BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0005.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 356 5e-98 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 349 7e-96 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 349 8e-96 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 349 8e-96 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 333 4e-91 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 356 bits (914), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 179/340 (52%), Positives = 242/340 (71%), Gaps = 2/340 (0%) Query: 22 EGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLAMMV 81 +GLP +R AI+ + + + +A LD IAN ALP +ARDLNT+PA S+W+V AYQLA+ + Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 82 SLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMSVNT 141 SLL +A+LG+I+GYRR+Y GL +F+ SL CA++ SL LT AR LQG G A +MSVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 142 ALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIGLVM 201 ALIR IYP LGRG+GINTLIVA+S GPS+A+ +L++A W WLFA+NVP+G++ + Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 202 AVPSLP--YTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALVCGY 259 + LP T + + FDI S +LNA FGLLI AI + +P+V+ + VA L+ G+ Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 260 LLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 +RR+ + P+LPVDL R P+F+LS T++ SFAAQ LA VSLPFF LGR +V Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 320 GLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLAE 359 GLL+TPWP+A ++APIAGR+ + Y AG+LGG GLA+ A Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFAS 346 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 349 bits (895), Expect = 7e-96, Method: Compositional matrix adjust. Identities = 180/342 (52%), Positives = 244/342 (71%), Gaps = 2/342 (0%) Query: 19 IAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLA 78 + +GLP +R AI+T++I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMS 138 +++SLL + LG++ GYRRIY GL +F +SL CA++ SL LT+AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMS 160 Query: 139 VNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIG 198 VNTALIR IYP R LGRG+GIN+ IVA+S GP++A+ IL+IA W WLF +NVPLGII Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 LVMAVPSLP--YTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALV 256 L++A+ LP + S FD+ SA++NA FGLLI A+ A + +++ E V +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G +RR+ S P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 VE GLL+TPWP+A +MAP+AG + + AG+LG GL ++A Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMA 382 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 349 bits (895), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 180/342 (52%), Positives = 244/342 (71%), Gaps = 2/342 (0%) Query: 19 IAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLA 78 + +GLP +R AI+T++I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMS 138 +++SLL + LG++ GYRRIY GL +F +SL CA++ SL LT+AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIG 198 VNTALIR IYP R LGRG+GIN+ IVA+S GP++A+ IL+IA W WLF +NVPLGII Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 LVMAVPSLP--YTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALV 256 L++A+ LP + S FD+ SA++NA FGLLI A+ A + +++ E V +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G +RR+ S P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 VE GLL+TPWP+A +MAP+AG + + AG+LG GL ++A Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMA 382 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 349 bits (895), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 180/342 (52%), Positives = 244/342 (71%), Gaps = 2/342 (0%) Query: 19 IAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLA 78 + +GLP +R AI+T++I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMS 138 +++SLL + LG++ GYRRIY GL +F +SL CA++ SL LT+AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIG 198 VNTALIR IYP R LGRG+GIN+ IVA+S GP++A+ IL+IA W WLF +NVPLGII Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 LVMAVPSLP--YTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALV 256 L++A+ LP + S FD+ SA++NA FGLLI A+ A + +++ E V +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G +RR+ S P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 VE GLL+TPWP+A +MAP+AG + + AG+LG GL ++A Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMA 382 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 333 bits (855), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 175/339 (51%), Positives = 242/339 (71%), Gaps = 2/339 (0%) Query: 22 EGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLAMMV 81 +GLP +R AI+T++I + +A LD AIAN ALP +A DL+ +PA+S+WIV AYQ+A++V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 82 SLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMSVNT 141 SLL L+ LG++ GY RIY GL +F +SL CA++ SL LT+AR QG GGA +MSVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 142 ALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIGLVM 201 ALIR IYP R LGRG+GIN+ IVA+S GP++A+ IL+I+ W WLF +NVPLGII L++ Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 202 AVPSLPYT--PKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALVCGY 259 A+ LP + FD+ SA++NA FGLLI A+ A + +++ E + +V G+ Sbjct: 187 AIRFLPANIAHDTKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVVVGF 246 Query: 260 LLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 +RR+ S P P+LP+DL R P+FSLS T++CSF AQ LA VSLPF+ LGRS+VE Sbjct: 247 FFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRSEVET 306 Query: 320 GLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 GLL+TPWP+A +MAP+AG + + AG+LG G+ ++A Sbjct: 307 GLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMA 345