BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0117.p (442 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0075 [GEPR] COG0477 Permeases of the major facilitator superf... 662 0.0 PA0229 [GEPR] COG0477 Permeases of the major facilitator superfa... 622 e-178 STM2654 [GEPR] COG0477 Permeases of the major facilitator superf... 584 e-166 ECs3454 [GEPR] COG0477 Permeases of the major facilitator superf... 564 e-160 kgtP [GEPR] COG0477 Permeases of the major facilitator superfami... 563 e-160 >RSp0075 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 437 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/437 (73%), Positives = 371/437 (84%), Gaps = 1/437 (0%) Query: 5 VSTTSASATSSVAAGPSTTKQRILAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDT 64 +ST +A A+ +V A P T++RI AI+GASSGNLVEWFDFYVY+FC++YFAPAFFP G+T Sbjct: 1 MSTPAAQASQAVMA-PHDTRRRIFAIVGASSGNLVEWFDFYVYAFCSLYFAPAFFPSGNT 59 Query: 65 TTQLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMMISVLMMCGGSLMIAFLPTYAV 124 TTQL+NTAGVFAAGFLMRPIGGWLFGRIAD+HGR+ +MMISVLMMCGGSL+IA LP YA Sbjct: 60 TTQLMNTAGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPIYAQ 119 Query: 125 IGTAAPFLLLVARLFQGLSVGGEYGTSATYMSEIAPKNNRGFFASFQYVTLIGGQLLAVL 184 IG APFLLLVARLFQGLSVGGEYGTSATYMSE+A K RGFFASFQYVTLIGGQL A+L Sbjct: 120 IGALAPFLLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALL 179 Query: 185 VLVAMQQTLSNEELRAWGWRVPFVLGAFGALIALYLRKSLTETATAETRTKKEAGTFAGL 244 VLV +QQ LS EL+AWGWR+PFV+GA AL++LYLR+SL ET + +R K AGT G Sbjct: 180 VLVILQQVLSTAELKAWGWRIPFVVGALSALVSLYLRRSLDETQSTASREAKHAGTIRGA 239 Query: 245 WKHKRAFFTVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDAKTASAVMTGALFVYMILQPV 304 W+HK AF V+GFTAGGSL+FYTFTTYMQKYLVNTAGM+ KTAS VMT ALFVYM LQPV Sbjct: 240 WQHKGAFLRVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMALQPV 299 Query: 305 FGALSDKIGRRNMMLLFGVLGTLCTVPILHMLKDVTDPYAAFGLAILALCIVSFYTSISG 364 FGALSD+IGRR M+LFGV L TVP++ L VT+PYAAFGL AL I+SFYTSISG Sbjct: 300 FGALSDRIGRRMSMILFGVGAVLFTVPLMRALGSVTNPYAAFGLVTAALAIISFYTSISG 359 Query: 365 LIKAEMFPPEVRALCVGLSYAVGNALFGGSAEFVALSFKAAGMESNFYWYVSIMCAIALL 424 LIKAEMFPPEVRA+ VGLSYA+ NA+FGGSAE+VAL FK+AG ES FYWYV+ +CA++L+ Sbjct: 360 LIKAEMFPPEVRAMGVGLSYAIANAVFGGSAEYVALWFKSAGRESTFYWYVTTLCAVSLI 419 Query: 425 ITFRMRDPSKVGYLKDE 441 +++ M DPSK GYL+ E Sbjct: 420 VSYTMPDPSKEGYLRHE 436 >PA0229 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 432 Score = 622 bits (1603), Expect = e-178, Method: Compositional matrix adjust. Identities = 318/418 (76%), Positives = 360/418 (86%) Query: 24 KQRILAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDTTTQLLNTAGVFAAGFLMRP 83 ++RI AI+GASSGNLVEWFDFYVY+FCAIYFAPAFFP + T QLLNTAGVFAAGFLMRP Sbjct: 14 RKRIFAIVGASSGNLVEWFDFYVYAFCAIYFAPAFFPSDNPTVQLLNTAGVFAAGFLMRP 73 Query: 84 IGGWLFGRIADKHGRKTSMMISVLMMCGGSLMIAFLPTYAVIGTAAPFLLLVARLFQGLS 143 IGGW+FGRIADKHGRKT+M+ISV+MMC GSL IA +PTYA IGT AP LLL+AR+FQGLS Sbjct: 74 IGGWMFGRIADKHGRKTAMLISVVMMCAGSLAIACMPTYASIGTLAPALLLLARMFQGLS 133 Query: 144 VGGEYGTSATYMSEIAPKNNRGFFASFQYVTLIGGQLLAVLVLVAMQQTLSNEELRAWGW 203 VGGEYGTSATYMSE+A K RGFFASFQYVTLIGGQLLAVLV+V +QQ LS +ELRAWGW Sbjct: 134 VGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVILQQLLSEDELRAWGW 193 Query: 204 RVPFVLGAFGALIALYLRKSLTETATAETRTKKEAGTFAGLWKHKRAFFTVVGFTAGGSL 263 R+PFV+GA A+IAL+LR+SL ETA+ T +KE+GTFA L+KHKRAFFTV+GFTAGGSL Sbjct: 194 RIPFVIGAITAVIALWLRRSLNETASKSTLERKESGTFAELFKHKRAFFTVLGFTAGGSL 253 Query: 264 MFYTFTTYMQKYLVNTAGMDAKTASAVMTGALFVYMILQPVFGALSDKIGRRNMMLLFGV 323 +FYTFTTYMQKYLVNTAGM AKTASAVMT AL YM++QP+FG LSD+IGR+ ML FG Sbjct: 254 IFYTFTTYMQKYLVNTAGMSAKTASAVMTFALLAYMLMQPLFGMLSDRIGRKTSMLWFGT 313 Query: 324 LGTLCTVPILHMLKDVTDPYAAFGLAILALCIVSFYTSISGLIKAEMFPPEVRALCVGLS 383 LGTLCT+PIL LK V+ PY AF L ILAL IVS YTSISGLIKAEMFPPEVRAL VG+S Sbjct: 314 LGTLCTLPILLALKTVSSPYMAFFLIILALAIVSLYTSISGLIKAEMFPPEVRALGVGVS 373 Query: 384 YAVGNALFGGSAEFVALSFKAAGMESNFYWYVSIMCAIALLITFRMRDPSKVGYLKDE 441 YAVGNA+FGGSAE+VAL K+ GME+ FYWYVS MC +ALL+ + D KV YL DE Sbjct: 374 YAVGNAIFGGSAEYVALGLKSVGMENVFYWYVSAMCLLALLVCVSLPDLRKVSYLNDE 431 >STM2654 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 584 bits (1505), Expect = e-166, Method: Compositional matrix adjust. Identities = 292/411 (71%), Positives = 340/411 (82%) Query: 24 KQRILAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDTTTQLLNTAGVFAAGFLMRP 83 ++RI AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+TTTQLL TAGVFAAGFLMRP Sbjct: 19 RRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRP 78 Query: 84 IGGWLFGRIADKHGRKTSMMISVLMMCGGSLMIAFLPTYAVIGTAAPFLLLVARLFQGLS 143 IGGWLFGRIAD+ GRK SM+ISV MMC GSL+IA LP Y IGT AP LLL+ARLFQGLS Sbjct: 79 IGGWLFGRIADRRGRKASMLISVCMMCMGSLVIACLPGYDTIGTWAPALLLIARLFQGLS 138 Query: 144 VGGEYGTSATYMSEIAPKNNRGFFASFQYVTLIGGQLLAVLVLVAMQQTLSNEELRAWGW 203 VGGEYGTSATYMSE+A + +GFFASFQYVTLIGGQLLA+LV+V +QQ L + ELRAWGW Sbjct: 139 VGGEYGTSATYMSEVALEGRKGFFASFQYVTLIGGQLLALLVVVILQQVLDDAELRAWGW 198 Query: 204 RVPFVLGAFGALIALYLRKSLTETATAETRTKKEAGTFAGLWKHKRAFFTVVGFTAGGSL 263 R+PF LGA A++AL+LR+ L ET+ ETR KEAG+ GLW++++AF V+GFTA GSL Sbjct: 199 RIPFALGAVLAVVALWLRRQLDETSKHETRALKEAGSLKGLWRNRKAFLMVLGFTAAGSL 258 Query: 264 MFYTFTTYMQKYLVNTAGMDAKTASAVMTGALFVYMILQPVFGALSDKIGRRNMMLLFGV 323 FYTFTTYMQKYLVNTAGM A AS +MT AL V+M++QP+FGALSDKIGRR ML FG Sbjct: 259 CFYTFTTYMQKYLVNTAGMHANVASGIMTAALCVFMLVQPLFGALSDKIGRRTSMLCFGA 318 Query: 324 LGTLCTVPILHMLKDVTDPYAAFGLAILALCIVSFYTSISGLIKAEMFPPEVRALCVGLS 383 L TL TVPIL L++VT PYAAF L I AL IVSFYTSISG++KAEMFP +VRAL VGLS Sbjct: 319 LATLFTVPILSALQNVTSPYAAFALVICALLIVSFYTSISGILKAEMFPAQVRALGVGLS 378 Query: 384 YAVGNALFGGSAEFVALSFKAAGMESNFYWYVSIMCAIALLITFRMRDPSK 434 YAV NALFGGSAE+VALS K+ GMES+F+WYV+ M +A L++ + K Sbjct: 379 YAVANALFGGSAEYVALSLKSVGMESSFFWYVTAMAVLAFLVSLMLHRKGK 429 >ECs3454 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 432 Score = 564 bits (1454), Expect = e-160, Method: Compositional matrix adjust. Identities = 291/434 (67%), Positives = 348/434 (80%), Gaps = 6/434 (1%) Query: 1 MTQTVSTTSASATSSVAAGPSTTKQRILAILGASSGNLVEWFDFYVYSFCAIYFAPAFFP 60 M ++ T + TSS T++RI AI+GASSGNLVEWFDFYVYSFC++YFA FFP Sbjct: 1 MAESTVTADSKLTSS------DTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFP 54 Query: 61 KGDTTTQLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMMISVLMMCGGSLMIAFLP 120 G+TTTQLL TAGVFAAGFLMRPIGGWLFGRIADKHGRK SM++SV MMC GSL+IA LP Sbjct: 55 SGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLP 114 Query: 121 TYAVIGTAAPFLLLVARLFQGLSVGGEYGTSATYMSEIAPKNNRGFFASFQYVTLIGGQL 180 Y IGT AP LLL+ARLFQGLSVGGEYGTSATYMSE+A + +GF+ASFQYVTLIGGQL Sbjct: 115 GYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQL 174 Query: 181 LAVLVLVAMQQTLSNEELRAWGWRVPFVLGAFGALIALYLRKSLTETATAETRTKKEAGT 240 LA+LV+V +Q T+ + LR WGWR+PF LGA A++AL+LR+ L ET+ ETR KEAG+ Sbjct: 175 LALLVVVVLQHTMEDSALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGS 234 Query: 241 FAGLWKHKRAFFTVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDAKTASAVMTGALFVYMI 300 GLW+++RAF V+GFTA GSL FYTFTTYMQKYLVNTAGM A AS +MT ALFV+M+ Sbjct: 235 LKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFML 294 Query: 301 LQPVFGALSDKIGRRNMMLLFGVLGTLCTVPILHMLKDVTDPYAAFGLAILALCIVSFYT 360 +QP+ GALSDKIGRR ML FG L + TVPIL L++V+ PYAAFGL + AL IVSFYT Sbjct: 295 IQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYT 354 Query: 361 SISGLIKAEMFPPEVRALCVGLSYAVGNALFGGSAEFVALSFKAAGMESNFYWYVSIMCA 420 SISG++KAEMFP +VRAL VGLSYAV NA+FGGSAE+VALS K+ GME+ F+WYV++M Sbjct: 355 SISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAV 414 Query: 421 IALLITFRMRDPSK 434 +A L++ + K Sbjct: 415 VAFLVSLMLHRKGK 428 >kgtP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 432 Score = 563 bits (1452), Expect = e-160, Method: Compositional matrix adjust. Identities = 291/434 (67%), Positives = 348/434 (80%), Gaps = 6/434 (1%) Query: 1 MTQTVSTTSASATSSVAAGPSTTKQRILAILGASSGNLVEWFDFYVYSFCAIYFAPAFFP 60 M ++ T + TSS T++RI AI+GASSGNLVEWFDFYVYSFC++YFA FFP Sbjct: 1 MAESTVTADSKLTSS------DTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFP 54 Query: 61 KGDTTTQLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMMISVLMMCGGSLMIAFLP 120 G+TTTQLL TAGVFAAGFLMRPIGGWLFGRIADKHGRK SM++SV MMC GSL+IA LP Sbjct: 55 SGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLP 114 Query: 121 TYAVIGTAAPFLLLVARLFQGLSVGGEYGTSATYMSEIAPKNNRGFFASFQYVTLIGGQL 180 Y IGT AP LLL+ARLFQGLSVGGEYGTSATYMSE+A + +GF+ASFQYVTLIGGQL Sbjct: 115 GYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQL 174 Query: 181 LAVLVLVAMQQTLSNEELRAWGWRVPFVLGAFGALIALYLRKSLTETATAETRTKKEAGT 240 LA+LV+V +Q T+ + LR WGWR+PF LGA A++AL+LR+ L ET+ ETR KEAG+ Sbjct: 175 LALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGS 234 Query: 241 FAGLWKHKRAFFTVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDAKTASAVMTGALFVYMI 300 GLW+++RAF V+GFTA GSL FYTFTTYMQKYLVNTAGM A AS +MT ALFV+M+ Sbjct: 235 LKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFML 294 Query: 301 LQPVFGALSDKIGRRNMMLLFGVLGTLCTVPILHMLKDVTDPYAAFGLAILALCIVSFYT 360 +QP+ GALSDKIGRR ML FG L + TVPIL L++V+ PYAAFGL + AL IVSFYT Sbjct: 295 IQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYT 354 Query: 361 SISGLIKAEMFPPEVRALCVGLSYAVGNALFGGSAEFVALSFKAAGMESNFYWYVSIMCA 420 SISG++KAEMFP +VRAL VGLSYAV NA+FGGSAE+VALS K+ GME+ F+WYV++M Sbjct: 355 SISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAV 414 Query: 421 IALLITFRMRDPSK 434 +A L++ + K Sbjct: 415 VAFLVSLMLHRKGK 428