BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0028.p (254 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso R... 318 9e-87 AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu A... 246 3e-65 NMA0927 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) NmA N... 241 1e-63 NMB0718 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Nme N... 238 1e-62 VC0987 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Vch Vi... 234 9e-62 >RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso Ralstonia solanacearum Length = 371 Score = 318 bits (814), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 145/230 (63%), Positives = 177/230 (76%), Gaps = 5/230 (2%) Query: 1 MRYGSPAVSDVLDELKAQGCDRILVLPAYPQYSGTTTASIFDAVFQHFAKVRNVPELRLI 60 MRYG+P++ V+ L+ QG +RILVLP YPQYSGTTTA+ FD VF+ ++RN PELRL+ Sbjct: 119 MRYGNPSIPSVMQTLRKQGVERILVLPMYPQYSGTTTATAFDEVFRVMGQMRNQPELRLV 178 Query: 61 KHYHDHDGYIQALKRSVQTHWDANGQPD-----KLVMSFHGVPKRTLLLGDPYHCECYKT 115 KH+HDH YI AL + V +W +G PD KL++SFHGVP+RTL LGDPYHC C KT Sbjct: 179 KHFHDHPAYINALHQQVGAYWAQHGAPDFARGDKLLLSFHGVPRRTLELGDPYHCACLKT 238 Query: 116 ARLLAEALGLSEAEYVVTFQSRFGKAEWLQPYTAPTLQELARQGVQRVDVMCPGFTSDCL 175 RLL EALGL +Y+VTFQSRFG+AEWLQPYTAPTL+EL R G RVDV CPGF +DCL Sbjct: 239 GRLLGEALGLQPGQYLVTFQSRFGRAEWLQPYTAPTLEELGRVGTGRVDVFCPGFPADCL 298 Query: 176 ETLEEIAMEAKAEFLHAGGREFHFIPCLNDAPAWGQGMMEIAEQHLIGWP 225 ETLEEIAME ++ F AGG++FH+IPCLND+ W G+ +IA+ HL GWP Sbjct: 299 ETLEEIAMEGQSTFRVAGGKDFHYIPCLNDSEPWIAGLADIAQAHLQGWP 348 >AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 368 Score = 246 bits (629), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 113/225 (50%), Positives = 154/225 (68%), Gaps = 1/225 (0%) Query: 1 MRYGSPAVSDVLDELKAQGCDRILVLPAYPQYSGTTTASIFDAVFQHFAKVRNVPELRLI 60 MRYG P+++ +D LK QGC++IL+ P YPQY+ +TTA++ D F+H K+R P +R + Sbjct: 143 MRYGQPSIASRIDALKEQGCEKILLFPLYPQYAASTTATVNDKAFEHLMKLRWQPAIRTV 202 Query: 61 KHYHDHDGYIQALKRSVQTHWDA-NGQPDKLVMSFHGVPKRTLLLGDPYHCECYKTARLL 119 YHD YI+ L SV+ H + +P+ L+ SFHG+P+ GDPY+C C KTARLL Sbjct: 203 PPYHDDPAYIEGLAASVKNHLATLDWEPEMLITSFHGIPQSYFKKGDPYYCHCQKTARLL 262 Query: 120 AEALGLSEAEYVVTFQSRFGKAEWLQPYTAPTLQELARQGVQRVDVMCPGFTSDCLETLE 179 EALG +E +++TFQSRFG EWLQPYT T+++LA +G++R+ VM PGF SDCLETLE Sbjct: 263 REALGRTEKNFMITFQSRFGPEEWLQPYTDKTVEKLASEGIKRIAVMNPGFVSDCLETLE 322 Query: 180 EIAMEAKAEFLHAGGREFHFIPCLNDAPAWGQGMMEIAEQHLIGW 224 EIA EA FLH GG +F IPCLND+ + ++ + L GW Sbjct: 323 EIAGEAGEIFLHNGGEKFTHIPCLNDSTEGMNVLEKVVRRELQGW 367 >NMA0927 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) NmA Neisseria meningitidis Z2491 Length = 336 Score = 241 bits (614), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 108/224 (48%), Positives = 156/224 (69%) Query: 1 MRYGSPAVSDVLDELKAQGCDRILVLPAYPQYSGTTTASIFDAVFQHFAKVRNVPELRLI 60 M YG+P+V+DVL ELKAQG R+LV+P YPQY+ +++ + D V + RN +R + Sbjct: 112 MTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTV 171 Query: 61 KHYHDHDGYIQALKRSVQTHWDANGQPDKLVMSFHGVPKRTLLLGDPYHCECYKTARLLA 120 ++D GYI A+K + +W +G+ KL++SFHGVP++ LGDPY EC TA+LLA Sbjct: 172 SRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHYDLGDPYPDECRHTAKLLA 231 Query: 121 EALGLSEAEYVVTFQSRFGKAEWLQPYTAPTLQELARQGVQRVDVMCPGFTSDCLETLEE 180 EAL L+E +YVV+FQS+FG+A+W+ P T +L +QGV +DV CPGF +DCLET+EE Sbjct: 232 EALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEE 291 Query: 181 IAMEAKAEFLHAGGREFHFIPCLNDAPAWGQGMMEIAEQHLIGW 224 IA+ + +F AGG+ + +IPCLND P W ++ +AE++L GW Sbjct: 292 IALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGGW 335 >NMB0718 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Nme Neisseria meningitidis MC58 Length = 360 Score = 238 bits (606), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 107/224 (47%), Positives = 155/224 (69%) Query: 1 MRYGSPAVSDVLDELKAQGCDRILVLPAYPQYSGTTTASIFDAVFQHFAKVRNVPELRLI 60 M YG+P+V+DVL ELKAQG R+LV+P YPQY+ +++ + D V + RN +R + Sbjct: 136 MTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTV 195 Query: 61 KHYHDHDGYIQALKRSVQTHWDANGQPDKLVMSFHGVPKRTLLLGDPYHCECYKTARLLA 120 ++D GYI A+K + +W +G+ KL++SFHGVP++ LGDPY EC TA+LLA Sbjct: 196 SRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHHDLGDPYPDECRHTAKLLA 255 Query: 121 EALGLSEAEYVVTFQSRFGKAEWLQPYTAPTLQELARQGVQRVDVMCPGFTSDCLETLEE 180 EAL L+E +YVV+FQS+FG+A+W+ P T +L +QGV +DV CPGF +DCLET+EE Sbjct: 256 EALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEE 315 Query: 181 IAMEAKAEFLHAGGREFHFIPCLNDAPAWGQGMMEIAEQHLIGW 224 IA+ + +F AGG+ + +IPCLND P W ++ +AE++L W Sbjct: 316 IALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGSW 359 >VC0987 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Vch Vibrio cholerae Length = 324 Score = 234 bits (598), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 107/206 (51%), Positives = 150/206 (72%) Query: 1 MRYGSPAVSDVLDELKAQGCDRILVLPAYPQYSGTTTASIFDAVFQHFAKVRNVPELRLI 60 M YG P++ + + +L+ QG ++I+VLP YPQYS TTTA++FD + + ++ VPEL I Sbjct: 104 MTYGEPSLLEGVRKLQQQGVEQIVVLPLYPQYSATTTAAVFDGLAKALRQLPVVPELHFI 163 Query: 61 KHYHDHDGYIQALKRSVQTHWDANGQPDKLVMSFHGVPKRTLLLGDPYHCECYKTARLLA 120 + YHDH YIQAL +SV+ W +GQ D L+ S+HG+PKR GD Y C KT LLA Sbjct: 164 RDYHDHPLYIQALAKSVRASWQQHGQGDLLLCSYHGIPKRYAQNGDIYPEHCLKTTELLA 223 Query: 121 EALGLSEAEYVVTFQSRFGKAEWLQPYTAPTLQELARQGVQRVDVMCPGFTSDCLETLEE 180 +ALGL + + ++T+QS+FGK EWLQPYT T++ L RQG++++DV+CP F+ DCLETLEE Sbjct: 224 QALGLPQDKVMMTYQSQFGKEEWLQPYTDKTMEALPRQGIKKLDVICPAFSVDCLETLEE 283 Query: 181 IAMEAKAEFLHAGGREFHFIPCLNDA 206 IA + + FLH+GG FH++PCLND+ Sbjct: 284 IAEQNQEIFLHSGGEAFHYVPCLNDS 309