BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0004.p (193 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstoni... 221 9e-58 YPO4074 [L] COG2818 3-methyladenine DNA glycosylase Ype Yersinia... 202 3e-52 lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria... 197 2e-50 SP0180 [L] COG2818 3-methyladenine DNA glycosylase Spn Streptoco... 194 8e-50 STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonel... 192 4e-49 >RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstonia solanacearum Length = 190 Score = 221 bits (562), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 100/191 (52%), Positives = 129/191 (67%), Gaps = 1/191 (0%) Query: 3 VQRCAWVNLANPRYVTYHDEEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRETYRAA 62 + RC WV +P + YHD EWG P HD+ L+EML LEGAQAGLSW+T+L KR Y+ Sbjct: 1 MSRCCWVG-EDPLMIAYHDTEWGTPSHDDRHLYEMLVLEGAQAGLSWQTILRKRARYQEV 59 Query: 63 FDQWNPEKIARYTDAKVAKLLADPGIVRNRLKVAATITNAQSYLRLRDEVGGLDPFLWAY 122 FD ++P ++AR+T A++ LLADPGIVRNR KV A + NA+ L ++D VG LD FLWA+ Sbjct: 60 FDGFDPARVARFTPARIETLLADPGIVRNRAKVEAAVVNARKVLEVQDAVGSLDGFLWAF 119 Query: 123 VDGKPIRNKWKDLSDAPAKTALSDQVSKDLLKRGFKFVGSTIIYAYLQGIGIIDDHVVDC 182 V G+P+ N+W DAPA T S +SK L RGFKFVG TI YA++Q G++DDH C Sbjct: 120 VGGRPVVNRWSSYRDAPASTEASKAMSKALAARGFKFVGPTICYAFMQATGMVDDHEAGC 179 Query: 183 HCHGRKHKQPK 193 G+ PK Sbjct: 180 FLAGKAKAGPK 190 >YPO4074 [L] COG2818 3-methyladenine DNA glycosylase Ype Yersinia pestis Length = 190 Score = 202 bits (515), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 95/185 (51%), Positives = 128/185 (69%), Gaps = 1/185 (0%) Query: 1 MSVQRCAWVNLANPRYVTYHDEEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRETYR 60 MS+QRC WV ++P Y+ YHD EWGVP D LFEM+ LEG QAGLSW TVL KRE YR Sbjct: 1 MSLQRCGWVT-SDPLYLAYHDTEWGVPLKDSRALFEMICLEGQQAGLSWITVLKKREHYR 59 Query: 61 AAFDQWNPEKIARYTDAKVAKLLADPGIVRNRLKVAATITNAQSYLRLRDEVGGLDPFLW 120 +F ++P K+A+ +V + D GI+R+R K+ A ITNAQ+YL + F+W Sbjct: 60 KSFHHFDPVKVAKMGPEEVEIRVQDSGIIRHRGKIQAIITNAQAYLAMEANGEDFSRFIW 119 Query: 121 AYVDGKPIRNKWKDLSDAPAKTALSDQVSKDLLKRGFKFVGSTIIYAYLQGIGIIDDHVV 180 ++VD +P N W L++APA TA+SD +SK L KRGFKF+GSTI YA++Q G+++DH+ Sbjct: 120 SFVDDEPKINHWWCLAEAPATTAVSDAMSKALKKRGFKFIGSTICYAFMQASGLVNDHMA 179 Query: 181 DCHCH 185 +C CH Sbjct: 180 NCFCH 184 >lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria innocua Length = 193 Score = 197 bits (500), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 91/181 (50%), Positives = 131/181 (72%), Gaps = 1/181 (0%) Query: 5 RCAWVNLANPRYVTYHDEEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRETYRAAFD 64 RC W ++ +P + YHD EW VP D+T LFEMLNLEGAQAGLSW+ +L+KR+ Y+ AF Sbjct: 6 RCPW-SINDPFELAYHDGEWCVPSKDDTYLFEMLNLEGAQAGLSWKLILHKRKAYQEAFF 64 Query: 65 QWNPEKIARYTDAKVAKLLADPGIVRNRLKVAATITNAQSYLRLRDEVGGLDPFLWAYVD 124 ++ +K AR TD +A+++++ IV+NRLKV A TNA + +++ E G ++W++ + Sbjct: 65 HFDIDKCARLTDEDLARIVSEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIWSFTN 124 Query: 125 GKPIRNKWKDLSDAPAKTALSDQVSKDLLKRGFKFVGSTIIYAYLQGIGIIDDHVVDCHC 184 G+ I N+W+ + + PAKT LS+++SKDL KRGFKFVG IIY+YLQ IGI+DDH+ C Sbjct: 125 GERIINEWQGMGEVPAKTELSEKISKDLKKRGFKFVGPVIIYSYLQAIGILDDHLRSCPF 184 Query: 185 H 185 H Sbjct: 185 H 185 >SP0180 [L] COG2818 3-methyladenine DNA glycosylase Spn Streptococcus pneumoniae TIGR4 Length = 178 Score = 194 bits (494), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 87/178 (48%), Positives = 120/178 (67%) Query: 11 LANPRYVTYHDEEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRETYRAAFDQWNPEK 70 + NP Y+ YHDEEWG P HD+ LFE+L +E QAGLSWETVLNKR+ +R F + Sbjct: 1 MTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQAGLSWETVLNKRQAFREVFHSYQIHS 60 Query: 71 IARYTDAKVAKLLADPGIVRNRLKVAATITNAQSYLRLRDEVGGLDPFLWAYVDGKPIRN 130 +A TD ++ +L +P I+RNR K+ AT NAQ++L+L+ E G D +LW++V+GK + N Sbjct: 61 VAEMTDTELEAMLENPAIIRNRAKLFATRANAQAFLQLQAEYGSFDAYLWSFVEGKTVVN 120 Query: 131 KWKDLSDAPAKTALSDQVSKDLLKRGFKFVGSTIIYAYLQGIGIIDDHVVDCHCHGRK 188 D APAKT LS++++KDL KRGFKF G + ++LQ G++DDH DC G K Sbjct: 121 DVPDYRQAPAKTPLSEKLAKDLKKRGFKFTGPVAVLSFLQAAGLVDDHENDCEWKGLK 178 >STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonella typhimurium LT2 Length = 193 Score = 192 bits (487), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 90/188 (47%), Positives = 125/188 (66%), Gaps = 2/188 (1%) Query: 3 VQRCAWVNLANPRYVTYHDEEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRETYRAA 62 +QRC WV+ +P Y+ YHD EWGVP D +LFEM+ LEG QAGLSW TVL KRE YRA Sbjct: 1 MQRCDWVS-QDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRAC 59 Query: 63 FDQWNPEKIARYTDAKVAKLLADPGIVRNRLKVAATITNAQSYLRLRDEVGGLDPFLWAY 122 F Q++P +IA + V LL + GI+R+R K+ A I+NA+++L + F+W++ Sbjct: 60 FHQFDPVRIAAMQEEDVEHLLQNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSF 119 Query: 123 VDGKPIRNKWKDLSDAPAKTALSDQVSKDLLKRGFKFVGSTIIYAYLQGIGIIDDHVVDC 182 VDG+P + L + P T SD ++K L KRGFKFVG+TI Y+++Q G+++DH+ C Sbjct: 120 VDGQPQITQAASLDEIPTSTPASDALAKALKKRGFKFVGTTICYSFMQACGLVNDHITGC 179 Query: 183 HCH-GRKH 189 CH G KH Sbjct: 180 FCHPGEKH 187