BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0094.p (243 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0901 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 426 e-119 NMA1599 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 373 e-103 NMB1384 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 372 e-103 PA3168 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, t... 372 e-103 YPO1216 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 362 e-100 >RSc0901 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Rso Ralstonia solanacearum Length = 885 Score = 426 bits (1095), Expect = e-119, Method: Compositional matrix adjust. Identities = 195/239 (81%), Positives = 219/239 (91%) Query: 1 MDQFAKETIPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVWN 60 MDQFAKET+P+SLEEEMR SYL YAMSVIVGRALPDVRDGLKPVHRRVL+AMHE+NN WN Sbjct: 1 MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWN 60 Query: 61 RPFVKCARVVGEVMGKYHPHGDASIYDTLVRMAQDFSLRYMLVDGQGNFGSIDGDGAAAM 120 RP+ K AR+VG+V+GKYHPHGD+++YDT+VRMAQDFSLRYMLVDGQGNFGS+DGD AAAM Sbjct: 61 RPYKKSARIVGDVIGKYHPHGDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAM 120 Query: 121 RYTECRLDKIANELLADIEKETVDFDPNYDGKEKEPSVLPTRIPNLLINGSSGIAVGMAT 180 RYTE RL KIA+ELLADI+KETVDF+PNYDG E EPS+LP RIPNLLINGSSGIAVGMAT Sbjct: 121 RYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILPARIPNLLINGSSGIAVGMAT 180 Query: 181 NIPPHNITEVINGALHVLSNADCTIDELIELIPAPDFPTGGIIYGVSGVRDGYRIGDAR 239 NIPPHN+ EV++G LH+L N D T+DELIELIPAPDFPT GIIYG+SGVR+GYR G R Sbjct: 181 NIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGR 239 >NMA1599 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit NmA Neisseria meningitidis Z2491 Length = 916 Score = 373 bits (957), Expect = e-103, Method: Compositional matrix adjust. Identities = 168/237 (70%), Positives = 204/237 (86%) Query: 3 QFAKETIPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVWNRP 62 +FA ET+P+SLE+EMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVL+AMHE+ N WN Sbjct: 11 KFALETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAA 70 Query: 63 FVKCARVVGEVMGKYHPHGDASIYDTLVRMAQDFSLRYMLVDGQGNFGSIDGDGAAAMRY 122 + K AR+VG+V+GKYHPHGD ++YDT+VRMAQ+F++RY+L+DGQGNFGS+DG AAAMRY Sbjct: 71 YKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRY 130 Query: 123 TECRLDKIANELLADIEKETVDFDPNYDGKEKEPSVLPTRIPNLLINGSSGIAVGMATNI 182 TE R+ KI++E+LADIE+ETV+F PNYDG E EP VLPTR P LL+NGSSGIAVGMATNI Sbjct: 131 TEIRMAKISHEMLADIEEETVNFGPNYDGSEHEPLVLPTRFPTLLVNGSSGIAVGMATNI 190 Query: 183 PPHNITEVINGALHVLSNADCTIDELIELIPAPDFPTGGIIYGVSGVRDGYRIGDAR 239 PPHN+++ +N L +L D IDELI++I APDFPTG IYG+SGVR+GY+ G R Sbjct: 191 PPHNLSDTVNACLRLLDAPDTEIDELIDIIQAPDFPTGATIYGLSGVREGYKTGRGR 247 >NMB1384 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Nme Neisseria meningitidis MC58 Length = 916 Score = 372 bits (956), Expect = e-103, Method: Compositional matrix adjust. Identities = 168/237 (70%), Positives = 204/237 (86%) Query: 3 QFAKETIPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVWNRP 62 +FA ET+P+SLE+EMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVL+AMHE+ N WN Sbjct: 11 KFALETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAA 70 Query: 63 FVKCARVVGEVMGKYHPHGDASIYDTLVRMAQDFSLRYMLVDGQGNFGSIDGDGAAAMRY 122 + K AR+VG+V+GKYHPHGD ++YDT+VRMAQ+F++RY+L+DGQGNFGS+DG AAAMRY Sbjct: 71 YKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRY 130 Query: 123 TECRLDKIANELLADIEKETVDFDPNYDGKEKEPSVLPTRIPNLLINGSSGIAVGMATNI 182 TE R+ KI++E+LADIE+ETV+F PNYDG E EP VLPTR P LL+NGSSGIAVGMATNI Sbjct: 131 TEIRMAKISHEMLADIEEETVNFGPNYDGSEHEPLVLPTRFPTLLVNGSSGIAVGMATNI 190 Query: 183 PPHNITEVINGALHVLSNADCTIDELIELIPAPDFPTGGIIYGVSGVRDGYRIGDAR 239 PPHN+++ +N L +L D IDELI++I APDFPTG IYG+SGVR+GY+ G R Sbjct: 191 PPHNLSDTVNACLRLLDAPDTEIDELIDIIQAPDFPTGATIYGLSGVREGYKTGRGR 247 >PA3168 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Pae Pseudomonas aeruginosa Length = 923 Score = 372 bits (954), Expect = e-103, Method: Compositional matrix adjust. Identities = 167/239 (69%), Positives = 206/239 (86%) Query: 1 MDQFAKETIPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVWN 60 M + AKE +P+++E+E+++SYLDYAMSVIVGRALPD RDGLKPVHRRVL+AM E+ N WN Sbjct: 1 MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWN 60 Query: 61 RPFVKCARVVGEVMGKYHPHGDASIYDTLVRMAQDFSLRYMLVDGQGNFGSIDGDGAAAM 120 +P+ K ARVVG+V+GKYHPHGD ++YDT+VRMAQ FSLRYMLVDGQGNFGS+DGD AAAM Sbjct: 61 KPYKKSARVVGDVIGKYHPHGDTAVYDTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAM 120 Query: 121 RYTECRLDKIANELLADIEKETVDFDPNYDGKEKEPSVLPTRIPNLLINGSSGIAVGMAT 180 RYTE R+ K+A+ELLAD+EKETVD+ PNYDG E+ P+V+PT+IPNLL+NGSSGIAVGMAT Sbjct: 121 RYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMPTKIPNLLVNGSSGIAVGMAT 180 Query: 181 NIPPHNITEVINGALHVLSNADCTIDELIELIPAPDFPTGGIIYGVSGVRDGYRIGDAR 239 NIPPHN+ EVI+G L ++ N D T+DEL++ IP PDFPT GII G +G+ + YR G R Sbjct: 181 NIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGR 239 >YPO1216 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Ype Yersinia pestis Length = 891 Score = 362 bits (929), Expect = e-100, Method: Compositional matrix adjust. Identities = 165/239 (69%), Positives = 202/239 (84%) Query: 1 MDQFAKETIPISLEEEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEMNNVWN 60 M A+E P+++EEE++ SYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAM+ + N WN Sbjct: 1 MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWN 60 Query: 61 RPFVKCARVVGEVMGKYHPHGDASIYDTLVRMAQDFSLRYMLVDGQGNFGSIDGDGAAAM 120 +P+ K ARVVG+V+GKYHPHGD+++YDT+VRMAQ FSLRYMLVDGQGNFGS+DGD AAAM Sbjct: 61 KPYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSVDGDSAAAM 120 Query: 121 RYTECRLDKIANELLADIEKETVDFDPNYDGKEKEPSVLPTRIPNLLINGSSGIAVGMAT 180 RYTE R+ KIA+ELLAD+EK+TVDF PNYDG E+ P+V+PTRIPNLL+NGSSGIAVGMAT Sbjct: 121 RYTEIRMSKIAHELLADLEKDTVDFVPNYDGTEQIPAVMPTRIPNLLVNGSSGIAVGMAT 180 Query: 181 NIPPHNITEVINGALHVLSNADCTIDELIELIPAPDFPTGGIIYGVSGVRDGYRIGDAR 239 NIPPHN++EVI+G L + + + +I+ L+E IP PDFPT II G G+ + YR G + Sbjct: 181 NIPPHNLSEVIDGCLAYIEDENISIEGLMEYIPGPDFPTAAIINGRRGIEEAYRTGRGK 239