BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0127.p (378 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 348 2e-95 SMa2213 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Si... 348 2e-95 BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 338 1e-92 SPAC9E9.09c [C] COG1012 NAD-dependent aldehyde dehydrogenases Sp... 330 3e-90 YER073w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Sa... 327 2e-89 >BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 498 Score = 348 bits (892), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 170/364 (46%), Positives = 224/364 (61%) Query: 2 FEYYAGWTDKFYGDVIPVPSSHLNYTRREPVGAVLQITPWNAPIFTCGWQVAPAIAMGNA 61 F Y+AGW K G IPV + NYTR E +G V QI PWN P+ W++ A+A G Sbjct: 132 FRYFAGWATKIVGQTIPVQGHYFNYTRHEAIGVVGQIIPWNFPLLMAAWKLGAALATGCT 191 Query: 62 VLLKPSELTPFTSLAVAALAEQAGVPKGLINVLAGQGHTVGQAAIDHRVVKKVVFVGSPQ 121 V+LKP+E TP ++L + L +AG PKG++N++ G GH+ G ++H V KV F GS Sbjct: 192 VVLKPAEQTPLSALYLGELINEAGFPKGVVNIVPGFGHSAGTPLVNHPAVDKVAFTGSTD 251 Query: 122 TGKKIAEAAARRLLPCVLELGGKSANIVFADADLKRACLGAQAAIFSSAGQSCVAGSRLL 181 GK I + A+ L LELGGKS NI+ DADL +A G+ I + GQ C AGSRL Sbjct: 252 VGKLIMKQASESLKRVTLELGGKSPNIILPDADLSKAVPGSLMGIMFNQGQVCCAGSRLY 311 Query: 182 VQRSVYEEFVAMLANGASKIKVGQPLDAQTEVGPISNRKQYEHVRGMIAEGVRNGARLAT 241 VQ+ Y+ VA L + ++I+ G L QT +GP+ + +Q V+ I GV GA L T Sbjct: 312 VQKKQYDHVVADLVSLTNEIQQGDGLLEQTTMGPLISNQQQSRVKNYIDRGVEEGAELLT 371 Query: 242 VAQDFSTPGFFVRPTVLADVSNDMAVAQQEIFGPVVAAIPFDTEEDAVRIANDSDFGLAG 301 G+FV PT+ ADV + M +A++EIFGPVVAA+PFD+ +D + ANDSD+GLA Sbjct: 372 GGNIPYDQGYFVAPTIFADVDHSMTIAKEEIFGPVVAAMPFDSIDDLIDKANDSDYGLAA 431 Query: 302 AVWTNDVARAHRVAASINAGTFWINGYKTINVTSPFGGYGQSGYGRSSGVEALYEYTQTK 361 VWT D+ +AH +A I AGT W+N Y + SPFGGY QSG GR G AL YT+ K Sbjct: 432 GVWTQDIKKAHYIAHRIKAGTIWVNCYNVFDAASPFGGYKQSGIGREMGSYALENYTEVK 491 Query: 362 SVWV 365 SVWV Sbjct: 492 SVWV 495 >SMa2213 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 494 Score = 348 bits (892), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 170/378 (44%), Positives = 242/378 (64%), Gaps = 4/378 (1%) Query: 2 FEYYAGWTDKFYGDVIPVPSSHLNYTRREPVGAVLQITPWNAPIFTCGWQVAPAIAMGNA 61 + YYAG+ DK G + P L+++R EP+G + I PWNAP+ + APA+A GN Sbjct: 114 YHYYAGFADKIEGTLHPCDKPALSFSRHEPLGVCVGIVPWNAPLLLFSLKAAPALAAGNT 173 Query: 62 VLLKPSELTPFTSLAVAALAEQAGVPKGLINVLAGQGHTVGQAAIDHRVVKKVVFVGSPQ 121 +++KP+E T T+L + L E+AG P G+INV+ G G VG+ + H + + V F GS + Sbjct: 174 LVMKPAEFTSATALKLMELVEKAGFPTGVINVVTGYGPEVGEPLVTHPLTRHVGFTGSTK 233 Query: 122 TGKKIAEAAARRLLPCVLELGGKSANIVFADADLKRACLGAQAAIFSSAGQSCVAGSRLL 181 TG + AA+ + LELGGKS NIVF DADL A G IF + GQ+C+AGSRLL Sbjct: 234 TGAHLYSLAAKDVKRVSLELGGKSPNIVFGDADLDNAVRGVVGGIFGAVGQTCIAGSRLL 293 Query: 182 VQRSVYEEFVAMLANGASKIKVGQPLDAQTEVGPISNRKQYEHVRGMIAEGVRNGARL-- 239 V RS+++EF+ LA ++G P +T++GPI+N Q+E V G I R GA L Sbjct: 294 VHRSIHDEFLEKLAVFTKTARIGDPRKVETQIGPIANSMQFEKVLGYIDIARREGAELIL 353 Query: 240 --ATVAQDFSTPGFFVRPTVLADVSNDMAVAQQEIFGPVVAAIPFDTEEDAVRIANDSDF 297 + G+F+ PT+ A VSNDM +A++E+FGPV++AI FD E+A+ IANDS+F Sbjct: 354 GGGRPDLEECGTGYFIEPTIFAGVSNDMRIAREEVFGPVLSAIVFDEPEEALAIANDSEF 413 Query: 298 GLAGAVWTNDVARAHRVAASINAGTFWINGYKTINVTSPFGGYGQSGYGRSSGVEALYEY 357 GL VWT+D+ A +++ + AG+ W+N Y+ I+ T+PFGGY +SG GR +GV +YEY Sbjct: 414 GLGAGVWTSDMRLALKMSERLEAGSVWVNTYRDISYTTPFGGYKKSGIGRENGVAGIYEY 473 Query: 358 TQTKSVWVETAKEPAAAF 375 QTK+VW+ TA+E A F Sbjct: 474 LQTKAVWLSTAEEIANPF 491 >BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 495 Score = 338 bits (867), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 161/364 (44%), Positives = 228/364 (62%) Query: 2 FEYYAGWTDKFYGDVIPVPSSHLNYTRREPVGAVLQITPWNAPIFTCGWQVAPAIAMGNA 61 YYAGW K G IPV ++ NYTR EPVG V QI PWN P+ W++ A+A G Sbjct: 128 MRYYAGWCTKITGQTIPVSGAYFNYTRHEPVGVVGQIIPWNFPLLMAMWKMGAALATGCT 187 Query: 62 VLLKPSELTPFTSLAVAALAEQAGVPKGLINVLAGQGHTVGQAAIDHRVVKKVVFVGSPQ 121 ++LKP+E TP ++L +A L +QAG P G+IN++ G G G+A +H V K+ F GS + Sbjct: 188 IVLKPAEQTPLSALYLAELIDQAGFPAGVINIIPGFGEDAGEALTNHEAVDKIAFTGSTE 247 Query: 122 TGKKIAEAAARRLLPCVLELGGKSANIVFADADLKRACLGAQAAIFSSAGQSCVAGSRLL 181 GKKI AA+ + LELGGKS NI+ DA+LK+A GA + + GQ C AGSR+ Sbjct: 248 IGKKIMSTAAKSIKRVTLELGGKSPNILLPDANLKKAIPGALNGVMFNQGQVCCAGSRVF 307 Query: 182 VQRSVYEEFVAMLANGASKIKVGQPLDAQTEVGPISNRKQYEHVRGMIAEGVRNGARLAT 241 + + Y+E V +A+ A ++ G L T++GP+ +++Q+E V I +G GA+ T Sbjct: 308 IHKDQYDEVVDEMASYAESLRQGAGLHKDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVT 367 Query: 242 VAQDFSTPGFFVRPTVLADVSNDMAVAQQEIFGPVVAAIPFDTEEDAVRIANDSDFGLAG 301 G+FV PTV A+V ++M +A++EIFGPV+ AIP++T ++ + AN S++GLA Sbjct: 368 GGSCPFEAGYFVAPTVFANVEDEMTIAKEEIFGPVLTAIPYETVDEVIERANHSEYGLAA 427 Query: 302 AVWTNDVARAHRVAASINAGTFWINGYKTINVTSPFGGYGQSGYGRSSGVEALYEYTQTK 361 +WT +V +AH +A + AGT W+N Y + SPFGGY QSG GR G AL YT+ K Sbjct: 428 GLWTENVKQAHYIADRLQAGTVWVNCYNVFDAASPFGGYKQSGLGREMGSYALDNYTEVK 487 Query: 362 SVWV 365 SVWV Sbjct: 488 SVWV 491 >SPAC9E9.09c [C] COG1012 NAD-dependent aldehyde dehydrogenases Spo Schizosaccharomyces pombe Length = 503 Score = 330 bits (847), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 163/365 (44%), Positives = 219/365 (60%), Gaps = 1/365 (0%) Query: 2 FEYYAGWTDKFYGDVIPVPSSHLNYTRREPVGAVLQITPWNAPIFTCGWQVAPAIAMGNA 61 F YY GW DK YG I YTR EP+G QI PWN P C W++APA+A GN Sbjct: 131 FRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNT 190 Query: 62 VLLKPSELTPFTSLAVAALAEQAGVPKGLINVLAGQGHTVGQAAIDHRVVKKVVFVGSPQ 121 ++LK +ELTP ++L + + G P G+INVL+G G G A H + KV F GS Sbjct: 191 IILKTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGSTG 250 Query: 122 TGKKIAEAAARRLLPCV-LELGGKSANIVFADADLKRACLGAQAAIFSSAGQSCVAGSRL 180 G+ + AAA L V LELGGKS NIVF DADL A + IF ++GQ C AGSR+ Sbjct: 251 VGRMVMRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGSRV 310 Query: 181 LVQRSVYEEFVAMLANGASKIKVGQPLDAQTEVGPISNRKQYEHVRGMIAEGVRNGARLA 240 VQ VY+EF+ + A +KVG P T G +++QYE + I G+ +GA+L Sbjct: 311 YVQEDVYDEFIKRMVAKAKTLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAKLE 370 Query: 241 TVAQDFSTPGFFVRPTVLADVSNDMAVAQQEIFGPVVAAIPFDTEEDAVRIANDSDFGLA 300 + G+FV PT+L++V+ DMAV ++EIFGPV+A I F T E+A+R N+S +GLA Sbjct: 371 IGGKRHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYGLA 430 Query: 301 GAVWTNDVARAHRVAASINAGTFWINGYKTINVTSPFGGYGQSGYGRSSGVEALYEYTQT 360 V TN++ A +V+ ++ AGT W+N Y ++ PFGGY +SG GR G L YTQT Sbjct: 431 AGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYTQT 490 Query: 361 KSVWV 365 K+V + Sbjct: 491 KAVHI 495 >YER073w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Saccharomyces cerevisiae Length = 520 Score = 327 bits (839), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 158/363 (43%), Positives = 219/363 (60%) Query: 7 GWTDKFYGDVIPVPSSHLNYTRREPVGAVLQITPWNAPIFTCGWQVAPAIAMGNAVLLKP 66 GW DK YG+VI +H Y+ +EP+G QI PWN P+ W++ PA+A GN V+LKP Sbjct: 155 GWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKP 214 Query: 67 SELTPFTSLAVAALAEQAGVPKGLINVLAGQGHTVGQAAIDHRVVKKVVFVGSPQTGKKI 126 +E TP ++L + L ++AG+P G++N+L G G VG+ H VKK+ F GS TG+ I Sbjct: 215 AETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHI 274 Query: 127 AEAAARRLLPCVLELGGKSANIVFADADLKRACLGAQAAIFSSAGQSCVAGSRLLVQRSV 186 + AA + LELGGKS NIVFADADL +A IF ++G+ C AGSR+ +Q +V Sbjct: 275 MKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTV 334 Query: 187 YEEFVAMLANGASKIKVGQPLDAQTEVGPISNRKQYEHVRGMIAEGVRNGARLATVAQDF 246 YEE + L + +KVG P D + G ++ KQ + + GARL T Sbjct: 335 YEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARH 394 Query: 247 STPGFFVRPTVLADVSNDMAVAQQEIFGPVVAAIPFDTEEDAVRIANDSDFGLAGAVWTN 306 + G+FV+PTV ADV DM + ++E+FGP+V F T ++ + +ANDS +GLA + TN Sbjct: 395 GSKGYFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTN 454 Query: 307 DVARAHRVAASINAGTFWINGYKTINVTSPFGGYGQSGYGRSSGVEALYEYTQTKSVWVE 366 D+ +A V+ + AGT WIN Y + PFGG+GQSG GR G AL YTQTKSV + Sbjct: 455 DINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIA 514 Query: 367 TAK 369 K Sbjct: 515 IDK 517