BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0001.p (337 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 453 e-127 gabD [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Esche... 436 e-122 ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Esch... 433 e-121 ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Es... 433 e-121 STM2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Sa... 432 e-121 >PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 483 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 218/296 (73%), Positives = 246/296 (83%) Query: 27 LQLKDPSLLRQQAYINGAWCNADGGGTHAVNNPATGDELGTVPDMGTDETRRAIEAAQAA 86 +QLKD L RQQAY++GAW +AD G T VNNPATG+ +G+VP MG ETRRAIEAA A Sbjct: 1 MQLKDAKLFRQQAYVDGAWVDADNGQTIKVNNPATGEIIGSVPKMGAAETRRAIEAADKA 60 Query: 87 WPAWRKKTARERAAILRKWNDLMLANADDLALIMTAEQGKPLAESKGEIAYAASFIEWFG 146 PAWR TA+ERA LR+W DLM+ N DDLA +MT EQGKPLAE+KGEIAYAASF+EWFG Sbjct: 61 LPAWRALTAKERANKLRRWFDLMIENQDDLARLMTIEQGKPLAEAKGEIAYAASFLEWFG 120 Query: 147 EEAKRTYGDTIPSPVPGNRIVVIKEPIGVCAAITPWNFPAAMITRKAGPALAAGCPMVLK 206 EEAKR YGDTIP P RI+VIK+PIGV AAITPWNFP+AMITRKAGPALAAGC MVLK Sbjct: 121 EEAKRIYGDTIPGHQPDKRIIVIKQPIGVTAAITPWNFPSAMITRKAGPALAAGCTMVLK 180 Query: 207 PAQATPFSALALAVLAERAGVPAGVFSVVTGSSKVIGAEMTGNPVVRKLSFTGSTETGKL 266 PA TP+SALALA LAERAG+P GVFSVVTGS+ +G E+T NP+VRKL+FTGSTE G+ Sbjct: 181 PASQTPYSALALAELAERAGIPKGVFSVVTGSAGEVGGELTSNPIVRKLTFTGSTEIGRQ 240 Query: 267 LMQQCAATIKKVSLELGGNAPFIVFDDADLDAAVEGAIASKFRNTGQTCVCAXCCW 322 LM +CA IKKVSLELGGNAPFIVFDDADLDAAVEGA+ SK+RN GQTCVCA + Sbjct: 241 LMAECAQDIKKVSLELGGNAPFIVFDDADLDAAVEGALISKYRNNGQTCVCANRLY 296 >gabD [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Escherichia coli K12 Length = 482 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 213/296 (71%), Positives = 240/296 (81%) Query: 27 LQLKDPSLLRQQAYINGAWCNADGGGTHAVNNPATGDELGTVPDMGTDETRRAIEAAQAA 86 ++L D +L RQQA ING W +A+ G V NPA GD+LG+VP MG DETR AI+AA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 87 WPAWRKKTARERAAILRKWNDLMLANADDLALIMTAEQGKPLAESKGEIAYAASFIEWFG 146 PAWR TA+ERA ILR W +LM+ + DDLA +MT EQGKPLAE+KGEI+YAASFIEWF Sbjct: 61 LPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 147 EEAKRTYGDTIPSPVPGNRIVVIKEPIGVCAAITPWNFPAAMITRKAGPALAAGCPMVLK 206 EE KR YGDTIP R++VIK+PIGV AAITPWNFPAAMITRKAGPALAAGC MVLK Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 207 PAQATPFSALALAVLAERAGVPAGVFSVVTGSSKVIGAEMTGNPVVRKLSFTGSTETGKL 266 PA TPFSALALA LA RAGVPAGVF+VVTGS+ +G E+T NP+VRKLSFTGSTE G+ Sbjct: 181 PASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ 240 Query: 267 LMQQCAATIKKVSLELGGNAPFIVFDDADLDAAVEGAIASKFRNTGQTCVCAXCCW 322 LM+QCA IKKVSLELGGNAPFIVFDDADLD AVEGA+ASKFRN GQTCVCA + Sbjct: 241 LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLY 296 >ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 482 Score = 433 bits (1114), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/296 (71%), Positives = 239/296 (80%) Query: 27 LQLKDPSLLRQQAYINGAWCNADGGGTHAVNNPATGDELGTVPDMGTDETRRAIEAAQAA 86 ++L D +L RQQA ING W +A+ G V NPA GD+LG+VP MG DETR AI+AA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 87 WPAWRKKTARERAAILRKWNDLMLANADDLALIMTAEQGKPLAESKGEIAYAASFIEWFG 146 P WR TA+ERA ILR W +LM+ + DDLA +MT EQGKPLAE+KGEI+YAASFIEWF Sbjct: 61 LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 147 EEAKRTYGDTIPSPVPGNRIVVIKEPIGVCAAITPWNFPAAMITRKAGPALAAGCPMVLK 206 EE KR YGDTIP R++VIK+PIGV AAITPWNFPAAMITRKAGPALAAGC MVLK Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 207 PAQATPFSALALAVLAERAGVPAGVFSVVTGSSKVIGAEMTGNPVVRKLSFTGSTETGKL 266 PA TPFSALALA LA RAG+PAGVF+VVTGS+ +G E+T NP+VRKLSFTGSTE G+ Sbjct: 181 PASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ 240 Query: 267 LMQQCAATIKKVSLELGGNAPFIVFDDADLDAAVEGAIASKFRNTGQTCVCAXCCW 322 LM+QCA IKKVSLELGGNAPFIVFDDADLD AVEGA+ASKFRN GQTCVCA + Sbjct: 241 LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLY 296 >ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Escherichia coli O157:H7 Length = 482 Score = 433 bits (1114), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/296 (71%), Positives = 239/296 (80%) Query: 27 LQLKDPSLLRQQAYINGAWCNADGGGTHAVNNPATGDELGTVPDMGTDETRRAIEAAQAA 86 ++L D +L RQQA ING W +A+ G V NPA GD+LG+VP MG DETR AI+AA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 87 WPAWRKKTARERAAILRKWNDLMLANADDLALIMTAEQGKPLAESKGEIAYAASFIEWFG 146 P WR TA+ERA ILR W +LM+ + DDLA +MT EQGKPLAE+KGEI+YAASFIEWF Sbjct: 61 LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 147 EEAKRTYGDTIPSPVPGNRIVVIKEPIGVCAAITPWNFPAAMITRKAGPALAAGCPMVLK 206 EE KR YGDTIP R++VIK+PIGV AAITPWNFPAAMITRKAGPALAAGC MVLK Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 207 PAQATPFSALALAVLAERAGVPAGVFSVVTGSSKVIGAEMTGNPVVRKLSFTGSTETGKL 266 PA TPFSALALA LA RAG+PAGVF+VVTGS+ +G E+T NP+VRKLSFTGSTE G+ Sbjct: 181 PASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ 240 Query: 267 LMQQCAATIKKVSLELGGNAPFIVFDDADLDAAVEGAIASKFRNTGQTCVCAXCCW 322 LM+QCA IKKVSLELGGNAPFIVFDDADLD AVEGA+ASKFRN GQTCVCA + Sbjct: 241 LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLY 296 >STM2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Salmonella typhimurium LT2 Length = 482 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/296 (71%), Positives = 240/296 (81%) Query: 27 LQLKDPSLLRQQAYINGAWCNADGGGTHAVNNPATGDELGTVPDMGTDETRRAIEAAQAA 86 +QL D +L RQQA+I+G W +A GG V+NPA G LG VP MG +ETR AI AA A Sbjct: 1 MQLNDSTLFRQQAFIDGDWRDARGGDVIPVSNPANGKPLGNVPKMGAEETRDAINAANRA 60 Query: 87 WPAWRKKTARERAAILRKWNDLMLANADDLALIMTAEQGKPLAESKGEIAYAASFIEWFG 146 PAWR TA+ERA ILR+W +LM+ + DDLA +MT EQGKPLAE+KGEI+YAASFIEWF Sbjct: 61 LPAWRALTAKERANILRRWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 147 EEAKRTYGDTIPSPVPGNRIVVIKEPIGVCAAITPWNFPAAMITRKAGPALAAGCPMVLK 206 EE KR YGDTIP R++VIK+PIGV AAITPWNFP+AMITRKAGPALAAGC MVLK Sbjct: 121 EEGKRIYGDTIPGHQADKRLLVIKQPIGVTAAITPWNFPSAMITRKAGPALAAGCTMVLK 180 Query: 207 PAQATPFSALALAVLAERAGVPAGVFSVVTGSSKVIGAEMTGNPVVRKLSFTGSTETGKL 266 PA TPFSALALA LA+RAG+PAGVF+VVTGS+ IG E+T NP+VRKLSFTGSTE G+ Sbjct: 181 PASQTPFSALALAELAQRAGIPAGVFNVVTGSAGDIGGELTSNPLVRKLSFTGSTEIGRQ 240 Query: 267 LMQQCAATIKKVSLELGGNAPFIVFDDADLDAAVEGAIASKFRNTGQTCVCAXCCW 322 LM+QCA IKKVSLELGGNAPFIVFDDADLD AVEGA+ASKFRN GQTCVCA + Sbjct: 241 LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLY 296