BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0059.p (420 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM2221 [GEPR] COG0477 Permeases of the major facilitator superf... 135 2e-31 PM1533 [GEPR] COG0477 Permeases of the major facilitator superfa... 131 3e-30 Zbcr [GEPR] COG0477 Permeases of the major facilitator superfami... 130 4e-30 ECs3074 [GEPR] COG0477 Permeases of the major facilitator superf... 130 4e-30 bcr [GEPR] COG0477 Permeases of the major facilitator superfamil... 129 1e-29 >STM2221 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 396 Score = 135 bits (339), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 110/378 (29%), Positives = 181/378 (47%), Gaps = 16/378 (4%) Query: 3 TTANHPRFLIFFIC-MLASAGQLAIDIYVPALPTMAQYFQTSAQAIQSSVTIYLMAYAFG 61 TT H F I FI +LA L+ID+Y+PALP ++ F A + Q +++ Y++ +A G Sbjct: 2 TTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPAGSAQMTLSTYILGFALG 61 Query: 62 QLFFGPLADAYGRKTMLILGLAMFTAGCLLTLAANNLETFILARCLQGFGIAATNLLAKA 121 QL +GP+AD+ GRK +++ G +F A + A ++ I+ R G AA +++ A Sbjct: 62 QLIYGPMADSLGRKPVILGGTLVFAAAAVACALAQTIDQLIVMRFFHGLAAAAASVVINA 121 Query: 122 IITDSFSGIALMHAFTYMAIAWGLAPILAPVIGAHLQTGFGWRSCLTFLLIYSF---VMW 178 ++ D + +++ + +AP++AP++G + W L I + VM Sbjct: 122 LMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWHYIFWILAIAAILASVM- 180 Query: 179 AVLSRYKETL----KQPVHLHPKTLLRNAGMVLRSPVFQSCFLAQGLCYSILLVFNIVGP 234 + + KETL +QP H+ +T + N + R S LA G ++ + F GP Sbjct: 181 -IFALIKETLPVERRQPFHI--RTTIGNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGP 237 Query: 235 FMVQETLHKPPTYFG-YLALAIGLMYFLGGISNRIHHPRLPTPEQRLRIGARVMTGAAVV 293 F+ E H PP FG Y AL I ++ + I++R R R G + AV Sbjct: 238 FVYIEINHVPPQDFGYYFALNIVFLFVMTIINSRF--VRRVGALNMFRAGLWIQFAMAVW 295 Query: 294 MLILALTVGLEVWTLTLPVLFMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGFALLLVS 353 M+ AL +G+ W L + V C + MA FPH+AG S++ G + Sbjct: 296 MVFSAL-MGIGFWALVVGVAAFVGCVSMVSSNAMAVILDEFPHMAGTASSLAGTFRFGIG 354 Query: 354 SLMMGLAGFVPFHSLTPM 371 +++ L F+S PM Sbjct: 355 AIVGALLSLATFNSAWPM 372 >PM1533 [GEPR] COG0477 Permeases of the major facilitator superfamily Pmu Pasteurella multocida Length = 399 Score = 131 bits (329), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 79/252 (31%), Positives = 127/252 (50%), Gaps = 4/252 (1%) Query: 2 NTTANHPRFLIFFICMLASAGQLAIDIYVPALPTMAQYFQTSAQAIQSSVTIYLMAYAFG 61 NTT N LI F+ L G L+ID+Y+P+LPT+A+ TS + +Q SV+ +L + G Sbjct: 6 NTTWNQTA-LICFLGTLVGFGPLSIDMYLPSLPTIAKALHTSIEWVQLSVSTFLTGFCVG 64 Query: 62 QLFFGPLADAYGRKTMLILGLAMFTAGCLLTLAANNLETFILARCLQGFGIAATNLLAKA 121 LF+GPL+D YGR+ +L++G+ ++ + A ++E ++AR LQ FG +L +A Sbjct: 65 MLFYGPLSDKYGRRIILLIGMTIYIVASIACSIATSIEQLLVARFLQAFGGGVGPVLGRA 124 Query: 122 IITDSFSGIALMHAFTYMAIAWGLAPILAPVIGAHLQTGFGWRSCLTFLLIYSFVMWAVL 181 I+ DSF + H + M + LAP+LAP IG + FGW + L + V W + Sbjct: 125 IVRDSFPPQRITHVLSMMQLVTMLAPLLAPFIGGIVLLWFGWETQFLLLALIGVVCWLIA 184 Query: 182 SRYKETLKQPVHLHP---KTLLRNAGMVLRSPVFQSCFLAQGLCYSILLVFNIVGPFMVQ 238 + Q H P T + +L+ P L + + + PF+ Sbjct: 185 YFFLAETNQDRHQRPLNLGTFFQAYCGILKQPQSFGNILCLSAMFGGMFAYVAGTPFVYI 244 Query: 239 ETLHKPPTYFGY 250 + H PP +G+ Sbjct: 245 DYFHIPPQDYGF 256 >Zbcr [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 396 Score = 130 bits (328), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 107/376 (28%), Positives = 180/376 (47%), Gaps = 12/376 (3%) Query: 3 TTANHPRFLIFFIC-MLASAGQLAIDIYVPALPTMAQYFQTSAQAIQSSVTIYLMAYAFG 61 TT H F I FI +LA L+ID+Y+PALP ++ F A + Q +++ Y++ +A G Sbjct: 2 TTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALG 61 Query: 62 QLFFGPLADAYGRKTMLILGLAMFTAGCLLTLAANNLETFILARCLQGFGIAATNLLAKA 121 QL +GP+AD++GRK +++ G +F A + A ++ I+ R G AA +++ A Sbjct: 62 QLIYGPMADSFGRKPVVLGGTLVFAAAAVACALAQTIDQLIVMRFFHGLAAAAASVVINA 121 Query: 122 IITDSFSGIALMHAFTYMAIAWGLAPILAPVIGAHLQTGFGWRSCLTFLLIYSFVMWA-V 180 ++ D + +++ + +AP++AP++G + W L + + + A + Sbjct: 122 LMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWHYIFWILAVAAILASAMI 181 Query: 181 LSRYKETL----KQPVHLHPKTLLRNAGMVLRSPVFQSCFLAQGLCYSILLVFNIVGPFM 236 KETL +QP H+ +T + N + R S LA G ++ + F GPF+ Sbjct: 182 FFLIKETLPPERRQPFHI--RTTIGNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGPFV 239 Query: 237 VQETLHKPPTYFG-YLALAIGLMYFLGGISNRIHHPRLPTPEQRLRIGARVMTGAAVVML 295 E H P FG Y AL I ++ + ++R R R G + A M+ Sbjct: 240 YIEINHVAPENFGYYFALNIVFLFVMTIFNSRF--VRRIGALNMFRSGLWIQFIMAAWMV 297 Query: 296 ILALTVGLEVWTLTLPVLFMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGFALLLVSSL 355 I AL +GL W+L + V C + MA FPH+AG S++ G + ++ Sbjct: 298 ISAL-LGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDEFPHMAGTASSLAGTFRFGIGAI 356 Query: 356 MMGLAGFVPFHSLTPM 371 + L F+S PM Sbjct: 357 VGALLSLATFNSAWPM 372 >ECs3074 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 396 Score = 130 bits (328), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 107/376 (28%), Positives = 180/376 (47%), Gaps = 12/376 (3%) Query: 3 TTANHPRFLIFFIC-MLASAGQLAIDIYVPALPTMAQYFQTSAQAIQSSVTIYLMAYAFG 61 TT H F I FI +LA L+ID+Y+PALP ++ F A + Q +++ Y++ +A G Sbjct: 2 TTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALG 61 Query: 62 QLFFGPLADAYGRKTMLILGLAMFTAGCLLTLAANNLETFILARCLQGFGIAATNLLAKA 121 QL +GP+AD++GRK +++ G +F A + A ++ I+ R G AA +++ A Sbjct: 62 QLIYGPMADSFGRKPVVLGGTLVFAAAAVACALAQTIDQLIVMRFFHGLAAAAASVVINA 121 Query: 122 IITDSFSGIALMHAFTYMAIAWGLAPILAPVIGAHLQTGFGWRSCLTFLLIYSFVMWA-V 180 ++ D + +++ + +AP++AP++G + W L + + + A + Sbjct: 122 LMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWHYIFWILAVAAILASAMI 181 Query: 181 LSRYKETL----KQPVHLHPKTLLRNAGMVLRSPVFQSCFLAQGLCYSILLVFNIVGPFM 236 KETL +QP H+ +T + N + R S LA G ++ + F GPF+ Sbjct: 182 FFLIKETLPPERRQPFHI--RTTIGNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGPFV 239 Query: 237 VQETLHKPPTYFG-YLALAIGLMYFLGGISNRIHHPRLPTPEQRLRIGARVMTGAAVVML 295 E H P FG Y AL I ++ + ++R R R G + A M+ Sbjct: 240 YIEINHVAPENFGYYFALNIVFLFVMTIFNSRF--VRRIGALNMFRSGLWIQFIMAAWMV 297 Query: 296 ILALTVGLEVWTLTLPVLFMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGFALLLVSSL 355 I AL +GL W+L + V C + MA FPH+AG S++ G + ++ Sbjct: 298 ISAL-LGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDEFPHMAGTASSLAGTFRFGIGAI 356 Query: 356 MMGLAGFVPFHSLTPM 371 + L F+S PM Sbjct: 357 VGALLSLATFNSAWPM 372 >bcr [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 396 Score = 129 bits (324), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 107/386 (27%), Positives = 179/386 (46%), Gaps = 32/386 (8%) Query: 3 TTANHPRFLIFFIC-MLASAGQLAIDIYVPALPTMAQYFQTSAQAIQSSVTIYLMAYAFG 61 TT H F I FI +LA L+ID+Y+PALP ++ F A + Q +++ Y++ +A G Sbjct: 2 TTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALG 61 Query: 62 QLFFGPLADAYGRKTMLILGLAMFTAGCLLTLAANNLETFILARCLQGFGIAATNLLAKA 121 QL +GP+AD++GRK +++ G +F A + AN ++ I+ R G AA +++ A Sbjct: 62 QLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLIVMRFFHGLAAAAASVVINA 121 Query: 122 IITDSFSGIALMHAFTYMAIAWGLAPILAPVIGAHLQTGFGWRSCLTFLLIYSFVMWA-- 179 ++ D + +++ + +AP++AP++G + W ++ W Sbjct: 122 LMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWH----------YIFWILA 171 Query: 180 ---------VLSRYKETL----KQPVHLHPKTLLRNAGMVLRSPVFQSCFLAQGLCYSIL 226 + KETL +QP H+ +T + N + R S LA G ++ + Sbjct: 172 LAAILASAMIFFLIKETLPPERRQPFHI--RTTIGNFAALFRHKRVLSYMLASGFSFAGM 229 Query: 227 LVFNIVGPFMVQETLHKPPTYFG-YLALAIGLMYFLGGISNRIHHPRLPTPEQRLRIGAR 285 F GPF+ E H P FG Y AL I ++ + ++R R R G Sbjct: 230 FSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRF--VRRIGALNMFRSGLW 287 Query: 286 VMTGAAVVMLILALTVGLEVWTLTLPVLFMAFCAGAMYPTLMAKGNSIFPHIAGLTSAIL 345 + A M+I AL +GL W+L + V C + MA FPH+AG S++ Sbjct: 288 IQFIMAAWMVISAL-LGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDEFPHMAGTASSLA 346 Query: 346 GFALLLVSSLMMGLAGFVPFHSLTPM 371 G + +++ L F+S PM Sbjct: 347 GTFRFGIGAIVGALLSLATFNSAWPM 372