BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0058.p (770 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0978 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 1071 0.0 NMA1802 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 826 0.0 NMB1605 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 820 0.0 parC [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, top... 613 e-175 ZparC [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, to... 613 e-175 >RSc0978 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Rso Ralstonia solanacearum Length = 781 Score = 1071 bits (2770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/767 (69%), Positives = 624/767 (81%), Gaps = 8/767 (1%) Query: 3 EQANLFEQPAPPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNE 62 EQ ++ P P E+LTL+ +AERAYLDYA+SVVKGRALP+VADGQKPVQRRIL+AM+E Sbjct: 2 EQQDILFDPREP-AEALTLAHYAERAYLDYAVSVVKGRALPEVADGQKPVQRRILFAMHE 60 Query: 63 LGLNATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDG 122 +GL A AKP KSA VVGDVLGK HPHGDQS YDALVR+AQDFSLRYPLIDGQGNFGSRDG Sbjct: 61 MGLRADAKPVKSARVVGDVLGKYHPHGDQSAYDALVRLAQDFSLRYPLIDGQGNFGSRDG 120 Query: 123 DGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGI 182 DGAAAMRYTEARLTPIS+LLL+E+D GTVDF PNYDGS +EP+LLPARLPF+LLNGASGI Sbjct: 121 DGAAAMRYTEARLTPISRLLLEELDQGTVDFIPNYDGSMDEPRLLPARLPFVLLNGASGI 180 Query: 183 AVGMATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIY 242 AVGMATEIPSHNLREVA AAVA+IR+ K+T +LM ++ GPDFPGGGQII+ + IA+IY Sbjct: 181 AVGMATEIPSHNLREVATAAVALIRDDKLTSTDLMQYMPGPDFPGGGQIISSAADIAQIY 240 Query: 243 QSGRGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKTLTP 302 ++GRGSLKVRARWKIED+ARGQWQ V+TELPP SSQKVLEEIEELTNPK++ GKK+LTP Sbjct: 241 ETGRGSLKVRARWKIEDLARGQWQLVVTELPPNTSSQKVLEEIEELTNPKVRAGKKSLTP 300 Query: 303 EQQAQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINL 362 EQ KQ++L +LDAVRDESG++APVRLVFEPKSKN Q EF N LLA TSLE+ ++INL Sbjct: 301 EQLQLKQTLLGLLDAVRDESGKDAPVRLVFEPKSKNIGQQEFANALLAHTSLESGAAINL 360 Query: 363 VMIGGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKV 422 VMIG DGRPRQKGL +IL EWI +RF T+TRR++ +L KVEDRIHILEGR+ +LLNID+V Sbjct: 361 VMIGTDGRPRQKGLREILREWIDYRFATVTRRTRHRLGKVEDRIHILEGRQLVLLNIDEV 420 Query: 423 IRIIRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQD 482 IRIIRESDEPKPAL++AF LS+RQAEDILEIRLRQLARLE IKI+QEL +LR E+A L Sbjct: 421 IRIIRESDEPKPALMQAFGLSERQAEDILEIRLRQLARLEAIKIEQELKDLREEQAELDV 480 Query: 483 LLDNPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGWVRA 542 LL + M+R ++KEIE D KQFGD RRT+I+E +A E KV+DEPVTVI+SQKGWVR Sbjct: 481 LLKSETMMRRRIVKEIETDAKQFGDDRRTLIQEERRAAAEVKVVDEPVTVIVSQKGWVRT 540 Query: 543 RGGHGHDATQFTFKAGDGLYGAFECRTVDNLLGFGS-----NGRIYTVGVNSLPNARGDG 597 R GHGHDATQF FKAGD LY FECRT D LL FG+ GR+Y+V V +LP RGDG Sbjct: 541 RQGHGHDATQFGFKAGDTLYDTFECRTTDALLIFGTRDDKGTGRVYSVAVANLPGGRGDG 600 Query: 598 VPITTLVDLGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEG 657 VP+TTL++L G ++ H A + +L+++ G GF AKVGDM+ R KGGKAF+TLDEG Sbjct: 601 VPLTTLIELAPGTHIAHTLASHAEQNVLISTQGGNGFLAKVGDMVGRQKGGKAFLTLDEG 660 Query: 658 DLPLAPRPMPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAI 717 D P P +P A ACLS GRLL+F L E+KTLASGGRGVILMELEKNE L A A Sbjct: 661 DQPNKPAAVPEDAYGAACLSANGRLLLFPLAEVKTLASGGRGVILMELEKNETLAQALAF 720 Query: 718 TQKGVLVSGTG-RGGKAQDVTLSAV-ALALHIGKRARKGKALESKLK 762 G +VSG G R GKA + T + A + GKRARKG+A+E KL+ Sbjct: 721 GPAGFVVSGAGPRSGKATEQTFTTTRAQEPYAGKRARKGRAIEPKLR 767 >NMA1802 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit NmA Neisseria meningitidis Z2491 Length = 765 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/755 (55%), Positives = 542/755 (71%), Gaps = 11/755 (1%) Query: 10 QPAPP--DGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNELGLNA 67 QP P D +L L +AERAYL+YA+SVVKGRALP+V+DGQKPVQRRIL+AM ++GL A Sbjct: 2 QPHAPHTDSNTLMLGRYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILFAMRDMGLTA 61 Query: 68 TAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDGDGAAA 127 AKP KSA VVG++LGK HPHGD S Y+A+VRMAQDF+LRYPLIDG GNFGSRDGDGAAA Sbjct: 62 GAKPVKSARVVGEILGKYHPHGDSSAYEAMVRMAQDFTLRYPLIDGIGNFGSRDGDGAAA 121 Query: 128 MRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGIAVGMA 187 MRYTEARLTPI++LLL EI+ GTVDF PNYDG+ +EP LPARLP +LLNGASGIAVGMA Sbjct: 122 MRYTEARLTPIAELLLSEINQGTVDFVPNYDGAFDEPLHLPARLPMVLLNGASGIAVGMA 181 Query: 188 TEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIYQSGRG 247 TEIPSHNL EV +AA+A+++ P + A+LM +I PDF GGGQIITP + IY++G+G Sbjct: 182 TEIPSHNLNEVTQAAIALLKKPTLETADLMQYIPAPDFAGGGQIITPADELRRIYETGKG 241 Query: 248 SLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKTLTPEQQAQ 307 S++VRAR++IE +ARGQW+ ++TELPP +S K+L EIEE TNPK K GKK L +Q Sbjct: 242 SVRVRARYEIEKLARGQWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDQLNT 301 Query: 308 KQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINLVMIGG 367 K+ +L ++D VRDES E PVRLVFEPKS D F+NTL+AQTSLE + S+NLVM+G Sbjct: 302 KKLMLDLIDRVRDESDGEHPVRLVFEPKSSRIDTDTFINTLMAQTSLEGNVSMNLVMMGL 361 Query: 368 DGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKVIRIIR 427 D RP QK L IL EW+ FR VT+TRR +F+L +VE R+HILEGR + L+ID+VI++IR Sbjct: 362 DNRPAQKNLKTILQEWLDFRTVTVTRRLKFRLNQVEKRLHILEGRLKVFLHIDEVIKVIR 421 Query: 428 ESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQDLLDNP 487 ESD+PK L+ AF L++ QAEDILEIRLRQLARLE K+++EL ELR E+ L LL + Sbjct: 422 ESDDPKTDLMAAFGLTEIQAEDILEIRLRQLARLEGFKLEKELNELREEQGRLNILLGDE 481 Query: 488 ASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGWVRARGGHG 547 ++L++KE++AD KQFGDARRT++EEA +AVL Q DEP+T+I+S+KGW+R+R GH Sbjct: 482 NEKRKLIVKEMQADMKQFGDARRTLVEEAGRAVLTQTTADEPITLILSEKGWIRSRAGHN 541 Query: 548 HDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVPITTLVDLG 607 D +Q FK GD L E RT+ ++ S+GR YT+ +P RGDGVP+++L++L Sbjct: 542 LDLSQTAFKEGDRLKQTLEGRTILPVVILDSSGRTYTLDAAEIPGGRGDGVPVSSLIELQ 601 Query: 608 NGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDLPLAPRPMP 667 NG + G + LL+S GYGF AK+GDM+ RVK GK +T D G+ L P + Sbjct: 602 NGAKPVAMLTGLPEQHYLLSSSGGYGFIAKLGDMVGRVKAGKVVMTADSGETVLPPVAVY 661 Query: 668 AGA-----SAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQKGV 722 A + I + Q R L F + E+K +A G+G+ ++ L E + ++ + Sbjct: 662 ASSFINPDCKIIAATNQNRALAFPIGELKIMAK-GKGLQIIGLNAGESMTHTAVSSEPEI 720 Query: 723 LVSGTGRGGKAQDVTLSAVALALHIGKRARKGKAL 757 L+ GR G A + ++L KR +KGK L Sbjct: 721 LIESEGRRGAAHK---DRIPISLLEAKRGKKGKLL 752 >NMB1605 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Nme Neisseria meningitidis MC58 Length = 767 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/748 (54%), Positives = 538/748 (71%), Gaps = 9/748 (1%) Query: 15 DGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNELGLNATAKPRKS 74 D +L L +AERAYL+YA+SVVKGRALP+V+DGQKPVQRRIL+AM ++GL A AKP KS Sbjct: 11 DSNTLMLGRYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILFAMRDMGLTAGAKPVKS 70 Query: 75 AAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDGDGAAAMRYTEAR 134 A VVG++LGK HPHGD S Y+A+VRMAQDF+LRYPLIDG GNFGSRDGDGAAAMRYTEAR Sbjct: 71 ARVVGEILGKYHPHGDSSAYEAMVRMAQDFTLRYPLIDGIGNFGSRDGDGAAAMRYTEAR 130 Query: 135 LTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGIAVGMATEIPSHN 194 LTPI++LLL EI+ GTVDF PNYDG+ +EP LPARLP +LLNGASGIAVGMATEIP HN Sbjct: 131 LTPIAELLLSEINQGTVDFVPNYDGAFDEPLHLPARLPMVLLNGASGIAVGMATEIPPHN 190 Query: 195 LREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIYQSGRGSLKVRAR 254 L EV +AA+A+++ P + A+LM +I PDF GGGQIITP + IY++G+GS++VRAR Sbjct: 191 LNEVTQAAIALLKKPTLETADLMQYIPAPDFAGGGQIITPADELRRIYETGKGSVRVRAR 250 Query: 255 WKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKTLTPEQQAQKQSILAM 314 ++IE +ARGQW+ ++TELPP +S K+L EIEE TNPK K GKK L +Q K+ +L + Sbjct: 251 YEIEKLARGQWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDQLNTKKLMLDL 310 Query: 315 LDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINLVMIGGDGRPRQK 374 +D VRDES E PVRLVFEPKS D F+NTL+AQTSLE + S+NLVM+G D RP QK Sbjct: 311 IDRVRDESDGEHPVRLVFEPKSSRIDTDTFINTLMAQTSLEGNVSMNLVMMGLDNRPAQK 370 Query: 375 GLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKVIRIIRESDEPKP 434 L IL EW+ FR VT+TRR +F+L +VE R+HILEGR + L+ID+VI++IRESD+PK Sbjct: 371 NLKTILQEWLDFRTVTVTRRLKFRLNQVEKRLHILEGRLKVFLHIDEVIKVIRESDDPKA 430 Query: 435 ALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQDLLDNPASMKRLV 494 L+ AF L++ QAEDILEIRLRQLARLE K+++EL ELR E+ L LL + ++L+ Sbjct: 431 DLMAAFGLTEIQAEDILEIRLRQLARLEGFKLEKELNELREEQGRLNILLSDENEKRKLI 490 Query: 495 IKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGWVRARGGHGHDATQFT 554 +KE++AD KQ+GDARRT++EEA +AVL Q DEP+T+I+S+KGW+R+R GH D +Q Sbjct: 491 VKEMQADMKQYGDARRTLVEEAGRAVLTQTTADEPITLILSEKGWIRSRAGHNLDLSQTA 550 Query: 555 FKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVPITTLVDLGNGNNLLH 614 FK GD L E RTV ++ S+GR YT+ +P RGDGVP+++L++L NG + Sbjct: 551 FKEGDCLKQTLEGRTVLPVVILDSSGRTYTLDAAEIPGGRGDGVPVSSLIELQNGAKPVA 610 Query: 615 YFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDLPLAPRPMPAGA---- 670 G + LL+S +GYGF K+GDM+ RVK GK +T D G+ L P + A + Sbjct: 611 MLTGLPEQHYLLSSSSGYGFITKLGDMVGRVKAGKVVMTADSGETVLPPVAVYASSFINP 670 Query: 671 -SAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQKGVLVSGTGR 729 I + Q R L F + E+K +A G+G+ ++ L E + ++ +L+ GR Sbjct: 671 DCKIIAATSQNRALAFPIGELKIMAK-GKGLQIIGLNAGESMTHTAVSSELEILIESEGR 729 Query: 730 GGKAQDVTLSAVALALHIGKRARKGKAL 757 G A + ++L KR +KG+ L Sbjct: 730 RGAAHK---DRIPISLLEAKRGKKGRLL 754 >parC [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Eco Escherichia coli K12 Length = 752 Score = 613 bits (1580), Expect = e-175, Method: Compositional matrix adjust. Identities = 341/744 (45%), Positives = 466/744 (62%), Gaps = 46/744 (6%) Query: 16 GESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNELGLNATAKPRKSA 75 E L L F E AYL+Y++ V+ RALP + DG KPVQRRI+YAM+ELGLNA+AK +KSA Sbjct: 5 AERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 Query: 76 AVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDGDGA-AAMRYTEAR 134 VGDVLGK HPHGD + Y+A+V MAQ FS RYPL+DGQGN+G+ D + AAMRYTE+R Sbjct: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESR 124 Query: 135 LTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGIAVGMATEIPSHN 194 L+ S+LLL E+ GT D+ PN+DG+ +EPK+LPARLP +LLNG +GIAVGMAT+IP HN Sbjct: 125 LSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHN 184 Query: 195 LREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIYQSGRGSLKVRAR 254 LREVA+AA+A+I PK T +L+ + GPD+P +IIT + I +IY++GRGS+++RA Sbjct: 185 LREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV 244 Query: 255 WKIEDMARGQWQAVITELPPGVSSQKVLEEIE-ELTNPKIKLGKKTLTPEQQAQKQSILA 313 WK ED A VI+ LP VS +VLE+I ++ N K L Sbjct: 245 WKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKK-------------------LP 280 Query: 314 MLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINLVMIGGDGRPRQ 373 M+D +RDES E P RLV P+S D + MN L A T LE S INL MIG DGRP Sbjct: 281 MVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAV 340 Query: 374 KGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKVIRIIRESDEPK 433 K L +IL EW+ FR T+ RR ++L+KV R+HILEG LNID+VI IIR DEPK Sbjct: 341 KNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK 400 Query: 434 PALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQDLLDNPASMKRL 493 PAL+ F L++ QAE ILE++LR LA+LE +KI+ E +EL E+ LQ +L + M L Sbjct: 401 PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNL 460 Query: 494 VIKEIEADDKQFGDARRTVIEEAE--KAVLEQKVI-DEPVTVIISQKGWVRARGGHGHDA 550 + KE++AD + +GD RR+ ++E E KA+ E ++ EPVT+++SQ GWVR+ GH DA Sbjct: 461 LKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDA 520 Query: 551 TQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVPITTLVDLGNGN 610 +KAGD A + ++ ++ S GR Y + +LP+ARG G P+T + L G Sbjct: 521 PGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGA 580 Query: 611 NLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDLPLAPRPMPAGA 670 + H D ++L+ASDAGYGF D+++R + GKA ITL E + P + + Sbjct: 581 TVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS 640 Query: 671 SAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQKGVLVSGTGRG 730 + ++ GR+L+F + ++ L S G+G ++ + E + G Sbjct: 641 DMLLAITQAGRMLMFPVSDLPQL-SKGKGNKIINIPSAE---------------AARGED 684 Query: 731 GKAQDVTLSAVA-LALHIGKRARK 753 G AQ L + L +H+GKR K Sbjct: 685 GLAQLYVLPPQSTLTIHVGKRKIK 708 >ZparC [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit EcZ Escherichia coli O157:H7 EDL933 Length = 752 Score = 613 bits (1580), Expect = e-175, Method: Compositional matrix adjust. Identities = 341/744 (45%), Positives = 466/744 (62%), Gaps = 46/744 (6%) Query: 16 GESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNELGLNATAKPRKSA 75 E L L F E AYL+Y++ V+ RALP + DG KPVQRRI+YAM+ELGLNA+AK +KSA Sbjct: 5 AERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 Query: 76 AVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDGDGA-AAMRYTEAR 134 VGDVLGK HPHGD + Y+A+V MAQ FS RYPL+DGQGN+G+ D + AAMRYTE+R Sbjct: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESR 124 Query: 135 LTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGIAVGMATEIPSHN 194 L+ S+LLL E+ GT D+ PN+DG+ +EPK+LPARLP +LLNG +GIAVGMAT+IP HN Sbjct: 125 LSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHN 184 Query: 195 LREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIYQSGRGSLKVRAR 254 LREVA+AA+A+I PK T +L+ + GPD+P +IIT + I +IY++GRGS+++RA Sbjct: 185 LREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV 244 Query: 255 WKIEDMARGQWQAVITELPPGVSSQKVLEEIE-ELTNPKIKLGKKTLTPEQQAQKQSILA 313 WK ED A VI+ LP VS +VLE+I ++ N K L Sbjct: 245 WKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKK-------------------LP 280 Query: 314 MLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINLVMIGGDGRPRQ 373 M+D +RDES E P RLV P+S D + MN L A T LE S INL MIG DGRP Sbjct: 281 MVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAV 340 Query: 374 KGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKVIRIIRESDEPK 433 K L +IL EW+ FR T+ RR ++L+KV R+HILEG LNID+VI IIR DEPK Sbjct: 341 KNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK 400 Query: 434 PALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQDLLDNPASMKRL 493 PAL+ F L++ QAE ILE++LR LA+LE +KI+ E +EL E+ LQ +L + M L Sbjct: 401 PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNL 460 Query: 494 VIKEIEADDKQFGDARRTVIEEAE--KAVLEQKVI-DEPVTVIISQKGWVRARGGHGHDA 550 + KE++AD + +GD RR+ ++E E KA+ E ++ EPVT+++SQ GWVR+ GH DA Sbjct: 461 LKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDA 520 Query: 551 TQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVPITTLVDLGNGN 610 +KAGD A + ++ ++ S GR Y + +LP+ARG G P+T + L G Sbjct: 521 PGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGA 580 Query: 611 NLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDLPLAPRPMPAGA 670 + H D ++L+ASDAGYGF D+++R + GKA ITL E + P + + Sbjct: 581 TVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS 640 Query: 671 SAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQKGVLVSGTGRG 730 + ++ GR+L+F + ++ L S G+G ++ + E + G Sbjct: 641 DMLLAITQAGRMLMFPVSDLPQL-SKGKGNKIINIPSAE---------------AARGED 684 Query: 731 GKAQDVTLSAVA-LALHIGKRARK 753 G AQ L + L +H+GKR K Sbjct: 685 GLAQLYVLPPQSTLTIHVGKRKIK 708