BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0043.p (443 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 281 2e-75 VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibr... 275 1e-73 VCA0719 [T] COG0642 Signal transduction histidine kinase Vch Vib... 253 6e-67 PA2882 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 221 2e-57 alr0642 [T] COG0642 Signal transduction histidine kinase Nos Nos... 212 2e-54 >PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 470 Score = 281 bits (720), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 152/295 (51%), Positives = 205/295 (69%), Gaps = 16/295 (5%) Query: 149 MEEALQR----TGEEQRSL---INKLKEAQEQLLQSEKMASIGQLAAGVAHEINNPVGFV 201 ME A+Q G+ + +L I + KE + QL+Q+EK+ASIG LAAGVAHEINNP+ +V Sbjct: 168 MEAAIQEITREVGQAKEALEKEIGERKELESQLVQTEKLASIGHLAAGVAHEINNPISYV 227 Query: 202 SSNMKSLQTYVDQLLEVIVRQD---ALLSDDSLGEDLRQQARQLSASADLAYLKGDVVEL 258 SSN +L+ +V +LLEV+ + + D++L L Q L +LA++K DV L Sbjct: 228 SSNYTTLEEHVRRLLEVLEAYEEARPAIRDEALARRLEQ----LGERVELAFVKEDVAVL 283 Query: 259 ITESLEGLKRVKDIVQSLKDFSHV-GESDWQMVDIRKGLESTITIANNELKYKTVIERQY 317 + ES EG+ RV+ IVQ LK+FS V E DWQ D+ +G+EST+ I +ELKY+ + R+Y Sbjct: 284 LRESREGIGRVRKIVQDLKNFSRVDAEDDWQWTDLHQGIESTLNIVASELKYRADVVREY 343 Query: 318 GELPLIKGLASQLNQVFMNLLVNAAHSFA-ERGTIRIRTECKEDWVYIQVEDTGCGIPPE 376 G+LP +K L SQ+NQV MNL++NAA + ERG I IRT + +I+VED+G GI PE Sbjct: 344 GDLPEVKCLPSQINQVVMNLVMNAAQAMGPERGRIVIRTGHTVEHAWIEVEDSGQGISPE 403 Query: 377 NLSRIFEPFFTTKPIGSGTGLGLSLSYGIVQKHGGRIDVQSEVGVGTCFTVCLPV 431 L RIF+PFFTTKP+G GTGLGLSLSYGIVQKHGG I+V+S+ GVG+ F + LP+ Sbjct: 404 ILPRIFDPFFTTKPVGKGTGLGLSLSYGIVQKHGGTIEVRSQPGVGSAFRIVLPL 458 >VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 439 Score = 275 bits (704), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 143/291 (49%), Positives = 197/291 (67%), Gaps = 7/291 (2%) Query: 145 ERKLMEEALQRTGEEQRSLINKLKEAQEQLLQSEKMASIGQLAAGVAHEINNPVGFVSSN 204 E K + + L+ + Q+ LI KL++AQ QL+QSEKMASIGQL+AG+AHEINNPVGF++SN Sbjct: 137 ELKRVSQKLEEEHQSQKVLIKKLEDAQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSN 196 Query: 205 MKSLQTYVDQLLEVI--VRQDALLSDDSLGEDLRQQARQLSASADLAYLKGDVVELITES 262 +++L Y + L +V+ + Q S D+ L + +++ + ++ D ELITES Sbjct: 197 LQTLSDYFNSLEKVLKSITQTIGQSKDTA---LNEACQKILKQGQVDFILEDTAELITES 253 Query: 263 LEGLKRVKDIVQSLKDFSHVGESDWQMVDIRKGLESTITIANNELKYKTVIERQYG-ELP 321 LEG RV IV++LK+FSHV S+W ++ +EST+ I NNE+KY +E+ Y +P Sbjct: 254 LEGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKYNITLEKHYAANVP 313 Query: 322 LIKGLASQLNQVFMNLLVNAAHSFAERGTIRIRTECK-EDWVYIQVEDTGCGIPPENLSR 380 + Q+NQV +N+LVNA+H+ GTI I + +D+V I + DTGCGIP E R Sbjct: 314 DVFCQPMQINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIRDTGCGIPEEIRER 373 Query: 381 IFEPFFTTKPIGSGTGLGLSLSYGIVQKHGGRIDVQSEVGVGTCFTVCLPV 431 IFEPFFTTKP+GSGTGLGLS+SYGI+ KH G I V SEVG G+ FT+ LPV Sbjct: 374 IFEPFFTTKPVGSGTGLGLSVSYGIINKHNGTISVTSEVGKGSEFTIRLPV 424 >VCA0719 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 315 Score = 253 bits (646), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 138/298 (46%), Positives = 191/298 (64%), Gaps = 13/298 (4%) Query: 143 ITERKLMEE---ALQRTGEEQRSLINKLKEAQEQLLQSEKMASIGQLAAGVAHEINNPVG 199 I KL+EE AL E +S + +L AQ QLLQSEKMAS+GQLAAGVAHEINNP+G Sbjct: 19 ILAEKLLEEKSRALYDKVLELQSTLEQLNGAQAQLLQSEKMASVGQLAAGVAHEINNPIG 78 Query: 200 FVSSNMKSLQTYVDQLLEV--IVRQDALLSDDSLGEDLRQQARQLSASADLAYLKGDVVE 257 F SN+ +L+ Y + ++ V Q A + G + Q + DLA+++ DV+ Sbjct: 79 FCLSNLNTLRDYAEVFAQLADFVEQSAPSFE---GSEFYQAWMRFKQQHDLAFVREDVLS 135 Query: 258 LITESLEGLKRVKDIVQSLKDFSHVGESDWQMVDIRKGLESTITIANNELKYKTVIERQY 317 L+ ES GL RVKDIV SL+ SH + + ++ +ES + I N+ KY +++RQ Sbjct: 136 LVEESASGLHRVKDIVTSLQSVSHSSDGRFAECNLNDCIESALRIVWNQFKYTMLVDRQL 195 Query: 318 GE-LPLIKGLASQLNQVFMNLLVNAAHSFAERGTIRIRT----ECKEDWVYIQVEDTGCG 372 E LP IKG+A ++ QV MN+ +NA+H+ E G + I T E + WV +Q+ D G G Sbjct: 196 AENLPKIKGIAPEIQQVLMNMFINASHACDEHGELTITTDTLNEKGKAWVQVQIADNGHG 255 Query: 373 IPPENLSRIFEPFFTTKPIGSGTGLGLSLSYGIVQKHGGRIDVQSEVGVGTCFTVCLP 430 I PE+L++IF+PFFTTKP+G GTGLGLS+++GIV+KH G+I V SEVG GT FT+ P Sbjct: 256 ISPEHLAKIFDPFFTTKPVGVGTGLGLSIAFGIVEKHQGKISVTSEVGQGTRFTLLFP 313 >PA2882 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 371 Score = 221 bits (564), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 124/297 (41%), Positives = 178/297 (59%), Gaps = 7/297 (2%) Query: 147 KLMEEALQRTGEEQRSLINKLKEAQEQLLQSEKMASIGQLAAGVAHEINNPVGFVSSNMK 206 K ME + + R + LKE+Q QL+QSEKMAS+GQ+ AGVAHE+N P+G+V +N+ Sbjct: 70 KAMEARIAQRNRVLRKALVDLKESQAQLVQSEKMASLGQMVAGVAHELNTPLGYVGNNLA 129 Query: 207 SLQTYVDQLLEVIVRQDALL-------SDDSLGEDLRQQARQLSASADLAYLKGDVVELI 259 L+ D LL + Q AL+ D++ Q A + A + L+ D+ +L Sbjct: 130 LLEELSDPLLRLADAQAALVDCLGDPQCDEARLAQALQAADAVRREAAVEQLREDLRQLF 189 Query: 260 TESLEGLKRVKDIVQSLKDFSHVGESDWQMVDIRKGLESTITIANNELKYKTVIERQYGE 319 ++ GL ++ ++V LKDF+ + + + VD+ + + + IA +K K I Q GE Sbjct: 190 VDTRYGLGQIGELVSGLKDFARLDRAFSEEVDLNDCVRNAVLIARTAIKDKAEISSQLGE 249 Query: 320 LPLIKGLASQLNQVFMNLLVNAAHSFAERGTIRIRTECKEDWVYIQVEDTGCGIPPENLS 379 LPLI SQ+NQV +NLL NAA + G I +++ E V++ V+D G G+P E L Sbjct: 250 LPLIACAPSQINQVLLNLLTNAAQAMERFGRILLKSWADERQVFLSVQDNGKGMPAEVLG 309 Query: 380 RIFEPFFTTKPIGSGTGLGLSLSYGIVQKHGGRIDVQSEVGVGTCFTVCLPVTQIKE 436 RIF+PFFTTKP+G GTGLGLS+SY I+Q+HGG I V SE G GT F + LP Q +E Sbjct: 310 RIFDPFFTTKPVGQGTGLGLSISYKIIQQHGGTIRVASEPGRGTRFLISLPREQARE 366 >alr0642 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 735 Score = 212 bits (539), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 120/311 (38%), Positives = 187/311 (60%), Gaps = 28/311 (9%) Query: 144 TERKLMEEALQRTGEEQRSLINKLKEAQEQLLQSEKMASIGQLAAGVAHEINNPVGFVSS 203 T + +E+ +++ + ++ + +L+ Q Q++Q EKM+S+GQL AGVAHEINNPV F+ Sbjct: 426 TSKAELEDRVEQRTADLKTALTELQRTQAQVIQGEKMSSLGQLVAGVAHEINNPVNFIYG 485 Query: 204 NMKSLQTYVDQLLEVI-VRQDALLSDDSLGEDLRQQARQLSASADLAYLKGDVVELITES 262 N+ L Y LL +I + Q+ SDD + + L+ DL +L D+ ++++ Sbjct: 486 NITHLNAYTQDLLRMIHLYQERHPSDDP-------EVQALATEIDLDFLVEDLQKMLSSM 538 Query: 263 LEGLKRVKDIVQSLKDFSHVGESDWQMVDIRKGLESTITIANNELK---YKTVIE--RQY 317 G +R++ IV SL++FS + E++++ VDI +G+EST+ I + LK K IE R Y Sbjct: 539 NMGTERIRSIVLSLRNFSRIDEAEFKAVDIHEGIESTLLILQHRLKDQPDKPAIEVIRDY 598 Query: 318 GELPLIKGLASQLNQVFMNLLVNAAHSFAERGTIRIRTECKED--------------WVY 363 G LPLI+ A QLNQV MN+LVNA + E R E K + W+ Sbjct: 599 GNLPLIECYAGQLNQVLMNILVNAIDALDELNIKRTYEEIKANPSQITIRTSVNDAQWME 658 Query: 364 IQVEDTGCGIPPENLSRIFEPFFTTKPIGSGTGLGLSLSYGIV-QKHGGRIDVQSEVGVG 422 I + D G GIP + +RIF+PFFTTKP+G GTG+G+++SY I+ +KH G+++ S VG G Sbjct: 659 IAIADNGPGIPEQLKNRIFDPFFTTKPVGKGTGMGMAISYQIITEKHSGKLECFSTVGQG 718 Query: 423 TCFTVCLPVTQ 433 + F + +P+ Q Sbjct: 719 SEFRIQVPIRQ 729