BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0178.p (621 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex... 915 0.0 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 620 e-177 NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex... 607 e-173 PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex ... 575 e-164 XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex ... 535 e-151 >RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex Rso Ralstonia solanacearum Length = 654 Score = 915 bits (2364), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/646 (70%), Positives = 525/646 (81%), Gaps = 30/646 (4%) Query: 5 PSPSPVDPREIVLET---VAKLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLS 61 P+P+ VDP E + +A+LP LPGVYRYFDA+ +VLYVGKARDLKKRVSSYF KTL Sbjct: 10 PAPA-VDPSEAAFDAKAHIARLPSLPGVYRYFDAQGSVLYVGKARDLKKRVSSYFTKTLL 68 Query: 62 SPRIAMMVERIARLETTVTRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAY 121 SPRIAMMV +IA +ETTV RSEAEALLLENNLIK L PR+NILFRDDKSYPYLK+T HAY Sbjct: 69 SPRIAMMVAKIAHIETTVVRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTQHAY 128 Query: 122 PRMAYYRGAVDKKNQYFGPFPNAWAVKESIQILQKVFLLRTCEDTVYANRTRPCLLHQIH 181 PRMAYYRGA D+K+QYFGPFP+A AV+ES+QILQKVF LRTCEDTV+ NRTRPCLLHQIH Sbjct: 129 PRMAYYRGATDRKHQYFGPFPSAHAVRESMQILQKVFQLRTCEDTVFNNRTRPCLLHQIH 188 Query: 182 RCSGPCVKLISTEDYALDVENASKFLRGRQSEVLDALEKKMHAYAGELKFEQAAAVRNQI 241 RC+ PCV+ IS EDYA DV NA+ FL GRQ EV+ L+ KM +A L+FEQAA VR+QI Sbjct: 189 RCTAPCVQAISAEDYARDVANAAGFLLGRQDEVMQTLQDKMQRHAAALEFEQAATVRDQI 248 Query: 242 TSLSSVLHQQTMETGGDA-DIDIIAVIVQGGRACVNLAMVRGGRHLGDRAYFPTHV-DGA 299 +LS+VL +Q++E G A DIDI+AV ++GG ACVNLAMVRGGRHLGD+AYFPTHV +GA Sbjct: 249 GALSTVLTRQSVEEVGQASDIDILAVAIKGGHACVNLAMVRGGRHLGDKAYFPTHVEEGA 308 Query: 300 ----------IPDGEES----------IEAEVLKAFIAQHYIEKFIPGNLIVNTEFDDPA 339 +P+G E+ + ++L+AF+AQHY+++F+P L+V+ Sbjct: 309 AIVGVDVEADVPEGAETQPEPARDPERMARDILEAFVAQHYLDQFVPPVLVVSHPIRAAG 368 Query: 340 LMLALMEQCGHRITLTLQPQGQRRQWLEMAHKGGEIALARLLSEQGSQQARTRALVEALG 399 L+ AL Q G R+++ QPQG RR WLEMA KG E++LAR LSEQGSQQARTRAL E +G Sbjct: 369 LIEALAAQAGRRVSVVRQPQGARRAWLEMAEKGAELSLARRLSEQGSQQARTRALAETIG 428 Query: 400 TEVEDIEALRVECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNINDITPGDDYAAMRQ 459 ++ED+ ALRVECFDISHT GEATQASCVVFH HAMQNGEYRRYNI DI PGDDYAAMRQ Sbjct: 429 VDLEDLAALRVECFDISHTAGEATQASCVVFHSHAMQNGEYRRYNIQDIIPGDDYAAMRQ 488 Query: 460 VLTRRYEKV----ANGDGAMPDIVLIDGGKGQVEIARQVFTELGLDISLIVGVAKGEGRK 515 VLTRRY+KV A MP +VLIDGGKGQVE+ARQVF ELGLDI L+VGVAKGEGRK Sbjct: 489 VLTRRYQKVVEQAAEDAPDMPRVVLIDGGKGQVEVARQVFEELGLDIGLLVGVAKGEGRK 548 Query: 516 VGLETLVFVDGRAPQELGKESAALMLIAQIRDEAHRFAITGMRAKRAKARQTSRLEEIEG 575 VGLETLVF DGR ELG+ SAALML+AQIRDEAHRFAITGMRAKRAKAR TSRLEEIEG Sbjct: 549 VGLETLVFADGRPSLELGQGSAALMLVAQIRDEAHRFAITGMRAKRAKARNTSRLEEIEG 608 Query: 576 IGAKRRQKLLARFGGLRGVADASIDELASVEGISHTLAEEIYRQLH 621 IGAKRRQ+LLARFGGLRGV AS++ELA+VEGIS TLAEEIYRQLH Sbjct: 609 IGAKRRQRLLARFGGLRGVMAASVEELATVEGISQTLAEEIYRQLH 654 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 620 bits (1600), Expect = e-177, Method: Compositional matrix adjust. Identities = 322/610 (52%), Positives = 415/610 (68%), Gaps = 17/610 (2%) Query: 20 VAKLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLSSPRIAMMVERIARLETTV 79 + LP LPGVYR+FD VLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 28 LKNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 87 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAYPRMAYYRGAVDKKNQYFG 139 TRSEAEAL+LENN IK L P++NILFRDDKSYPYL ++GH YP+MAYYRG + K NQYFG Sbjct: 88 TRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 147 Query: 140 PFPNAWAVKESIQILQKVFLLRTCEDTVYANRTRPCLLHQIHRCSGPCVKLISTEDYALD 199 P+PN+ AV++SIQILQKVF+LRTCED+V+ +R RPCLL+QI RC+ PCV IS EDY Sbjct: 148 PYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 207 Query: 200 VENASKFLRGRQSEVLDALEKKMHAYAGELKFEQAAAVRNQITSLSSVLHQQTMET---G 256 V A+ FL G+ E+ L+ KM A L+FE+AA R+QI +L + Q +++ Sbjct: 208 VRQAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 267 Query: 257 GDADIDIIAVIVQGGRACVNLAMVRGGRHLGDRAYFPTHVDGAIPDGEESIEAEVLKAFI 316 DID++A+ V G CV+ +RGGRH+GD+++FP + P+G++ E AF+ Sbjct: 268 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 322 Query: 317 AQHYIEKFIPGNLIVNTEFDDPALMLALMEQCGHRITLTLQPQGQRRQWLEMAHKGGEIA 376 AQHY+ K P +I N D AL AL + G ++ + G+R+ WL+MA + ++A Sbjct: 323 AQHYLGKSKPDIIINNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMA 381 Query: 377 LARLLSEQGSQQARTRALVEALGTEVEDIEALRVECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q +QQ R L + LG + + + R+ECFDISHTQGEAT ASCVV+ +Q Sbjct: 382 IAQRRLQQSNQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 439 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGDGA-MPDIVLIDGGKGQVEIA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANG+ PD VLIDGGKGQ+ IA Sbjct: 440 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGIA 499 Query: 492 RQVFTELGLDISLIVGVAKGEGRKVGLETLVFVDGRAPQELGKESAALMLIAQIRDEAHR 551 V+ ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 500 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 558 Query: 552 FAITGMRAKRAKARQTSRLEEIEGIGAKRRQKLLARFGGLRGVADASIDELASVEGISHT 611 FAITG R KR KAR TS L +I G+G+KRRQ LL RFGGLRGV AS ++L VEGIS Sbjct: 559 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 618 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 619 LAETIYEHLH 628 >NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex Nme Neisseria meningitidis MC58 Length = 617 Score = 607 bits (1565), Expect = e-173, Method: Compositional matrix adjust. Identities = 319/610 (52%), Positives = 416/610 (68%), Gaps = 17/610 (2%) Query: 20 VAKLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLSSPRIAMMVERIARLETTV 79 + LP+LPGVYR+F+ NVLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 17 LKNLPNLPGVYRFFNESGNVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 76 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAYPRMAYYRGAVDKKNQYFG 139 TRSE+EAL+LENN IK L P++NILFRDDKSYPYL ++GH YP+MAYYRG + K NQYFG Sbjct: 77 TRSESEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 136 Query: 140 PFPNAWAVKESIQILQKVFLLRTCEDTVYANRTRPCLLHQIHRCSGPCVKLISTEDYALD 199 P+PN+ AV++SIQ+LQKVF+LRTCED+V+ +R RPCLL+QI RC+ PCV IS EDY Sbjct: 137 PYPNSNAVRDSIQVLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 196 Query: 200 VENASKFLRGRQSEVLDALEKKMHAYAGELKFEQAAAVRNQITSLSSVLHQQTMET---G 256 V A+ FL G+ E+ L+ KM A L+FE+AA R+QI +L + Q +++ Sbjct: 197 VREAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 256 Query: 257 GDADIDIIAVIVQGGRACVNLAMVRGGRHLGDRAYFPTHVDGAIPDGEESIEAEVLKAFI 316 DID++A+ V G CV+ +RGGRH+GD+++FP + P+G++ E AF+ Sbjct: 257 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 311 Query: 317 AQHYIEKFIPGNLIVNTEFDDPALMLALMEQCGHRITLTLQPQGQRRQWLEMAHKGGEIA 376 AQHY+ K P +I N D AL AL + G ++ + G+R+ L+MA + ++A Sbjct: 312 AQHYLGKSKPDIIISNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVRLKMAEQNAQMA 370 Query: 377 LARLLSEQGSQQARTRALVEALGTEVEDIEALRVECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q SQQ R L + LG + + + R+ECFDISHTQGEAT ASCVV+ +Q Sbjct: 371 IAQRRLQQSSQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 428 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGDGA-MPDIVLIDGGKGQVEIA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANG+ PD VLIDGGKGQ+ +A Sbjct: 429 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVA 488 Query: 492 RQVFTELGLDISLIVGVAKGEGRKVGLETLVFVDGRAPQELGKESAALMLIAQIRDEAHR 551 V+ ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 489 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 547 Query: 552 FAITGMRAKRAKARQTSRLEEIEGIGAKRRQKLLARFGGLRGVADASIDELASVEGISHT 611 FAITG R KR KAR TS L +I G+G+KRRQ LL RFGGLRGV AS ++L VEGIS Sbjct: 548 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 607 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 608 LAETIYNHLH 617 >PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex Pae Pseudomonas aeruginosa Length = 608 Score = 575 bits (1483), Expect = e-164, Method: Compositional matrix adjust. Identities = 309/607 (50%), Positives = 411/607 (67%), Gaps = 16/607 (2%) Query: 20 VAKLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLSSPRIAMMVERIARLETTV 79 +A + PGVYR FDAE +LYVGKA+ LKKR++SYF+K+ +P+ A +V RIA++ETT+ Sbjct: 11 LATCSNRPGVYRMFDAEAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTI 70 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGH-AYPRMAYYRGAVDKKNQYF 138 T +E EALLLE LIK RP +NIL RDDKSYP++ ++ YPR++ +RGA +K +YF Sbjct: 71 TANETEALLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYF 130 Query: 139 GPFPNAWAVKESIQILQKVFLLRTCEDTVYANRTRPCLLHQIHRCSGPCVKLISTEDYAL 198 GP+P+A A++ES+ +LQK FL+R CED+ + NRTRPCL +QI RC GPCV L+S E+YA Sbjct: 131 GPYPSAGAIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAE 190 Query: 199 DVENASKFLRGRQSEVLDALEKKMHAYAGELKFEQAAAVRNQITSLSSVLHQQTMETGGD 258 DV ++ FL GR + + D L M A L FE+AA +R+Q+ L V QQ+ME GG+ Sbjct: 191 DVRHSVMFLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSME-GGN 249 Query: 259 ADIDIIAVIVQGGRACVNLAMVRGGRHLGDRAYFPTHVDGAIPDGEESIEAEVLKAFIAQ 318 D+DI+A IV G ACV+L VRGGR LG + +FP AI EE + EVL AF+ Q Sbjct: 250 GDVDIVAAIVTPGGACVHLISVRGGRVLGSKNFFP---QVAI---EEEV-GEVLLAFLGQ 302 Query: 319 HYI---EKFIPGNLIVNTEFDD-PALMLALMEQCGHRITLTLQPQGQRRQWLEMAHKGGE 374 +Y+ E+ +P LIVN +D P L+ A+ E G + ++ + +G R +W ++A E Sbjct: 303 YYLSHQERDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAE 362 Query: 375 IALARLLSEQGSQQARTRALVEALGTEVEDIEALRVECFDISHTQGEATQASCVVFHHHA 434 AL L+ + AR AL EAL E + R+ECFDISH+ GEAT ASCVVF Sbjct: 363 QALGARLANRQHVAARFEALAEALDL-AEPPQ--RLECFDISHSSGEATVASCVVFGPEG 419 Query: 435 MQNGEYRRYNINDITPGDDYAAMRQVLTRRYEKVANGDGAMPDIVLIDGGKGQVEIARQV 494 +YRRYNI +T GDDYAAM Q LTRR+ ++ +G+G MPDI+L+DGGKGQ+ +A++V Sbjct: 420 PLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEV 479 Query: 495 FTELGLDISLIVGVAKGEGRKVGLETLVFVDGRAPQELGKESAALMLIAQIRDEAHRFAI 554 EL + +++GVAKG RK GLETL D L +S AL LI QIRDEAHRFAI Sbjct: 480 LQELAVAGLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAI 539 Query: 555 TGMRAKRAKARQTSRLEEIEGIGAKRRQKLLARFGGLRGVADASIDELASVEGISHTLAE 614 TG RA+R KAR+TS LE++ G+G KRR+ LL FGGL+ ++ ASIDELA GIS LAE Sbjct: 540 TGHRARRGKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAE 599 Query: 615 EIYRQLH 621 +IY LH Sbjct: 600 QIYAVLH 606 >XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex Xfa Xylella fastidiosa 9a5c Length = 627 Score = 535 bits (1377), Expect = e-151, Method: Compositional matrix adjust. Identities = 284/606 (46%), Positives = 396/606 (65%), Gaps = 19/606 (3%) Query: 21 AKLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLSSPRIAMMVERIARLETTVT 80 A L PGVY + A+D +LYVGKA L+KRV+SYF T + R+ M+ ++ R++ T+T Sbjct: 22 AHLSMAPGVYCMYAADDTLLYVGKAGALRKRVASYFNGTPKNTRLTAMLAQVVRMDVTIT 81 Query: 81 RSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAYPRMAYYRGAVDKKNQYFGP 140 R+EAEALLLEN LIK+L PR+N+L RDDKSYPY+ +T A+PR+A +RG +YFGP Sbjct: 82 RNEAEALLLENQLIKSLAPRYNVLLRDDKSYPYVLLTREAWPRIALHRGPQIVPGRYFGP 141 Query: 141 FPNAWAVKESIQILQKVFLLRTCEDTVYANRTRPCLLHQIHRCSGPCVKLISTEDYALDV 200 +P AV++ + ++ K+F LR+CED+V+ NR+RPCL +QI RCS PCV +++ ++Y V Sbjct: 142 YPGVTAVRDMLNLIHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVNVVTHDNYTEAV 201 Query: 201 ENASKFLRGRQSEVLDALEKKMHAYAGELKFEQAAAVRNQITSLSSVLHQQTMETGGDAD 260 + FL G+ + + L + M + L+FEQAA +R+ +TSL S+ ++Q ++ G AD Sbjct: 202 RRVTLFLEGKSDLLAEELIQAMQVASEHLEFEQAARLRDLLTSLRSMQNRQYVD-GRAAD 260 Query: 261 IDIIAVIVQGGRACVNLAMVRGGRHLGDRAYFPTHVDGAIPDGEESIEAEVLKAFIAQHY 320 +D++A G ACV L R GR+LG R +FP +GEE AE+L AF++Q+Y Sbjct: 261 LDVLACAALSGHACVLLLSFRDGRNLGTRMFFPK------TNGEERT-AEILSAFVSQYY 313 Query: 321 IEKFIPGNLIVNTEFDDPALM-LALMEQCGHRITLTLQPQGQRRQWLEMAHKGGEIALAR 379 E P ++++ E D L+ A H+I+L +G+R ++E+A + ++AL+ Sbjct: 314 AEYPPPPEILLDQEIPDHTLLEAAFSRSSAHKISLRWNVRGERAGYVELAVRNAQVALST 373 Query: 380 LLSEQGSQQARTRALVEALGTEVEDIEALRVECFDISHTQGEATQASCVVFHHHAMQNGE 439 L+ Q +Q+ R+ A+ + LG E E I+ RVECFDISHT GEAT ASCVVF + Sbjct: 374 ELTSQRAQRVRSEAVRQLLGLE-EPIK--RVECFDISHTMGEATVASCVVFDAVGPVRSQ 430 Query: 440 YRRYNINDITPGDDYAAMRQVLTRRYEKVANGD--GAMPDIVLIDGGKGQVEIARQVFTE 497 YRRYNI ITPGDDYAAMRQ + RR+ + D G PD++ IDGG GQ+ A+ Sbjct: 431 YRRYNITGITPGDDYAAMRQAIERRFRRAVEEDKQGERPDVLFIDGGAGQLAQAKMALNA 490 Query: 498 LGLDISLIVGVAKGEGRKVGLETLVFVDGRAPQEL--GKESAALMLIAQIRDEAHRFAIT 555 +G++ L+VGV+KGE R+ G ETL+ +DG QEL G S AL I Q+RDEAHRFAIT Sbjct: 491 VGVESVLLVGVSKGEERRAGHETLIMLDG---QELHPGAASPALQFIQQVRDEAHRFAIT 547 Query: 556 GMRAKRAKARQTSRLEEIEGIGAKRRQKLLARFGGLRGVADASIDELASVEGISHTLAEE 615 G RA+R K R TS+LE+I GIG++RR LL FGGL GV A E+A VEGIS LA + Sbjct: 548 GHRARRQKTRMTSKLEDIPGIGSRRRANLLKHFGGLAGVKAAGQTEIARVEGISTALAAK 607 Query: 616 IYRQLH 621 IY LH Sbjct: 608 IYASLH 613