BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0048.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1983 [E] COG0133 Tryptophan synthase beta chain Rso Ralstonia... 379 e-105 XF1375 [E] COG0133 Tryptophan synthase beta chain Xfa Xylella fa... 319 5e-87 NMA0904 [E] COG0133 Tryptophan synthase beta chain NmA Neisseria... 315 1e-85 NMB0699 [E] COG0133 Tryptophan synthase beta chain Nme Neisseria... 313 3e-85 aq_706 [E] COG0133 Tryptophan synthase beta chain Aae Aquifex ae... 298 1e-80 >RSc1983 [E] COG0133 Tryptophan synthase beta chain Rso Ralstonia solanacearum Length = 403 Score = 379 bits (972), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/229 (76%), Positives = 196/229 (85%), Gaps = 1/229 (0%) Query: 23 QTAPYNLPDARGHFGQYGGSFVSETLTHALNELRDAYAHYQHDEQFLAEFHTELKHFVGR 82 + A YNLPDA GHFG YGG+FV+ETL+HAL+ELRDAYA YQHD +F+ E+ ELKHFVGR Sbjct: 4 EIAMYNLPDAHGHFGPYGGTFVAETLSHALDELRDAYARYQHDPEFIKEYEYELKHFVGR 63 Query: 83 PSPVYHAKRWSELAGGAQIYFKREDLNHTGAHKINNVIGQALLAKRMGKKRIIAETGAGQ 142 PSP+YHA+R +E GGAQIY KREDLNHTGAHK+NNVIGQALLA+RMGK R+IAETGAGQ Sbjct: 64 PSPIYHARRLTEHCGGAQIYLKREDLNHTGAHKVNNVIGQALLARRMGKPRVIAETGAGQ 123 Query: 143 HGVATATICARFGMECIVYMGSEDVKRQLQNVYRMNLLGATVVPVESGSKTLKDALNEAM 202 HGVATATI AR+GMEC+VYMGSEDV+RQ NVYRM LLGATVVPVESGS+TLKDALNEAM Sbjct: 124 HGVATATIAARYGMECVVYMGSEDVRRQAANVYRMKLLGATVVPVESGSRTLKDALNEAM 183 Query: 203 RDWVTNVESTFYIIGTVAGPHPYPMMVRDFQSSATNASCRCPRSPAASR 251 RDWVTNV TFYIIGTVAGPHPYPMMVRDFQ + C+ A R Sbjct: 184 RDWVTNVADTFYIIGTVAGPHPYPMMVRDFQ-AVIGEECKVQMPELAGR 231 >XF1375 [E] COG0133 Tryptophan synthase beta chain Xfa Xylella fastidiosa 9a5c Length = 449 Score = 319 bits (817), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 149/206 (72%), Positives = 168/206 (81%) Query: 29 LPDARGHFGQYGGSFVSETLTHALNELRDAYAHYQHDEQFLAEFHTELKHFVGRPSPVYH 88 PDARGHFG+YGG FV+ETL L EL AY +HD F+A ++ +LK +VGRPSP+YH Sbjct: 56 FPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYH 115 Query: 89 AKRWSELAGGAQIYFKREDLNHTGAHKINNVIGQALLAKRMGKKRIIAETGAGQHGVATA 148 A+R S GGAQI KREDLNHTGAHKINN IGQALLA RMGK RIIAETGAGQHGVA+A Sbjct: 116 AERLSRKVGGAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASA 175 Query: 149 TICARFGMECIVYMGSEDVKRQLQNVYRMNLLGATVVPVESGSKTLKDALNEAMRDWVTN 208 T+ AR G+EC+VYMG+ D++RQ NVYRM LLGATVVPV SGS TLKDALNEAMRDWVT+ Sbjct: 176 TVAARLGLECVVYMGATDIERQQINVYRMKLLGATVVPVTSGSATLKDALNEAMRDWVTH 235 Query: 209 VESTFYIIGTVAGPHPYPMMVRDFQS 234 V TFYIIGTVAGP PYP MVRDF + Sbjct: 236 VGHTFYIIGTVAGPDPYPRMVRDFNA 261 >NMA0904 [E] COG0133 Tryptophan synthase beta chain NmA Neisseria meningitidis Z2491 Length = 400 Score = 315 bits (806), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 148/212 (69%), Positives = 172/212 (81%) Query: 27 YNLPDARGHFGQYGGSFVSETLTHALNELRDAYAHYQHDEQFLAEFHTELKHFVGRPSPV 86 Y+ PD +G FG++GG FVSETL AL EL DAY ++D +F F +LKH+VGRPSPV Sbjct: 4 YHAPDEKGFFGEHGGLFVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPV 63 Query: 87 YHAKRWSELAGGAQIYFKREDLNHTGAHKINNVIGQALLAKRMGKKRIIAETGAGQHGVA 146 YHA R SE GGAQI+ KREDLNHTGAHK+NN IGQALLAKRMGKKR+IAETGAGQHGVA Sbjct: 64 YHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVA 123 Query: 147 TATICARFGMECIVYMGSEDVKRQLQNVYRMNLLGATVVPVESGSKTLKDALNEAMRDWV 206 +AT+ ARFGM C VYMG++D++RQ+ NV+RM LLGA VV VESGS+TLKDA+NEAMR+WV Sbjct: 124 SATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWV 183 Query: 207 TNVESTFYIIGTVAGPHPYPMMVRDFQSSATN 238 V+ TFYIIGT AGP PYP MVRDFQ N Sbjct: 184 ARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGN 215 >NMB0699 [E] COG0133 Tryptophan synthase beta chain Nme Neisseria meningitidis MC58 Length = 400 Score = 313 bits (802), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 147/212 (69%), Positives = 172/212 (81%) Query: 27 YNLPDARGHFGQYGGSFVSETLTHALNELRDAYAHYQHDEQFLAEFHTELKHFVGRPSPV 86 Y+ PD +G FG++GG +VSETL AL EL DAY ++D +F F +LKH+VGRPSPV Sbjct: 4 YHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPV 63 Query: 87 YHAKRWSELAGGAQIYFKREDLNHTGAHKINNVIGQALLAKRMGKKRIIAETGAGQHGVA 146 YHA R SE GGAQI+ KREDLNHTGAHK+NN IGQALLAKRMGKKR+IAETGAGQHGVA Sbjct: 64 YHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVA 123 Query: 147 TATICARFGMECIVYMGSEDVKRQLQNVYRMNLLGATVVPVESGSKTLKDALNEAMRDWV 206 +AT+ ARFGM C VYMG++D++RQ+ NV+RM LLGA VV VESGS+TLKDA+NEAMR+WV Sbjct: 124 SATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWV 183 Query: 207 TNVESTFYIIGTVAGPHPYPMMVRDFQSSATN 238 V+ TFYIIGT AGP PYP MVRDFQ N Sbjct: 184 ARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGN 215 >aq_706 [E] COG0133 Tryptophan synthase beta chain Aae Aquifex aeolicus Length = 397 Score = 298 bits (763), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 136/208 (65%), Positives = 164/208 (78%) Query: 27 YNLPDARGHFGQYGGSFVSETLTHALNELRDAYAHYQHDEQFLAEFHTELKHFVGRPSPV 86 YN PD RG+FG +GG FV ETL +AL EL + Y + D +F E L+ + GRP+P+ Sbjct: 2 YNYPDERGYFGPFGGKFVPETLMYALEELEEKYRELKSDPEFQKELDYYLREYAGRPTPL 61 Query: 87 YHAKRWSELAGGAQIYFKREDLNHTGAHKINNVIGQALLAKRMGKKRIIAETGAGQHGVA 146 Y A++ ++ GGA+IY KREDL HTGAHKINN IGQ LL KRMGKKR+IAETGAGQHGVA Sbjct: 62 YFAEKLTKYVGGAKIYLKREDLLHTGAHKINNTIGQCLLTKRMGKKRVIAETGAGQHGVA 121 Query: 147 TATICARFGMECIVYMGSEDVKRQLQNVYRMNLLGATVVPVESGSKTLKDALNEAMRDWV 206 TAT A FG+EC+VYMG ED +RQ NV+RM LLGA V V+SGS+TLKDA+NEA+RDWV Sbjct: 122 TATASALFGLECVVYMGEEDAERQALNVFRMKLLGAKVEIVKSGSRTLKDAINEALRDWV 181 Query: 207 TNVESTFYIIGTVAGPHPYPMMVRDFQS 234 TNVEST Y+IG+V GPHP+PM+VRDFQS Sbjct: 182 TNVESTHYVIGSVVGPHPFPMIVRDFQS 209