BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0003.p (239 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2741 [E] COG0014 Gamma-glutamyl phosphate reductase Rso Ralst... 338 6e-93 PA4007 [E] COG0014 Gamma-glutamyl phosphate reductase Pae Pseudo... 338 6e-93 aq_1071 [E] COG0014 Gamma-glutamyl phosphate reductase Aae Aquif... 245 6e-65 BMEI0208 [E] COG0014 Gamma-glutamyl phosphate reductase Bme Bruc... 241 9e-64 MA4100 [E] COG0014 Gamma-glutamyl phosphate reductase Mac Methan... 237 2e-62 >RSc2741 [E] COG0014 Gamma-glutamyl phosphate reductase Rso Ralstonia solanacearum Length = 426 Score = 338 bits (867), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 169/239 (70%), Positives = 193/239 (80%), Gaps = 6/239 (2%) Query: 2 AVGALITMTEYVDVIVPRGGKGLIERLIKESKVPMIKHLDGICHVYIDDKAELQKALDVA 61 AVG LITMTEYVDVIVPRGGK LI RL++E++VPMIKHLDGICHVYID A++ KA+ + Sbjct: 191 AVGKLITMTEYVDVIVPRGGKSLIARLMEEARVPMIKHLDGICHVYIDVDADIDKAVRIC 250 Query: 62 FNAKCHRYGTCNTMETLLVARAVAAEVLPKLAELYRAKDVELRGDAESRRIL--AGYPLL 119 NAK RY CNTMETLLVAR VAA L LA +Y+ K VELR ++R L AG+ L Sbjct: 251 DNAKTQRYAPCNTMETLLVAREVAARALTPLARIYQDKGVELRVCPDTRATLEAAGFSGL 310 Query: 120 KEAVEEDWSTEYLAPILSVKIVAGMDEAIDHINTYSSQHTDAIVTEDYTRAMRFLREVDS 179 K+A E DW TEYLAPILS++ V G+D AI+HINTY S HTD+IVTE+Y+ MRFLREVDS Sbjct: 311 KDATEADWHTEYLAPILSIRTVDGVDAAIEHINTYGSAHTDSIVTENYSTGMRFLREVDS 370 Query: 180 ASVMVNASTRFADGFEYGLGFFHGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQVR 238 ASVM+NASTRFADGFEYGL GAEIGISNDKLHARGPVGLEGLTSLKYVV G G++R Sbjct: 371 ASVMINASTRFADGFEYGL----GAEIGISNDKLHARGPVGLEGLTSLKYVVFGHGEIR 425 >PA4007 [E] COG0014 Gamma-glutamyl phosphate reductase Pae Pseudomonas aeruginosa Length = 421 Score = 338 bits (867), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 172/237 (72%), Positives = 191/237 (80%), Gaps = 6/237 (2%) Query: 2 AVGALITMTEYVDVIVPRGGKGLIERLIKESKVPMIKHLDGICHVYIDDKAELQKALDVA 61 AVGALI+M EYVDVIVPRGGKGLIER+ +E+KVP+IKHLDGICHVYID A+L KA+ VA Sbjct: 190 AVGALISMPEYVDVIVPRGGKGLIERISREAKVPVIKHLDGICHVYIDVAADLDKAIRVA 249 Query: 62 FNAKCHRYGTCNTMETLLVARAVAAEVLPKLAELYRAKDVELRGDAESRRILAGYPLLKE 121 NAK RY CNTMETLLV +A VLP LA +YR K VELRGDA +R +L L E Sbjct: 250 DNAKTQRYAPCNTMETLLVHAGIAERVLPPLATIYREKGVELRGDAATRALLGADVL--E 307 Query: 122 AVEEDWSTEYLAPILSVKIVAGMDEAIDHINTYSSQHTDAIVTEDYTRAMRFLREVDSAS 181 A EEDW TEY APILS++IV G+D AI+HINTY SQHTDAI+TE+++ A RFL EVDSAS Sbjct: 308 ATEEDWRTEYNAPILSIRIVDGLDAAIEHINTYGSQHTDAIITENFSDARRFLAEVDSAS 367 Query: 182 VMVNASTRFADGFEYGLGFFHGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQVR 238 VMVNASTRFADGFEYGL GAEIGIS DKLHARGPVGLEGLTS KYVV G G VR Sbjct: 368 VMVNASTRFADGFEYGL----GAEIGISTDKLHARGPVGLEGLTSEKYVVFGDGHVR 420 >aq_1071 [E] COG0014 Gamma-glutamyl phosphate reductase Aae Aquifex aeolicus Length = 443 Score = 245 bits (626), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 122/241 (50%), Positives = 168/241 (69%), Gaps = 9/241 (3%) Query: 3 VGALITMTEYVDVIVPRGGKGLIERLIKESKVPMIKHLDGICHVYIDDKAELQKALDVAF 62 V ++ M +DV +PRGG+ LI +++ +KVP+IKH G+C++Y+DD+A+L+KA + + Sbjct: 194 VWEILKMEGKIDVAIPRGGESLIRAVVEHAKVPVIKHYKGVCNIYVDDEADLEKAYHIVY 253 Query: 63 NAKCHRYGTCNTMETLLVARAVAAEVLPKLAELYRAKDVELRGDAESRRILAGYPLL--- 119 NAK R CN +E L++ R + E PK+A VELR D ES +++ P L Sbjct: 254 NAKVQRPSVCNAVENLVINRKILKEFFPKMAYYLGKAGVELRCDEESLQVIKENPKLSFV 313 Query: 120 --KEAVEEDWSTEYLAPILSVKIVAGMDEAIDHINTYSSQHTDAIVTEDYTRAMRFLREV 177 K A EED+ E+L IL+VK+V +DEAI I Y S+H+DAI+TE+YT+AM+FLREV Sbjct: 314 NAKPATEEDYYEEFLDLILAVKVVDDVDEAIAFIEKYGSKHSDAIITENYTKAMKFLREV 373 Query: 178 DSASVMVNASTRFADGFEYGLGFFHGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQV 237 DSA+V VNASTRF DG E+GL GAE+GIS DK+HARGP+ LE LT K+V+LG+GQV Sbjct: 374 DSAAVYVNASTRFTDGNEFGL----GAEMGISTDKIHARGPMALEELTIPKFVILGEGQV 429 Query: 238 R 238 R Sbjct: 430 R 430 >BMEI0208 [E] COG0014 Gamma-glutamyl phosphate reductase Bme Brucella melitensis Length = 426 Score = 241 bits (616), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 129/227 (56%), Positives = 157/227 (69%), Gaps = 9/227 (3%) Query: 13 VDVIVPRGGKGLIERLIKESKVPMIKHLDGICHVYIDDKAELQKALDVAFNAKCHRYGTC 72 +DVIVPRGGK L+ R+ E++VP+ HL+GICH+YID A+L A +A +AK R G C Sbjct: 207 IDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGIC 266 Query: 73 NTMETLLVARAVAAEVL-PKLAELYRAKDVELRGDAESRRILAGYPLLKEAVEEDWSTEY 131 ETLLV RAVA+ L P L +L A E+RG AE +LA YP K A EEDWSTEY Sbjct: 267 GAAETLLVDRAVASTHLAPILGDLA-AGGCEIRGSAE---VLALYPAAKPATEEDWSTEY 322 Query: 132 LAPILSVKIVAGMDEAIDHINTYSSQHTDAIVTEDYTRAMRFLREVDSASVMVNASTRFA 191 L I+SV +V G+ AIDHIN YSS HT+AIV ED RF E+DSA ++ NAST+FA Sbjct: 323 LDAIISVALVDGISGAIDHINRYSSHHTEAIVAEDAQTVARFFNEIDSAILLHNASTQFA 382 Query: 192 DGFEYGLGFFHGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQVR 238 DG E+G+ GAEIGI+ K+HARGPVG+E LTS KY V G GQVR Sbjct: 383 DGGEFGM----GAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVR 425 >MA4100 [E] COG0014 Gamma-glutamyl phosphate reductase Mac Methanosarcina acetivorans str.C2A Length = 447 Score = 237 bits (604), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 116/235 (49%), Positives = 161/235 (68%), Gaps = 6/235 (2%) Query: 5 ALITMTEYVDVIVPRGGKGLIERLIKESKVPMIKHLDGICHVYIDDKAELQKALDVAFNA 64 +L+++ YVD+++PRG ++ + +K+P++ H GICH+Y+D+ A+ A V F+A Sbjct: 192 SLLSLDAYVDLLIPRGSNEFVKFIQDNTKIPVLGHTSGICHIYVDEFADPDTAWKVCFDA 251 Query: 65 KCHRYGTCNTMETLLVARAVAAEVLPKLAELYRAKDVELRGDAESRRILA--GYPLLKEA 122 K CN +ETLLV R +A LPK+AE+Y VELR D +S +LA G L +A Sbjct: 252 KVQYPAVCNAIETLLVNRKIAEAFLPKMAEMYIKAGVELRCDKDSYILLAEKGLSPLSKA 311 Query: 123 VEEDWSTEYLAPILSVKIVAGMDEAIDHINTYSSQHTDAIVTEDYTRAMRFLREVDSASV 182 EEDWS EY ILS+K+V + EAI HINT+ S HTD I+TE+ +R F+ VDS+SV Sbjct: 312 TEEDWSLEYNDLILSIKLVDTIKEAIAHINTFGSHHTDGIITENASRRKEFIGLVDSSSV 371 Query: 183 MVNASTRFADGFEYGLGFFHGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQV 237 MVNASTRFADG+ YG GAE+GIS +K+H+RGPVG+EGL KY+++G+GQV Sbjct: 372 MVNASTRFADGYRYG----KGAEVGISTNKIHSRGPVGMEGLLIYKYILMGKGQV 422