BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0031.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 410 e-114 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 395 e-110 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 364 e-100 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 363 e-100 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 325 1e-88 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 410 bits (1054), Expect = e-114, Method: Compositional matrix adjust. Identities = 213/410 (51%), Positives = 296/410 (72%), Gaps = 1/410 (0%) Query: 23 EVTYKKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAIYGLGAGIFFIGYFL 82 E TY+K++WRLIPFL+ +V+A++DRVNVGFAKLQML DL+FSE +YGLGAGIFFIGYFL Sbjct: 25 EATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYFL 84 Query: 83 FEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFMLGVFEAGFFPGVV 142 FEVPSN++L ++GAR +ARI I WGL S AM +VTTP FY++RF+LG+ EAGFFPG++ Sbjct: 85 FEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGII 144 Query: 143 LYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGTIMSQMEGVGHLANWQWLFILEGIP 202 LYLTYW+PA+RR R FMT+ A++G +GGPI+G + GV LA WQW+F++EGIP Sbjct: 145 LYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIP 204 Query: 203 SLIAGVFVLLYLPEKPANAKWLSAAEQQAVTQALVAENTSASKHLSFKDACSNYRVWLCA 262 S++ G+ VL YL + ++A+WL+ E+ +T+ + AE + + ++ RVWL + Sbjct: 205 SVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEE-AQKEDAPIAAIMASPRVWLMS 263 Query: 263 AVYFCVVSGNATIAFWTPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGIHSDKTGER 322 +YF V G ++FW P++IK+ GV L +GL++AIP+ A +AM+ +D+T ER Sbjct: 264 LIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRER 323 Query: 323 RMHSAIATLIASVGLILTGLTLGNAVMALCALTLAAIGILAAFPVFWSIPAAFLAGTAAA 382 R H AI L ++GL+L+ + N +A+ ALTL +GIL P+FWS+P AFLAGT AA Sbjct: 324 RWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAA 383 Query: 383 GGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALEFLASFLVV 432 GIALINS+GNLAGF++PY +G LK +T S SG+Y +AA L + L + Sbjct: 384 AGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGALLTL 433 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 204/433 (47%), Positives = 288/433 (66%), Gaps = 2/433 (0%) Query: 7 TSPTGNSIYTPGALDMEVT-YKKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFS 65 + + S+ P L E Y+K W L+P L+ +VL ++DRVNVGFAKLQM DLQFS Sbjct: 2 SESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFS 61 Query: 66 EAIYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYI 125 + +YGLGAG+FFIGYF E+PSNL+L ++GAR +ARI I WG+ S MA+VTTP SFY+ Sbjct: 62 DTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYV 121 Query: 126 LRFMLGVFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGTIMSQMEG 185 +RF+LGV EAGFFPG++LY++YWFP+ RR RV GLF+ S ++G +G P++G IM G Sbjct: 122 MRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNG 181 Query: 186 VGHLANWQWLFILEGIPSLIAGVFVLLYLPEKPANAKWLSAAEQQAVTQALVAENTSASK 245 A WQW+FILEGIPS++ G+ ++ L ++ +A WL+ E+ + Q + + Sbjct: 182 FQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKD-ILQTNIENEAAHYA 240 Query: 246 HLSFKDACSNYRVWLCAAVYFCVVSGNATIAFWTPSIIKEIGVKGNLQIGLISAIPFIAG 305 H +DA RVWL +YFC++SG TI FW P++I++ GVK L IG ++AIP A Sbjct: 241 HSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAA 300 Query: 306 TLAMIWNGIHSDKTGERRMHSAIATLIASVGLILTGLTLGNAVMALCALTLAAIGILAAF 365 + MI +D+ ERR H A+ ++ +VG+IL+ N V+A+ LT+ A+G L+ Sbjct: 301 AVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTI 360 Query: 366 PVFWSIPAAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALEF 425 P+FWS+P AFL G+AAA GIA INS GNL GFVAPYM+G LK T S ++G+ ++ F Sbjct: 361 PLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLF 420 Query: 426 LASFLVVVFVKKS 438 + + LV + K+ Sbjct: 421 IGAALVFLIPAKA 433 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 364 bits (935), Expect = e-100, Method: Compositional matrix adjust. Identities = 192/432 (44%), Positives = 278/432 (64%), Gaps = 2/432 (0%) Query: 1 MTSTSATSPTGNSIYTPGALDMEVTYKKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQ 60 + A + +I +P ++ +TY+K+A+R+IP L+ +++A++DRVNVGFAKLQM + Sbjct: 13 LPGVKAMKNSNTAITSPEVVE-NMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSE 71 Query: 61 DLQFSEAIYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTP 120 +L FSEAIYGLGAG+FFIGYF FE+PSN+LL K+GAR +ARI I WGL S A+V T Sbjct: 72 ELGFSEAIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTE 131 Query: 121 TSFYILRFMLGVFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGTIM 180 FYILRF+LG EAGF+PGV+LYLTYWFP+ RR + LF AG G P++G IM Sbjct: 132 WQFYILRFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIM 191 Query: 181 SQMEGVGHLANWQWLFILEGIPSLIAGVFVLLYLPEKPANAKWLSAAEQQAVTQALVAEN 240 Q WQW+F+LE IP+++ GV +LLYL AKWL+ E+ +++ + A++ Sbjct: 192 DQFHDTAGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADS 251 Query: 241 TSASKHLSFKDACSNYRVWLCAAVYFCVVSGNATIAFWTPSIIKEIGVKGNLQIGLISAI 300 + S N +W+ +YFC V G + W P++I+ GV N+ IGL+ AI Sbjct: 252 KGKAASHSLMSLVKNPMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAI 311 Query: 301 PFIAGTLAMIWNGIHSDKTGERRMHSAIATLIASVGLILTGLTLGNAVMALCALTLAAIG 360 PFI +AM+ +D ERR H + L+ +VG ++ + N +++ L++AA G Sbjct: 312 PFICAIIAMVIFSRSADHYRERRWHLVVPALLGAVGFVVAA-SATNTTVSIIFLSMAAAG 370 Query: 361 ILAAFPVFWSIPAAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFV 420 +LA P+FWS+P A L+G AAA GIALINS+ NLAGF++PYM+G ++ +T S G+Y + Sbjct: 371 VLACAPLFWSLPTAILSGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVL 430 Query: 421 AALEFLASFLVV 432 A L + +V+ Sbjct: 431 AGFLILGAAIVL 442 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 363 bits (933), Expect = e-100, Method: Compositional matrix adjust. Identities = 193/391 (49%), Positives = 260/391 (66%), Gaps = 3/391 (0%) Query: 26 YKKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAIYGLGAGIFFIGYFLFEV 85 Y + R++PFL ++ A++DR+N+GFAKLQM DL S+A YGLGAGIFF GY LFEV Sbjct: 20 YSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYMLFEV 79 Query: 86 PSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFMLGVFEAGFFPGVVLYL 145 PSNLLL KIGAR+TL+RI ILWG+ S +M +VT +FY LRF+LGVFEAGF PG++ YL Sbjct: 80 PSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGMIYYL 139 Query: 146 TYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGTIMSQMEGVGHLANWQWLFILEGIPSLI 205 T W+P +R AR + + + + G +GGP + IM G G LA WQW+F+ EGIPS++ Sbjct: 140 TQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIPSIL 199 Query: 206 AGVFVLLYLPEKPANAKWLSAAEQQAVTQALVAENTSASKHLSFKDACSNYRVWLCAAVY 265 G+ YL +KPA+A+WL+ A Q+AV +A + + SF A + ++++ AA Y Sbjct: 200 LGIAAYGYLVDKPADARWLTDA-QKAVIAGDIAR-AAPGQASSFGKALTEPKLYVLAAAY 257 Query: 266 FCVVSGNATIAFWTPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGIHSDKTGERRMH 325 FC++ G + FW PSI+K G+ QIGL SAIP +A +AM G SD+ GER +H Sbjct: 258 FCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERHLH 317 Query: 326 SAIATLIASVGLILTGLTLGNAVMALCALTLAAIGILAAFPVFWSIPAAFLAGTAAAGGI 385 SAI T + GL+ + AL ++TLA+ I A++ VFW+IP L GTAAAGGI Sbjct: 318 SAI-TAVLGAGLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAGGI 376 Query: 386 ALINSIGNLAGFVAPYMIGALKTSTGSLSSG 416 ALINSIG GF +P +IG K +TGSL +G Sbjct: 377 ALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 325 bits (834), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 179/405 (44%), Positives = 260/405 (64%), Gaps = 4/405 (0%) Query: 6 ATSPTGNSIYTPGALDMEVTYKKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFS 65 +T+ T NS P + + T+ ++ WRL+P L+ +V A +DR+N+GFAKLQM DL FS Sbjct: 2 STASTLNSTTLPLS---DSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFS 58 Query: 66 EAIYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYI 125 + +YGLGAG+FFI Y LF +PSNL+LE+IG R+ +A + ++WG S AM V T FY+ Sbjct: 59 DTVYGLGAGLFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYL 118 Query: 126 LRFMLGVFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGTIMSQMEG 185 LRF+LGV EAGFFPG+++YL WFPA+RR ++ LF + +AG +GGP++G I+ Sbjct: 119 LRFLLGVAEAGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHD 178 Query: 186 VGHLANWQWLFILEGIPSLIAGVFVLLYLPEKPANAKWLSAAEQQAVTQALVAENTSASK 245 L WQW+F++EG+P ++ GV V LPE WLS ++ + + L E + Sbjct: 179 ALGLRGWQWMFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTI 238 Query: 246 HLSFKDACSNYRVWLCAAVYFCVVSGNATIAFWTPSIIKEIGVKGNLQIGLISAIPFIAG 305 SF SN +VWL A+YF V+ TIAFW PS+I G+ + +IG++SA+P++AG Sbjct: 239 T-SFSGIFSNPQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYLAG 297 Query: 306 TLAMIWNGIHSDKTGERRMHSAIATLIASVGLILTGLTLGNAVMALCALTLAAIGILAAF 365 MI+ G SD+ ERR H I L+A+ GL L L +A + + L +A +G AA Sbjct: 298 CAFMIFIGRSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAAL 357 Query: 366 PVFWSIPAAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTST 410 P+FW +P AFL+ A GIALI+S G++A F+APY+IG ++ +T Sbjct: 358 PMFWQLPPAFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTT 402