BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0016.p (386 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2690_2 [IQR] COG1028 Dehydrogenases with different specificit... 369 e-102 SMc02322_2 [IQR] COG1028 Dehydrogenases with different specifici... 365 e-100 mlr5708_2 [IQR] COG1028 Dehydrogenases with different specificit... 328 1e-89 BH1550_2 [IQR] COG1028 Dehydrogenases with different specificiti... 271 2e-72 BS_yuxG_2 [IQR] COG1028 Dehydrogenases with different specificit... 247 3e-65 >AGl2690_2 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 271 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 173/271 (63%), Positives = 224/271 (82%) Query: 116 MPKPKSLAGRIALVTGGGGGIGQAVARQLLAEGACVMLTDIDQSSIDSAYQSLLKQAGPD 175 MPKPKSLAGR+A VTGG GGIG+A A +L EGACV+L DID++++++A +K+ D Sbjct: 1 MPKPKSLAGRVAFVTGGAGGIGRATAERLADEGACVVLADIDEAALEAAKGDFVKRYSGD 60 Query: 176 AIGVVRADITNEQDVENVISNVALRFGGIDLLVSNAGIASASPLEDTSLEVWQRNMSVLA 235 A+ V+ D+T E DV + + ++ FGG+D+LVSNAGIAS++P+EDT+L +W +N+ +LA Sbjct: 61 AVRTVKLDVTQEDDVISAFAEASVEFGGVDILVSNAGIASSAPVEDTTLAMWNKNIDILA 120 Query: 236 TGYFLVSRSAFRSMTAQAMGGSIVFVASKNGLVASAGASAYCTAKAAEIHLARCIALEGA 295 TGYFLVSR AFR + Q +GG+IVFVASKNGL +S ASAYCTAKAAEIHLARC+ALEGA Sbjct: 121 TGYFLVSREAFRLLRRQNLGGNIVFVASKNGLASSPNASAYCTAKAAEIHLARCLALEGA 180 Query: 296 PHGIRVNVVNPDAVIRGSRIWDGKWKEERAASNKIDSDNIEEFYRQRSLLKRSVLPEDIA 355 GIRVN VNPDAV+RGS+IW+G+W+E+RAAS+KI+ ++EE YR+RS+LK +V PEDIA Sbjct: 181 EAGIRVNTVNPDAVLRGSKIWNGEWREQRAASSKIEVTDLEEHYRKRSMLKLNVFPEDIA 240 Query: 356 EAVYFFASEKSAKSTGNILNVDAGNAAAFTR 386 EA+YF AS+ SAKSTGNI+NVDAGNA +FTR Sbjct: 241 EAIYFLASDASAKSTGNIINVDAGNAQSFTR 271 >SMc02322_2 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 271 Score = 365 bits (937), Expect = e-100, Method: Compositional matrix adjust. Identities = 175/271 (64%), Positives = 219/271 (80%) Query: 116 MPKPKSLAGRIALVTGGGGGIGQAVARQLLAEGACVMLTDIDQSSIDSAYQSLLKQAGPD 175 MPKPKSLAGRIALVTGG GGIG+A A +L+ EGACV+L DID++++++A L + G D Sbjct: 1 MPKPKSLAGRIALVTGGAGGIGKATANRLMQEGACVVLADIDETALEAAQTELSTRYGKD 60 Query: 176 AIGVVRADITNEQDVENVISNVALRFGGIDLLVSNAGIASASPLEDTSLEVWQRNMSVLA 235 + V ++T+E VE+ + L FGG+D+LVSNAG+A+++ +EDT+L +W +NM +LA Sbjct: 61 FVRSVNMNVTSEAAVESGFGDALLAFGGLDILVSNAGLATSAAVEDTTLALWNKNMDILA 120 Query: 236 TGYFLVSRSAFRSMTAQAMGGSIVFVASKNGLVASAGASAYCTAKAAEIHLARCIALEGA 295 TGYFLVSR AFR Q GG++VFVASKNGL AS GASAYCTAKAAEIHLARC+ALEGA Sbjct: 121 TGYFLVSREAFRIFRNQKAGGNVVFVASKNGLAASPGASAYCTAKAAEIHLARCLALEGA 180 Query: 296 PHGIRVNVVNPDAVIRGSRIWDGKWKEERAASNKIDSDNIEEFYRQRSLLKRSVLPEDIA 355 IRVNVVNPDAV+RGS+IW G+WKE+RAA+ K+D D +E YR+RS+LK SV PEDIA Sbjct: 181 SAQIRVNVVNPDAVLRGSKIWTGEWKEQRAAAYKMDVDELEAHYRERSMLKLSVFPEDIA 240 Query: 356 EAVYFFASEKSAKSTGNILNVDAGNAAAFTR 386 EA+YF AS+ SAKSTGNI+NVDAGNA +FTR Sbjct: 241 EAIYFLASDMSAKSTGNIVNVDAGNAQSFTR 271 >mlr5708_2 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 262 Score = 328 bits (841), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 167/262 (63%), Positives = 214/262 (81%) Query: 125 RIALVTGGGGGIGQAVARQLLAEGACVMLTDIDQSSIDSAYQSLLKQAGPDAIGVVRADI 184 +IALVTGG GGIG+A A +LL EGACV+L DID++++ +A + L K G D + V ++ Sbjct: 1 QIALVTGGAGGIGRATANRLLREGACVVLADIDEAALATANEELAKTYGKDFVRPVVINV 60 Query: 185 TNEQDVENVISNVALRFGGIDLLVSNAGIASASPLEDTSLEVWQRNMSVLATGYFLVSRS 244 T+E V + + A+ FGGID+LVSNAG+AS++P+E+T+L +W +NM +L+TGYFLVSR Sbjct: 61 TSEDQVISGFAETAVEFGGIDILVSNAGLASSAPIEETTLALWNKNMDILSTGYFLVSRE 120 Query: 245 AFRSMTAQAMGGSIVFVASKNGLVASAGASAYCTAKAAEIHLARCIALEGAPHGIRVNVV 304 AFR Q +GG++VFVASKNGL AS A+AYCTAKAAEIHLARC+ALEGA IRVNVV Sbjct: 121 AFRLFRVQKIGGNVVFVASKNGLAASPNAAAYCTAKAAEIHLARCLALEGAEAQIRVNVV 180 Query: 305 NPDAVIRGSRIWDGKWKEERAASNKIDSDNIEEFYRQRSLLKRSVLPEDIAEAVYFFASE 364 NPDAV+RGS+IW G+WKE+RAA+ K+ +D++EE YR RS+LKRSV PEDIAEA+YFFAS+ Sbjct: 181 NPDAVLRGSKIWTGEWKEQRAAAYKMSTDDLEEHYRSRSMLKRSVFPEDIAEAIYFFASD 240 Query: 365 KSAKSTGNILNVDAGNAAAFTR 386 SAKSTGNI+NVDAGNA +FTR Sbjct: 241 MSAKSTGNIINVDAGNAQSFTR 262 >BH1550_2 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bha Bacillus halodurans Length = 264 Score = 271 bits (693), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 129/262 (49%), Positives = 180/262 (68%) Query: 125 RIALVTGGGGGIGQAVARQLLAEGACVMLTDIDQSSIDSAYQSLLKQAGPDAIGVVRADI 184 ++A VTGG GGIG RQ +AEGA V++ D++ + + +Q G D V+ D+ Sbjct: 3 KVAFVTGGAGGIGSETCRQFVAEGAHVVVADLNLEGAEKVVSEINEQYGTDRALAVKMDV 62 Query: 185 TNEQDVENVISNVALRFGGIDLLVSNAGIASASPLEDTSLEVWQRNMSVLATGYFLVSRS 244 T+E+ V+ +L +GGID++V+NAG+A++SP ++T+L+ W NM+VL TGYFLV+R Sbjct: 63 TSEEQVQAAFKQASLTYGGIDIVVNNAGLATSSPFDETTLDEWNLNMNVLGTGYFLVARE 122 Query: 245 AFRSMTAQAMGGSIVFVASKNGLVASAGASAYCTAKAAEIHLARCIALEGAPHGIRVNVV 304 AF+ M Q GG++VF+ SKN + A A+AY +AKA E HLARCIA EG P GIRVN V Sbjct: 123 AFKQMKVQGTGGNMVFIGSKNSVYAGKNATAYSSAKALETHLARCIAAEGGPFGIRVNSV 182 Query: 305 NPDAVIRGSRIWDGKWKEERAASNKIDSDNIEEFYRQRSLLKRSVLPEDIAEAVYFFASE 364 PDAV++GS IW +W++ERA + I+ D +EE YR+R+ L +V P DIA A+ FFAS Sbjct: 183 LPDAVLQGSAIWGSRWRQERATAYGIEPDQLEEHYRKRTTLLVNVYPGDIAAAILFFASS 242 Query: 365 KSAKSTGNILNVDAGNAAAFTR 386 K+ K+TG +L VD G AAFTR Sbjct: 243 KAEKTTGCMLTVDGGVPAAFTR 264 >BS_yuxG_2 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 264 Score = 247 bits (631), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 132/262 (50%), Positives = 177/262 (67%) Query: 125 RIALVTGGGGGIGQAVARQLLAEGACVMLTDIDQSSIDSAYQSLLKQAGPDAIGVVRADI 184 ++AL+TGG GGIG A R+ AEG V++ D++ + G V+ D+ Sbjct: 3 KVALITGGAGGIGSAACRRFAAEGGHVIVADLNIEGAQKIAGEINDAYGKGRAMAVKMDV 62 Query: 185 TNEQDVENVISNVALRFGGIDLLVSNAGIASASPLEDTSLEVWQRNMSVLATGYFLVSRS 244 T E+DV++ AL +GGID++V+NAG+A++SP ++TSL+ W NM+VL TGYFLV+R Sbjct: 63 TKEEDVQSAFERAALAYGGIDIVVNNAGLATSSPFDETSLKEWNLNMNVLGTGYFLVARE 122 Query: 245 AFRSMTAQAMGGSIVFVASKNGLVASAGASAYCTAKAAEIHLARCIALEGAPHGIRVNVV 304 AF+ M Q GGS+VFV SKN + A ASAY + KA E HLARCIA EG GIRVN V Sbjct: 123 AFKQMKHQNRGGSMVFVGSKNSVYAGKNASAYSSVKALETHLARCIAAEGGEFGIRVNSV 182 Query: 305 NPDAVIRGSRIWDGKWKEERAASNKIDSDNIEEFYRQRSLLKRSVLPEDIAEAVYFFASE 364 PDAV++GS IW W+EERAA+ I+ D +EE YR+R+ L ++ PEDIAEA+ FFAS Sbjct: 183 LPDAVLQGSAIWGSSWREERAAAYGIEPDQLEEHYRKRTALLVNIYPEDIAEAIAFFASS 242 Query: 365 KSAKSTGNILNVDAGNAAAFTR 386 K+ K+TG ++ VD G AAFTR Sbjct: 243 KAEKTTGCMITVDGGVPAAFTR 264