW AAGW+ ++A Sbjct: 137 SIVFSHINAAGRGDLQAWHFGGVGLGIAISAVMMAVLVTEHAGW--AAGWLWSAAISA-C 193 Query: 187 TLLVWKTFRGEVDLRAGAAATGSADQGYTEPA-PVTREVRWQVLAYGLAGFGYIITATFL 245 +V E L G Q EPA P R + ++AYGL GFGY++TATFL Sbjct: 194 GFVVVALLANEGPLANG--------QAVREPALPKDRSLTKIIIAYGLFGFGYVVTATFL 245 Query: 246 PVIARQALPGSSWPDFFWPLFGLCVALGALGATRIPVHADQRRLLAISYVMQAIGVIISA 305 I RQ + W + GL +I A++ +++ IGV S Sbjct: 246 VAIVRQGGGSRVFEAMVWLVAGLAGFPSTWLWQKIAGRVGLNAAYALACLIEVIGVTASV 305 Query: 306 ILPNEFGFALGSILLGLPFTAITLFAMREARRLRSHHAPGLMGLMTASYGIGQIAGPPLA 365 L G LG +LLG F AIT ++ AR+ + LMTAS+G+GQI GP A Sbjct: 306 ALGGYSGPLLGGLLLGGTFIAITALGLQAARQQAPQAPRRIFALMTASFGLGQIIGPIAA 365 Query: 366 TKLVHVSGSFTPSLSIAAATLLAGAGVYGWLA 397 L +SG F + SI AA +L +GV W A Sbjct: 366 GLLAQMSGDFFLA-SIVAAAMLVVSGVITWSA 396 >SMb21000 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 377 Score = 135 bits (340), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 122/386 (31%), Positives = 195/386 (50%), Gaps = 21/386 (5%) Query: 27 LSVAMGIGRFAFTPLLPMMLHDQTIDLNSGGWLATSNYLGYFIGALLCAFWRGLPPTRTI 86 ++VAMG GRF++TP+LP M+ D + G +A++N++GY GA+L + R + Sbjct: 1 MAVAMGFGRFSYTPILPAMMTDTGLSPADAGLVASANFIGYLAGAVLAGYRWAHGRERGV 60 Query: 87 -RAGLLAAVLLTAGMGAFHSQGLWLLLRLLSGIASALVFVYSSGWCLQRLAQLQLPALGG 145 A L+A LL A MG S + ++R L+G+ASA ++ SG L + + + Sbjct: 61 GLAALVATTLLLAAMGLTSSVLAYSIIRFLAGLASAFAMIFISGIVLGQGLAARSEHVPS 120 Query: 146 IIYSGPGLGIMLTGLS----SSAMVAGGWHAAAGWMAFGLMAALLTLLVWKTFRGEVDLR 201 + + G G GI L+ ++ A VAG + A W L+A T+LV Sbjct: 121 VHFGGVGFGIALSSIAVWVAPLAGVAGLSMSQADWFVGALVALAGTVLVAALL------- 173 Query: 202 AGAAATGSADQGYTE-PAPVTREVRWQVLAYGLAGFGYIITATFLPVIARQALPGSSWPD 260 A+ +A+ G E P +R + L YG GFGY+ITATFL +AR A G S Sbjct: 174 --PASRHAANGGRPEVPLVRSRPLMAMTLTYGFFGFGYVITATFLVAMARDASGGHSVEF 231 Query: 261 FFWPLFGLCVALGA-LGATRIPVHADQRRLLAISYVMQAIGVIISAILPNEFGFALGSIL 319 W + G+ AL L +P + AI +++A+G++++ LP+ + +G ++ Sbjct: 232 LAWLITGVSAALSVYLWRFAVP-RFGLAGVYAIGLLVEAVGLVLTVSLPSPYAPLVGGLM 290 Query: 320 LGLPFTAITLFAMREARRLRSHHAPGLMGLMTASYGIGQIAGPPLATKLVHVSGSFT-PS 378 LG F +T + ++ R+L + MTA++GIGQI GP +A L +GS+ P+ Sbjct: 291 LGATFMMVTAYGLQIGRQLAPESPRRALAFMTAAFGIGQIVGPLVAGWLAERTGSYALPT 350 Query: 379 LSIAAATLLAGAGVYGWLATRDRTGK 404 L A ++ G V LA RT + Sbjct: 351 LVAAVVLMICGIVV---LAELRRTNE 373