BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0047.p (221 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1984 [E] COG0135 Phosphoribosylanthranilate isomerase Rso Ral... 247 1e-65 PA3113 [E] COG0135 Phosphoribosylanthranilate isomerase Pae Pseu... 182 5e-46 NMA0890 [E] COG0135 Phosphoribosylanthranilate isomerase NmA Nei... 162 8e-40 TM0139 [E] COG0135 Phosphoribosylanthranilate isomerase Tma Ther... 152 6e-37 lin1670 [E] COG0135 Phosphoribosylanthranilate isomerase Lin Lis... 151 9e-37 >RSc1984 [E] COG0135 Phosphoribosylanthranilate isomerase Rso Ralstonia solanacearum Length = 230 Score = 247 bits (631), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 127/226 (56%), Positives = 159/226 (70%), Gaps = 16/226 (7%) Query: 3 MSRTRIKICGLTRAEDVVAAVAAGADAIGFVFYAKSPRYVTADVAAQLISAAPPFVSTVG 62 + RTRIK+CGLT+ +DV AVA GADAIG VFY SPRYV AA+L A PFV+ G Sbjct: 3 LHRTRIKLCGLTQPDDVDHAVALGADAIGLVFYPPSPRYVATGRAAELARRAGPFVTVTG 62 Query: 63 LFVNAGAEEVAAILQQAPLSLLQFHGDETPEQCAAIAAAVKRPFIRAARIGSSTTPADLI 122 LFVNA A++VA +L Q PL+LLQFHGDETPEQCA IA V P++RA R+ T DL+ Sbjct: 63 LFVNASADDVARVLDQVPLTLLQFHGDETPEQCAEIAGKVGLPWLRALRVQPGT---DLV 119 Query: 123 KYEQDYRSASPYFTGLLLDTLVEQYGGSGKVFDWSLIPEEL---------APRVVLSGGL 173 ++ + +A GLLLD VE YGG G VFDW+LIP + APR+VLSGGL Sbjct: 120 EFADRFAAAQ----GLLLDAFVEGYGGGGHVFDWTLIPPQWLSQSAPPSAAPRLVLSGGL 175 Query: 174 SVQNATDAVQRVRPHAVDISSGVEQAKGIKDAAKIAAFISAVRQAD 219 S QN A++RVRP+AVD+SSG+E A+G+KD A++ AF+ AVR+AD Sbjct: 176 SAQNVAGAIERVRPYAVDVSSGIEAARGVKDRARMTAFVRAVREAD 221 >PA3113 [E] COG0135 Phosphoribosylanthranilate isomerase Pae Pseudomonas aeruginosa Length = 211 Score = 182 bits (462), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 113/215 (52%), Positives = 143/215 (66%), Gaps = 12/215 (5%) Query: 3 MSRTRIKICGLTRAEDVVAAVAAGADAIGFVFYAKSPRYVTADVAAQLISAAPPFVSTVG 62 M RIKICG+TR ED +AA AAGADAIG VFYAKSPR V A +++ A PPFV++VG Sbjct: 1 MPAVRIKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVDIHRAREIVRALPPFVTSVG 60 Query: 63 LFVNAGAEEVAAILQQAPLSLLQFHGDETPEQCAAIAAAVKRPFIRAARIGSSTTPADLI 122 LFVNA E+ IL PL LLQFHGDE E C +RP+++A R+ P D I Sbjct: 61 LFVNASRCELGEILDAVPLDLLQFHGDERAEDCEGH----RRPYLKALRM----KPGDDI 112 Query: 123 KYEQDYRSASPYFTGLLLDTLVEQY-GGSGKVFDWSLIPEELAPRVVLSGGLSVQNATDA 181 +A P G+LLDT VE GG+G FDWSL+P +L +VL+GGL+ N A Sbjct: 113 VGRA---AAYPGAAGILLDTYVEGVPGGTGAAFDWSLVPTDLGKPLVLAGGLTPDNVGRA 169 Query: 182 VQRVRPHAVDISSGVEQAKGIKDAAKIAAFISAVR 216 V++V+P+AVD+S GVE +KGIKDAA++ AF+ AVR Sbjct: 170 VEQVKPYAVDVSGGVEASKGIKDAARVRAFVDAVR 204 >NMA0890 [E] COG0135 Phosphoribosylanthranilate isomerase NmA Neisseria meningitidis Z2491 Length = 208 Score = 162 bits (409), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 91/215 (42%), Positives = 127/215 (59%), Gaps = 18/215 (8%) Query: 3 MSRTRIKICGLTRAEDVVAAVAAGADAIGFVFYAKSPRYVTADVAAQLISAAPPFVSTVG 62 M + R KICG+T ED + A AGADA+G VFY +SPR V A ++ +A PPFVS V Sbjct: 1 MRKIRTKICGITTPEDALYAAHAGADALGLVFYPQSPRAVDIIKAQKITAALPPFVSVVA 60 Query: 63 LFVNAGAEEVAAILQQAPLSLLQFHGDETPEQCAAIAAAVKRPFIRAARIGSSTTPADLI 122 LFVN A+ + IL + P+ ++QFHGDE C RP+I+A R+ +++ Sbjct: 61 LFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQF----HRPYIKAIRVQTAS------ 110 Query: 123 KYEQDYRSASPYF---TGLLLDTLV-EQYGGSGKVFDWSLIPEELAPRVVLSGGLSVQNA 178 D R+A+ F LL D +YGG+G FDW+L+ E VL+GGL+ +N Sbjct: 111 ----DIRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENV 166 Query: 179 TDAVQRVRPHAVDISSGVEQAKGIKDAAKIAAFIS 213 +A++ AVD+S GVE +KG KD AK+AAFI+ Sbjct: 167 DEAIRITGAEAVDVSGGVEASKGKKDPAKVAAFIA 201 >TM0139 [E] COG0135 Phosphoribosylanthranilate isomerase Tma Thermotoga maritima Length = 205 Score = 152 bits (383), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 93/211 (44%), Positives = 122/211 (57%), Gaps = 15/211 (7%) Query: 6 TRIKICGLTRAEDVVAAVAAGADAIGFVFYAKSPRYVTADVAAQLISAAPPFVSTVGLFV 65 R+KICG+T ED + +V +GADA+GFVFY KS RY++ + A ++ PPFV VG+FV Sbjct: 2 VRVKICGITNLEDALFSVESGADAVGFVFYPKSKRYISPEDARRISVELPPFVFRVGVFV 61 Query: 66 NAGAEEVAAILQQAPLSLLQFHGDETPEQCAAIAAAVKRPFIRAARIGSSTTPADLIKYE 125 N E++ + L+ +Q HG+E E C IA + I+A +G S E Sbjct: 62 NEEPEKILDVASYVQLNAVQLHGEEPIELCRKIAERIL--VIKA--VGVSN--------E 109 Query: 126 QDYRSASPYFT-GLLLDTLVEQYGGSGKVFDWSLI-PEELAPR-VVLSGGLSVQNATDAV 182 +D A Y +LLDT +YGGSGK FDWSLI P R +VLSGGL+ +N A+ Sbjct: 110 RDMERALNYREFPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNPENVRSAI 169 Query: 183 QRVRPHAVDISSGVEQAKGIKDAAKIAAFIS 213 VRP AVD+SSGVE G KD I FI Sbjct: 170 DVVRPFAVDVSSGVEAFPGKKDHDSIKMFIK 200 >lin1670 [E] COG0135 Phosphoribosylanthranilate isomerase Lin Listeria innocua Length = 203 Score = 151 bits (382), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 89/212 (41%), Positives = 120/212 (56%), Gaps = 18/212 (8%) Query: 8 IKICGLTRAEDVVAAVAAGADAIGFVFYAKSPRYVTADVAAQLISAAPPFVSTVGLFVNA 67 +KICGL ++ DV AAV GAD IGFVF AKS R VT + A QL PP + VG+FVN Sbjct: 3 VKICGLKKSVDVKAAVENGADMIGFVF-AKSKRQVTIEQAHQLAKNIPPNIKKVGVFVNP 61 Query: 68 GAEEVAAILQQAPLSLLQFHGDETPEQCAAIAAAVKRPFIRAARIGSSTTPADLIKYEQD 127 +E+ A ++ PL ++Q HG E EQ A V I+A + P ++ Y Sbjct: 62 TEDELTAAIKGVPLDIVQLHGQEPTEQADRTDAEV----IKAFPVKEGKLPNNINDYSNA 117 Query: 128 YRSASPYFTGLLLDTLVEQY-GGSGKVFDWSLIPEEL--APRVVLSGGLSVQNATDAVQR 184 Y +LLD E+Y GGSGK FDW + +L +++++GGL+V+N +A+ R Sbjct: 118 Y---------ILLDAPAEEYEGGSGKTFDWDKVNSDLLIKNKLIIAGGLNVENVKEAINR 168 Query: 185 VRPHAVDISSGVEQAKGIKDAAKIAAFISAVR 216 P+AVDISSGVE G KD KI FI + Sbjct: 169 FEPYAVDISSGVE-TNGEKDPEKIKIFIKTAK 199