BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0184.p (255 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl1283 [K] COG1414 Transcriptional regulator Cgl Corynebacteriu... 74 3e-13 BH1819 [K] COG1414 Transcriptional regulator Bha Bacillus halodu... 65 2e-10 Rv2989 [K] COG1414 Transcriptional regulator Mtu Mycobacterium t... 63 6e-10 STM3667 [K] COG1414 Transcriptional regulator Sty Salmonella typ... 62 1e-09 MT3067 [K] COG1414 Transcriptional regulator MtC Mycobacterium t... 62 1e-09 >Cgl1283 [K] COG1414 Transcriptional regulator Cgl Corynebacterium glutamicum Length = 235 Score = 73.9 bits (180), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 60/225 (26%), Positives = 104/225 (46%), Gaps = 12/225 (5%) Query: 25 EVGVAAVNRALMILDCFTSDESVLSLAVISKKTGLYKSTILRLVQSLEAYGYINRLISGS 84 E G+ ++R ++IL+ E SLA ++ T L ++T RL +LE +G + R Sbjct: 12 ESGIKVLDRTVLILNVIA--EQPRSLAELAAATDLPRATAHRLASALEVHGMLARSRDNR 69 Query: 85 YVLGAAPIKLASIASKALHP-AEKVMPVLRELAQTTSSSASFYVRTGEMRLCAYRVDSPR 143 + +GA +LAS+ ++ + +P++ +L + T S Y TG R C + Sbjct: 70 WTIGA---RLASLGARGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVASQEPSS 126 Query: 144 SIRDNVQAGQLLALDKGAGGHVLTAF------DNLSGDQLVQMPQPFIRVTRGERDSETA 197 +++ V G + L+ G+ V A+ S ++L Q+ + + GER+ A Sbjct: 127 GLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASVFSREELDQVRASGLAESVGERELGLA 186 Query: 198 AIACPVFGVNNRLEGALSLSGPLHHFNDEAVAAMIPHLIAAARVL 242 +++ PVF N + ALS+SG A LI AA L Sbjct: 187 SLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERL 231 >BH1819 [K] COG1414 Transcriptional regulator Bha Bacillus halodurans Length = 252 Score = 65.1 bits (157), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 51/242 (21%), Positives = 111/242 (45%), Gaps = 26/242 (10%) Query: 30 AVNRALMILDCFTSDESVLSLAVISKKTGLYKSTILRLVQSLEAYGYINRLISGSYVLGA 89 V +++ +L+ F + + L+L + K++G+ K+++ R++ SLE G++ + G+Y LG Sbjct: 7 TVIKSMNLLNLFRTYPT-LTLQEMVKQSGMPKTSVHRMINSLEEMGFLQKRHDGAYELGV 65 Query: 90 APIKLASIASKALHPAEKVMPVLRELAQTTSSSASFYVRTGEMRLCAYRVDSPRSIRDNV 149 ++L + S L + P++ L + VR G+ + ++D+ +R Sbjct: 66 VFLELGQLVSDRLDLRQVAFPIMEALRNQVEEAVHLTVRDGDEAIYIEKLDTLHPVRLFT 125 Query: 150 QAGQLLALDKGAGGHVLTAF-------------------DNLSGDQLV------QMPQPF 184 + G+ L GA V+ +F D D+L+ + Q Sbjct: 126 KVGRRAPLYAGACQRVILSFLPEQEQTAYLERVELIPLADGTITDKLLLKERISETQQTG 185 Query: 185 IRVTRGERDSETAAIACPVFGVNNRLEGALSLSGPLHHFNDEAVAAMIPHLIAAARVLTT 244 + ++ E ++ T AIA P++ + + +S++GP +E ++ + L AA+ ++ Sbjct: 186 VAISHSELENNTTAIAAPIYDHSGTIVAGISIAGPDIRVTEERLSTLKVTLKNAAKSISK 245 Query: 245 SL 246 L Sbjct: 246 QL 247 >Rv2989 [K] COG1414 Transcriptional regulator Mtu Mycobacterium tuberculosis H37Rv Length = 233 Score = 63.2 bits (152), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 57/212 (26%), Positives = 94/212 (44%), Gaps = 20/212 (9%) Query: 27 GVAAVNRALMILDCFTSDESVLSLAVISKKTGLYKSTILRLVQSLEAYGYINRLISGSYV 86 G+ +++A+ +L ES LA + +T L ++T RL +LE + + R G + Sbjct: 6 GIGVLDKAVGVLHAVA--ESPCGLAELCDRTDLPRATAYRLAAALEVHRLLGRGQDGHWR 63 Query: 87 LGAAPIKLAS-IASKALHPAEKVMPVLRELAQTTSSSASFYVRTGEMRLCAYRVDSPRSI 145 LG A +LA+ + L V+P LR+ T S Y R G R+C ++ + Sbjct: 64 LGPAITELATHVDDPLLVACAAVLPQLRD---ATGESVQVYRREGTSRVCVAALEPAAGL 120 Query: 146 RDNVQAGQLLALDKGAGGHVLTAFDNLSGDQLVQMPQPFIR-------VTRG------ER 192 RD V G L + G+G VL A + + Q +P+ RG ER Sbjct: 121 RDTVPVGARLPMTAGSGAKVLLAHTD-AATQAAVLPKAVFSARALAEVCRRGWAQSVAER 179 Query: 193 DSETAAIACPVFGVNNRLEGALSLSGPLHHFN 224 + A+++ PV + A+S+SGP+ Sbjct: 180 EPGVASVSAPVRDGRGVVIAAISVSGPIDRMG 211 >STM3667 [K] COG1414 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 266 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 59/231 (25%), Positives = 105/231 (45%), Gaps = 33/231 (14%) Query: 16 NEEGEPAADEVGVAAVNRALMILDCFTSDESVLSLAVISKKTGLYKSTILRLVQSLEAYG 75 N++ +PA G ++ R LM+++ ++ + LA +S+ GL KST+ RL+Q L++ G Sbjct: 5 NDKEKPA----GSQSLFRGLMLIEILSNYPNGCPLAHLSELAGLNKSTVHRLLQGLQSCG 60 Query: 76 YINRL-ISGSYVLGAAPIKLASIASKALHPAEKVMPVLRELAQTTSSSASFYVRTGEMRL 134 Y+ +GSY L I + A +L+ P L L TT + +F R + + Sbjct: 61 YVTPAPAAGSYRLTTKFIAVGQKALSSLNIIHVAAPHLEALNLTTGETVNFSSREDDHAI 120 Query: 135 CAYRVDSPRS-IRDNVQAGQLLALDKGAGGHVLTAF--------------DNLSG----- 174 Y+++ +R GQ + L A G + AF D + Sbjct: 121 LIYKLEPTTGMLRTRAYIGQHMPLYCSAMGKIYMAFGQPDYVASYWESHKDQIQPLTRNT 180 Query: 175 --------DQLVQMPQPFIRVTRGERDSETAAIACPVFGVNNRLEGALSLS 217 D+L Q+ + + + R E + + IA PVF +++R+ A+S+S Sbjct: 181 ITDLPAMYDELAQIRETSMAMDREENELGVSCIAVPVFDIHHRVPYAISIS 231 >MT3067 [K] COG1414 Transcriptional regulator MtC Mycobacterium tuberculosis CDC1551 Length = 267 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 94/208 (45%), Gaps = 20/208 (9%) Query: 27 GVAAVNRALMILDCFTSDESVLSLAVISKKTGLYKSTILRLVQSLEAYGYINRLISGSYV 86 G+ +++A+ +L ES LA + +T L ++T RL +LE + + R G + Sbjct: 40 GIGVLDKAVGVLHAVA--ESPCGLAELCDRTDLPRATAYRLAAALEVHRLLGRGQDGHWR 97 Query: 87 LGAAPIKLAS-IASKALHPAEKVMPVLRELAQTTSSSASFYVRTGEMRLCAYRVDSPRSI 145 LG A +LA+ + L V+P LR+ T S Y R G R+C ++ + Sbjct: 98 LGPAITELATHVDDPLLVACAAVLPQLRD---ATGESVQVYRREGTSRVCVAALEPAAGL 154 Query: 146 RDNVQAGQLLALDKGAGGHVLTAFDNLSGDQLVQMPQPFIR-------VTRG------ER 192 RD V G L + G+G VL A + + Q +P+ RG ER Sbjct: 155 RDTVPVGARLPMTAGSGAKVLLAHTD-AATQAAVLPKAVFSARALAEVCRRGWAQSVAER 213 Query: 193 DSETAAIACPVFGVNNRLEGALSLSGPL 220 + A+++ PV + A+S+SGP+ Sbjct: 214 EPGVASVSAPVRDGRGVVIAAISVSGPI 241