BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0126.p (476 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA1450 [E] COG0065 3-isopropylmalate dehydratase large subunit ... 585 e-167 NMB1036 [E] COG0065 3-isopropylmalate dehydratase large subunit ... 585 e-167 XF2375 [E] COG0065 3-isopropylmalate dehydratase large subunit X... 583 e-166 PA3121 [E] COG0065 3-isopropylmalate dehydratase large subunit P... 581 e-165 RSc1990 [E] COG0065 3-isopropylmalate dehydratase large subunit ... 579 e-165 >NMA1450 [E] COG0065 3-isopropylmalate dehydratase large subunit NmA Neisseria meningitidis Z2491 Length = 469 Score = 585 bits (1509), Expect = e-167, Method: Compositional matrix adjust. Identities = 280/464 (60%), Positives = 354/464 (76%), Gaps = 1/464 (0%) Query: 9 ALTLFEKLWQAHVVSSDDEGNALVYIDRQYVYEVTSPQAFEGLREKKRKVRRPGTVLATV 68 A TL++KLW +HVV +++G L+YIDR V+EVTSPQAFEGL+ RK+ R +V++T Sbjct: 3 AQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVSTA 62 Query: 69 DHNVPTTARDVPMRDRLAQLQVDTLTSNCADFG-IPYFDIRDVRQGIVHVVGPEQGATLP 127 DHN PT D ++D +++LQVDTL N +FG + YF D QGIVHV+GPEQGATLP Sbjct: 63 DHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGATLP 122 Query: 128 GSTVICGDSHTSTHGAFGALAWGVGTTEVEHALATHCLWLVRPLTTRITVKGTLAPGVGA 187 G TV+CGDSHTSTHGAFGALA G+GT+EVEH +AT C+ + + I V G L GV A Sbjct: 123 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLIAVDGKLKAGVTA 182 Query: 188 KDLALYLIGFLGTQGGIGHAIEFAGDAIAALSMEGRMTLCNMAVEAGARFGLVAVDDTTI 247 KD+ALY+IG +GT GG G+AIEF G+AI +LSMEGRMTLCNMA+EAGAR G+VAVD TTI Sbjct: 183 KDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQTTI 242 Query: 248 DYLQGRPLVPSGAQWDAANAYWRQLRSDSGAQFYRELEIDAGTVKPMVTWGTSPDMCVGV 307 DY++ +P P G WD A YWR L SD GA F +E +A ++P VTWGTSP+M + + Sbjct: 243 DYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLDI 302 Query: 308 DGVVPDPSQEENITRQSGMRKALAYMDISAGTPMEQLALDKVFIGSCTNARIEDLRAAAA 367 VP+P++E + ++SGM +AL YM + AGTP+ ++ +D VFIGSCTN+R+EDLR AAA Sbjct: 303 SSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRVEDLREAAA 362 Query: 368 VVRGYTVSQTIRQALVVPGSGLVKRQAEQEGLDKVFLAAGFEWREPGCSMCLGMNDDRLA 427 + + + +++ L+VPGSGLVK QAE+EGLDK+F+ AGFEWREPGCSMCL MN DRL Sbjct: 363 IAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADRLT 422 Query: 428 PGERCASTSNRNFEGRQGPGGRSHLVSPATAAAAAICGHFTDVR 471 PG+RCASTSNRNFEGRQG GGR+HLVSPA AAAAA+ G FTD+R Sbjct: 423 PGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIR 466 >NMB1036 [E] COG0065 3-isopropylmalate dehydratase large subunit Nme Neisseria meningitidis MC58 Length = 469 Score = 585 bits (1507), Expect = e-167, Method: Compositional matrix adjust. Identities = 280/464 (60%), Positives = 354/464 (76%), Gaps = 1/464 (0%) Query: 9 ALTLFEKLWQAHVVSSDDEGNALVYIDRQYVYEVTSPQAFEGLREKKRKVRRPGTVLATV 68 A TL++KLW +HVV +++G L+YIDR V+EVTSPQAFEGL+ RK+ R +V++T Sbjct: 3 AQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVSTA 62 Query: 69 DHNVPTTARDVPMRDRLAQLQVDTLTSNCADFG-IPYFDIRDVRQGIVHVVGPEQGATLP 127 DHN PT D ++D +++LQVDTL N +FG + YF D QGIVHV+GPEQGATLP Sbjct: 63 DHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGATLP 122 Query: 128 GSTVICGDSHTSTHGAFGALAWGVGTTEVEHALATHCLWLVRPLTTRITVKGTLAPGVGA 187 G TV+CGDSHTSTHGAFGALA G+GT+EVEH +AT C+ + + I+V G L GV A Sbjct: 123 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLISVDGKLKAGVTA 182 Query: 188 KDLALYLIGFLGTQGGIGHAIEFAGDAIAALSMEGRMTLCNMAVEAGARFGLVAVDDTTI 247 KD+ALY+IG +GT GG G+AIEF G+AI +LSME RMTLCNMA+EAGAR G+VAVD TTI Sbjct: 183 KDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMESRMTLCNMAIEAGARSGMVAVDQTTI 242 Query: 248 DYLQGRPLVPSGAQWDAANAYWRQLRSDSGAQFYRELEIDAGTVKPMVTWGTSPDMCVGV 307 DY++ +P P G WD A YWR L SD GA F +E +A ++P VTWGTSP+M + + Sbjct: 243 DYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLDI 302 Query: 308 DGVVPDPSQEENITRQSGMRKALAYMDISAGTPMEQLALDKVFIGSCTNARIEDLRAAAA 367 VP+P++E + ++SGM +AL YM + AGTP+ ++ +D VFIGSCTN+RIEDLR AAA Sbjct: 303 SSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREAAA 362 Query: 368 VVRGYTVSQTIRQALVVPGSGLVKRQAEQEGLDKVFLAAGFEWREPGCSMCLGMNDDRLA 427 + + + +++ L+VPGSGLVK QAE+EGLDK+F+ AGFEWREPGCSMCL MN DRL Sbjct: 363 IAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADRLT 422 Query: 428 PGERCASTSNRNFEGRQGPGGRSHLVSPATAAAAAICGHFTDVR 471 PG+RCASTSNRNFEGRQG GGR+HLVSPA AAAAA+ G FTD+R Sbjct: 423 PGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIR 466 >XF2375 [E] COG0065 3-isopropylmalate dehydratase large subunit Xfa Xylella fastidiosa 9a5c Length = 474 Score = 583 bits (1502), Expect = e-166, Method: Compositional matrix adjust. Identities = 289/469 (61%), Positives = 351/469 (74%), Gaps = 5/469 (1%) Query: 8 AALTLFEKLWQAHVVSSDDEGNALVYIDRQYVYEVTSPQAFEGLREKKRKVRRPGTVLAT 67 A TL+ KLW H V+ D+G++L+YIDR ++EVTSPQAFEGLR R + R +AT Sbjct: 2 AGKTLYSKLWDIHEVARRDDGSSLIYIDRHILHEVTSPQAFEGLRLAGRPLWRVNANIAT 61 Query: 68 VDHNVPTTARD-----VPMRDRLAQLQVDTLTSNCADFGIPYFDIRDVRQGIVHVVGPEQ 122 DHNVPTT + + + D +++LQV TL NC DFGI F + DVRQGIVHV+GPEQ Sbjct: 62 PDHNVPTTKAERQGSLLSIADTVSRLQVQTLDENCDDFGIFEFKMNDVRQGIVHVIGPEQ 121 Query: 123 GATLPGSTVICGDSHTSTHGAFGALAWGVGTTEVEHALATHCLWLVRPLTTRITVKGTLA 182 GATLPG TV+CGDSHTSTHGAFGALA G+GT+EVEH LAT CL + ++ V+GTL Sbjct: 122 GATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVTQKMKNMQVRVEGTLP 181 Query: 183 PGVGAKDLALYLIGFLGTQGGIGHAIEFAGDAIAALSMEGRMTLCNMAVEAGARFGLVAV 242 GV AKD+ L LIG +GT GG G+A+EF+G I ALSMEGRMT+CNMA+EAGAR G+VAV Sbjct: 182 WGVTAKDIVLALIGKIGTAGGNGYAVEFSGSTIRALSMEGRMTICNMAIEAGARVGMVAV 241 Query: 243 DDTTIDYLQGRPLVPSGAQWDAANAYWRQLRSDSGAQFYRELEIDAGTVKPMVTWGTSPD 302 D+ TI Y+ GRP P G+ WDAA A+WR L SD A F R +E+ A +KP VTWGTSP+ Sbjct: 242 DEKTIQYVHGRPFAPKGSDWDAAVAFWRGLVSDPDAHFDRVVELSAEEIKPQVTWGTSPE 301 Query: 303 MCVGVDGVVPDPSQEENITRQSGMRKALAYMDISAGTPMEQLALDKVFIGSCTNARIEDL 362 M VD VPDP +E + ++ + +AL YM + P+ + LD+VFIGSCTN+RIEDL Sbjct: 302 MVSAVDQSVPDPERETDPVKKESLIRALKYMGLQPNDPITSIKLDRVFIGSCTNSRIEDL 361 Query: 363 RAAAAVVRGYTVSQTIRQALVVPGSGLVKRQAEQEGLDKVFLAAGFEWREPGCSMCLGMN 422 RAAA VV+G V+ T++QA+VVPGSGLVK QAE EGLDK+F+ AGFEWREPGCSMCL MN Sbjct: 362 RAAAEVVKGRKVASTVKQAMVVPGSGLVKAQAEVEGLDKIFIEAGFEWREPGCSMCLAMN 421 Query: 423 DDRLAPGERCASTSNRNFEGRQGPGGRSHLVSPATAAAAAICGHFTDVR 471 D+L GE CASTSNRNFEGRQG GGR+HLVSPA AAAAA+ GHF DVR Sbjct: 422 PDKLGSGEHCASTSNRNFEGRQGIGGRTHLVSPAMAAAAAVAGHFVDVR 470 >PA3121 [E] COG0065 3-isopropylmalate dehydratase large subunit Pae Pseudomonas aeruginosa Length = 474 Score = 581 bits (1497), Expect = e-165, Method: Compositional matrix adjust. Identities = 291/469 (62%), Positives = 350/469 (74%), Gaps = 5/469 (1%) Query: 8 AALTLFEKLWQAHVVSSDDEGNALVYIDRQYVYEVTSPQAFEGLREKKRKVRRPGTVLAT 67 A TL++KLW H+V D+G+AL+YIDR ++EVTSPQAFEGLR RK R +AT Sbjct: 2 AGKTLYDKLWDMHLVKQRDDGSALIYIDRHILHEVTSPQAFEGLRLAGRKPWRIDANIAT 61 Query: 68 VDHNVPTTARD-----VPMRDRLAQLQVDTLTSNCADFGIPYFDIRDVRQGIVHVVGPEQ 122 DHNVPTT + + D +++LQV TL NC DFGI F + DVRQGIVHVVGPEQ Sbjct: 62 PDHNVPTTRTERKGGIAAIADEVSRLQVQTLDENCDDFGITEFKMNDVRQGIVHVVGPEQ 121 Query: 123 GATLPGSTVICGDSHTSTHGAFGALAWGVGTTEVEHALATHCLWLVRPLTTRITVKGTLA 182 GATLPG TV+CGDSHTSTHGAFGALA G+GT+EVEH LAT CL + + V+G L Sbjct: 122 GATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVKVEGRLP 181 Query: 183 PGVGAKDLALYLIGFLGTQGGIGHAIEFAGDAIAALSMEGRMTLCNMAVEAGARFGLVAV 242 GV AKD+ L +IG +GT GG GHAIEFAG AI LS+EGRMT+CNM++EAGAR GLVAV Sbjct: 182 AGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGLVAV 241 Query: 243 DDTTIDYLQGRPLVPSGAQWDAANAYWRQLRSDSGAQFYRELEIDAGTVKPMVTWGTSPD 302 D TIDY++GRP PS QWD A A W+ L SD+ A+F +E+DA +KP V+WGTSP+ Sbjct: 242 DQKTIDYVKGRPFAPSAEQWDQAVACWQGLVSDADARFDTVVELDAAQIKPQVSWGTSPE 301 Query: 303 MCVGVDGVVPDPSQEENITRQSGMRKALAYMDISAGTPMEQLALDKVFIGSCTNARIEDL 362 M + VD VPDP++E + ++ + +AL YM + + + LD+VFIGSCTN+RIEDL Sbjct: 302 MVLAVDQNVPDPARESDPIKRGSIERALKYMGLRPNQAITDIQLDRVFIGSCTNSRIEDL 361 Query: 363 RAAAAVVRGYTVSQTIRQALVVPGSGLVKRQAEQEGLDKVFLAAGFEWREPGCSMCLGMN 422 RAAA V RG V+ TI+QALVVPGSGLVK QAE+EGLD++F+ AGFEWREPGCSMCL MN Sbjct: 362 RAAAEVARGRKVAATIKQALVVPGSGLVKEQAEKEGLDRIFIEAGFEWREPGCSMCLAMN 421 Query: 423 DDRLAPGERCASTSNRNFEGRQGPGGRSHLVSPATAAAAAICGHFTDVR 471 DRL GE CASTSNRNFEGRQG GGR+HLVSPA AAAAA+ G F DVR Sbjct: 422 PDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVNGRFIDVR 470 >RSc1990 [E] COG0065 3-isopropylmalate dehydratase large subunit Rso Ralstonia solanacearum Length = 469 Score = 579 bits (1492), Expect = e-165, Method: Compositional matrix adjust. Identities = 282/465 (60%), Positives = 352/465 (75%), Gaps = 2/465 (0%) Query: 9 ALTLFEKLWQAHVVSSDDEGNALVYIDRQYVYEVTSPQAFEGLREKKRKVRRPGTVLATV 68 A TL++KLW HVV ++++G ++YIDRQ ++EVTSPQAFEGL+ R V R LA Sbjct: 2 AKTLYDKLWDDHVVHTEEDGTTVLYIDRQLLHEVTSPQAFEGLKLANRPVWRISANLAVS 61 Query: 69 DHNVPTTARDVPMRDRLAQLQVDTLTSNCADFGIPYFDIRDVRQGIVHVVGPEQGATLPG 128 DHNVPTT R + D +++LQVDTL +NC FGI F + D RQGIVHV+GPEQGATLPG Sbjct: 62 DHNVPTTDRSHGIADPVSKLQVDTLDANCDSFGITQFKMTDKRQGIVHVIGPEQGATLPG 121 Query: 129 STVICGDSHTSTHGAFGALAWGVGTTEVEHALATHCLWLVRPLTTRITVKGTLAPGVGAK 188 TV+CGDSHTSTHGAFGALA G+GT+EVEH LAT L + + V+GTL G AK Sbjct: 122 MTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAKKSKNMLVKVEGTLPRGCTAK 181 Query: 189 DLALYLIGFLGTQGGIGHAIEFAGDAIAALSMEGRMTLCNMAVEAGARFGLVAVDDTTID 248 D+ L +IG +GT GG G+A+EF G AI ALSMEGRMT+CNMA+EAGAR G+V VDD T++ Sbjct: 182 DIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMVGVDDITLE 241 Query: 249 YLQGRPLVPSGAQWDAANAYWRQLRSDSGAQFYRELEIDAGTVKPMVTWGTSPDMCVGVD 308 Y++GRP P G +W+ A AYWR L SD GA+F +E+ A ++P V+WGTSP+M V ++ Sbjct: 242 YIKGRPFAPQGVEWEQAVAYWRSLHSDEGARFDHVVELRAEEIRPQVSWGTSPEMVVSIE 301 Query: 309 GVVPDPSQEENITRQSGMRKALAYMDISAGTPMEQLALDKVFIGSCTNARIEDLRAAAAV 368 VPDP +E++ +++ M +AL YM + + + +DKVFIGSCTN+RIED+RAAA V Sbjct: 302 DRVPDPDKEKDPVKRNAMERALEYMALQPNVAIGDIRIDKVFIGSCTNSRIEDMRAAAWV 361 Query: 369 VR--GYTVSQTIRQALVVPGSGLVKRQAEQEGLDKVFLAAGFEWREPGCSMCLGMNDDRL 426 V+ G ++ ++ A+VVPGSGLVK QAE+EGLDK+F AAGFEWREPGCSMCL MN DRL Sbjct: 362 VQKLGKRIASNVKLAMVVPGSGLVKEQAEREGLDKIFKAAGFEWREPGCSMCLAMNADRL 421 Query: 427 APGERCASTSNRNFEGRQGPGGRSHLVSPATAAAAAICGHFTDVR 471 PGERCASTSNRNFEGRQG GGR+HLVSPA AAAAA+ GHF DVR Sbjct: 422 EPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAALEGHFVDVR 466