BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0022.0009.p         (239 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH1646 [H] COG0302 GTP cyclohydrolase I Bha Bacillus halodurans       130   2e-30
HI1447 [H] COG0302 GTP cyclohydrolase I Hin Haemophilus influenzae    126   3e-29
lin2047 [H] COG0302 GTP cyclohydrolase I Lin Listeria innocua         126   4e-29
PM0693 [H] COG0302 GTP cyclohydrolase I Pmu Pasteurella multocida     125   1e-28
BS_mtrA [H] COG0302 GTP cyclohydrolase I Bsu Bacillus subtilis        120   2e-27

>BH1646 [H] COG0302 GTP cyclohydrolase I Bha Bacillus halodurans
          Length = 188

 Score =  130 bits (328), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 78/185 (42%), Positives = 106/185 (57%), Gaps = 7/185 (3%)

Query: 55  EVQAKLAGVLESLVIDVDSDHNTQDTAKRVAKMYLQEVFRGRYLPAPPVTEFPNI--ERL 112
           ++Q  +  +LE++  D  +    +DT KRVAKMY +EVF G  L   P   F  I  E  
Sbjct: 8   KIQQAVVMILEAIGED-PAREGLEDTPKRVAKMY-EEVFAG--LNQDPKEHFATIFGEDH 63

Query: 113 NELMIVGPITVRSACSHHLCPIMGKVWVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEE 172
            EL++V  I   S C HHL P  GK  VG +P     + GLSK AR +E +  RPQ+QE 
Sbjct: 64  EELVLVKDIPFFSMCEHHLVPFFGKAHVGYIPK-GGKVTGLSKLARAVEAVARRPQLQER 122

Query: 173 AVSQVAGLLMEKLQPDGLAIVMEADHFCMHWRGVKDTESKMINSVMRGSFLRDANLRREF 232
             S VA  L+E L+P G+ +V+EA+H CM  RGVK   +  + S +RG+F  DA  R E 
Sbjct: 123 ITSTVADALVETLEPHGVIVVVEAEHMCMTMRGVKKPGAATVTSAVRGTFANDAAARAEV 182

Query: 233 LALIR 237
           L+LI+
Sbjct: 183 LSLIK 187


>HI1447 [H] COG0302 GTP cyclohydrolase I Hin Haemophilus influenzae
          Length = 218

 Score =  126 bits (317), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 62/166 (37%), Positives = 97/166 (58%), Gaps = 3/166 (1%)

Query: 74  DHNTQDTAKRVAKMYLQEVFRG-RYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLC 132
           D + ++T  R+AKM++ E+F G  Y   P +T+  N  +++E++ V  IT+ S C HH  
Sbjct: 55  DDSLEETPNRLAKMFIDEIFSGMDYANFPKMTKIKNQMKVSEMVQVNDITLTSTCEHHFV 114

Query: 133 PIMGKVWVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAI 192
            I GKV V   P +   +IGLSK  R++ +   RPQ+QE    Q+       L+ D +A+
Sbjct: 115 TIDGKVCVAYYPKDW--VIGLSKINRIVSFFAQRPQVQERLTEQLLTAFQTILETDDVAV 172

Query: 193 VMEADHFCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIRK 238
            ++A HFC+  RG++DT S  + S   G FL D + R+EFLA ++K
Sbjct: 173 YVKATHFCVKARGIRDTNSYTVTSAYGGVFLEDRDTRKEFLATVQK 218


>lin2047 [H] COG0302 GTP cyclohydrolase I Lin Listeria innocua
          Length = 189

 Score =  126 bits (316), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 70/161 (43%), Positives = 97/161 (60%), Gaps = 6/161 (3%)

Query: 79  DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNI--ERLNELMIVGPITVRSACSHHLCPIMG 136
           DT  RVA+MY +EVF G  L   P   F  I  E+  EL++V  I   S C HHL P  G
Sbjct: 31  DTPMRVARMY-EEVFAG--LKKDPSVHFDTIFEEQHEELVLVKDIRFSSMCEHHLVPFFG 87

Query: 137 KVWVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEA 196
              V  +P ++  + GLSK AR+++ +  RPQ+QE   + VA ++M+KL+P G+ ++MEA
Sbjct: 88  VAHVAYLP-QNGRVAGLSKLARVVDDVSRRPQLQERITTTVAEIMMDKLKPLGVMVIMEA 146

Query: 197 DHFCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIR 237
           +H CM  RGV    +K I S +RG+F  D  LR E LALI+
Sbjct: 147 EHMCMTIRGVNKPGTKTITSAVRGAFKNDDKLRSEVLALIK 187


>PM0693 [H] COG0302 GTP cyclohydrolase I Pmu Pasteurella multocida
          Length = 218

 Score =  125 bits (313), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 66/190 (34%), Positives = 107/190 (56%), Gaps = 4/190 (2%)

Query: 50  DALQAEVQAKLAGVLESLVIDVDSDHNTQDTAKRVAKMYLQEVFRG-RYLPAPPVTEFPN 108
           D  +A ++  +  V++ + +D+  D + ++T  R+AKM++ E+F G  Y   P +T   N
Sbjct: 32  DTRRAGIEQHMREVMKLIGLDL-RDDSLEETPVRLAKMFVDEIFSGLDYANFPKITNIEN 90

Query: 109 IERLNELMIVGPITVRSACSHHLCPIMGKVWVGVMPNEHSNLIGLSKYARLIEWIMSRPQ 168
             +++E+++V  +T+ S C HH   I G V V   P +   +IGLSK  R++ +   RPQ
Sbjct: 91  RMKVSEMVLVNDVTLTSTCEHHFVTIDGMVSVAYYPKKW--VIGLSKINRIVAFFAQRPQ 148

Query: 169 IQEEAVSQVAGLLMEKLQPDGLAIVMEADHFCMHWRGVKDTESKMINSVMRGSFLRDANL 228
           +QE    Q+       L+ D +A+ ++A HFC+  RG+KDT S  + S   G FL D   
Sbjct: 149 VQERLTEQILLAFQTILETDDVAVYVKATHFCVKCRGIKDTNSYTVTSAFGGVFLDDRET 208

Query: 229 RREFLALIRK 238
           R+EFL LI K
Sbjct: 209 RKEFLTLINK 218


>BS_mtrA [H] COG0302 GTP cyclohydrolase I Bsu Bacillus subtilis
          Length = 190

 Score =  120 bits (302), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 70/162 (43%), Positives = 90/162 (55%), Gaps = 6/162 (3%)

Query: 79  DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNI--ERLNELMIVGPITVRSACSHHLCPIMG 136
           DT KRVAKMY  EVF G  L   P   F  I  E   EL++V  I   S C HHL P  G
Sbjct: 31  DTPKRVAKMYA-EVFSG--LNEDPKEHFQTIFGENHEELVLVKDIAFHSMCEHHLVPFYG 87

Query: 137 KVWVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEA 196
           K  V  +P     + GLSK AR +E +  RPQ+QE   S +A  ++E L P G+ +V+EA
Sbjct: 88  KAHVAYIPR-GGKVTGLSKLARAVEAVAKRPQLQERITSTIAESIVETLDPHGVMVVVEA 146

Query: 197 DHFCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIRK 238
           +H CM  RGV+   +K + S +RG F  DA  R E L  I++
Sbjct: 147 EHMCMTMRGVRKPGAKTVTSAVRGVFKDDAAARAEVLEHIKR 188