BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0021.p (246 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1633 [IQR] COG1028 Dehydrogenases with different specificitie... 417 e-116 XF0319 [IQR] COG1028 Dehydrogenases with different specificities... 332 6e-91 CC0511 [IQR] COG1028 Dehydrogenases with different specificities... 253 2e-67 VCA0691 [IQR] COG1028 Dehydrogenases with different specificitie... 233 2e-61 SMc03878 [IQR] COG1028 Dehydrogenases with different specificiti... 230 2e-60 >RSc1633 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 246 Score = 417 bits (1071), Expect = e-116, Method: Compositional matrix adjust. Identities = 198/246 (80%), Positives = 221/246 (89%) Query: 1 MVKRIAYVTGGMGGIGTPICARLAKDGYTVVAGCGPNSARKDKWLASMREQGFDVHASEG 60 M KRIAYVTGGMGGIGT IC RLA+D + VVAGCGPNS RKDKWL RE GFD ASEG Sbjct: 1 MTKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEG 60 Query: 61 NVADWESTKAAFDKVRAEIGEVDVLVNNAGITRDGQFRKMSKSDWDAVIDTNLNSLFNVT 120 NVADW+S+KAAFDKV+AE+GEVDVL+NNAGITRD FRKM++SDWDAVI TNL SLFNVT Sbjct: 61 NVADWDSSKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVT 120 Query: 121 KQVIEGMVDRNWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT 180 KQVI+GMVDR WGRI+NISSVNGQKGQFGQTNYSTAKAG+HGFTMALAQEVATKGVTVNT Sbjct: 121 KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT 180 Query: 181 VSPGYVGTDMVRAIRPEVLEKIVAGIPVKRLAEPEEIASIIAWIASDEGGYATGSDFSLN 240 VSPGY+ TDMV+AIR +VL+KI+ IPVKRL +P EIASI AW+AS+E G++TG+DFSLN Sbjct: 181 VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN 240 Query: 241 GGLHMG 246 GGLHMG Sbjct: 241 GGLHMG 246 >XF0319 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Xfa Xylella fastidiosa 9a5c Length = 246 Score = 332 bits (850), Expect = 6e-91, Method: Compositional matrix adjust. Identities = 150/245 (61%), Positives = 191/245 (77%) Query: 1 MVKRIAYVTGGMGGIGTPICARLAKDGYTVVAGCGPNSARKDKWLASMREQGFDVHASEG 60 M RIAYVT GMG IGT IC +LA++G+TVVAGCGPNS RK WL RE GFD ASEG Sbjct: 1 MTLRIAYVTSGMGSIGTAICQKLARNGHTVVAGCGPNSPRKANWLREQRELGFDFIASEG 60 Query: 61 NVADWESTKAAFDKVRAEIGEVDVLVNNAGITRDGQFRKMSKSDWDAVIDTNLNSLFNVT 120 N ADW+ST +AF KV+AE+GE+DVLVNNAG RD FR+M + DW++VI +NLNSLFN+T Sbjct: 61 NAADWDSTVSAFAKVKAEVGEIDVLVNNAGNNRDMLFRQMGREDWNSVISSNLNSLFNIT 120 Query: 121 KQVIEGMVDRNWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT 180 KQVI+ M RNWGRI+NI SV+ KGQ GQ NY+TAKA +HGFT ALAQEVAT+ VTVNT Sbjct: 121 KQVIDAMTARNWGRIVNIGSVSAHKGQIGQVNYATAKAAMHGFTRALAQEVATRNVTVNT 180 Query: 181 VSPGYVGTDMVRAIRPEVLEKIVAGIPVKRLAEPEEIASIIAWIASDEGGYATGSDFSLN 240 +SPGY+ + + + P+VL+++ +P++RL + EE+A + AW+ SDE Y TG+D+++N Sbjct: 181 ISPGYIASAAISSFPPDVLDRLANSVPMRRLGKAEEVAGLCAWLVSDEAAYVTGADYAVN 240 Query: 241 GGLHM 245 GGL M Sbjct: 241 GGLRM 245 >CC0511 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 240 Score = 253 bits (647), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 131/242 (54%), Positives = 165/242 (68%), Gaps = 5/242 (2%) Query: 4 RIAYVTGGMGGIGTPICARLAKDGYTVVAGCGPNSARKDKWLASMREQGFDVHASEGNVA 63 R+A+VTGG GIG IC RL DG+ V AG N A + + V +GNV Sbjct: 3 RVAFVTGGTRGIGRAICERLIADGHKVAAGYSGNEAAAEACAKEL-----GVMVVKGNVG 57 Query: 64 DWESTKAAFDKVRAEIGEVDVLVNNAGITRDGQFRKMSKSDWDAVIDTNLNSLFNVTKQV 123 +E +AA KV AE+G +D+LVNNAGITRDG KM+ W VI N++S FN+T+ V Sbjct: 58 VFEDCQAAVKKVEAELGPIDILVNNAGITRDGMLHKMTYEQWSEVIRVNMDSAFNMTRPV 117 Query: 124 IEGMVDRNWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNTVSP 183 IEGM DR+WGRIINISS+NGQKGQ GQTNYS AKAG+ GFT ALA E A KGVTVN + P Sbjct: 118 IEGMRDRSWGRIINISSINGQKGQMGQTNYSAAKAGLIGFTKALALENAKKGVTVNVICP 177 Query: 184 GYVGTDMVRAIRPEVLEKIVAGIPVKRLAEPEEIASIIAWIASDEGGYATGSDFSLNGGL 243 GY+ T+MV A+ VL +IVAGIPV RL EEIA +++++A + G+ TG+ +LNGG Sbjct: 178 GYIDTEMVAAVPENVLAQIVAGIPVGRLGRGEEIADMVSFLAGERAGFVTGATLTLNGGQ 237 Query: 244 HM 245 +M Sbjct: 238 YM 239 >VCA0691 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Vch Vibrio cholerae Length = 246 Score = 233 bits (595), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 123/246 (50%), Positives = 160/246 (65%), Gaps = 3/246 (1%) Query: 2 VKRIAYVTGGMGGIGTPICARLAKDGYTVVAG--CGPNSARKDKWLASMREQGFDVHASE 59 +++IA +TG GGIG+ I +L +GY V+A G D W + V E Sbjct: 1 MRKIALITGSKGGIGSAISTQLVSEGYRVIATYYTGNYQCALD-WFNEKQFTEDQVRLLE 59 Query: 60 GNVADWESTKAAFDKVRAEIGEVDVLVNNAGITRDGQFRKMSKSDWDAVIDTNLNSLFNV 119 +V + E K+ E G +DV+VNNAGITRD F+KM W VIDTNLNS+FNV Sbjct: 60 LDVTNTEECAERLAKLLEEEGTIDVVVNNAGITRDSVFKKMPHQAWKEVIDTNLNSVFNV 119 Query: 120 TKQVIEGMVDRNWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVN 179 T+ + M ++ +GRIINISSVNG KGQFGQTNYS AKAG+ GF+ ALA E A GVTVN Sbjct: 120 TQPLFAAMCEKGFGRIINISSVNGLKGQFGQTNYSAAKAGMIGFSKALAAEGARYGVTVN 179 Query: 180 TVSPGYVGTDMVRAIRPEVLEKIVAGIPVKRLAEPEEIASIIAWIASDEGGYATGSDFSL 239 ++PGY T MV +R EVL+ IV +P+KRLA+PEEIA+ ++++ASD Y TG S+ Sbjct: 180 VIAPGYTLTPMVEQMRAEVLQSIVDQVPMKRLAKPEEIANAVSYLASDAAAYITGETLSV 239 Query: 240 NGGLHM 245 NGGL+M Sbjct: 240 NGGLYM 245 >SMc03878 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 241 Score = 230 bits (586), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 123/245 (50%), Positives = 159/245 (64%), Gaps = 6/245 (2%) Query: 2 VKRIAYVTGGMGGIGTPICARLAKDGYTVVAGCGPNSARKDKWLASMREQGFDVHASEGN 61 + R+A VTGG GIG IC L GY V A N R A +E G V+ + + Sbjct: 1 MSRVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAK---AFEQESGIPVY--KWD 55 Query: 62 VADWESTKAAFDKVRAEIGEVDVLVNNAGITRDGQFRKMSKSDWDAVIDTNLNSLFNVTK 121 V+ +++ +V A++G VD+LVNNAGITRD F KM+ W VI TNL +FN+T Sbjct: 56 VSSYQACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPEQWGEVIGTNLTGVFNMTH 115 Query: 122 QVIEGMVDRNWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNTV 181 + GM DR +GRI+NISS+NGQKGQ GQ NYS AKAG G T ALAQE A KG+TVN + Sbjct: 116 PLWSGMRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITVNAI 175 Query: 182 SPGYVGTDMVRAIRPEVL-EKIVAGIPVKRLAEPEEIASIIAWIASDEGGYATGSDFSLN 240 PGY+GT+MVRA+ +VL E+I+ IPV RL EPEE+A + ++ASD+ G+ TGS S N Sbjct: 176 CPGYIGTEMVRAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLASDDAGFITGSTISAN 235 Query: 241 GGLHM 245 GG + Sbjct: 236 GGQYF 240