BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0140.p (450 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4654 [GEPR] COG0477 Permeases of the major facilitator superfa... 161 3e-39 CC2485 [GEPR] COG0477 Permeases of the major facilitator superfa... 99 1e-20 CC0336 [GEPR] COG0477 Permeases of the major facilitator superfa... 96 1e-19 CC2486 [GEPR] COG0477 Permeases of the major facilitator superfa... 87 7e-17 CC1819 [GEPR] COG0477 Permeases of the major facilitator superfa... 69 3e-11 >PA4654 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 457 Score = 161 bits (407), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 126/409 (30%), Positives = 194/409 (47%), Gaps = 10/409 (2%) Query: 4 QNGSPRSKFGQWGLVVTLTILSMLAQLDKNILVLMVAPIQKTYGVSDVEISFLIGAAFAI 63 NG P S W V L + +L+ +D+ IL L+V PI++ +SD E+S L+G +FA+ Sbjct: 5 NNGYP-SNLAAWTTVAILMVAYVLSFIDRQILNLLVGPIRRDLAISDTEMSLLMGLSFAL 63 Query: 64 ANIVVGIPAGWMADKWNRRVVIAAGVVIWSLALSANAVAATFLGLVVARVIVGGAEALIP 123 + GIP G MAD +RR +I GV++WS +A +A ++ + RV VG EA + Sbjct: 64 FYTLCGIPLGRMADNRSRRGLILFGVLVWSAMTAACGLARSYWQFLTFRVGVGVGEAALS 123 Query: 124 PSSYSLIRDGVDEDRRARALSIYTMALMLGTGLSLVLGGPLLAAVHNAGWTYIPVLGHVT 183 P++YSLI D +RRA A+S+Y+M + LG+GL+ +LGG ++ G ++P+ G V Sbjct: 124 PAAYSLIADSFPRERRATAISVYSMGIYLGSGLAFLLGGLVIKFASAQGDVHLPLFGEVR 183 Query: 184 SWQFTLFLIGAVGLPLALTVFLNRDPGRSAAAPAELAASNARASSLPNYLWMNRAFFIPI 243 WQ ++GA G+ L + R+P R A + YL NR + Sbjct: 184 PWQLIFLILGAAGVLFCLLLLAIREPARRGVG----AGVAVPLGEVGAYLRANRKTVLCH 239 Query: 244 LLFVVANAIITFGMAAWLPAMAGRKFMLEMRTFGLSQGIIMLTAGPLGLWLAGIAMQKKN 303 + +G AW+P R + G+ G I+ G LG+ G Sbjct: 240 NFGFACLSFAGYGSGAWVPTFFVRTHGWDAGHVGVVYGSIVAVFGCLGIVFGGRLADYWA 299 Query: 304 ANNPLGRIISVGLVSSLAMAVMPTALV--LSTSLQWFWTINCFVVLSSWTFMSVTSVVIA 361 + VGL++ A AV+P LV L + W + V V I Sbjct: 300 KRGRSDANMRVGLLA--AWAVIPFTLVYPLLDNANWAAALMAPTVFFLSMPFGVAPAAIQ 357 Query: 362 RTVPAASVGLVMAMVLFLNGLVGQGFSPTLIALVGRYVYGGGEHALPYA 410 +P + G A+ LF+ L G G PT +ALV +V+ + AL Y+ Sbjct: 358 EIMPNSMRGQASAIYLFVVTLFGLGVGPTAVALVTDFVF-ADDMALRYS 405 >CC2485 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 444 Score = 99.4 bits (246), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 93/325 (28%), Positives = 152/325 (46%), Gaps = 44/325 (13%) Query: 1 VIVQNGSPRSKFGQWGLVVTLTILSMLAQLDKNILVLMVAPIQKTYGVSDVEISFLIGAA 60 VI + ++ W L++ T L LD+ ++ ++ PI++ G++D ++ + G A Sbjct: 10 VIAPVSTAYRRYALWVLLIIYT----LNFLDRQVVNILAEPIKRDLGLADWQLGMMTGLA 65 Query: 61 FAIANIVVGIPAGWMADKWNRRVVIAAGVVIWSLALSANAVAATFLGLVVARVIVGGAEA 120 FAI V+GIP MA+ NR +I V +WS A F L++AR+ VG EA Sbjct: 66 FAIFYTVLGIPIARMAETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGVGVGEA 125 Query: 121 LIPPSSYSLIRDGVDEDRRARALSIYTMALMLGTGLSLVLGGPLLAAVHNAGWTYIPVLG 180 P ++SLI D V +++RA A++ Y++ LGT + +GG ++ Sbjct: 126 GCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTLAGMAMGG---------------LVA 170 Query: 181 HVTSWQFTLFLIGAVGLPLAL-TVFLNRDPGRSAAAPAELAASNARASSLPNY------L 233 W+ + GA GL AL F +P + A AE+A ARAS+ ++ L Sbjct: 171 DAYGWRVAFMVAGAPGLLFALIAAFTLVEPRKKLA--AEMA---ARASTQISFAAALAVL 225 Query: 234 WMNRAFFIPILLFVVANAIITFGMAAWLPAMAGRKFMLEMR----TFGLSQ--------G 281 + F++ + L A I +G A ++ + R E+ TFGL G Sbjct: 226 ATKKTFWL-VALAASIKAFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALG 284 Query: 282 IIMLTAGPLGLWLAGIAMQKKNANN 306 +I TAG +G WL G+ + A + Sbjct: 285 LINGTAGVIGAWLGGVLADRLGAKD 309 >CC0336 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 438 Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 21/283 (7%) Query: 30 LDKNILVLMVAPIQKTYGVSDVEISFLIGAAFAIANIVVGIPAGWMADKWNRRVVIAAGV 89 LD+ IL ++ I+ ++D ++ + G AFA +G+P W+AD+ +R ++ + Sbjct: 39 LDRQILGILAGSIKAELHLTDTQLGLMGGVAFAALYTTLGVPLAWLADRVSRTWIMTVAL 98 Query: 90 VIWSLALSANAVAATFLGLVVARVIVGGAEALIPPSSYSLIRDGVDEDRRARALSIYTMA 149 +WS +A F L +AR+ VG EA +YSLI D +++RARAL++Y+ Sbjct: 99 TVWSGFTVVCGLAGGFWSLFLARMGVGVGEAGGVAPAYSLIADYFPKEQRARALAVYSFG 158 Query: 150 LMLGTGLSLVLGGPLLAAVHNAGWTYIPVLGHVTSWQFTLFLIGAVGLPLA-LTVFLNRD 208 + LGT L ++ GG + A V W+F +G G+ A + ++ +D Sbjct: 159 IPLGTALGVLFGGLIAAYV---------------DWRFAFIAVGLAGVAFAPIFKWVVKD 203 Query: 209 PGRSA--AAPAELAASNARASSLPNYLW---MNRAFFIPILLFVVANAIITFGMAAWLPA 263 P R AP E+A + + + M + F + ++I +G+A WLP Sbjct: 204 PVRGGLDRAPGEVAPAEPPKAPAFGQVLATVMPKPSFWLLSFGAACSSICGYGVAFWLPT 263 Query: 264 MAGRKFMLEMRTFGLSQGIIMLTAGPLGLWLAGIAMQKKNANN 306 R F L + L + L G G+WL G+ + A N Sbjct: 264 FFQRSFGLSLTDRALYYSALSLFGGVAGIWLGGVLADRFGAKN 306 >CC2486 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 519 Score = 87.0 bits (214), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 106/392 (27%), Positives = 170/392 (43%), Gaps = 58/392 (14%) Query: 30 LDKNILVLMVAPIQKTYGVSDVEISFLIGAAFAIANIVVGIPAGWMADKWNRRVVIAAGV 89 +D+ I+ + I+ ++D ++ L G FA+ ++GIP +A+++NR +I+ + Sbjct: 57 IDRTIISTIGQAIKVDLKLTDTQLGLLGGLYFALLYTILGIPIARLAERFNRVTIISVSL 116 Query: 90 VIWSLALSANAVAATFLGLVVARVIVGGAEALIPPSSYSLIRDGVDEDRRARALSIYTMA 149 VIWS + AA F L + R VG EA P S+SLI D + +RA ALSIY+ Sbjct: 117 VIWSGFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDYYEPKKRATALSIYSFG 176 Query: 150 LMLGTGLSLVLGGPLLAAVHNAGWTYIPVLGHVTSWQFTLFLIGAVGLPLALTVFL-NRD 208 + LGT V G GW L SW+ ++G G+ LA+ V L ++ Sbjct: 177 IPLGTMFGAVAG----------GW-----LAQEFSWRVAFVIVGLPGILLAVIVKLVVKE 221 Query: 209 PGRSAAAPAE--LAASN------ARASSLPN---YLW-MNRAFF--IPILLFVVANAIIT 254 P R + E L A + A S+ N LW + + F P+L V+ I + Sbjct: 222 PPRGHSEIVERPLEAEDVVVEPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIAS 281 Query: 255 FGM---AAWLPAMAGRKFMLEMRTFGLSQGII--------MLTAGPLGLWLAGIAMQKKN 303 FG A++P+ R F L + GL G+I L G L W AG K Sbjct: 282 FGAYGSGAFVPSYFVRAFDLGLAQVGLITGLIGGFSAGVGTLVGGFLSDW-AGKRSAKWY 340 Query: 304 ANNPLGRIISVGLVSSLAMAVMPTALVLSTSLQWFWTINCFVVLS----SWTFMSVTSVV 359 A P ++GL ++ T + + LQ W ++L + +++ T V Sbjct: 341 ALTP-----AIGL-------ILCTPIYILAYLQTDWQTTALILLVPGIFHYVYLAPTFGV 388 Query: 360 IARTVPAASVGLVMAMVLFLNGLVGQGFSPTL 391 + +V A++ F ++ G P Sbjct: 389 VQNSVEPRRRATATALLFFFLNIIALGVGPVF 420 >CC1819 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 479 Score = 68.6 bits (166), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 44/144 (30%), Positives = 80/144 (55%), Gaps = 3/144 (2%) Query: 7 SPRSKFGQWGLVVTLTILSMLAQLDKNILVLMVAPIQKTYGVSDVEISFLIGAAFAIANI 66 S R + GL++ + L+ML D+ I+ ++ P++ ++D +I + G AFA+ Sbjct: 44 SDRYRRYALGLLMLIYALNML---DRQIITILAEPMKAELNLADWQIGAVSGLAFALFYS 100 Query: 67 VVGIPAGWMADKWNRRVVIAAGVVIWSLALSANAVAATFLGLVVARVIVGGAEALIPPSS 126 VG+P AD+ +R +IA + +WS + +A TF L++AR+ VG EA P++ Sbjct: 101 AVGLPMARFADRGDRVRLIAISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAA 160 Query: 127 YSLIRDGVDEDRRARALSIYTMAL 150 +SLI + + A AL+ Y++ + Sbjct: 161 HSLITEFTPRAKLASALAFYSLGI 184