BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0079.p (388 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4886 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 243 7e-64 RSp0488 [T] COG0642 Signal transduction histidine kinase Rso Ral... 238 2e-62 ZybcZ [T] COG0642 Signal transduction histidine kinase EcZ Esche... 210 4e-54 ECs0608 [T] COG0642 Signal transduction histidine kinase Ecs Esc... 210 4e-54 PA1438 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 204 2e-52 >PA4886 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 463 Score = 243 bits (619), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 131/275 (47%), Positives = 183/275 (66%), Gaps = 3/275 (1%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 + P ++ +AAEI P +L TRL APAEL+Q+A + NAML+RL++GY+ L QFSAD Sbjct: 191 GLRPLRTLAAKAAEIHPTSLDTRLDVAAAPAELQQVAQSFNAMLERLDDGYQRLQQFSAD 250 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 LAHEIRTP+ LMG QV L Q R+ EEY+ L+ SN EEL R++R++E+ILFLA+ D + Sbjct: 251 LAHEIRTPIGSLMGHGQVALRQPRSNEEYQALIASNQEELERIARMVESILFLARADDVR 310 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNA 287 V+RS +DL EEL++ A+YFEG+A ER + +V + L L +RRA+SNL+ NA Sbjct: 311 AAVERSRLDLGEELRRQAEYFEGLAEERGLSLDVQVSGQLRADPQL--FRRALSNLLANA 368 Query: 288 VRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGL 347 +RY A + I + + + V N + + + R+FDRFYRGD +RS+ +S+GL Sbjct: 369 IRYASADSLIEVRGLRRSGEFLLSVENACDRLPAEPLSRLFDRFYRGDAARSD-AQSSGL 427 Query: 348 GLAIVKAIMTVHGGTAAVACSADGWIAFSLRFPTR 382 GLAIV+AIM +HGG A + A G I F L FP + Sbjct: 428 GLAIVQAIMRLHGGRAEASAPAPGRIRFDLAFPAQ 462 Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 37/81 (45%), Positives = 55/81 (67%) Query: 29 GMYLYTSARQSLEVRADYTLIGRVEHFRNLLHDLYNVEQMEQRPALFESMLGNEQDVRIF 88 G YLY S +++ R+D + GRVEHFRNLL D + +++ RP LFE+MLGNEQD+ + Sbjct: 27 GFYLYRSVEEAMLRRSDVMVAGRVEHFRNLLRDNLTLAELKARPRLFENMLGNEQDILLL 86 Query: 89 RRQGEAPFINMNPDNLTPPAM 109 + GEAP + +NP + P++ Sbjct: 87 GQPGEAPIVAVNPRHERLPSL 107 >RSp0488 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 465 Score = 238 bits (607), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 128/272 (47%), Positives = 173/272 (63%), Gaps = 12/272 (4%) Query: 114 RMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSADLAHEIR 173 R+ R+AA + P+ L TRL E AP EL L ALNAML RL++G+ LSQFSADLAH+ R Sbjct: 200 RIGRQAASVVPSQLDTRLTLEGAPRELSDLLAALNAMLTRLQDGFARLSQFSADLAHDFR 259 Query: 174 TPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQLVVDRS 233 TP+ L+GQT+VTL R EY +LES+LEE RLSR+IE++LFLA+ DHA++ + + Sbjct: 260 TPLANLIGQTEVTLAHPRPAGEYRAVLESSLEEYARLSRMIEDMLFLARADHARVALSVA 319 Query: 234 AIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACS-----ANLVMWRRAVSNLVVNAV 288 +D R E+Q + DYFE VAA+RD+ +V C A+L + RRA++NL+ NA+ Sbjct: 320 PLDARHEIQVLVDYFEAVAADRDITIQV-------CGNGRVRADLTLLRRAINNLLDNAL 372 Query: 289 RYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGLG 348 R+ G I ++V+ AI V N G + + +FDRFYRGD +R+ S GLG Sbjct: 373 RHTPGGARIDVAVQVLPHSTAIAVRNPGPGIPAASLPLLFDRFYRGDPARANSERSAGLG 432 Query: 349 LAIVKAIMTVHGGTAAVACSADGWIAFSLRFP 380 LAIV+ IM +HGGTA + G F L FP Sbjct: 433 LAIVQTIMDLHGGTAQASSPPGGLTEFRLIFP 464 >ZybcZ [T] COG0642 Signal transduction histidine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 482 Score = 210 bits (535), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 112/275 (40%), Positives = 171/275 (62%), Gaps = 6/275 (2%) Query: 111 PAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSADLAH 170 P +SR+ IT +L RL + P EL QL + N M++R+E+ + S FSAD+AH Sbjct: 212 PIRSVSRQIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAH 271 Query: 171 EIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQLVV 230 EIRTP+ L+ QT++ L Q R+ +E E +L SNLEELTR+++++ ++LFLAQ D+ QL+ Sbjct: 272 EIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIP 331 Query: 231 DRSAIDLREELQKIADYFEGVAAER--DMQFEVDAAPGLACSANLVMWRRAVSNLVVNAV 288 ++ ++L +E+ K+ D+FE +A +R ++QF D + + +M RRA+SNL+ NA+ Sbjct: 332 EKKMLNLADEVGKVFDFFEALAEDRGVELQFVGDEC---QVAGDPLMLRRALSNLLSNAL 388 Query: 289 RYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGLG 348 RY G AI + + + + V N G + + + R+FDRFYR D SR E +G+G Sbjct: 389 RYTPPGEAIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIG 448 Query: 349 LAIVKAIMTVHGGTAAVACSADGWIAFSLRFPTRG 383 LAIVK+I+ H GT AV +A G F + P RG Sbjct: 449 LAIVKSIVVAHKGTVAVTSNARGT-RFVIVLPERG 482 >ECs0608 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 482 Score = 210 bits (535), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 112/275 (40%), Positives = 171/275 (62%), Gaps = 6/275 (2%) Query: 111 PAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSADLAH 170 P +SR+ IT +L RL + P EL QL + N M++R+E+ + S FSAD+AH Sbjct: 212 PIRSVSRQIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAH 271 Query: 171 EIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQLVV 230 EIRTP+ L+ QT++ L Q R+ +E E +L SNLEELTR+++++ ++LFLAQ D+ QL+ Sbjct: 272 EIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIP 331 Query: 231 DRSAIDLREELQKIADYFEGVAAER--DMQFEVDAAPGLACSANLVMWRRAVSNLVVNAV 288 ++ ++L +E+ K+ D+FE +A +R ++QF D + + +M RRA+SNL+ NA+ Sbjct: 332 EKKMLNLADEVGKVFDFFEALAEDRGVELQFVGDEC---QVAGDPLMLRRALSNLLSNAL 388 Query: 289 RYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGLG 348 RY G AI + + + + V N G + + + R+FDRFYR D SR E +G+G Sbjct: 389 RYTPPGEAIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIG 448 Query: 349 LAIVKAIMTVHGGTAAVACSADGWIAFSLRFPTRG 383 LAIVK+I+ H GT AV +A G F + P RG Sbjct: 449 LAIVKSIVVAHKGTVAVTSNARGT-RFVIVLPERG 482 >PA1438 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 481 Score = 204 bits (520), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 114/271 (42%), Positives = 164/271 (60%), Gaps = 5/271 (1%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 + P R+S A I+P LS RL+ PAELR+L GA N LDRLE Y L F+AD Sbjct: 191 GLWPVHRLSEEARRISPRQLSQRLQLSPLPAELRELVGAFNGALDRLEQAYVRLESFNAD 250 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 +AHE+RTP+ L+GQTQV L + R+ E YE++L+SNLEEL RL I+ ++LFLA+ D + Sbjct: 251 VAHELRTPLTNLIGQTQVALSRERSGEHYEEVLQSNLEELERLRAIVNDMLFLARADQGR 310 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDA-APGLACSANLVMWRRAVSNLVVN 286 L +R L E+ D+ E + E + EV A L A +++RAV+NL+ N Sbjct: 311 LACEREETSLAGEIATTVDFLEVIFDEAGVGIEVRGEARALVERA---LFQRAVTNLLYN 367 Query: 287 AVRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNG 346 A ++ AG +R+ V D + + V+N G+ + + +F+RFYR D +RS ++G Sbjct: 368 AAQHTAAGGTLRVGVERRGDEVRVAVSNPGVPIADEHRRHLFERFYRVDAARSNSEANHG 427 Query: 347 LGLAIVKAIMTVHGGTAAVACSADGWIAFSL 377 LGL+IVKA+ ++HGG+ V SADGW F Sbjct: 428 LGLSIVKAVASMHGGSVFVD-SADGWNTFGF 457