BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0149.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 261 2e-69 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 253 5e-67 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 236 6e-62 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 233 7e-61 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 228 2e-59 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 261 bits (668), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 158/425 (37%), Positives = 242/425 (56%), Gaps = 13/425 (3%) Query: 3 LQAEKQ-LIGLVSKRLQWILLLMMFIAFMDRTNISFVASFMNKDIGLSARQFGWGASLFF 61 L A++Q +I + +RL L L+ AF+DR NI F M KD+GLSA FG +LF+ Sbjct: 21 LSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFY 80 Query: 62 VGYLLFEIPSNLIMARVGARLWLARIMISWGIVSCASAFIVGPNSFYLARFLLGVAEAGF 121 V Y+LF IPSN+++ VGAR W+A IM+ WGI S A+ F VGPNS YL R ++G+ EAGF Sbjct: 81 VTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGF 140 Query: 122 IPGVVLYLSYWVPHRYLGKFTGWFLMIVPISASLTAMLTAVLLGLDEVLGVTGWRWVFFT 181 +PG+++YL+YW P + + F++ +P++ +L ++++ +L LD L + GW+W+F Sbjct: 141 LPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLL 200 Query: 182 EGLPAIVVGFFLLRYLADKPASATWLSTDQRTQLQAMVNAD--QVGKMTETPKLKPA--- 236 EG P++++G + YL D P A WL+ + + LQ M+ +D Q+ K + L + Sbjct: 201 EGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESDRLQLAKQADYGALPQSAMW 260 Query: 237 --LTSPSVWCLGGAYFFMNVALGA-QTWYPLSIHLFKLSRPWETASI--AIPSAIASLSM 291 + +P V AYF + L A W P + F S T + AIP M Sbjct: 261 REIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGM 320 Query: 292 LLWAKRSDRGEERSWYVIIPALVSALSWYGAAHWINDAFWLPALMSVAYSAMFAALVVFW 351 + W++RSDR +ER + ++P L +A W A+ N L ++ +A + F A+ +FW Sbjct: 321 IWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGII-MASTGSFTAMAIFW 379 Query: 352 TIPTRVLSVEARPAGLAIITALGLPGSMISLALGGQLRDQLGSFAPCYLMAASGMLACGL 411 T P + +S+ AR G+A+I A G GS +S L G L+DQ G+F A G+L G Sbjct: 380 TTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQTGNFNSGLYFVA-GLLVIGA 438 Query: 412 VVVWM 416 V+ M Sbjct: 439 VIFLM 443 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 253 bits (647), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 144/425 (33%), Positives = 240/425 (56%), Gaps = 15/425 (3%) Query: 5 AEKQLIGLVSKRLQWILLLMMFIAFMDRTNISFVASFMNKDIGLSARQFGWGASLFFVGY 64 ++ +I + +RL L ++ +F+DR NI F M +D+GLSA FG +LF+ Y Sbjct: 24 GQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYATY 83 Query: 65 LLFEIPSNLIMARVGARLWLARIMISWGIVSCASAFIVGPNSFYLARFLLGVAEAGFIPG 124 ++F IPSN++++ VGAR W+A IM+ WGI S A+ F VGP S Y+ R L+G+ EAGF+PG Sbjct: 84 VIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPG 143 Query: 125 VVLYLSYWVPHRYLGKFTGWFLMIVPISASLTAMLTAVLLGLDEVLGVTGWRWVFFTEGL 184 ++LYL+YW P + + F++ +P + +L ++++ +L LD + + GW+W+F EG Sbjct: 144 ILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGF 203 Query: 185 PAIVVGFFLLRYLADKPASATWLSTDQRTQLQAMVNADQV------GKMTETPKLKPAL- 237 P++++G + YL D PA A WL+ + + LQ M+++D++ G ++ + +L Sbjct: 204 PSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSDRLTLVQPEGAISHNAMQQRSLW 263 Query: 238 ---TSPSVWCLGGAYFFMNVALGA-QTWYPLSIHLFKLSRPWETASI--AIPSAIASLSM 291 +P V AYF + L A W P + F T + AIP L M Sbjct: 264 REVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTILGM 323 Query: 292 LLWAKRSDRGEERSWYVIIPALVSALSWYGAAHWINDAFWLPALMSVAYSAMFAALVVFW 351 + W++ SD+ +ER + +P L +A W A+ ++ L ++ +A + F+A+ +FW Sbjct: 324 IYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIV-MASTGSFSAMAIFW 382 Query: 352 TIPTRVLSVEARPAGLAIITALGLPGSMISLALGGQLRDQLGSFAPCYLMAASGMLACGL 411 T P + +S+ AR G+A+I A G GS +S + G L+D GSF AS +L G Sbjct: 383 TTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLKDITGSFNSGLWFVAS-LLVVGA 441 Query: 412 VVVWM 416 ++W+ Sbjct: 442 AIIWL 446 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 236 bits (603), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 150/408 (36%), Positives = 230/408 (56%), Gaps = 6/408 (1%) Query: 6 EKQLIGLVSKRLQWILLLMMFIAFMDRTNISFVASFMNKDIGLSARQFGWGASLFFVGYL 65 E+ VS RL LLL +A++DR N+ F M D+ S +G GA +FF+GY Sbjct: 24 EEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYF 83 Query: 66 LFEIPSNLIMARVGARLWLARIMISWGIVSCASAFIVGPNSFYLARFLLGVAEAGFIPGV 125 LFE+PSN+I+ RVGAR+W+ARIMISWG++S A F+ P FY+ RFLLG+AEAGF PG+ Sbjct: 84 LFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGI 143 Query: 126 VLYLSYWVPHRYLGKFTGWFLMIVPISASLTAMLTA-VLLGLDEVLGVTGWRWVFFTEGL 184 +LYL+YW P G+ T +F+ V +S + ++ L V G+ GW+W+F EG+ Sbjct: 144 ILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGI 203 Query: 185 PAIVVGFFLLRYLADKPASATWLSTDQRTQLQAMVNADQVGKMTETPKLKPALTSPSVWC 244 P++V+G +L YL ++ + A WL+ +++ L + A++ K E + + SP VW Sbjct: 204 PSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQK--EDAPIAAIMASPRVWL 261 Query: 245 LGGAYFFMNVAL-GAQTWYPLSIHLFKLSRPWETASI-AIPSAIASLSMLLWAKRSDRGE 302 + YF + L G W P I ++ P + AIP A ++M+L A+ +DR Sbjct: 262 MSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTR 321 Query: 303 ERSWYVIIPALVSALSWYGAAHWINDAFWLPALMSVAYSAMFAALVVFWTIPTRVLSVEA 362 ER W++ IPAL A+ +A W + A +++ + L +FW++PT L+ Sbjct: 322 ERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTG 381 Query: 363 RPAGLAIITALGLPGSMISLALGGQLRDQLGSF-APCYLMAASGMLAC 409 AG+A+I +LG +S G L+D S + YL+AAS +L Sbjct: 382 AAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGA 429 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 233 bits (594), Expect = 7e-61, Method: Compositional matrix adjust. Identities = 145/406 (35%), Positives = 225/406 (55%), Gaps = 15/406 (3%) Query: 6 EKQLIGLVSKRLQWILLLMMFIAFMDRTNISFVASFMNKDIGLSARQFGWGASLFFVGYL 65 E+ +G V++RL + LM IA++DR N+S+ M +GLS +G GASLFF+GY Sbjct: 9 ERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGASLFFIGYF 68 Query: 66 LFEIPSNLIMARVGARLWLARIMISWGIVSCASAFIVGPNSFYLARFLLGVAEAGFIPGV 125 LFE P+NLI+ARVGAR+W ARIM SWG+V+ A F FY+ RFLLGVAEAGF PGV Sbjct: 69 LFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAEAGFFPGV 128 Query: 126 VLYLSYWVPHRYLGKFTGWFLMIVPISASLTAMLTAVLLGLDEVLGVTGWRWVFFTEGLP 185 + L+ W P + + G F++ + ++ A + +LLG+D LG+ GW+WVF G P Sbjct: 129 LYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGGLLLGMDGFLGLAGWQWVFLVTGAP 188 Query: 186 AIVVGFFLLRYLADKPASATWLSTDQRTQLQAMVNADQVGKMTETPKLKPALTSPSVWCL 245 A+++ ++L L P+ A WL +++ L + + A++ G++ + A+ P V L Sbjct: 189 AVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAERGGEVDDHRGAWKAIFDPRVLML 248 Query: 246 GGAYFFMNV-ALGAQTWYPLSIHLFKLSRPWETASIAIPSAIASLSMLLWAKRSDRGEER 304 G Y M + A G W P + F +S IP + ++++ + + R Sbjct: 249 AGLYIGMPLSAYGLSYWLPTIVKSFGVSNTVNGFINVIPWLLVAVALWFVPRHAARHGAS 308 Query: 305 SWYVIIPALVSALSWYGAAHWINDAFWLPA------LMSVAYSAMFAALVVFWTIPTRVL 358 +W++ P L++A++ ++ + LP ++ +A A+FAA VFW++P L Sbjct: 309 AWHIAGPVLLAAVA-------LSLSVILPGAALKFTMLCIAAPAIFAAQPVFWSLPPSFL 361 Query: 359 SVEARPAGLAIITALGLPGSMISLALGGQLRDQLGS-FAPCYLMAA 403 S AG+A I A+G G I+ L +RD GS AP +AA Sbjct: 362 SGPRAAAGIATINAVGNLGGFIAQNLVPVVRDATGSELAPMLALAA 407 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 228 bits (581), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 145/424 (34%), Positives = 222/424 (52%), Gaps = 3/424 (0%) Query: 5 AEKQLIGLVSKRLQWILLLMMFIAFMDRTNISFVASFMNKDIGLSARQFGWGASLFFVGY 64 +EK LI ++ RL L L+ IA++DR N+S+ M + LS +G GASLFF+GY Sbjct: 65 SEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGY 124 Query: 65 LLFEIPSNLIMARVGARLWLARIMISWGIVSCASAFIVGPNSFYLARFLLGVAEAGFIPG 124 LFE+PSNL + R GA W ARI++SWG V+ A A+ FY+ RFLLG+ EAGF PG Sbjct: 125 FLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPG 184 Query: 125 VVLYLSYWVPHRYLGKFTGWFLMIVPISASLTAMLTAVLLGLDEVLGVTGWRWVFFTEGL 184 V+ ++ W P Y G+ G F++ ++ ++ A L +LL LD LG GW WVF G+ Sbjct: 185 VLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATGI 244 Query: 185 PAIVVGFFLLRYLADKPASATWLSTDQRTQLQAMVNADQVGKMTETPKLKPALTSPSVWC 244 PA++ G YL D P A +L+ D++ L+ + + G AL +P V Sbjct: 245 PAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALVNPRVLF 304 Query: 245 LGGAYF-FMNVALGAQTWYPLSIHLFKLSRPWETASIAIPSAIASLSMLLWAKRSDRGEE 303 + Y F A G W P + F +S IP I ++++ + +D+ + Sbjct: 305 MALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKAKN 364 Query: 304 RSWYVIIPALVSALSWYGAAHWINDAFWLPALMSVAYSAMFAALVVFWTIPTRVLSVEAR 363 ++ Y++ PA V A +A ++D A + VA + +FA VFW++P R L Sbjct: 365 KTPYIVGPAFVGAFCLLMSA-LLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGA 423 Query: 364 PAGLAIITALGLPGSMISLALGGQLRDQLGS-FAPCYLMAASGMLACGLVVVWMHLSDQR 422 AG+A I ++G G ++ + ++DQ GS AP + +A LA LV++ + Sbjct: 424 AAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLVIIATRKMGNQ 483 Query: 423 KKVA 426 K A Sbjct: 484 VKAA 487