BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0181.p (200 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value paaY [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleuc... 244 7e-65 STM0069 [R] COG0663 Carbonic anhydrases/acetyltransferases, isol... 234 7e-62 caiE [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleuc... 232 5e-61 ZcaiE [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleu... 232 5e-61 ECs0038 [R] COG0663 Carbonic anhydrases/acetyltransferases, isol... 232 5e-61 >paaY [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Eco Escherichia coli K12 Length = 196 Score = 244 bits (624), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 115/186 (61%), Positives = 144/186 (77%) Query: 2 LQVYSIDGITPVVHPTAYVHPSAVLIGDVVVGPRCYIGPLASLRGDFGRIIINEGANIQD 61 + +Y IDG+TPVV ++VHP+AVLIGDV++G Y+GP ASLRGDFGRI++ +GANIQD Sbjct: 1 MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLRGDFGRIVVKDGANIQD 60 Query: 62 TCVLHGFYESDTVVDVDGHIGHGAILHGCKIERDALVGMNAIVMDDAVIGESSIVGAAAF 121 CV+HGF E DTVV DGHIGH AILHGC I R+ALVGMNA+VMD AVIGE+SIVGA+AF Sbjct: 61 NCVMHGFPEQDTVVGEDGHIGHSAILHGCIIRRNALVGMNAVVMDGAVIGENSIVGASAF 120 Query: 122 VKAGMIVPARSLVIGTPAKVVRDLREEEILWKRQGTSQYHELSVRSATTMKAVNALTEVE 181 VKA +PA L++G+PAK +R+L E+E+ WK+QGT +Y L R T+ V L E+E Sbjct: 121 VKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQVLVTRCKQTLHQVEPLREIE 180 Query: 182 ADRKRL 187 RKRL Sbjct: 181 PGRKRL 186 >STM0069 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Sty Salmonella typhimurium LT2 Length = 198 Score = 234 bits (598), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 106/198 (53%), Positives = 149/198 (75%) Query: 2 LQVYSIDGITPVVHPTAYVHPSAVLIGDVVVGPRCYIGPLASLRGDFGRIIINEGANIQD 61 + Y+ +G+ PVVHP A+VHPSAVLIGDV+VG YIGPLASLRGD+GR+I+ G+N+QD Sbjct: 1 MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQD 60 Query: 62 TCVLHGFYESDTVVDVDGHIGHGAILHGCKIERDALVGMNAIVMDDAVIGESSIVGAAAF 121 C++HG+ ++DT+V +GHIGHGAILHGC + RDALVGMN+++MD AVIGE SIV A +F Sbjct: 61 GCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSF 120 Query: 122 VKAGMIVPARSLVIGTPAKVVRDLREEEILWKRQGTSQYHELSVRSATTMKAVNALTEVE 181 VKAG AR L++G+PA+V+R + ++E+ WK T +Y +L++R T + LT+ E Sbjct: 121 VKAGFQGEARQLLVGSPARVLRQVTDQELHWKHLNTKEYQDLAIRCRTGLSETKPLTQAE 180 Query: 182 ADRKRLQCSSAPKSKNRQ 199 +R RL+ ++ K K+ Q Sbjct: 181 ENRPRLKGTTDVKPKSAQ 198 >caiE [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Eco Escherichia coli K12 Length = 203 Score = 232 bits (591), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 107/187 (57%), Positives = 143/187 (76%) Query: 5 YSIDGITPVVHPTAYVHPSAVLIGDVVVGPRCYIGPLASLRGDFGRIIINEGANIQDTCV 64 Y+ +G+ PVVHPTA+VHPSAVLIGDV+VG YIGPLASLRGD+GR+I+ GANIQD C+ Sbjct: 11 YAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCI 70 Query: 65 LHGFYESDTVVDVDGHIGHGAILHGCKIERDALVGMNAIVMDDAVIGESSIVGAAAFVKA 124 +HG+ ++DT+V +GHIGHGAILHGC I RDALVGMN+++MD AVIGE SIV A +FVKA Sbjct: 71 MHGYCDTDTIVGENGHIGHGAILHGCLIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKA 130 Query: 125 GMIVPARSLVIGTPAKVVRDLREEEILWKRQGTSQYHELSVRSATTMKAVNALTEVEADR 184 G R L++GTPA+ VR++ ++E+ WKR T +Y +L R ++ L ++E +R Sbjct: 131 GFRGEKRQLLMGTPARAVRNVSDDELHWKRLNTKEYQDLVGRCHVSLHETQPLRQMEENR 190 Query: 185 KRLQCSS 191 RLQ ++ Sbjct: 191 PRLQGTT 197 >ZcaiE [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 203 Score = 232 bits (591), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 107/187 (57%), Positives = 142/187 (75%) Query: 5 YSIDGITPVVHPTAYVHPSAVLIGDVVVGPRCYIGPLASLRGDFGRIIINEGANIQDTCV 64 Y+ +G+ PVVHPTA+VHPSAVLIGDV+VG YIGPLASLRGD+GR+I+ GANIQD C+ Sbjct: 11 YAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCI 70 Query: 65 LHGFYESDTVVDVDGHIGHGAILHGCKIERDALVGMNAIVMDDAVIGESSIVGAAAFVKA 124 +HG+ ++DT+V +GHIGHGAILHGC I RDALVGMN+++MD AVIGE SIV A +FVKA Sbjct: 71 MHGYTDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKA 130 Query: 125 GMIVPARSLVIGTPAKVVRDLREEEILWKRQGTSQYHELSVRSATTMKAVNALTEVEADR 184 G R L++GTPA+ VR + ++E+ WKR T +Y +L R ++ L ++E +R Sbjct: 131 GFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENR 190 Query: 185 KRLQCSS 191 RLQ ++ Sbjct: 191 PRLQGTT 197 >ECs0038 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Ecs Escherichia coli O157:H7 Length = 203 Score = 232 bits (591), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 107/187 (57%), Positives = 142/187 (75%) Query: 5 YSIDGITPVVHPTAYVHPSAVLIGDVVVGPRCYIGPLASLRGDFGRIIINEGANIQDTCV 64 Y+ +G+ PVVHPTA+VHPSAVLIGDV+VG YIGPLASLRGD+GR+I+ GANIQD C+ Sbjct: 11 YAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCI 70 Query: 65 LHGFYESDTVVDVDGHIGHGAILHGCKIERDALVGMNAIVMDDAVIGESSIVGAAAFVKA 124 +HG+ ++DT+V +GHIGHGAILHGC I RDALVGMN+++MD AVIGE SIV A +FVKA Sbjct: 71 MHGYTDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKA 130 Query: 125 GMIVPARSLVIGTPAKVVRDLREEEILWKRQGTSQYHELSVRSATTMKAVNALTEVEADR 184 G R L++GTPA+ VR + ++E+ WKR T +Y +L R ++ L ++E +R Sbjct: 131 GFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENR 190 Query: 185 KRLQCSS 191 RLQ ++ Sbjct: 191 PRLQGTT 197