BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0085.p (393 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1502 [R] COG3960 Glyoxylate carboligase Pae Pseudomonas aerugi... 662 0.0 STM0517 [R] COG3960 Glyoxylate carboligase Sty Salmonella typhim... 628 e-180 gcl [R] COG3960 Glyoxylate carboligase Eco Escherichia coli K12 625 e-179 Zgcl [R] COG3960 Glyoxylate carboligase EcZ Escherichia coli O15... 625 e-179 ECs0568 [R] COG3960 Glyoxylate carboligase Ecs Escherichia coli ... 625 e-179 >PA1502 [R] COG3960 Glyoxylate carboligase Pae Pseudomonas aeruginosa Length = 591 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/393 (79%), Positives = 345/393 (87%) Query: 1 MLNQSERPLLTIGGGVVNADAAELAVEFAELTGVPVIPTLMAWGAIPDDHPQMAGMVGLQ 60 ML+++ERPLL GGG+ NADAAE EFAELTG+PVIPTLM WG IPDDHPQMAGMVGLQ Sbjct: 199 MLDEAERPLLVAGGGIFNADAAERFREFAELTGIPVIPTLMGWGVIPDDHPQMAGMVGLQ 258 Query: 61 TSHRYGNATMLASDFVLGIGNRWANRHTGSIEVFTKDRTFVHVDIEPTQIGRVFGPDYGI 120 TSHRYGNAT+L SD VLGIGNRWANRHTGS+EV+T+ R F+HVDIEPTQIGRVF PD GI Sbjct: 259 TSHRYGNATLLESDLVLGIGNRWANRHTGSVEVYTEGRRFIHVDIEPTQIGRVFMPDLGI 318 Query: 121 VSDAKAALKLFIEVAKELKAAGNLPDRSAWLADCQERKRTLHRRTHFEEVPIKPQRVYEE 180 VSDA AAL F+EVA+E KAAG L R+AWL CQ+RKRTL R+THF+ VP+KPQRVYEE Sbjct: 319 VSDAGAALDAFLEVAREWKAAGKLKSRAAWLESCQQRKRTLQRKTHFDNVPVKPQRVYEE 378 Query: 181 MNRAFGRDTCYVSTIGLSQIAAAQFLHVYKDRHWINCGQAGPLGWTISAALGVCAADPQR 240 MN FG+D CYVSTIGLSQIA AQFLHVY+ RHWINCGQAGPLGWTI AALGV ADP R Sbjct: 379 MNEFFGKDACYVSTIGLSQIAGAQFLHVYQPRHWINCGQAGPLGWTIPAALGVVKADPSR 438 Query: 241 KVVAISGDYDFQFMIEELAVGAQFNLPYLHVVVNNSYLGLIRQAQRGFEMDYCVQLAFEN 300 +VVA+SGDYDFQFMIEELAVGAQF LPY+HV+VNNSYLGLIRQAQRGF+MDYCVQLAF+N Sbjct: 439 QVVALSGDYDFQFMIEELAVGAQFKLPYIHVLVNNSYLGLIRQAQRGFDMDYCVQLAFDN 498 Query: 301 INAPELNGYGVDHVAVVEGLGCKAIRVTNPNEIQDAFAVAQRWMAEYRVPVVVEIILERV 360 INAPEL GYGVDHVAVVEGLGCKAIRV +PNEI A A A+ M +++VPVVVE+ILER+ Sbjct: 499 INAPELEGYGVDHVAVVEGLGCKAIRVFDPNEIGAALAKARELMQQHQVPVVVEVILERI 558 Query: 361 TNIAMGTEINAINEFEELATKRGHAPTAISLLD 393 TNI+MGTEINAINEFEELA K APTAISLLD Sbjct: 559 TNISMGTEINAINEFEELAEKGADAPTAISLLD 591 >STM0517 [R] COG3960 Glyoxylate carboligase Sty Salmonella typhimurium LT2 Length = 593 Score = 628 bits (1620), Expect = e-180, Method: Compositional matrix adjust. Identities = 289/392 (73%), Positives = 335/392 (85%) Query: 1 MLNQSERPLLTIGGGVVNADAAELAVEFAELTGVPVIPTLMAWGAIPDDHPQMAGMVGLQ 60 ML QSERP++ GGGV+NADAA L +FAELT VPVIPTLM WG IPDDHP MAGMVGLQ Sbjct: 199 MLIQSERPVIVAGGGVINADAAPLLQQFAELTNVPVIPTLMGWGCIPDDHPLMAGMVGLQ 258 Query: 61 TSHRYGNATMLASDFVLGIGNRWANRHTGSIEVFTKDRTFVHVDIEPTQIGRVFGPDYGI 120 T+HRYGNAT+LASD V GIGNR+ANRHTGS+E +T+ R +H+DIEPTQIGRV PD GI Sbjct: 259 TAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTQGRKIIHIDIEPTQIGRVLCPDLGI 318 Query: 121 VSDAKAALKLFIEVAKELKAAGNLPDRSAWLADCQERKRTLHRRTHFEEVPIKPQRVYEE 180 VSDAKAAL L I+VA+E++ AG LP R W+ +CQ+RKRTL R+THF+ VP+KPQRVYEE Sbjct: 319 VSDAKAALTLLIDVAQEMQKAGRLPCRKTWVDECQQRKRTLLRKTHFDNVPVKPQRVYEE 378 Query: 181 MNRAFGRDTCYVSTIGLSQIAAAQFLHVYKDRHWINCGQAGPLGWTISAALGVCAADPQR 240 MN+AFGRD CYV+TIGLSQIAAAQ LHV+KDRHWINCGQAGPLGWTI AALGVCAADPQR Sbjct: 379 MNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPQR 438 Query: 241 KVVAISGDYDFQFMIEELAVGAQFNLPYLHVVVNNSYLGLIRQAQRGFEMDYCVQLAFEN 300 VVAISGD+DFQF+IEELAVGAQFN+PY+HV+VNN+YLGLIRQ+QR F+MDYCVQLAFEN Sbjct: 439 NVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFEN 498 Query: 301 INAPELNGYGVDHVAVVEGLGCKAIRVTNPNEIQDAFAVAQRWMAEYRVPVVVEIILERV 360 IN+ E+NGYGVDHV V EGLGCKAIRV P +I AF A+ MA+YRVPVVVE+ILERV Sbjct: 499 INSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERV 558 Query: 361 TNIAMGTEINAINEFEELATKRGHAPTAISLL 392 TNI+MG+E++ + EFEE+A APT + Sbjct: 559 TNISMGSELDNVTEFEEVADSAKDAPTETCFM 590 >gcl [R] COG3960 Glyoxylate carboligase Eco Escherichia coli K12 Length = 593 Score = 625 bits (1611), Expect = e-179, Method: Compositional matrix adjust. Identities = 288/392 (73%), Positives = 335/392 (85%) Query: 1 MLNQSERPLLTIGGGVVNADAAELAVEFAELTGVPVIPTLMAWGAIPDDHPQMAGMVGLQ 60 ML Q+ERP++ GGGV+NADAA L +FAELT VPVIPTLM WG IPDDH MAGMVGLQ Sbjct: 199 MLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQ 258 Query: 61 TSHRYGNATMLASDFVLGIGNRWANRHTGSIEVFTKDRTFVHVDIEPTQIGRVFGPDYGI 120 T+HRYGNAT+LASD V GIGNR+ANRHTGS+E +T+ R VH+DIEPTQIGRV PD GI Sbjct: 259 TAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGI 318 Query: 121 VSDAKAALKLFIEVAKELKAAGNLPDRSAWLADCQERKRTLHRRTHFEEVPIKPQRVYEE 180 VSDAKAAL L +EVA+E++ AG LP R W+ADCQ+RKRTL R+THF+ VP+KPQRVYEE Sbjct: 319 VSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEE 378 Query: 181 MNRAFGRDTCYVSTIGLSQIAAAQFLHVYKDRHWINCGQAGPLGWTISAALGVCAADPQR 240 MN+AFGRD CYV+TIGLSQIAAAQ LHV+KDRHWINCGQAGPLGWTI AALGVCAADP+R Sbjct: 379 MNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKR 438 Query: 241 KVVAISGDYDFQFMIEELAVGAQFNLPYLHVVVNNSYLGLIRQAQRGFEMDYCVQLAFEN 300 VVAISGD+DFQF+IEELAVGAQFN+PY+HV+VNN+YLGLIRQ+QR F+MDYCVQLAFEN Sbjct: 439 NVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFEN 498 Query: 301 INAPELNGYGVDHVAVVEGLGCKAIRVTNPNEIQDAFAVAQRWMAEYRVPVVVEIILERV 360 IN+ E+NGYGVDHV V EGLGCKAIRV P +I AF A+ MA+YRVPVVVE+ILERV Sbjct: 499 INSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERV 558 Query: 361 TNIAMGTEINAINEFEELATKRGHAPTAISLL 392 TNI+MG+E++ + EFE++A APT + Sbjct: 559 TNISMGSELDNVMEFEDIADNAADAPTETCFM 590 >Zgcl [R] COG3960 Glyoxylate carboligase EcZ Escherichia coli O157:H7 EDL933 Length = 593 Score = 625 bits (1611), Expect = e-179, Method: Compositional matrix adjust. Identities = 288/392 (73%), Positives = 335/392 (85%) Query: 1 MLNQSERPLLTIGGGVVNADAAELAVEFAELTGVPVIPTLMAWGAIPDDHPQMAGMVGLQ 60 ML Q+ERP++ GGGV+NADAA L +FAELT VPVIPTLM WG IPDDH MAGMVGLQ Sbjct: 199 MLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQ 258 Query: 61 TSHRYGNATMLASDFVLGIGNRWANRHTGSIEVFTKDRTFVHVDIEPTQIGRVFGPDYGI 120 T+HRYGNAT+LASD V GIGNR+ANRHTGS+E +T+ R VH+DIEPTQIGRV PD GI Sbjct: 259 TAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGI 318 Query: 121 VSDAKAALKLFIEVAKELKAAGNLPDRSAWLADCQERKRTLHRRTHFEEVPIKPQRVYEE 180 VSDAKAAL L +EVA+E++ AG LP R W+ADCQ+RKRTL R+THF+ VP+KPQRVYEE Sbjct: 319 VSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEE 378 Query: 181 MNRAFGRDTCYVSTIGLSQIAAAQFLHVYKDRHWINCGQAGPLGWTISAALGVCAADPQR 240 MN+AFGRD CYV+TIGLSQIAAAQ LHV+KDRHWINCGQAGPLGWTI AALGVCAADP+R Sbjct: 379 MNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKR 438 Query: 241 KVVAISGDYDFQFMIEELAVGAQFNLPYLHVVVNNSYLGLIRQAQRGFEMDYCVQLAFEN 300 VVAISGD+DFQF+IEELAVGAQFN+PY+HV+VNN+YLGLIRQ+QR F+MDYCVQLAFEN Sbjct: 439 NVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFEN 498 Query: 301 INAPELNGYGVDHVAVVEGLGCKAIRVTNPNEIQDAFAVAQRWMAEYRVPVVVEIILERV 360 IN+ E+NGYGVDHV V EGLGCKAIRV P +I AF A+ MA+YRVPVVVE+ILERV Sbjct: 499 INSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERV 558 Query: 361 TNIAMGTEINAINEFEELATKRGHAPTAISLL 392 TNI+MG+E++ + EFE++A APT + Sbjct: 559 TNISMGSELDNVMEFEDIADNAADAPTETCFM 590 >ECs0568 [R] COG3960 Glyoxylate carboligase Ecs Escherichia coli O157:H7 Length = 593 Score = 625 bits (1611), Expect = e-179, Method: Compositional matrix adjust. Identities = 288/392 (73%), Positives = 335/392 (85%) Query: 1 MLNQSERPLLTIGGGVVNADAAELAVEFAELTGVPVIPTLMAWGAIPDDHPQMAGMVGLQ 60 ML Q+ERP++ GGGV+NADAA L +FAELT VPVIPTLM WG IPDDH MAGMVGLQ Sbjct: 199 MLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQ 258 Query: 61 TSHRYGNATMLASDFVLGIGNRWANRHTGSIEVFTKDRTFVHVDIEPTQIGRVFGPDYGI 120 T+HRYGNAT+LASD V GIGNR+ANRHTGS+E +T+ R VH+DIEPTQIGRV PD GI Sbjct: 259 TAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGI 318 Query: 121 VSDAKAALKLFIEVAKELKAAGNLPDRSAWLADCQERKRTLHRRTHFEEVPIKPQRVYEE 180 VSDAKAAL L +EVA+E++ AG LP R W+ADCQ+RKRTL R+THF+ VP+KPQRVYEE Sbjct: 319 VSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEE 378 Query: 181 MNRAFGRDTCYVSTIGLSQIAAAQFLHVYKDRHWINCGQAGPLGWTISAALGVCAADPQR 240 MN+AFGRD CYV+TIGLSQIAAAQ LHV+KDRHWINCGQAGPLGWTI AALGVCAADP+R Sbjct: 379 MNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKR 438 Query: 241 KVVAISGDYDFQFMIEELAVGAQFNLPYLHVVVNNSYLGLIRQAQRGFEMDYCVQLAFEN 300 VVAISGD+DFQF+IEELAVGAQFN+PY+HV+VNN+YLGLIRQ+QR F+MDYCVQLAFEN Sbjct: 439 NVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFEN 498 Query: 301 INAPELNGYGVDHVAVVEGLGCKAIRVTNPNEIQDAFAVAQRWMAEYRVPVVVEIILERV 360 IN+ E+NGYGVDHV V EGLGCKAIRV P +I AF A+ MA+YRVPVVVE+ILERV Sbjct: 499 INSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERV 558 Query: 361 TNIAMGTEINAINEFEELATKRGHAPTAISLL 392 TNI+MG+E++ + EFE++A APT + Sbjct: 559 TNISMGSELDNVMEFEDIADNAADAPTETCFM 590