BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0132.p (250 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3128 [IQR] COG1028 Dehydrogenases with different specificities... 323 2e-88 VCA0301 [IQR] COG1028 Dehydrogenases with different specificitie... 313 2e-85 mll4297 [IQR] COG1028 Dehydrogenases with different specificitie... 311 8e-85 ygfF [IQR] COG1028 Dehydrogenases with different specificities (... 300 2e-81 SMc02486 [IQR] COG1028 Dehydrogenases with different specificiti... 270 3e-72 >PA3128 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 248 Score = 323 bits (828), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 160/248 (64%), Positives = 202/248 (81%), Gaps = 1/248 (0%) Query: 3 QPVIIVTGGSRGIGAAVAQSAAARGYIDXAISYVSNRAAADAVVEGIVKAGGRAIAVKSD 62 + V+++TG SRGIGAA A AA RGY ++Y+ NR AA+A+ + I + GG A+AV +D Sbjct: 2 RNVMLITGASRGIGAATALLAAERGYA-VVLNYLRNREAAEALRQRIERQGGEALAVAAD 60 Query: 63 VAVEADILHLFQTVDKELGTLAALVNNAGILEHQSRFDELSADRINRVLLTNVTGSLLCA 122 VA E D+ LF ++D+ G L LVNNAG+LE Q+R + + A R++RV TNVTGS LCA Sbjct: 61 VAEEGDVERLFASIDERFGRLDVLVNNAGMLEAQTRLENIDAARLHRVFATNVTGSFLCA 120 Query: 123 REAVRRMSTRHGGKGGAIVNLSSMAARLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGI 182 REAV+R+STRHGG+GG+IVN+SSMA+RLG P EY+DYAA+KGAID+ TIGLA+EVAAEGI Sbjct: 121 REAVKRLSTRHGGRGGSIVNVSSMASRLGSPNEYIDYAAAKGAIDSMTIGLAREVAAEGI 180 Query: 183 RVNAIRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAEEVANAVLWLLSDEASYATGT 242 RVNA+RPGLI T+IHASGGE GR++RLK +P+ RGG+AEEVA A+LWL SDEASY+TGT Sbjct: 181 RVNAVRPGLIDTEIHASGGEPGRIERLKGGIPLGRGGTAEEVARAILWLASDEASYSTGT 240 Query: 243 FIDVSGGR 250 FIDVSGGR Sbjct: 241 FIDVSGGR 248 >VCA0301 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Vch Vibrio cholerae Length = 250 Score = 313 bits (802), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 149/247 (60%), Positives = 193/247 (78%), Gaps = 1/247 (0%) Query: 3 QPVIIVTGGSRGIGAAVAQSAAARGYIDXAISYVSNRAAADAVVEGIVKAGGRAIAVKSD 62 Q V+++TGGSRGIGAA A+ A G+ I+Y SN AA+ +VE I GG IAV++D Sbjct: 4 QKVVVITGGSRGIGAATAKLFAQNGF-SVCINYKSNAEAANTLVEEIKALGGHCIAVQAD 62 Query: 63 VAVEADILHLFQTVDKELGTLAALVNNAGILEHQSRFDELSADRINRVLLTNVTGSLLCA 122 V+ E+D++ LF+TVD+ELG ++ LVNNAGIL+ Q R DE+SA+RIN +L+ NVTG LC Sbjct: 63 VSKESDVVKLFETVDQELGVVSVLVNNAGILKKQMRLDEMSAERINSILINNVTGYFLCC 122 Query: 123 REAVRRMSTRHGGKGGAIVNLSSMAARLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGI 182 RE V+RMSTRHGG GG IVN+SS AAR G P EY+DYAASKGAID T GL+ EVAAEGI Sbjct: 123 RETVKRMSTRHGGFGGVIVNVSSGAARTGSPNEYIDYAASKGAIDTLTKGLSLEVAAEGI 182 Query: 183 RVNAIRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAEEVANAVLWLLSDEASYATGT 242 RVN +RPGLIYTD+HA GGE R++RLK+ +PM+RGG +EVA A+ WL S+++S++TG Sbjct: 183 RVNCVRPGLIYTDMHADGGEPDRIERLKNKIPMQRGGLPDEVAEAIYWLSSEKSSFSTGN 242 Query: 243 FIDVSGG 249 F+D++GG Sbjct: 243 FLDLAGG 249 >mll4297 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 251 Score = 311 bits (797), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 162/248 (65%), Positives = 196/248 (79%), Gaps = 1/248 (0%) Query: 3 QPVIIVTGGSRGIGAAVAQSAAARGYIDXAISYVSNRAAADAVVEGIVKAGGRAIAVKSD 62 Q V++VTGGSRGIGAAV + A GY A++Y SNRAAADA+V I AGG A AVK D Sbjct: 5 QKVLLVTGGSRGIGAAVCRLGAKAGY-RVAVNYASNRAAADALVAEIKAAGGDAFAVKGD 63 Query: 63 VAVEADILHLFQTVDKELGTLAALVNNAGILEHQSRFDELSADRINRVLLTNVTGSLLCA 122 V EADI+ +F+ VD+ G L A VNNAGI++ ++R DE+SA R+ R++ NV GS+LCA Sbjct: 64 VGGEADIIAIFEAVDRSYGRLDAFVNNAGIVDAKARVDEMSAARLERMMRINVVGSILCA 123 Query: 123 REAVRRMSTRHGGKGGAIVNLSSMAARLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGI 182 REAV+RMSTRHGGKGGAIVN+SS AA LG P YVDYAASKGAID FT+GLA+EVA EGI Sbjct: 124 REAVKRMSTRHGGKGGAIVNISSAAAVLGAPDNYVDYAASKGAIDTFTVGLAREVALEGI 183 Query: 183 RVNAIRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAEEVANAVLWLLSDEASYATGT 242 RVNA+RPG+I TDIHASGG+ RV ++D +PMKR G+A+EVA AVL+LLSD ASY TG Sbjct: 184 RVNAVRPGIIDTDIHASGGQPDRVALIQDTLPMKRAGTADEVAAAVLYLLSDAASYTTGA 243 Query: 243 FIDVSGGR 250 ++VSGGR Sbjct: 244 ILNVSGGR 251 >ygfF [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Eco Escherichia coli K12 Length = 247 Score = 300 bits (768), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 147/246 (59%), Positives = 189/246 (76%), Gaps = 1/246 (0%) Query: 5 VIIVTGGSRGIGAAVAQSAAARGYIDXAISYVSNRAAADAVVEGIVKAGGRAIAVKSDVA 64 + +VTGGSRGIG A A A GY A++Y N AA V+ I +AGG+A +++D++ Sbjct: 3 IALVTGGSRGIGRATALLLAQEGYT-VAVNYQQNLHAAQEVMNLITQAGGKAFVLQADIS 61 Query: 65 VEADILHLFQTVDKELGTLAALVNNAGILEHQSRFDELSADRINRVLLTNVTGSLLCARE 124 E ++ +F +D+ LAALVNNAGIL Q + L+A+RINRVL TNVTG LC RE Sbjct: 62 DENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCRE 121 Query: 125 AVRRMSTRHGGKGGAIVNLSSMAARLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGIRV 184 AV+RM+ ++GG GGAIVN+SS+A+RLG PGEYVDYAASKGAID T GL+ EVAA+GIRV Sbjct: 122 AVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASKGAIDTLTTGLSLEVAAQGIRV 181 Query: 185 NAIRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAEEVANAVLWLLSDEASYATGTFI 244 N +RPG IYT++HASGGE GRVDR+K +PM+RGG AEEVA A++WLLSD+ASY TG+FI Sbjct: 182 NCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQAEEVAQAIVWLLSDKASYVTGSFI 241 Query: 245 DVSGGR 250 D++GG+ Sbjct: 242 DLAGGK 247 >SMc02486 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 250 Score = 270 bits (689), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 146/247 (59%), Positives = 188/247 (76%), Gaps = 1/247 (0%) Query: 4 PVIIVTGGSRGIGAAVAQSAAARGYIDXAISYVSNRAAADAVVEGIVKAGGRAIAVKSDV 63 PV++VTGGSRGIGAAVA +AA+ G+ A++Y SNR AA+ VV I +AGG A++V+ +V Sbjct: 5 PVLLVTGGSRGIGAAVALAAASEGW-RVAVNYASNRDAAEDVVRRIAEAGGTAVSVEGNV 63 Query: 64 AVEADILHLFQTVDKELGTLAALVNNAGILEHQSRFDELSADRINRVLLTNVTGSLLCAR 123 E + +F VD G L LVNNAGI+ R DE+S +RI ++ NVTGS+ CA Sbjct: 64 GREEGVRAIFAAVDTAFGRLDGLVNNAGIIGPPQRVDEVSPERIEQLFRVNVTGSIRCAA 123 Query: 124 EAVRRMSTRHGGKGGAIVNLSSMAARLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGIR 183 EAV RMS RHGG+GG+IVNLSS+AA LG PG+YVDYAA+KGAID+FT+GLA+EVA EGIR Sbjct: 124 EAVLRMSARHGGRGGSIVNLSSIAAVLGAPGQYVDYAATKGAIDSFTVGLAREVATEGIR 183 Query: 184 VNAIRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAEEVANAVLWLLSDEASYATGTF 243 VNA+RPG+I T+IHASGG R L +P++R G+A EVA+A+L+LLSD+A+Y TGT Sbjct: 184 VNAVRPGIIDTEIHASGGLPDRARDLAPTIPIQRPGTAGEVADAILYLLSDKATYVTGTI 243 Query: 244 IDVSGGR 250 + VSGGR Sbjct: 244 LTVSGGR 250