BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0029.p (309 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0239 [GER] COG0697 Permeases of the drug/metabolite transporte... 191 1e-48 mlr5160 [GER] COG0697 Permeases of the drug/metabolite transport... 147 3e-35 RSp0133 [GER] COG0697 Permeases of the drug/metabolite transport... 145 8e-35 AGl1685 [GER] COG0697 Permeases of the drug/metabolite transport... 130 4e-30 SMc02817 [GER] COG0697 Permeases of the drug/metabolite transpor... 121 2e-27 >PA0239 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 191 bits (486), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 107/283 (37%), Positives = 164/283 (57%), Gaps = 7/283 (2%) Query: 14 GIIFLISALWTLSLLDTAGKLLGMAGYHVVMIAWMRYSINTVFMAATLMPLYKRRHGRSI 73 GI+ + +A++ + D K L Y +VM+ W RY ++T+ M A +P R+G ++ Sbjct: 17 GILLICAAVFLFASHDGLSKFLS-GFYPIVMVVWARYLVHTLLMVAVFVP----RNGLAV 71 Query: 74 LHSTRPRLQVLRALALLLSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAVSPWLLGETTYI 133 + S RP +Q+ RAL L+ ++L F + L+ +PLAE TA+NF APL+V A+S LL E + Sbjct: 72 IRSRRPLMQLARALCLIGTSLFFTTGLRYLPLAEATAVNFLAPLLVTALSVPLLKEKVSL 131 Query: 134 SRWVAVAVGFAGMLIVIRPGGDIPAHGVVLGLLSAATYATVSILNRKANQADDPMVTLFY 193 +W+AV GF G+L ++RPGG + + L SA + +L R +D P + F Sbjct: 132 GQWLAVLTGFIGVLFIVRPGGALFTPAALFPLGSALCFGLYQLLTRMLANSDSPTTSNFL 191 Query: 194 GGLVGMVVSSLMVPFFWSPHTPDATEWMILASTGITSTIGHFFMNSAYRHAEASVLTPFA 253 G+ ++ SL+VPFFW TP +++ + G GH + A+RHA + L PF+ Sbjct: 192 AGIFNTLIMSLLVPFFW--QTPSLLHGLMMIALGGCGMGGHLLLTQAFRHAPPATLAPFS 249 Query: 254 YSQIISASAMGWLVFNQFPDAVTILGIAIICASGMGIAYVEHR 296 Y QII A +G LVF PDA +LGI +ICASG+ +A+ R Sbjct: 250 YGQIIFAGLLGLLVFGHVPDAWALLGILVICASGLVVAWRRGR 292 >mlr5160 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 313 Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 98/288 (34%), Positives = 152/288 (52%), Gaps = 11/288 (3%) Query: 25 LSLLDTAGKLLGMAGYHVVMIAWMRYSINTVFMAATLMPLYKRRHGRSILHSTRPRL--Q 82 + LDT+ K L +AG +++AW+R++++ V + L R R L L Sbjct: 27 FTFLDTSSKYLVLAGVSALIVAWVRFAVHVVLVGTLL------RGWRDPLRFRPVNLPAH 80 Query: 83 VLRALALLLSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAVSPWLLGETTYISRWVAVAVG 142 VLR + L ST+ L+ + LAE T++ F P+++ A++ LLGE RW+A+ Sbjct: 81 VLRGVFLFGSTMCNILALRSLQLAETTSIYFFGPMVITALAGPLLGEWAGWRRWLAILAA 140 Query: 143 FAGMLIVIRPGGDIPAHGVVLGLLSAATYATVSILNRKANQADDPMVTLFYGGLVGMVVS 202 FAG+LI+ RPG + G + L S + I+ R+ + + + + L V+ Sbjct: 141 FAGVLIITRPGVGVFGIGHLFALGSMLSNCFYVIMTRRMSSTETSESLILFSALAPTVLL 200 Query: 203 SLMVPFFWS-PHTPDATEWMILASTGITSTIGHFFMNSAYRHAEASVLTPFAYSQIISAS 261 M+PF +S PH D W IL G+ +GH+ + AYR A + L P+ YSQ++ Sbjct: 201 LPMLPFSFSLPH--DGWHWFILLMLGVFGGVGHWLLVQAYRLATTTALAPYPYSQMVWMV 258 Query: 262 AMGWLVFNQFPDAVTILGIAIICASGMGIAYVEHRRAHPLRAAAETTA 309 GW+VF QFPD T++G AII ASG+ I + EHR RAA++ A Sbjct: 259 ISGWIVFKQFPDRWTLVGAAIIVASGLYIVHREHRLRLQSRAASDVEA 306 >RSp0133 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 145 bits (367), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 110/288 (38%), Positives = 153/288 (53%), Gaps = 10/288 (3%) Query: 14 GIIFLISALWTLSLLDTAGKLLGMAGYHVVMIAWMRYSINTVFMAATLMPLYKRRHGRSI 73 GI FLI+A+ ++ DT K + + VVM W RY V ATL+P GRS+ Sbjct: 29 GIAFLIAAVAFFAVFDTLTKYISIT-VPVVMALWFRYLFQMVATGATLLP----SRGRSL 83 Query: 74 LHSTRPRLQVLRALALLLSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAVSPWLLGETTYI 133 L + RP LQV+R L LLL +L F L+ +P+ + TA+ PL+V V+ LGE Sbjct: 84 LRTRRPWLQVVRGLLLLLVSLFSFLSLRRMPVGDVTAIVMLTPLVVTFVAAVSLGEQVSA 143 Query: 134 SRWVAVAVGFAGMLIVIRPGGDIPAHGVVLGLLSAATYATVSILNRKANQADDPMVTLFY 193 +RW+ +A GF G L+VIRPGG G++L L A ++ + D+ T FY Sbjct: 144 TRWIFMAGGFFGALMVIRPGGAAFDWGMLLPLGMVVANAAFQVVTSRLANVDEAGTTQFY 203 Query: 194 GGLVGMVVSSLMVPFFWSPHTPDATEWMILASTGITSTIGHFFMNSAYRHAEASVLTPFA 253 G VG ++ + M+PF W W +L GI S+ GH + AY A ++LTP+ Sbjct: 204 TGAVGALLLTCMLPFGW--QALGGKWWWLLILIGIVSSSGHALLIMAYTRAPVAMLTPYL 261 Query: 254 YSQIISASAMGWLVFNQFPDAVTILGIAIIC---ASGMGIAYVEHRRA 298 Y QI A GWLVF+ PD ++ GIAII A+G +A E R A Sbjct: 262 YMQIGFAMIGGWLVFSHVPDGWSVAGIAIIAMCGAAGTWVAARERRMA 309 >AGl1685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 130 bits (327), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 95/300 (31%), Positives = 154/300 (51%), Gaps = 9/300 (3%) Query: 9 PRLWLGIIFLISALWTLSLLDTAGKLLGMAGYHVVMIAWMRYSINTVFMAATLMPLYKRR 68 P G ++ + A + D K LG A Y V +A +RY VF+ LM Sbjct: 2 PSAKTGFLYALVAFTIFAAQDGISKHLGSA-YPPVFVAMLRYWAFAVFV--LLMAARSAG 58 Query: 69 HGRSILHSTRPRLQVLRALALLLSTLIFFSVLK--IVPLAEGTAMNFCAPLIVLAVSPWL 126 R + + RP LQ+ R + LL+ I FS+ +V LA ++ APLIV A+S L Sbjct: 59 GIRGAVMANRPWLQISRGV--LLAVQIVFSIFSFAVVGLAHSHSILASAPLIVAALSMPL 116 Query: 127 LGETTYISRWVAVAVGFAGMLIVIRPGGDIPAHGVVLGLLSAATYATVSILNRKANQADD 186 LGE RW A+ VGF G+L++++P GD + +++ ++A A S+L R +++D Sbjct: 117 LGEHVGWRRWCAIFVGFIGVLVILKPDGDGFDNKLIITFVAAFMLALYSVLTRLGSKSDS 176 Query: 187 PMVTLFYGGLVGMVVSSLMVPFFWSPHTPDATEWMILASTGITSTIGHFFMNSAYRHAEA 246 M + FY G+ G +L+ PF+W P P WM+ + IT GH+ + A+ A+A Sbjct: 177 AMTSFFYTGVAGAAALTLVGPFYWVPLAPQDWGWML--ALCITGMSGHYCLIKAFELADA 234 Query: 247 SVLTPFAYSQIISASAMGWLVFNQFPDAVTILGIAIICASGMGIAYVEHRRAHPLRAAAE 306 + + PF+Y Q++ S +G ++ + + + G AI+ A+G+ + EH A R A Sbjct: 235 ASVQPFSYYQLVLVSIIGVTIYGEVVTSNMVTGAAIVIAAGLFTIWREHVVARRNRREAN 294 >SMc02817 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 317 Score = 121 bits (304), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 93/297 (31%), Positives = 144/297 (48%), Gaps = 12/297 (4%) Query: 7 SHPRLWLGIIFLISALWTLSLLDTAGKLLGMAGYHVVMIAWMRYSINTVFMAATLMPLYK 66 H R+ G+ ++ ++ L+D KL +A I R+ + VF ++P+ Sbjct: 12 DHNRISYGLTLMVLSVLLSPLIDIFSKL-AIATVPSAEITAARFLLQIVF----ILPIVL 66 Query: 67 RRHGRSILHSTRPRLQVLRALALLLSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAVSPWL 126 R L + L LR L+++ L F + LK++ +A+ A+ F P+I+ + Sbjct: 67 VRGTLFDLTWRKSALHALRGGLLVVTMLSFITTLKVMEVADAIAIFFVEPIILTILGSIF 126 Query: 127 LGETTYISRWVAVAVGFAGMLIVIRPGGDIPAHGVVLGLLSAATYATVSILNRKANQADD 186 L ET R+ A AVGF G L+VI+P +L +++A A ++ R Q +D Sbjct: 127 LKETIGWRRYTACAVGFLGSLLVIQPSMQEVGLVALLPIVAAFGLAVFLLVTRMVAQNED 186 Query: 187 PMVTLFYGGLVGMVVSSLMVPF-------FWSPHTPDATEWMILASTGITSTIGHFFMNS 239 P F+ G+ G + ++ F + P PD W L G+T+TI Sbjct: 187 PWSMQFHAGIWGGLFCLALLWFGEGSGSSVFDPVWPDGRAWYYLLGVGVTATISGVLGVY 246 Query: 240 AYRHAEASVLTPFAYSQIISASAMGWLVFNQFPDAVTILGIAIICASGMGIAYVEHR 296 AYR A ASVL P Y +I+SA+ GWLVF PDA+ LGIAII SG+ I + E + Sbjct: 247 AYRAAPASVLAPLQYLEIVSATIFGWLVFGDLPDALKWLGIAIIIGSGLYIIWRERQ 303