BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0047.p (498 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1748 [S] COG0397 Uncharacterized conserved protein Rso Ralsto... 548 e-155 VC1931 [S] COG0397 Uncharacterized conserved protein Vch Vibrio ... 438 e-122 ydiU [S] COG0397 Uncharacterized conserved protein Eco Escherich... 434 e-121 PA5023 [S] COG0397 Uncharacterized conserved protein Pae Pseudom... 434 e-121 Z2735 [S] COG0397 Uncharacterized conserved protein EcZ Escheric... 430 e-120 >RSc1748 [S] COG0397 Uncharacterized conserved protein Rso Ralstonia solanacearum Length = 525 Score = 548 bits (1412), Expect = e-155, Method: Compositional matrix adjust. Identities = 290/501 (57%), Positives = 337/501 (67%), Gaps = 22/501 (4%) Query: 19 ANAFAELPPAFFTRLQPTPLPQ-PYLVGVSADAAALIGIDPATAASEGFIDVFTGNVIAQ 77 A FA L F TRL P P+P PYLVG S +AAA +G+ A + +DVF GN IA Sbjct: 26 APGFARLGERFLTRLPPVPMPAAPYLVGFSPEAAAPLGLSRAGLDTPAGLDVFVGNAIAA 85 Query: 78 HSKPLAAVYSGHQFGVWAGQLGDGRAILLGDLPARDGGRMEIQLKGAGQTPYSRMGDGRA 137 S PLA VYSGHQFGVWAGQLGDGRA+LL +L DG E+QLKGAG TPYSRMGDGRA Sbjct: 86 WSDPLATVYSGHQFGVWAGQLGDGRALLLAELQTADGP-CEVQLKGAGLTPYSRMGDGRA 144 Query: 138 VLRSSIREFLCSEAMAGLGIPTTRALCVTGSDLQVRRETLETTAVVTRMSPSFIRFGSFE 197 VLRSSIREFLCSEAMAGLGIPTTRALCV G+D VRRET+ET AVVTR++PSF+RFG FE Sbjct: 145 VLRSSIREFLCSEAMAGLGIPTTRALCVIGADAPVRRETIETAAVVTRLAPSFVRFGHFE 204 Query: 198 HWYYNKRHDELKLLADNVIANFYPELLDADNPYRALLAEVTRRTAHLMAQWQAVGFMHGV 257 H+ N++ EL+ LAD VI FYP PY ALL EV RRTA L+AQWQAVGF HGV Sbjct: 205 HFAANEKLPELRALADFVIDRFYPACRAEPQPYLALLREVGRRTAALIAQWQAVGFCHGV 264 Query: 258 MNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDQQGRYSYQMQPRIGQWNCFALGQALL 317 MNTDNMSILGLTLDYGPFGF++ FDA HICNH+D GRY+Y QP+I WN F L QALL Sbjct: 265 MNTDNMSILGLTLDYGPFGFLDGFDANHICNHSDTGGRYAYAQQPQIAYWNLFCLAQALL 324 Query: 318 PLIGS-----------------VEDTEAALGQYEAEFAAKNDDLLHAKLGLATRQADDDK 360 PL GS ++ + AL Y + AKLGL D+ Sbjct: 325 PLCGSDPTAFTDLSDEAQAQPAIDAAQEALLVYRDTYGEAFYARYRAKLGLTQAHDGDEA 384 Query: 361 LFESMFAILQAGHVDFTLFFRRLSDLRAGDNGGD---EALRDLFIERPSFDAWAGQYRAR 417 LF +F +L D+TLFFR L+D+R D +RD+F +R S DAW YR R Sbjct: 385 LFGDLFKLLHTQRADYTLFFRHLADVRRDDTPAQAQARTVRDVFFDRDSADAWLAAYRQR 444 Query: 418 LQQENSVDAARKLAMDASNPKYVLRNYLAQVAIDKAQNKDFSEVAKLQEILRRPFDEQPE 477 LQ E + DAAR AM NPKYVLRN+LA++AI +A KDFSEV L+ +L RPFD+ P Sbjct: 445 LQTEPAPDAARAEAMRRVNPKYVLRNHLAEIAIRRAGEKDFSEVENLRAVLARPFDDHPG 504 Query: 478 HDKYADLPPDWASHLEVSCSS 498 + YA PDWA+ LEVSCSS Sbjct: 505 FEHYAGPAPDWAASLEVSCSS 525 >VC1931 [S] COG0397 Uncharacterized conserved protein Vch Vibrio cholerae Length = 508 Score = 438 bits (1127), Expect = e-122, Method: Compositional matrix adjust. Identities = 237/490 (48%), Positives = 306/490 (62%), Gaps = 12/490 (2%) Query: 15 ALPFANAFAELPPAFFTRLQPTPLPQPYLVGVSADAAALIGIDPATAASEGFIDVFTGNV 74 A+ + FA LP AF+T + P PL ++ A G+ P E + + + Sbjct: 25 AVHLSRRFAALPQAFYTPVHPQPLQNVRWGMWNSRLAQQFGL-PEAPNDELLLSLSGQQL 83 Query: 75 IAQHSKPLAAVYSGHQFGVWAGQLGDGRAILLGDLPARDGGRMEIQLKGAGQTPYSRMGD 134 A S P+A Y+GHQFGV+ LGDGR +LL ++ + G +I LKGAG TPYSRMGD Sbjct: 84 PADFS-PVAMKYAGHQFGVYNPDLGDGRGLLLAEMATKQGEVFDIHLKGAGLTPYSRMGD 142 Query: 135 GRAVLRSSIREFLCSEAMAGLGIPTTRALCVTGSDLQVRRETLETTAVVTRMSPSFIRFG 194 GRAVLRSS+RE+LCSEAMAGLGI TTRAL + S+ V RE E A++ R++ + +RFG Sbjct: 143 GRAVLRSSLREYLCSEAMAGLGIATTRALALMSSETPVYREREERGALLVRLAHTHVRFG 202 Query: 195 SFEHWYYNKRHDELKLLADNVIANFYPELLDADNPYRALLAEVTRRTAHLMAQWQAVGFM 254 FEH++Y +H LKLLAD VI +P+ + PY A ++V RTA ++AQWQA GF Sbjct: 203 HFEHFFYTDQHANLKLLADKVIEWHFPDCVQTSKPYAAWFSQVVERTALMIAQWQAYGFN 262 Query: 255 HGVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDQQGRYSYQMQPRIGQWNCFALGQ 314 HGVMNTDNMSILG T DYGPF F++ +D ICNH+D QGRY++ QPRIG WN AL Sbjct: 263 HGVMNTDNMSILGETFDYGPFAFLDDYDPNFICNHSDYQGRYAFDQQPRIGLWNLSALAH 322 Query: 315 ALLPLIGSVEDTEAALGQYEAEFAAKNDDLLHAKLGLATRQADDDKLFESMFAILQAGHV 374 AL PLI +D EAALG Y L+ AKLGLAT+Q D +LF FA+L H Sbjct: 323 ALSPLIDK-DDLEAALGSYSERLNLHFSRLMRAKLGLATQQEGDGELFADFFALLANNHT 381 Query: 375 DFTLFFRRLSDLRAGDNGGDEALRDLFIERPSFDAWAGQYRAR----LQQENSVDAARKL 430 D+T F R LS L D G+EA+ DL ++R + W +Y R L QE + R+ Sbjct: 382 DYTRFLRELSCL---DRQGNEAVIDLVLDREAAKTWLTRYLERAARELGQEGRPISTRER 438 Query: 431 --AMDASNPKYVLRNYLAQVAIDKAQNKDFSEVAKLQEILRRPFDEQPEHDKYADLPPDW 488 AM NPKY+LRNYLAQ AI+ A+ DF E+ +L +L P+ E PE ++YA LPP+W Sbjct: 439 CQAMRQVNPKYILRNYLAQQAIEFAERGDFEEMQRLATVLASPYAEHPEFERYAKLPPEW 498 Query: 489 ASHLEVSCSS 498 LE+SCSS Sbjct: 499 GKKLEISCSS 508 >ydiU [S] COG0397 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 478 Score = 434 bits (1117), Expect = e-121, Method: Compositional matrix adjust. Identities = 229/484 (47%), Positives = 300/484 (61%), Gaps = 7/484 (1%) Query: 15 ALPFANAFAELPPAFFTRLQPTPLPQPYLVGVSADAAALIGIDPATAASEGFIDVFTGNV 74 L F + + P +T L PTPL L+ + + A + I P++ G V+ G Sbjct: 2 TLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSI-PSSLFKNG-AGVWGGEA 59 Query: 75 IAQHSKPLAAVYSGHQFGVWAGQLGDGRAILLGDLPARDGGRMEIQLKGAGQTPYSRMGD 134 + PLA VYSGHQFGVWAGQLGDGR ILLG+ DG M+ LKGAG TPYSRMGD Sbjct: 60 LLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGD 119 Query: 135 GRAVLRSSIREFLCSEAMAGLGIPTTRALCVTGSDLQVRRETLETTAVVTRMSPSFIRFG 194 GRAVLRS+IRE L SEAM LGIPTTRAL + SD V RET E A++ R++PS +RFG Sbjct: 120 GRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFG 179 Query: 195 SFEHWYYNKRHDELKLLADNVIANFYPELLDADNPYRALLAEVTRRTAHLMAQWQAVGFM 254 FEH+YY + ++++ LAD I +++ L D ++ YR ++V RTA L+AQWQ VGF Sbjct: 180 HFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLWFSDVVARTASLIAQWQTVGFA 239 Query: 255 HGVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDQQGRYSYQMQPRIGQWNCFALGQ 314 HGVMNTDNMS+LGLTLDYGPFGF++ ++ ICNH+D QGRYS+ QP + WN L Q Sbjct: 240 HGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQ 299 Query: 315 ALLPLIGSVEDTEAALGQYEAEFAAKNDDLLHAKLGLATRQADDDKLFESMFAILQAGHV 374 L P + +V+ AL Y+ + + KLG T Q +D+ L +F+++ Sbjct: 300 TLSPFV-AVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERS 358 Query: 375 DFTLFFRRLSDLRAGDNGGDEALRDLFIERPSFDAWAGQYRARLQQENSVDAARKLAMDA 434 D+T FR LS + LRD FI+R +FD W +YR RLQQ+ D+ R+ M + Sbjct: 359 DYTRTFRMLS--LTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQS 416 Query: 435 SNPKYVLRNYLAQVAIDKAQNKDFSEVAKLQEILRRPFDEQPEHDKYADLPPDWASHLEV 494 NP VLRN+LAQ AI+ A+ D +E+ +L E LR PF ++ D Y PPDW LEV Sbjct: 417 VNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRD--DDYVSRPPDWGKRLEV 474 Query: 495 SCSS 498 SCSS Sbjct: 475 SCSS 478 >PA5023 [S] COG0397 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 486 Score = 434 bits (1116), Expect = e-121, Method: Compositional matrix adjust. Identities = 235/486 (48%), Positives = 318/486 (65%), Gaps = 9/486 (1%) Query: 16 LPFANAFAELPPAFFTRLQPTPLPQPYLVGVSADAAALIGIDPATAASEGFIDVFTGNVI 75 L F N FA L AF T + P P+ +P LV S A AL+ + T+ F ++F G+ + Sbjct: 7 LDFDNRFARLGGAFSTEVLPDPIAEPRLVVASPAALALLDLPAETSDEALFAELFGGHKL 66 Query: 76 AQHSKPLAAVYSGHQFGVWAGQLGDGRAILLGDLPARDGGRMEIQLKGAGQTPYSRMGDG 135 ++P A VYSGHQFG + +LGDGR +LLG++ + G ++ LKGAGQTPYSRMGDG Sbjct: 67 WSEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVINQAGEHWDLHLKGAGQTPYSRMGDG 126 Query: 136 RAVLRSSIREFLCSEAMAGLGIPTTRALCVTGSDLQVRRETLETTAVVTRMSPSFIRFGS 195 RAVLRSSIREFL SEA+ LGIP++RALCV GS V RE E+ A + R++PS +RFG Sbjct: 127 RAVLRSSIREFLASEALPALGIPSSRALCVIGSSTPVWREKKESAATLLRLAPSHVRFGH 186 Query: 196 FEHWYYNKRHDELKLLADNVIANFYPELLDADNPYRALLAEVTRRTAHLMAQWQAVGFMH 255 FE++YY ++HD+LK LA V+ + + + A+ PY A+ +V R A L+A+WQA GF H Sbjct: 187 FEYFYYTRQHDQLKQLAAFVLEHHFADCNAAERPYAAMFRQVVERNAELIARWQAYGFCH 246 Query: 256 GVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDQQGRYSYQMQPRIGQWNCFALGQA 315 GVMNTDNMSILG+T DYGP+ F++ FDA HICNH+D GRYS+ Q I WN AL QA Sbjct: 247 GVMNTDNMSILGITFDYGPYAFLDDFDANHICNHSDDAGRYSFSNQVPIAHWNLAALAQA 306 Query: 316 LLPLIGSVEDTEAALGQYEAEFAAKNDDLLHAKLGLATRQADDDKLFESMFAILQAGHVD 375 L PL+ V++ A+L + + A DL+ +LGL +D L + + +Q VD Sbjct: 307 LTPLV-EVDELRASLDLFLPLYQAHYLDLMRRRLGLGVAAENDHALVQELLQRMQGSAVD 365 Query: 376 FTLFFRRLSDLRAGDNGGDEA---LRDLFIERPSFDAWAGQYRARLQQENSVDAARKLAM 432 ++LFFRRL G+ + A LRD F++R +FD WA YR R+++E +R+ M Sbjct: 366 YSLFFRRL-----GEETPERALASLRDDFVDREAFDRWAEAYRRRVEEEGGDQESRRRRM 420 Query: 433 DASNPKYVLRNYLAQVAIDKAQNKDFSEVAKLQEILRRPFDEQPEHDKYADLPPDWASHL 492 A NP YVLRNYLAQ AI+ A+ D++EV L ++L RPF+EQP +++ PPDW HL Sbjct: 421 HAVNPLYVLRNYLAQQAIEAAEQGDYTEVRLLHQVLSRPFEEQPGMERFTRRPPDWGRHL 480 Query: 493 EVSCSS 498 E+SCSS Sbjct: 481 EISCSS 486 >Z2735 [S] COG0397 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 478 Score = 430 bits (1105), Expect = e-120, Method: Compositional matrix adjust. Identities = 229/484 (47%), Positives = 297/484 (61%), Gaps = 7/484 (1%) Query: 15 ALPFANAFAELPPAFFTRLQPTPLPQPYLVGVSADAAALIGIDPATAASEGFIDVFTGNV 74 L F + + P +T L PTPL L+ + + A + I P++ G V+ G Sbjct: 2 TLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSI-PSSLFKNG-AGVWGGET 59 Query: 75 IAQHSKPLAAVYSGHQFGVWAGQLGDGRAILLGDLPARDGGRMEIQLKGAGQTPYSRMGD 134 + PLA VYSGHQFGVWAGQLGDGR ILLG+ DG M+ LKGAG TPYSRMGD Sbjct: 60 LLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGD 119 Query: 135 GRAVLRSSIREFLCSEAMAGLGIPTTRALCVTGSDLQVRRETLETTAVVTRMSPSFIRFG 194 GRAVLRS+IRE L SEAM LGIPTTRAL + SD V RET+E A++ R++PS +RFG Sbjct: 120 GRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVEPGAMLMRVAPSHLRFG 179 Query: 195 SFEHWYYNKRHDELKLLADNVIANFYPELLDADNPYRALLAEVTRRTAHLMAQWQAVGFM 254 FEH+YY + D+++ LAD I +++ L D ++ YR +V RTA L+AQWQ VGF Sbjct: 180 HFEHFYYRREPDKVRQLADFAIRHYWSHLEDDEDKYRLWFNDVVARTASLIAQWQTVGFA 239 Query: 255 HGVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDQQGRYSYQMQPRIGQWNCFALGQ 314 HGVMNTDNMS+LGLTLDYGPFGF+ ++ ICNH+D QGRYS+ QP + W L Q Sbjct: 240 HGVMNTDNMSLLGLTLDYGPFGFLNDYEPGFICNHSDHQGRYSFDNQPAVALWILQRLAQ 299 Query: 315 ALLPLIGSVEDTEAALGQYEAEFAAKNDDLLHAKLGLATRQADDDKLFESMFAILQAGHV 374 L P + +V+ AL Y+ + KLG T Q +D+ L +F+++ Sbjct: 300 TLSPFV-AVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERS 358 Query: 375 DFTLFFRRLSDLRAGDNGGDEALRDLFIERPSFDAWAGQYRARLQQENSVDAARKLAMDA 434 D+T FR LS + LRD FI+R +FD W +YR RLQQ+ D+ R+ M + Sbjct: 359 DYTRTFRMLS--LTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQS 416 Query: 435 SNPKYVLRNYLAQVAIDKAQNKDFSEVAKLQEILRRPFDEQPEHDKYADLPPDWASHLEV 494 NP VLRN+LAQ AI+ A+ D +E+ +L E LR PF ++ D Y PPDW LEV Sbjct: 417 VNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRD--DDYVSRPPDWGKRLEV 474 Query: 495 SCSS 498 SCSS Sbjct: 475 SCSS 478