BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0059.p (332 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0650 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 432 e-121 PA0747 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 334 2e-91 PA3570 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 317 2e-86 BS_iolA [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 301 1e-81 RSc2536 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 300 2e-81 >RSp0650 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 515 Score = 432 bits (1111), Expect = e-121, Method: Compositional matrix adjust. Identities = 198/305 (64%), Positives = 247/305 (80%) Query: 7 PNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRNTS 66 P V L I GE V+S S EWR+V+NPATQEV+ARVPFAT++EVD A+ +A AF TW++T Sbjct: 20 PTVKLLIGGEFVESRSAEWREVVNPATQEVLARVPFATRDEVDAAIRSAHAAFATWKHTP 79 Query: 67 LAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLG 126 + RMRIMLK+Q L+R+++ +A +T E GKTLPDAEG++ RGLEVVEHACS+ SLQ G Sbjct: 80 VGARMRIMLKYQALIREHLPRIARTLTAEQGKTLPDAEGDIFRGLEVVEHACSVGSLQQG 139 Query: 127 ELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDPTS 186 E ENVAG VD YT+ QP+GV AGIT FNFP M+P +MFP+++ CGNTFVLKPSEQDP S Sbjct: 140 EFLENVAGAVDTYTLRQPLGVCAGITPFNFPAMIPLWMFPMAIVCGNTFVLKPSEQDPLS 199 Query: 187 SLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASEAG 246 ++ LVELA +AG+PPGVLNVVHGG EV + +C H +KAVSF+GST VGTH+YR A E G Sbjct: 200 TMLLVELALEAGVPPGVLNVVHGGKEVVDALCTHELVKAVSFVGSTAVGTHVYRLAGEHG 259 Query: 247 KRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIPEIV 306 KR Q MMGAKNH +VLPDA ++Q +N L+GAAFGAAGQRCMA SV VLVG ++W+PE+V Sbjct: 260 KRVQSMMGAKNHAVVLPDANREQTLNALVGAAFGAAGQRCMATSVAVLVGAAQQWVPELV 319 Query: 307 ERSKA 311 E+++A Sbjct: 320 EKARA 324 >PA0747 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 502 Score = 334 bits (856), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 159/300 (53%), Positives = 214/300 (71%) Query: 9 VPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRNTSLA 68 +P I+GE S S+E +V +PATQ+V+A P AT +E+++A+A+A+ AF+TWR Sbjct: 5 IPQLIDGEWRGSRSRELVEVTDPATQDVLALAPKATADEIEQAIASAQRAFETWREVPAP 64 Query: 69 QRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGEL 128 +R R+ML++Q LL+++ L E++ RE GK L DA+G+V RG+EVVEHA ++ SL +GE Sbjct: 65 ERARLMLRYQHLLKEHHDELGELLARETGKNLADAKGDVWRGIEVVEHAANVASLMMGET 124 Query: 129 AENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDPTSSL 188 ENVA +D + QP+GV AGIT FNFP M+P +MFP+++ACGNTFVLKPSEQDP + Sbjct: 125 VENVAREIDTASWIQPLGVCAGITPFNFPAMIPLWMFPLAIACGNTFVLKPSEQDPLTPN 184 Query: 189 FLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASEAGKR 248 L EL +AG P GVL V+HGG E + + HPDI+A+SF+GS VG H+YR + KR Sbjct: 185 RLAELFLEAGAPKGVLQVIHGGREQVDALLTHPDIRAISFVGSVAVGQHVYRTGTAHLKR 244 Query: 249 AQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIPEIVER 308 Q GAKNH ++LPDA K Q + NL+GA+ GAAGQRCMA S V VG +EWIPE+ ER Sbjct: 245 VQAFAGAKNHMVILPDANKAQVLGNLVGASCGAAGQRCMAISAAVFVGAAREWIPELAER 304 >PA3570 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 497 Score = 317 bits (813), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 150/293 (51%), Positives = 207/293 (70%) Query: 13 INGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRNTSLAQRMR 72 I G V+ + V NP +A + A+ E+V++AVA+A+E F +W+ T +++R R Sbjct: 9 IAGAFVEGLGAQRIPVSNPLDNSTLAEIACASAEQVEQAVASARETFASWKETPVSERAR 68 Query: 73 IMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGELAENV 132 +ML++Q LL+++ LA++++ E GKT DA+G+V RG+EVVEHAC++ SL +GE ENV Sbjct: 69 VMLRYQALLKEHHDELAKIVSSELGKTFEDAKGDVWRGIEVVEHACNVPSLLMGETVENV 128 Query: 133 AGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDPTSSLFLVE 192 A +D Y+I QP+GV GIT FNFP M+P +MFP+++ACGN F+LKPSEQ P +S+ L E Sbjct: 129 ARNIDTYSITQPLGVCVGITPFNFPAMIPLWMFPLAIACGNAFILKPSEQVPLTSVRLAE 188 Query: 193 LANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASEAGKRAQCM 252 L +AG P GVL VVHGG E + + HP +KAVSF+GS VG ++Y + KR Q Sbjct: 189 LFLEAGAPKGVLQVVHGGKEQVDQLLKHPQVKAVSFVGSVAVGQYVYHTGTAHNKRVQSF 248 Query: 253 MGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIPEI 305 GAKNH +++PDA K Q I+NL+GA+ GAAGQRCMA SV VLVG +EWIPEI Sbjct: 249 AGAKNHMVIMPDADKAQVISNLVGASVGAAGQRCMAISVAVLVGAAREWIPEI 301 >BS_iolA [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 487 Score = 301 bits (772), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 151/306 (49%), Positives = 209/306 (68%), Gaps = 1/306 (0%) Query: 4 ANIPNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWR 63 A I + YINGE V+S + ++ DV+NPAT+EV+ +VP +TKE++D A A EAFKTW Sbjct: 2 AEIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFKTWS 61 Query: 64 NTSLAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSL 123 ++ +R RI+ FQQLL + LA +IT E+GK +A GEV RG+E VE A SL Sbjct: 62 KVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALGEVGRGIENVEFAAGAPSL 121 Query: 124 QLGELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQD 183 +G+ ++A V+ PIGV GI FNFP+M+PC+MFP+++A GNTF+LKPSE+ Sbjct: 122 MMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSERT 181 Query: 184 PTSSLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRAS 243 P + LVEL KAGLP GV NVV+G +V N I +HP+IKA+SF+GS VG ++Y++ S Sbjct: 182 PLLTEKLVELFEKAGLPKGVFNVVYGAHDVVNGILEHPEIKAISFVGSKPVGEYVYKKGS 241 Query: 244 EAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVV-VLVGKTKEWI 302 E KR Q + GAKNH IVL DA + + N++GAAFG+AG+RCMA +VV V G E++ Sbjct: 242 ENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGIADEFM 301 Query: 303 PEIVER 308 ++ E+ Sbjct: 302 AKLQEK 307 >RSc2536 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 504 Score = 300 bits (769), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 150/304 (49%), Positives = 214/304 (70%), Gaps = 1/304 (0%) Query: 8 NVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRNTSL 67 +V YING + S ++DV NPA + RV A +EV++AVA AK AF W +T Sbjct: 10 DVGHYINGARLPGRSGRFQDVFNPAAGKAARRVALAEADEVNQAVAAAKAAFPAWADTPP 69 Query: 68 AQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGE 127 +R R++ +F QL+ ++ LA +IT EHGK DA+GEV RG++++E AC I L G+ Sbjct: 70 IRRARVLHRFLQLMNEHRDALAAIITAEHGKVFSDAQGEVARGIDIIEFACGIPQLLKGD 129 Query: 128 LAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDPTSS 187 + V+ G+D +T+ QP+GV AGIT FNFP M+PC+MFP+++A GNTFVLKPSE+DP++S Sbjct: 130 YTDQVSTGIDNWTMRQPLGVVAGITPFNFPCMVPCWMFPVAIAAGNTFVLKPSERDPSAS 189 Query: 188 LFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASEAGK 247 L + +L +AGLP GV NVV GG V + + DHPD++AVSF+GST + ++ +R +AGK Sbjct: 190 LLIADLLMRAGLPAGVFNVVQGGKPVVDTLLDHPDVQAVSFVGSTPIAAYVQQRGVQAGK 249 Query: 248 RAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWI-PEIV 306 R Q + GAKNH +V+PDA DQA++ L+GAA+G+AG+RCMA S+ VLVG + I P + Sbjct: 250 RVQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMATSIAVLVGDVADRIVPALA 309 Query: 307 ERSK 310 ER++ Sbjct: 310 ERAR 313