BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0083.p (532 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0663 [GEPR] COG0477 Permeases of the major facilitator superf... 655 0.0 DRA0061 [GEPR] COG0477 Permeases of the major facilitator superf... 228 4e-59 BS_yusP [GEPR] COG0477 Permeases of the major facilitator superf... 226 1e-58 DR0258 [GEPR] COG0477 Permeases of the major facilitator superfa... 223 7e-58 mlr6842 [GEPR] COG0477 Permeases of the major facilitator superf... 214 3e-55 >RSp0663 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 537 Score = 655 bits (1691), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/528 (63%), Positives = 427/528 (80%) Query: 1 MSPYKEAAHSSGQVLPFRESLMATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAW 60 M+ + HS QVLPF+ESL+A LGICFV++LVALDQT+VGTALPT+VAELKGFDLYAW Sbjct: 8 MALHTALPHSHTQVLPFKESLLAMLGICFVVVLVALDQTVVGTALPTVVAELKGFDLYAW 67 Query: 61 VATSYLLTSVITVPIFGRLGDYFGRKPFLIASIIIFVIASMLCGMADSMLFLVLARGLQG 120 VATSYLLTSV+TVP+FGRLGD++GRKPF++ASI++F +AS++CGMA SM FLV AR LQG Sbjct: 68 VATSYLLTSVVTVPVFGRLGDFYGRKPFVVASIVVFTLASVMCGMAGSMAFLVWARALQG 127 Query: 121 IGGGMLVGTAFASAADLFPDPHIRLRWQIILSAAYGIATSVGPSLGGFLTQSLGWRWTFY 180 IGGGMLVGTA+A ADLFPD +RLRWQ++LSA++GIA ++GP+LGG++TQ+LGWR FY Sbjct: 128 IGGGMLVGTAYACIADLFPDARVRLRWQVLLSASFGIANAIGPTLGGWMTQALGWRSVFY 187 Query: 181 VNLPVGLVSLFFAMRYIPHIRHHKNAGKVRLDWLGALLISVALGSLQLLVELFPKRGLTG 240 VN+P G++ L+FA R++PH+R +AG++R DW GALLI+ ALG+LQL VE P+ GL+ Sbjct: 188 VNVPFGVLGLWFAWRFLPHLRQSLHAGRIRPDWQGALLITAALGALQLSVEWLPRHGLSL 247 Query: 241 GMLALLVVAIGAFYALWKWERQVEQPILPFEMFKDPALSSLFLLSVLAGFSMFSMLMYAP 300 +L LV++ AF LW WE++ EQP+LPFEM +DPAL++LF+L+ L+GFSMF++L YAP Sbjct: 248 PVLGWLVLSAAAFAGLWWWEQRAEQPLLPFEMVRDPALATLFVLAALSGFSMFALLFYAP 307 Query: 301 LLFQGGFGMSPREAGLLITPLVACITVASIVNGRIVTRIPNPNMMMYVGFVLIALSCLGI 360 LLFQGGFGMSP++AGL+ITPLV CIT+ SI+NGR+VTRIP P +M+Y GF L+AL+ G+ Sbjct: 308 LLFQGGFGMSPQQAGLVITPLVVCITLGSIINGRLVTRIPRPTVMLYAGFALLALALAGM 367 Query: 361 VLSQRNTPTGFMLATMLAGGFGLGLVLPNLTVFAQQAASREHLGIATALLQSLRMIGGML 420 S R TP + ML G GLG VLPNLTVFAQQ+A R HLGIATALLQSLRM+GGM+ Sbjct: 368 AASSRATPQLALTLLMLLAGLGLGFVLPNLTVFAQQSAGRAHLGIATALLQSLRMVGGMI 427 Query: 421 GTAVTGTLVTQMYGSGVERALESDHAAQWLAEFKDPEILVNHDIQSTLLAQMLQAGHNGS 480 GTA+ GTLV++ Y +GV AL +D A QWL DPEIL++H+ Q+ LLAQM AGH+G+ Sbjct: 428 GTALVGTLVSERYAAGVGDALRADGATQWLRRLADPEILIDHEAQTALLAQMQSAGHDGA 487 Query: 481 ALLDAARDALVGAIHMGIALAVVSALIGLWMVRRVPLIRFTPNEKVET 528 ALL AAR LV AIH+G+ +A V A++GLW VRRVP + E V+T Sbjct: 488 ALLGAARHVLVSAIHLGLIVAAVVAVVGLWRVRRVPPVALYHVEPVQT 535 >DRA0061 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 643 Score = 228 bits (580), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 156/443 (35%), Positives = 235/443 (53%), Gaps = 23/443 (5%) Query: 3 PYKEAAH--SSGQVLPFRESLMATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAW 60 P + AH + ++L R G+ + L ALDQTIV ALP IV+EL G +LY+W Sbjct: 9 PAADPAHYINYAELLDLRTKKFIVFGVLLALFLSALDQTIVSAALPRIVSELNGLNLYSW 68 Query: 61 VATSYLLTSVITVPIFGRLGDYFGRKPFLIASIIIFVIASMLCGMA----------DSML 110 V T+YLL+S VPI+G+L D +GRKP L+ I++F+I S LCG++ M+ Sbjct: 69 VTTAYLLSSAALVPIYGKLSDLYGRKPVLVFGIVVFLIGSALCGLSGEPFLGNLFGSPMM 128 Query: 111 FLVLARGLQGIGGGMLVGTAFASAADLFPDPHIRLRWQIILSAAYGIATSVGPSLGGFLT 170 LV+ RGLQGIG L AFA ADLF +P R ++Q + A +G+++ VGP LGGFLT Sbjct: 129 QLVVFRGLQGIGAAALATVAFAIVADLF-EPRERAKYQGLFGAVFGLSSVVGPLLGGFLT 187 Query: 171 QSLGWRWTFYVNLPVGLVSLFFAMRYIPHIRHHKNAGKVRLDWLGALLISVALGSLQLLV 230 L WRW FYVN+P+GLV+L +P + + + +D+LGA+LI + ++ LL+ Sbjct: 188 DQLSWRWVFYVNVPIGLVALAVIFARMPRL---ASGLRGSVDYLGAVLIVIF--TVPLLL 242 Query: 231 ELFPKRGLTGG-----MLALLVVAIGAFYALWKWERQVEQPILPFEMFKDPALSSLFLLS 285 L T G ML L ++ A A WER+ E PI+P +F DP ++ Sbjct: 243 ALTWGADGTAGWTDAKMLGLFGTSLAALLAFIFWERRHESPIVPLTLFADPTIAWTMTSR 302 Query: 286 VLAGFSMFSMLMYAPLLFQGGFGMSPREAGLLITPLVACITVASIVNGRIVTRIPNPNMM 345 L G +++ L G S AGL PL + + +G + R + + Sbjct: 303 FLLGAGFLGAVLFLTLYLVNVAGFSATGAGLATLPLTLGFVIGAQGSGLLAARSGHYKSL 362 Query: 346 MYVGFVLIALSCLGIVLSQRNTPTGFMLATMLAGGFGLGLVLPNLTVFAQQAASREHLGI 405 + +V+ L+ + Q +TP G + A M G GLG + T+ AQ A + +G+ Sbjct: 363 LVGAYVVAVLAFWWLSTVQVDTPYGLLAARMFLVGLGLGPSVSLFTLAAQNAVAPYQIGV 422 Query: 406 ATALLQSLRMIGGMLGTAVTGTL 428 T++ + +GG +G A+ G + Sbjct: 423 VTSVGTFFQQLGGTIGIALFGAI 445 >BS_yusP [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 541 Score = 226 bits (576), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 152/446 (34%), Positives = 242/446 (54%), Gaps = 33/446 (7%) Query: 1 MSPYKEAAHSSGQVLPFRESLMATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAW 60 M KE S + +L+ T G+ + ALD TIVGTA+P IV +L G + W Sbjct: 1 MKMSKEGKQS-------KRTLLIT-GLIIAMFFSALDGTIVGTAMPKIVGDLGGLSMMTW 52 Query: 61 VATSYLLTSVITVPIFGRLGDYFGRKPFLIASIIIFVIASMLCGMADSMLFLVLARGLQG 120 + T+YLLTS VPI G+L D GR+ ++ +IIF+ AS LCGMA++M L++ RGLQG Sbjct: 53 LTTAYLLTSTTIVPIAGKLADLLGRRIVYVSGLIIFMAASALCGMANNMTELIIFRGLQG 112 Query: 121 IGGGMLVGTAFASAADLFPDPHIRLRWQIILSAAYGIATSVGPSLGGFLTQSLGWRWTFY 180 IGGG+++ A DLF R ++Q + A YG+A+ +GP +GG++ SL W+W FY Sbjct: 113 IGGGIMMPMAMIVIGDLFTGKQ-RAKFQGVFGAIYGLASVIGPQIGGWIVDSLNWKWVFY 171 Query: 181 VNLPVGLVSLFFAMRYIPHIRHHKNAGKVRLDWLGALLISVALGSLQLLVELFPKRGLTG 240 +NLPVG++++ F R ++ + G + D G + V + SL L + K Sbjct: 172 INLPVGIIAVIFIAR---GLQGRQQTGPINFDIAGIFTMIVGVVSLLLALSFGGKDYAWD 228 Query: 241 -----GMLALLVVAIGAFYALWKWERQVEQPILPFEMFKDPALSSLFLLSVLAGFSMFSM 295 G+ AL ++ I +F + E + ++PILP +FK+ + L L+ MF Sbjct: 229 SWQILGLFALALIGIVSFIIV---ESKAKEPILPMYLFKNRTFTFLNLIGFFMSIGMFGA 285 Query: 296 LMYAPLLFQGGFGMSPREAGLLITPLVACITVASIVNGRIVTRIP-NPN-----MMMYVG 349 + + P QG G+S E+G ++TP++ + + SI+ G++V +I P ++M G Sbjct: 286 ITFVPFFMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQIITGMLVMAGG 345 Query: 350 FVLIALSCLGIVLSQRNTPTGFMLATMLAGGFGLGLVLPNLTVFAQQAASREHLGIATAL 409 F+L+ + + + T FM G G+GLV+P LT+ Q++ S+E LG+ T+ Sbjct: 346 FLLLTTLD---LDTSKLVATSFMAII----GLGMGLVMPILTLALQESFSKEELGVVTSS 398 Query: 410 LQSLRMIGGMLGTAVTGTLVTQMYGS 435 Q R IGG G + G ++ G+ Sbjct: 399 SQFFRSIGGTFGITMLGAVMNARSGN 424 >DR0258 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 544 Score = 223 bits (569), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 178/527 (33%), Positives = 272/527 (51%), Gaps = 50/527 (9%) Query: 13 QVLPFRESLMATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWVATSYLLTSVIT 72 L RE L+A GI V+ L +L+ T+VG+A+P ++++L GF LYAW T+Y LT+ +T Sbjct: 13 NTLSEREKLLAFAGILTVLFLSSLNMTVVGSAMPRVISDLGGFHLYAWAFTAYSLTTTVT 72 Query: 73 VPIFGRLGDYFGRKPFLIASIIIFVIASMLCGMADSMLFLVLARGLQGIGGGMLVGTAFA 132 +PI G L D +GR+P ++ I++F + SM G SM L+ R +QGIGGG L+ +F Sbjct: 73 IPIVGTLSDRYGRRPLILLGIVVFALGSMGLGFVQSMEQLIALRAIQGIGGGTLMAMSFT 132 Query: 133 SAADLFPDPHIRLRWQIILSAAYGIATSVGPSLGGFLTQSLGWRWTFYVNLPVGLVSLFF 192 + ADLF P R R+Q A +GI++ VGP +GGFLT GWR F++NLP L++LFF Sbjct: 133 AIADLF-TPIERGRYQGYTGAVWGISSVVGPLVGGFLTDHFGWRSVFFLNLPFALLALFF 191 Query: 193 AMRYIPHIRHHKNAGKVRLDWLGALLISVALGSLQLLVELFPKRGLTGGMLA-------- 244 R+ + K D LGA L++ A+ +L L V GG A Sbjct: 192 IWRFFRLPAPTPGSVKGGFDALGATLLAGAVTTLTLAVS------WGGGTYAWDSPRILG 245 Query: 245 --LLVVAIGAFYALWKWERQVEQPILPFEMFKDPALSSLFLLSVLAGF----SMFSMLMY 298 +A+GA+YA RQ E+ IL + +D + LL+ LAGF M++ ++Y Sbjct: 246 LLGATLALGAWYAAHS-ARQ-ERAILDLGLLRDRGI----LLASLAGFLVSAGMYAAILY 299 Query: 299 APLLFQGGFGMSPREAGLLITPLVACITVASIVNGRIVTRIPNPNMMMYVGFVLIALSCL 358 PL QG G S +GL + PL+ + + S ++G++V+R ++ G ++ +L+ + Sbjct: 300 LPLYMQGVRGSSASGSGLALAPLMGGMILTSTLSGQLVSRTGRYKRLIVGGALVASLALV 359 Query: 359 GIVLSQRNTPTGFMLATMLAGGFGLGLVLPNLTVFAQQAASREHLGIATALLQSLRMIGG 418 +TP + M+ G GLG V LT+ Q AA R+ LG AT Q R IG Sbjct: 360 LSSTLSLSTPLWLAVTMMILLGLGLGPVNSQLTLAVQNAAPRQKLGSATGGNQFFRQIG- 418 Query: 419 MLGTAVTGTLVTQMYGSGVERALESDHAAQWLAEFK-----------DPEILVNHDIQST 467 GTL ++G+ V L D +A+ A + +P +L + Sbjct: 419 -------GTLAVSLFGALVNAHLSHDLSAKLPAAVRRLPAPMQDAIANPNLLTSERATHL 471 Query: 468 LLAQMLQAGHNG--SALLDAARDALVGAIHMGIALAVVSALIGLWMV 512 L + + GH+ + ++ A R +VGAI V + L+GL V Sbjct: 472 LGWALKKMGHHEMLAPIMQALRGVMVGAIDQ--VFLVSAGLVGLAFV 516 >mlr6842 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 529 Score = 214 bits (546), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 152/435 (34%), Positives = 223/435 (51%), Gaps = 15/435 (3%) Query: 2 SPYKEAAHSSGQVLPFRESLMATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWV 61 S +A + P +L+ G + + +D IV TALPTI EL L+ WV Sbjct: 25 STLPDAPPAESGAKPDITTLVVYSGALIAMFMATIDMQIVVTALPTIAGELGNLHLFGWV 84 Query: 62 ATSYLLTSVITVPIFGRLGDYFGRKPFLIASIIIFVIASMLCGMADSMLFLVLARGLQGI 121 +YLL++ P +G+LGD +GRK ++ +I +F++ S++CGMA SM L+ AR LQGI Sbjct: 85 GAAYLLSTAAVAPFYGKLGDMYGRKNVVLTAIALFLLGSLVCGMAWSMESLIAARVLQGI 144 Query: 122 GGGMLVGTAFASAADLFPDPHIRLRWQIILSAAYGIATSVGPSLGGFLTQSLGWRWTFYV 181 GGG L+ +AFA +LF P R ++Q SA + +++ +GP GG++T GWRW F V Sbjct: 145 GGGGLMVSAFAMIGELF-GPRDRAKYQGYSSAVFALSSVLGPLAGGYITSLFGWRWVFLV 203 Query: 182 NLPVGLVS---LFFAMRYIPHIRHHKNAGKVRLDWLGALLISVALGSLQLL---VELFPK 235 NLP+G+V L FAMR + + H +D+LG LL+ A+G+ ++ L Sbjct: 204 NLPIGIVVLAILAFAMRSRFNEKRHS------IDYLGGLLL--AIGTTAIVYWGYHLLDP 255 Query: 236 RGLTGGMLALLVVAIGAFYALWKWERQVEQPILPFEMFKDPALSSLFLLSVLAGFSMFSM 295 G AL VVA+ A + ER+ E+PI+P +F + + +SV+AG M Sbjct: 256 AGPDLLTFALPVVALAAIASFILVERRAEEPIVPLRLFGSSTVRIVSGVSVVAGSVTLGM 315 Query: 296 LMYAPLLFQGGFGMSPREAGLLITPLVACITVASIVNGRIVTRIPNPNMMMYVGFVLIAL 355 Y L Q G+SP E G L P V SIV GR++ M V + L Sbjct: 316 FFYFALYMQTLTGLSPAEVGFLFLPASLTSMVISIVAGRVIAATGRYKWMPVVAMGIGGL 375 Query: 356 SCLGIVLSQRNTPTGFMLATMLAGGFGLGLVLPNLTVFAQQAASREHLGIATALLQSLRM 415 +G V +TP + M G +GL L V Q AA + +G T+L+ R Sbjct: 376 LMIGFVFINSHTPIWVLAVMMGLFGISMGLQFQVLIVAIQAAAPLQDIGAVTSLITQART 435 Query: 416 IGGMLGTAVTGTLVT 430 IG LG A+ G ++T Sbjct: 436 IGASLGLALNGAVMT 450