BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0066.p (329 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 228 2e-59 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 208 1e-53 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 207 2e-53 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 202 9e-52 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 196 6e-50 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 228 bits (580), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 136/335 (40%), Positives = 196/335 (58%), Gaps = 11/335 (3%) Query: 1 MAFVHNETSFYILRFLLGVAEAGFFPGVVYYFTQWLPNSERGKAMAVFLSGSAIASILSG 60 M F + +FY+LRFLLGVAEAGFFPG++ Y T W P R +A+ +F G +A +L G Sbjct: 103 MMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFPQRSRAQALGLFYFGLPLALVLGG 162 Query: 61 PISGALLQIEG-GGLHXWQWMFIIEGLASVLLCFVVWRRLDSRPQDAAWLSDDERNSLAA 119 P+SG LL+ G GL WQW+F+ EGL + L+ + L RP+DA WLSD+++ +L Sbjct: 163 PLSGWLLEFHGIFGLANWQWLFVTEGLLASLVGIAAYFYLVDRPRDAGWLSDEQKRALEG 222 Query: 120 IIAHEQRERQASKPVHVSSWSLLKDPQILLFCFIYFAIQLTIYGATFWLPSIIKKMGHFN 179 +A E +QA P H S L+ Q+L FC +YF IQ+++YG F+LP+ ++ F Sbjct: 223 ELAEEDTRKQARGP-H-GFLSALRSGQVLKFCLVYFTIQMSVYGVVFYLPT---RIASFL 277 Query: 180 DFQVGL----FNSIPWIISIVAMYIFASLAARF-RHQQAWVAATLIIAAAGMFASTTGGP 234 D QVGL +IPW+ ++V + A R +H+Q VA + AA ++ G Sbjct: 278 DGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQHRQLAVAMLGMAAAGIAASALAGNL 337 Query: 235 VFAFVAICFAGIGFKAASSLFWPIPQAYLDARIAAAVIALVNSIGNLGGFFAPATFGYLE 294 A +A CFA GF + LFW +P YL AA+ IAL+NS+GNLGGF AP +E Sbjct: 338 GLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAASGIALINSLGNLGGFVAPNLKTLME 397 Query: 295 QKTGSIQGGLYALAAASVIAAGLVFLARTSGKKAV 329 + + G++ALAA ++ A L+ +TSG +V Sbjct: 398 SQFADPRAGMFALAAVGLLGACLLARLKTSGSSSV 432 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 208 bits (530), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 123/329 (37%), Positives = 180/329 (54%), Gaps = 6/329 (1%) Query: 1 MAFVHNETSFYILRFLLGVAEAGFFPGVVYYFTQWLPNSERGKAMAVFLSGSAIASILSG 60 + F N FY+LRFLLGVAEAGFFPGV+Y T W P + R + + +F+ SA A+ + Sbjct: 101 LGFTQNAAMFYVLRFLLGVAEAGFFPGVLYVLTLWYPQAHRARMVGLFMIASAFANAVGA 160 Query: 61 PISGALLQIEG-GGLHXWQWMFIIEGLASVLLCFVVWRRLDSRPQDAAWLSDDERNSLAA 119 I G LL ++G GL WQW+F++ G +VLL V RL S P DA WL D E++ LA+ Sbjct: 161 AIGGLLLGMDGFLGLAGWQWVFLVTGAPAVLLAPYVLWRLPSGPSDARWLPDVEKSWLAS 220 Query: 120 IIAHEQRERQASKPVHVSSWSLLKDPQILLFCFIYFAIQLTIYGATFWLPSIIKKMGHFN 179 +A ER H +W + DP++L+ +Y + L+ YG ++WLP+I+K G N Sbjct: 221 TLAA---ERGGEVDDHRGAWKAIFDPRVLMLAGLYIGMPLSAYGLSYWLPTIVKSFGVSN 277 Query: 180 DFQVGLFNSIPWIISIVAMYIFASLAARFRHQQAWVAATLIIAAAGMFASTT-GGPVFAF 238 G N IPW++ VA++ AAR +A +++AA + S G F Sbjct: 278 TVN-GFINVIPWLLVAVALWFVPRHAARHGASAWHIAGPVLLAAVALSLSVILPGAALKF 336 Query: 239 VAICFAGIGFKAASSLFWPIPQAYLDARIAAAVIALVNSIGNLGGFFAPATFGYLEQKTG 298 +C A AA +FW +P ++L AAA IA +N++GNLGGF A + TG Sbjct: 337 TMLCIAAPAIFAAQPVFWSLPPSFLSGPRAAAGIATINAVGNLGGFIAQNLVPVVRDATG 396 Query: 299 SIQGGLYALAAASVIAAGLVFLARTSGKK 327 S + ALAA ++ + L+F+ +K Sbjct: 397 SELAPMLALAAVLLVTSLLIFIVMGRLRK 425 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 207 bits (528), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 125/323 (38%), Positives = 186/323 (57%), Gaps = 9/323 (2%) Query: 1 MAFVHNETSFYILRFLLGVAEAGFFPGVVYYFTQWLPNSERGKAMAVFLSGSAIASILSG 60 M FV FY++RFLLG+AEAGFFPG++ Y T W P RG+ F++ A++ ++ G Sbjct: 116 MMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGG 175 Query: 61 PISGALLQIEGG--GLHXWQWMFIIEGLASVLLCFVVWRRLDSRPQDAAWLSDDERNSLA 118 PISG L+ GG GL WQWMF+IEG+ SV++ V LD+R A WL+D+E+ L Sbjct: 176 PISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLT 235 Query: 119 AIIAHEQRERQASKPVHVSSWSLLKDPQILLFCFIYFAIQLTIYGATFWLPSIIKKMGHF 178 IA E+ +++ P+ +++ P++ L IYF+ + +YG +FWLP++IK+ G Sbjct: 236 RNIAAEEAQKE-DAPIA----AIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVA 290 Query: 179 NDFQVGLFNSIPWIISIVAMYIFASLAARFRHQQAWVAATLIIAAAGMFASTT--GGPVF 236 + VGL +IP+ ++VAM + A A R R ++ +A + A G+ S Sbjct: 291 DPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTL 350 Query: 237 AFVAICFAGIGFKAASSLFWPIPQAYLDARIAAAVIALVNSIGNLGGFFAPATFGYLEQK 296 A A+ +G LFW +P A+L AAA IAL+NS+GNL GF +P G+L+ Sbjct: 351 AMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDT 410 Query: 297 TGSIQGGLYALAAASVIAAGLVF 319 T S G+Y LAA+ V+ A L Sbjct: 411 TRSTDSGMYLLAASMVLGALLTL 433 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 202 bits (514), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 122/310 (39%), Positives = 172/310 (55%), Gaps = 17/310 (5%) Query: 1 MAFVHNETSFYILRFLLGVAEAGFFPGVVYYFTQWLPNSERGKAMAVFLSGSAIASILSG 60 M FV + +FY LRFLLGV EAGF PG++YY TQW P +AMAV L + + ++ G Sbjct: 108 MLFVTDVWTFYALRFLLGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGG 167 Query: 61 PISGALLQ--IEGGGLHXWQWMFIIEGLASVLLCFVVWRRLDSRPQDAAWLSDDERNSLA 118 P S ++ GGL WQWMF+ EG+ S+LL + L +P DA WL+D ++ +A Sbjct: 168 PASTWIMGHFAGAGGLAGWQWMFLAEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIA 227 Query: 119 AIIAHEQRERQASKPVHVSSW-SLLKDPQILLFCFIYFAIQLTIYGATFWLPSIIKKMGH 177 IA + P SS+ L +P++ + YF + +Y FWLPSI+K G Sbjct: 228 GDIAR-------AAPGQASSFGKALTEPKLYVLAAAYFCLICGVYAVGFWLPSILKSAGL 280 Query: 178 FNDFQVGLFNSIPWIISIVAMYIFASLAARF--RHQQAWVAATLIIAAAGMFASTTGGPV 235 + FQ+GL+++IP + IVAMY + R RH + + A L AG+ A Sbjct: 281 SDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERHLHSAITAVL---GAGLLAWAAYATS 337 Query: 236 F--AFVAICFAGIGFKAASSLFWPIPQAYLDARIAAAVIALVNSIGNLGGFFAPATFGYL 293 F A ++I A A+ S+FW IPQ +L AA IAL+NSIG GGFF+P G+ Sbjct: 338 FPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAGGIALINSIGLFGGFFSPTLIGWT 397 Query: 294 EQKTGSIQGG 303 ++ TGS+Q G Sbjct: 398 KEATGSLQAG 407 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 196 bits (498), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 120/324 (37%), Positives = 175/324 (54%), Gaps = 9/324 (2%) Query: 1 MAFVHNETSFYILRFLLGVAEAGFFPGVVYYFTQWLPNSERGKAMAVFLSGSAIASILSG 60 MAFV SFY++RFLLGVAEAGFFPG++ Y + W P+ RG+ +F+ ++ I+ Sbjct: 110 MAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGA 169 Query: 61 PISGALLQIEGG--GLHXWQWMFIIEGLASVLLCFVVWRRLDSRPQDAAWLSDDERNSLA 118 P+SG ++Q G G WQWMFI+EG+ SVL+ ++ +L R A WL+D E++ L Sbjct: 170 PLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQ 229 Query: 119 AIIAHEQRERQASKPVHVSSWSLLKDPQILLFCFIYFAIQLTIYGATFWLPSIIKKMGHF 178 I E +A+ H P++ L IYF + Y FWLP++I+ G Sbjct: 230 TNI-----ENEAAHYAHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVK 284 Query: 179 NDFQVGLFNSIPWIISIVAMYIFASLAARFRHQQAWVAATLIIAAAGMFAST--TGGPVF 236 + +G +IP + V M + + A R R ++ +A T ++ A G+ ST + V Sbjct: 285 DILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVV 344 Query: 237 AFVAICFAGIGFKAASSLFWPIPQAYLDARIAAAVIALVNSIGNLGGFFAPATFGYLEQK 296 A V + +G + LFW +P A+L AAA IA +NS GNLGGF AP GYL+ Sbjct: 345 AMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDL 404 Query: 297 TGSIQGGLYALAAASVIAAGLVFL 320 T S G+ ++ I A LVFL Sbjct: 405 TQSTTTGMLIISTTLFIGAALVFL 428