BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0127.p (444 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 277 4e-74 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 276 6e-74 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 254 4e-67 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 254 4e-67 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 253 8e-67 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 277 bits (708), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 161/431 (37%), Positives = 254/431 (58%), Gaps = 16/431 (3%) Query: 9 VNEVIDSRPVGGLQWCSIVTCILIAVLDGFDTQTIGMLAPAMSKDLGIPISQFGPIFSAG 68 V +D + QW ++ C + +DGFDT +G +APA+++D I + G +FSAG Sbjct: 10 VRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTVFSAG 69 Query: 69 LLGMLIGAVVLGPMADRFGRKTMVVLSTIIFGVLSFATAYASGHDELLVLRFLTGIGLGG 128 L G+++GA++ GP+ADR GRK ++ + FG+ S +A+A L+ LRFLTG+GLGG Sbjct: 70 LAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGLGLGG 129 Query: 129 ALPNALALASEYSPRRYSRVIVSTLMCGMPLGAVLGGIVASILLPLHGWHSVFMVGGVLP 188 A+PNA+AL SEY P R + + + CG LG+ GGIVA+ L+P GW SV + GGV+P Sbjct: 130 AMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFGGVIP 189 Query: 189 VAVALFAIAFMPESARFLILRNQSDRRLGAIMHRIAP-DLPREQQF--HVPLSR-STGVP 244 + + + +PES R+L+ + +G +++RIAP + + +F H ++ + G P Sbjct: 190 LLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKGAPGSP 249 Query: 245 IGELFSKGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLVGAHHPVSVGIAAIS----FFS 300 + +LF T+LLW +FM+L+++Y + +W+P ++ H V +A S + Sbjct: 250 VRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLI----HSGGVALALASRIAVMYQ 305 Query: 301 GGGVVGCLLQGWLMNSFGVRKVLVTELVLYAVLAAVLANWPSSYATVVVVS-TLMGVVIQ 359 GG VG L+ G +M+ + VL Y + A L S T++ ++ T +G I Sbjct: 306 LGGTVGALVIGRMMDRYPATVVLCCT---YGLGAGFLVLTGVSQGTMLAIAVTGVGFCIS 362 Query: 360 GAQAGFNVLATEIYPTHMRATGVGFAIGIGRIGSICGPLSGGLMLALQLDVKHIFLMGIA 419 G+Q G N A + YPT R TG+ +A+GIGR+GS+CG L GG++LA + + +FL+ Sbjct: 363 GSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAV 422 Query: 420 PALLASLAILL 430 PA +ASLAI L Sbjct: 423 PAAIASLAIFL 433 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 276 bits (707), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 156/410 (38%), Positives = 244/410 (59%), Gaps = 3/410 (0%) Query: 7 LYVNEVIDSRPVGGLQWCSIVTCILIAVLDGFDTQTIGMLAPAMSKDLGIPISQFGPIFS 66 L V I+++P+ QW ++ C LI LDG DT +G +APA+++D GI + GP+ S Sbjct: 12 LDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPVMS 71 Query: 67 AGLLGMLIGAVVLGPMADRFGRKTMVVLSTIIFGVLSFATAYASGHDELLVLRFLTGIGL 126 A L+GM+ GA+ GP+ADR+GRK ++V + +FG+ S A+AY++ ++LL LRFLTG+GL Sbjct: 72 AALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGLGL 131 Query: 127 GGALPNALALASEYSPRRYSRVIVSTLMCGMPLGAVLGGIVASILLPLHGWHSVFMVGGV 186 G A+PNA L SEY+P R ++V+++ CG LG GG V++ L+PL GWHS+ ++GG+ Sbjct: 132 GAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLGGL 191 Query: 187 LPVAVALFAIAFMPESARFLILRNQSDRRLGAIMHRIAP-DLPREQQFHVPLSRSTGVP- 244 LP+ +A+ + +PESAR+L++RN+ R+ ++ IAP + + FHVP ++ Sbjct: 192 LPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVPEQQTVQARN 251 Query: 245 -IGELFSKGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLVGAHHPVSVGIAAISFFSGGG 303 +FS T+LLW+ YFM LV++Y + SW+P ++ + + + F GG Sbjct: 252 VFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGALFQFGG 311 Query: 304 VVGCLLQGWLMNSFGVRKVLVTELVLYAVLAAVLANWPSSYATVVVVSTLMGVVIQGAQA 363 V+ + GW M+ F KV+ +L V A + + + L G+ I GAQ+ Sbjct: 312 VLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLAGMCINGAQS 371 Query: 364 GFNVLATEIYPTHMRATGVGFAIGIGRIGSICGPLSGGLMLALQLDVKHI 413 LA YPT RATGV + +GIGR G+I G G +L L + + + Sbjct: 372 AMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWNFEQV 421 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 254 bits (648), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 151/425 (35%), Positives = 243/425 (57%), Gaps = 5/425 (1%) Query: 9 VNEVIDSRPVGGLQWCSIVTCILIAVLDGFDTQTIGMLAPAMSKDLGIPISQFGPIFSAG 68 + +ID+ PVG +QW I+ C L+ +LDGFDT IG +AP + + P+F AG Sbjct: 7 LQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGAG 66 Query: 69 LLGMLIGAVVLGPMADRFGRKTMVVLSTIIFGVLSFATAYASGHDELLVLRFLTGIGLGG 128 LL + GA++ GP++DRFGRK ++ L +FG LS A+A++ L+ LRFLTG+GLGG Sbjct: 67 LLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLGG 126 Query: 129 ALPNALALASEYSPRRYSRVIVSTLMCGMPLGAVLGGIVASILLPLHGWHSVFMVGGVLP 188 A+PN + + SEY P R +V+ + CG LG+ GGIV++ L+P+ GWH + ++GGVLP Sbjct: 127 AMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLP 186 Query: 189 VAVALFAIAFMPESARFLILRNQSDRRLGAIMHRIAPDLPREQQFHVPLSRS-TGVPIGE 247 + + + + +PES R+ + R + + I + + F++ S S T I + Sbjct: 187 LMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIRQ 246 Query: 248 LFSKGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLVGAHHPVSVGIAA--ISFFSGGGVV 305 LF + T++LW+ +FM+L+++Y + SWMP +L H + + A+ + F GG + Sbjct: 247 LFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLL--NHRGIDLQHASWVTAAFQIGGTL 304 Query: 306 GCLLQGWLMNSFGVRKVLVTELVLYAVLAAVLANWPSSYATVVVVSTLMGVVIQGAQAGF 365 G L G LM+ F +VL + A+ ++ + + G+ I G+Q G Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 366 NVLATEIYPTHMRATGVGFAIGIGRIGSICGPLSGGLMLALQLDVKHIFLMGIAPALLAS 425 N L +YPT RATGV ++ IGR G+I G LSGG+M+A+ +F + PA +++ Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 426 LAILL 430 + + L Sbjct: 425 VMLTL 429 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 254 bits (648), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 152/425 (35%), Positives = 244/425 (57%), Gaps = 5/425 (1%) Query: 9 VNEVIDSRPVGGLQWCSIVTCILIAVLDGFDTQTIGMLAPAMSKDLGIPISQFGPIFSAG 68 + +ID+ PVG +QW I+ C L+ +LDGFDT IG +AP + + P+F AG Sbjct: 7 LQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGAG 66 Query: 69 LLGMLIGAVVLGPMADRFGRKTMVVLSTIIFGVLSFATAYASGHDELLVLRFLTGIGLGG 128 LLG+ GA++ GP++DRFGRK ++ L +FG LS A+A++ L+ LRFLTG+GLGG Sbjct: 67 LLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLGG 126 Query: 129 ALPNALALASEYSPRRYSRVIVSTLMCGMPLGAVLGGIVASILLPLHGWHSVFMVGGVLP 188 A+PN + + SEY P R +V+ + CG LG+ GGIV++ L+P+ GWH + ++GGVLP Sbjct: 127 AMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLP 186 Query: 189 VAVALFAIAFMPESARFLILRNQSDRRLGAIMHRIAPDLPREQQFHVPLSRS-TGVPIGE 247 + + + + +PES R+ + R + + I + + F++ S S T I + Sbjct: 187 LMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIRQ 246 Query: 248 LFSKGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLVGAHHPVSVGIAA--ISFFSGGGVV 305 LF + T++LW+ +FM+L+++Y + SWMP +L H + + A+ + F GG + Sbjct: 247 LFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLL--NHRGIDLQHASWVTAAFQIGGTL 304 Query: 306 GCLLQGWLMNSFGVRKVLVTELVLYAVLAAVLANWPSSYATVVVVSTLMGVVIQGAQAGF 365 G L G LM+ F +VL + A+ ++ + + G+ I G+Q G Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 366 NVLATEIYPTHMRATGVGFAIGIGRIGSICGPLSGGLMLALQLDVKHIFLMGIAPALLAS 425 N L +YPT RATGV ++ IGR G+I G LSGG+M+A+ +F + PA +++ Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 426 LAILL 430 + + L Sbjct: 425 VMLTL 429 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 253 bits (645), Expect = 8e-67, Method: Compositional matrix adjust. Identities = 154/409 (37%), Positives = 229/409 (55%), Gaps = 3/409 (0%) Query: 9 VNEVIDSRPVGGLQWCSIVTCILIAVLDGFDTQTIGMLAPAMSKDLGIPISQFGPIFSAG 68 V EVID + Q + C A+LDGFDT IG +APA+ + + Q P F AG Sbjct: 12 VREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPAFGAG 71 Query: 69 LLGMLIGAVVLGPMADRFGRKTMVVLSTIIFGVLSFATAYASGHDELLVLRFLTGIGLGG 128 L G+++G++ LGP+ADRFGRK ++++S ++FGV + A A + + L++LRFLTG+GLGG Sbjct: 72 LFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGLGG 131 Query: 129 ALPNALALASEYSPRRYSRVIVSTLMCGMPLGAVLGGIVASILLPLHGWHSVFMVGGVLP 188 A+P + L++EYSP+R+ ++V+ G G LGG+VA+ +LP++GW V + GGV P Sbjct: 132 AMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGVTP 191 Query: 189 VAVALFAIAFMPESARFLILRNQSDRRLGAIMHRIA-PDLPREQQF--HVPLSRSTGVPI 245 + + +MPES +FL R Q L I+ RIA D F P P Sbjct: 192 LVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIAGHDHGDGVTFIGDRPAQEGAPFPG 251 Query: 246 GELFSKGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLVGAHHPVSVGIAAISFFSGGGVV 305 LFS G + TVLLW +F +L V Y + SW+P V+ ++ + GG + Sbjct: 252 RNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVPLGGTI 311 Query: 306 GCLLQGWLMNSFGVRKVLVTELVLYAVLAAVLANWPSSYATVVVVSTLMGVVIQGAQAGF 365 G + LM+ G + L+ A+ A + + A + V ++G I GAQ G Sbjct: 312 GAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIAGAQNGI 371 Query: 366 NVLATEIYPTHMRATGVGFAIGIGRIGSICGPLSGGLMLALQLDVKHIF 414 N+LA ++YPT RATGV +A+G+GR GSI G L GG ++ V+ +F Sbjct: 372 NLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQTLF 420