BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0030.0103.p         (179 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA1686 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine ...   152   3e-37
ZalkA [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine D...    99   5e-21
ECs2877 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine...    99   5e-21
alkA [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DN...    98   7e-21
Rv1317c_2 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguani...    95   6e-20

>PA1686 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA
           glycosylase Pae Pseudomonas aeruginosa
          Length = 297

 Score =  152 bits (385), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 88/171 (51%), Positives = 114/171 (66%), Gaps = 9/171 (5%)

Query: 1   VRTIVGQQVSVKAATTIVGRLVERAGERIEGHPHAATAWRFPTPHALATVDLAAIGMPGK 60
           VR IVGQQV+VKAA TI GRL++R GE +E   +   +  FPTP ALA  +L  IGMPGK
Sbjct: 132 VRAIVGQQVTVKAAVTITGRLIQRLGEPLEDLGYDGISHLFPTPAALAQANLDGIGMPGK 191

Query: 61  RVAALQGFAHAVAQGDVPVDDPAADTAD-LRKALLGLPGIGPWTVEYVAMRAWRDARCGD 119
           RV  LQ FA A+A G++ +D   AD  + L + L  LPGIGPWT EY+A+RA      G+
Sbjct: 192 RVQTLQRFAAAIASGELSLD--LADGPEALVERLCALPGIGPWTAEYIALRA-----MGE 244

Query: 120 ADAWPASDLVLMQAIIDRDPSLLKLTHQKSRAETWRPWRAYVAMHLWNEIA 170
           ADA+PA+DL L+++ +   P  +     K+RAE WRPWRAY A+HLW+  A
Sbjct: 245 ADAFPAADLGLLKSTV-WGPQGIDARSLKARAEAWRPWRAYAAIHLWHHYA 294


>ZalkA [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA
           glycosylase EcZ Escherichia coli O157:H7 EDL933
          Length = 282

 Score = 99.0 bits (245), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 61/169 (36%), Positives = 85/169 (50%), Gaps = 17/169 (10%)

Query: 1   VRTIVGQQVSVKAATTIVGRLVERAGERIEGHPHAATAWRFPTPHALATVD---LAAIGM 57
           VR I+GQ VSV  A  +  ++V+  GER++  P       FPTP  LA  D   L A+GM
Sbjct: 118 VRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYIC---FPTPQRLAAADPQALKALGM 174

Query: 58  PGKRVAALQGFAHAVAQGDVPVDDPAADTADLRKALLGLPGIGPWTVEYVAMRAWRDARC 117
           P KR  AL   A+A  +G +P+  P  D     K L   PGIG WT  Y A+R W+    
Sbjct: 175 PLKRAEALIHLANAALEGTLPMTIPG-DVEQAMKTLQTFPGIGRWTANYFALRGWQ---- 229

Query: 118 GDADAWPASDLVLMQAIIDRDPSLLKLTHQKSRAETWRPWRAYVAMHLW 166
              D +   D ++ Q      P+ +     +  AE W+PWR+Y  +H+W
Sbjct: 230 -AKDVFLPDDYLIKQRFPGMTPAQI-----RRYAERWKPWRSYALLHIW 272


>ECs2877 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA
           glycosylase Ecs Escherichia coli O157:H7
          Length = 282

 Score = 99.0 bits (245), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 61/169 (36%), Positives = 85/169 (50%), Gaps = 17/169 (10%)

Query: 1   VRTIVGQQVSVKAATTIVGRLVERAGERIEGHPHAATAWRFPTPHALATVD---LAAIGM 57
           VR I+GQ VSV  A  +  ++V+  GER++  P       FPTP  LA  D   L A+GM
Sbjct: 118 VRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYIC---FPTPQRLAAADPQALKALGM 174

Query: 58  PGKRVAALQGFAHAVAQGDVPVDDPAADTADLRKALLGLPGIGPWTVEYVAMRAWRDARC 117
           P KR  AL   A+A  +G +P+  P  D     K L   PGIG WT  Y A+R W+    
Sbjct: 175 PLKRAEALIHLANAALEGTLPMTIPG-DVEQAMKTLQTFPGIGRWTANYFALRGWQ---- 229

Query: 118 GDADAWPASDLVLMQAIIDRDPSLLKLTHQKSRAETWRPWRAYVAMHLW 166
              D +   D ++ Q      P+ +     +  AE W+PWR+Y  +H+W
Sbjct: 230 -AKDVFLPDDYLIKQRFPGMTPAQI-----RRYAERWKPWRSYALLHIW 272


>alkA [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA
           glycosylase Eco Escherichia coli K12
          Length = 282

 Score = 98.2 bits (243), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 61/169 (36%), Positives = 84/169 (49%), Gaps = 17/169 (10%)

Query: 1   VRTIVGQQVSVKAATTIVGRLVERAGERIEGHPHAATAWRFPTPHALATVD---LAAIGM 57
           VR I+GQ VSV  A  +  R+ +  GER++  P       FPTP  LA  D   L A+GM
Sbjct: 118 VRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYIC---FPTPQRLAAADPQALKALGM 174

Query: 58  PGKRVAALQGFAHAVAQGDVPVDDPAADTADLRKALLGLPGIGPWTVEYVAMRAWRDARC 117
           P KR  AL   A+A  +G +P+  P  D     K L   PGIG WT  Y A+R W+    
Sbjct: 175 PLKRAEALIHLANAALEGTLPMTIPG-DVEQAMKTLQTFPGIGRWTANYFALRGWQ---- 229

Query: 118 GDADAWPASDLVLMQAIIDRDPSLLKLTHQKSRAETWRPWRAYVAMHLW 166
              D +   D ++ Q      P+ +     +  AE W+PWR+Y  +H+W
Sbjct: 230 -AKDVFLPDDYLIKQRFPGMTPAQI-----RRYAERWKPWRSYALLHIW 272


>Rv1317c_2 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA
           glycosylase Mtu Mycobacterium tuberculosis H37Rv
          Length = 317

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 69/180 (38%), Positives = 88/180 (48%), Gaps = 18/180 (10%)

Query: 1   VRTIVGQQVSVKAATTIVGRLVERAGERIEGHPHAATAWRFPTPHALATVDLAAIGMPGK 60
           VR ++ QQVS KAA+T  GRLV   G  +    H A    FP+   LA +D   + +P  
Sbjct: 143 VRAVLAQQVSTKAASTHAGRLVAAYGRPVHDR-HGALTHTFPSIEQLAEIDPGHLAVPKA 201

Query: 61  RVAALQGFAHAVAQGDVPVDDPAADTADLRKALLGLPGIGPWTVEYVAMRAWRDARCGDA 120
           R   +     ++A   + V D   D    R  LL LPG+GPWT E +AMR       GD 
Sbjct: 202 RQRTINALVASLADKSL-VLDAGCDWQRARGQLLALPGVGPWTAEVIAMRG-----LGDP 255

Query: 121 DAWPASDLVLMQAIIDRDPSLLKLTHQKSRAET-----WRPWRAYVAMHLWNEIADRMGQ 175
           DA+PASDL L  A        L L  Q+ RA T     WRPWR+Y   HLW  +   + Q
Sbjct: 256 DAFPASDLGLRLAA-----KKLGLPAQR-RALTVHSARWRPWRSYATQHLWTTLEHPVNQ 309