BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0034.p (571 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 309 1e-83 VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibr... 283 6e-76 alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nos... 231 3e-60 alr4716_2 [T] COG0642 Signal transduction histidine kinase Nos N... 224 3e-58 alr4879_2 [T] COG0642 Signal transduction histidine kinase Nos N... 224 4e-58 >PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 470 Score = 309 bits (791), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 155/296 (52%), Positives = 218/296 (73%), Gaps = 5/296 (1%) Query: 273 QFQADRVQLAVANQTLKSEKARQ--DELIRKLADAQSQLLQSEKMASIGQLAAGVAHEIN 330 Q Q R++ A+ T + +A++ ++ I + + +SQL+Q+EK+ASIG LAAGVAHEIN Sbjct: 162 QLQMSRMEAAIQEITREVGQAKEALEKEIGERKELESQLVQTEKLASIGHLAAGVAHEIN 221 Query: 331 NPVGFVNSNLGTLQRYVDEIMALLSAYEQSEAEMPEE-IRRALAGHKARIDLDFLREDIA 389 NP+ +V+SN TL+ +V ++ +L AYE++ + +E + R L R++L F++ED+A Sbjct: 222 NPISYVSSNYTTLEEHVRRLLEVLEAYEEARPAIRDEALARRLEQLGERVELAFVKEDVA 281 Query: 390 SVFSESQDGLQRVIRIVQDLKTFSHVD-EAEKQWANLEQGLDSTLNVVSHDLKYTAEIVK 448 + ES++G+ RV +IVQDLK FS VD E + QW +L QG++STLN+V+ +LKY A++V+ Sbjct: 282 VLLRESREGIGRVRKIVQDLKNFSRVDAEDDWQWTDLHQGIESTLNIVASELKYRADVVR 341 Query: 449 EYGGIPDIECLPFQLNQVFLNLFVNAGQAI-EGRGRIVLRTGHDEDQVWVEVEDSGKGIP 507 EYG +P+++CLP Q+NQV +NL +NA QA+ RGRIV+RTGH + W+EVEDSG+GI Sbjct: 342 EYGDLPEVKCLPSQINQVVMNLVMNAAQAMGPERGRIVIRTGHTVEHAWIEVEDSGQGIS 401 Query: 508 EADLERIFEPFFTTKPVGTGTGLGLSLSYGIVAKHGGKITVRSEVGKGSVFRVSLP 563 L RIF+PFFTTKPVG GTGLGLSLSYGIV KHGG I VRS+ G GS FR+ LP Sbjct: 402 PEILPRIFDPFFTTKPVGKGTGLGLSLSYGIVQKHGGTIEVRSQPGVGSAFRIVLP 457 >VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 439 Score = 283 bits (725), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 154/320 (48%), Positives = 209/320 (65%), Gaps = 17/320 (5%) Query: 256 VPVHGAD-EIGEMARAVEQ--FQADRVQ-LAVANQTLKSEKARQDELIRKLADAQSQLLQ 311 +P+H D I + V QA + Q L +Q L+ E Q LI+KL DAQ QL+Q Sbjct: 109 IPIHSEDGTIEHVCLCVYDVTIQASQQQELKRVSQKLEEEHQSQKVLIKKLEDAQGQLIQ 168 Query: 312 SEKMASIGQLAAGVAHEINNPVGFVNSNLGTLQRYVDEIMALLSAYEQS-----EAEMPE 366 SEKMASIGQL+AG+AHEINNPVGF+ SNL TL Y + + +L + Q+ + + E Sbjct: 169 SEKMASIGQLSAGIAHEINNPVGFITSNLQTLSDYFNSLEKVLKSITQTIGQSKDTALNE 228 Query: 367 EIRRALAGHKARIDLDFLREDIASVFSESQDGLQRVIRIVQDLKTFSHVDEAEKQWANLE 426 ++ L + +DF+ ED A + +ES +G RV+ IV++LK FSHVD +E +ANLE Sbjct: 229 ACQKILKQGQ----VDFILEDTAELITESLEGSSRVMSIVKNLKEFSHVDRSEWSYANLE 284 Query: 427 QGLDSTLNVVSHDLKYTAEIVKEYG-GIPDIECLPFQLNQVFLNLFVNAGQAIEGRGRIV 485 ++STL ++++++KY + K Y +PD+ C P Q+NQV LN+ VNA AI+G G I Sbjct: 285 NCIESTLKIINNEIKYNITLEKHYAANVPDVFCQPMQINQVLLNILVNASHAIKGEGTIT 344 Query: 486 --LRTGHDEDQVWVEVEDSGKGIPEADLERIFEPFFTTKPVGTGTGLGLSLSYGIVAKHG 543 L++ D D V + + D+G GIPE ERIFEPFFTTKPVG+GTGLGLS+SYGI+ KH Sbjct: 345 ITLQSAGD-DFVEIHIRDTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIINKHN 403 Query: 544 GKITVRSEVGKGSVFRVSLP 563 G I+V SEVGKGS F + LP Sbjct: 404 GTISVTSEVGKGSEFTIRLP 423 >alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 591 Score = 231 bits (589), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 136/365 (37%), Positives = 210/365 (57%), Gaps = 51/365 (13%) Query: 250 GDALCKVPVHGADEIGEMARAVEQFQAD----------RVQLAVANQTLKSEKA--RQDE 297 G+ ++ +H DEI ++A+A +L NQ L+ E A +Q E Sbjct: 217 GNFDYRLNIHTGDEIEDLAQAFNDMAVKLSQSRETLMKNTELTNMNQRLELEIAERKQAE 276 Query: 298 L-----IRKLADAQSQLLQSEKMASIGQLAAGVAHEINNPVGFVNSNLGTLQRYVDEIMA 352 L +++L Q+QL+Q+EKM+S+GQL AGVAHEINNPV F+ N+ + Y ++++ Sbjct: 277 LELQKALQELQQTQAQLIQTEKMSSLGQLVAGVAHEINNPVSFIYGNITHAKEYTEKLLE 336 Query: 353 LLSAYEQSEAEMPEEIRRALAGHKARIDLDFLREDIASVFSESQDGLQRVIRIVQDLKTF 412 L+ Y+Q E I+ + A IDL+FL+ED+ + S + G QR+ +IV L+ F Sbjct: 337 LIHLYQQELTEPSAVIQEKI----AEIDLEFLQEDLPKILSSMKMGSQRIQQIVLSLRNF 392 Query: 413 SHVDEAEKQWANLEQGLDSTLNVVSHDLK-----YTAEIVKEYGGIPDIECLPFQLNQVF 467 S +DEAE + ++ +G++STL ++ + K Y EI+KEYG +P +EC QLNQVF Sbjct: 393 SRLDEAEMKEVDIHEGIESTLLILQNRFKAKSQSYNIEIIKEYGQLPLVECHAGQLNQVF 452 Query: 468 LNLFVNAGQAIEG-----------------------RGRIVLRTG-HDEDQVWVEVEDSG 503 +N+ NA A+EG +I +RT ++ ++V + + D+G Sbjct: 453 MNIINNAVDALEGSVVSGQWSIVNGKTTNNERLTNNSPQISIRTEINNNNRVVIRIADNG 512 Query: 504 KGIPEADLERIFEPFFTTKPVGTGTGLGLSLSYGIVA-KHGGKITVRSEVGKGSVFRVSL 562 GI + ++++F+PFFTTKPVG GTGLGLS+SY IV KH G + SE+GKG+ F + + Sbjct: 513 PGINQLVMQKLFDPFFTTKPVGQGTGLGLSISYQIVVDKHSGVLRCESEIGKGTEFWIEI 572 Query: 563 PKRGV 567 P R V Sbjct: 573 PLRQV 577 >alr4716_2 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 332 Score = 224 bits (572), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 113/276 (40%), Positives = 174/276 (63%), Gaps = 13/276 (4%) Query: 299 IRKLADAQSQLLQSEKMASIGQLAAGVAHEINNPVGFVNSNLGTLQRYVDEIMALLSAYE 358 + LA+AQ QL+Q+EKM+S+GQL AG+AHEINNPV F+ N+ + Y ++ L+ Y+ Sbjct: 56 LNDLANAQVQLIQTEKMSSLGQLVAGIAHEINNPVNFIYGNIHFIYEYTKDLWQLIILYQ 115 Query: 359 QSEAEMPEEIRRALAGHKARIDLDFLREDIASVFSESQDGLQRVIRIVQDLKTFSHVDEA 418 Q E EI A + IDLDF++ D A + + ++G +R+ IV L+ FS +DEA Sbjct: 116 QCYPEPAWEI----AAYTQEIDLDFVQNDFAKILASIKNGAERIREIVLSLRNFSRLDEA 171 Query: 419 EKQWANLEQGLDSTLNVVSHDLKYTA-----EIVKEYGGIPDIECLPFQLNQVFLNLFVN 473 E + ++ +G+D+T+ ++ + LK E+V+EY +P +EC P QLNQVF+N+ N Sbjct: 172 EIKQVDIHEGIDNTILLLKNRLKGQGKHPDIEVVREYNNLPLVECYPGQLNQVFMNILTN 231 Query: 474 AGQAI-EGRGRIVLRT---GHDEDQVWVEVEDSGKGIPEADLERIFEPFFTTKPVGTGTG 529 A +A E ++R D DQV +++ D+G G+ E +IF+PFFTTKP+G+GTG Sbjct: 232 AIEAAKESVNNPLIRIQTEALDSDQVMIQISDNGCGMTEEIRNKIFDPFFTTKPIGSGTG 291 Query: 530 LGLSLSYGIVAKHGGKITVRSEVGKGSVFRVSLPKR 565 LG+S+SY I+ KHGG + S +G+ F + +P R Sbjct: 292 LGMSISYQIIDKHGGTLKCVSAPNEGTEFIIYIPTR 327 >alr4879_2 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 287 Score = 224 bits (571), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 128/285 (44%), Positives = 180/285 (63%), Gaps = 21/285 (7%) Query: 301 KLADAQSQLLQSEKMASIGQLAAGVAHEINNPVGFVNSNLGTLQRYVDEIMALLSAYEQS 360 +L Q +L Q EKM+S+GQL AG+AHEINNPV FV NL Q YV +++ LL YE Sbjct: 5 ELRRTQLKLAQEEKMSSLGQLVAGIAHEINNPVNFVYGNLAHAQNYVGDLLNLLKLYENH 64 Query: 361 EAEMPEEIRRALAGHKARIDLDFLREDIASVFSESQDGLQRVIRIVQDLKTFSHVDEAEK 420 A EI+ I+L+F+++D+ + S Q G +RV +IV+ L+ FS +++ E Sbjct: 65 TANPSPEIQE----FSKSIELEFIKQDLPHLLSSMQMGTERVEKIVRSLRLFSRLEDLEF 120 Query: 421 QWANLEQGLDSTLNVVSHDLKY-----TAEIVKEYGGIPDIECLPFQLNQVFLNLFVNAG 475 Q NL +G+DSTL ++SH LK T I+KEYG IP +EC +LNQVF+NL NA Sbjct: 121 QLFNLHEGIDSTLIILSHRLKILPTDSTINIIKEYGDIPLVECYSGKLNQVFMNLLANAI 180 Query: 476 QAIE----GRGR-----IVLRTGHDEDQ--VWVEVEDSGKGIPEADLERIFEPFFTTKPV 524 +A+E R R I +RT +DQ V +E+ D+G GIP +RIFE FFTTKP+ Sbjct: 181 EALEESVINRERTDTLTIGIRTKVTDDQKSVLIEITDNGVGIPLEVQQRIFEQFFTTKPL 240 Query: 525 GTGTGLGLSLSYG-IVAKHGGKITVRSEVGKGSVFRVSLPKRGVL 568 G GTGLGL++++ IV KHGG + V+S GKG+ F +++P + V+ Sbjct: 241 GKGTGLGLAIAHEIIVEKHGGTLQVQSTPGKGTQFLITIPIQQVI 285