BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0108.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2091 [GEPR] COG0477 Permeases of the major facilitator superfa... 91 4e-18 BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 90 9e-18 PA2589 [GEPR] COG0477 Permeases of the major facilitator superfa... 86 1e-16 SMb20272 [GEPR] COG0477 Permeases of the major facilitator super... 83 1e-15 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 75 3e-13 >PA2091 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 427 Score = 90.9 bits (224), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 103/373 (27%), Positives = 174/373 (46%), Gaps = 7/373 (1%) Query: 28 VIFFTFAIFLKPLAADLGWSRSVLSAALLVITVMTVVVSPLIGRLVDRIGVSYVVVPSIV 87 ++ +F++F++P+AADL W R + + ++ + + SPL G LVDR G +V+P Sbjct: 44 LVISSFSLFIEPIAADLDWDRGQSALPVTLLGLAVALSSPLKGWLVDRWGARALVLPLTA 103 Query: 88 VLSLAICSLGWVTDMYGYFLVFTVIGISGVAHSPLSYSREIARRFIGNRGLALGLATAGI 147 L+L + SL G+ L + + + Y+R + F RG A G+ G Sbjct: 104 ALALCLASL--ALARSGWQLYLLFALLGLLTPGNIPYARILGGWFERRRGAAYGILGLGF 161 Query: 148 GIGGAVMPVLAQHLIANEGWRHTYQILG-GIVLIVGLGGFLVFRRGYG-VPEKQEQKGAL 205 G+GG + L I GWR T+ + G L+ + +FR G +P+ + Sbjct: 162 GVGGPLALYLGSACIDAFGWRATFLVYGLLEGLLALPLLYALFRERPGDLPQARRTPADA 221 Query: 206 TAGEEPRIKLFGSPTFWLLAGAFFLMGTGVNGTISHLSAILTDQGAATQIAAIAQSVVGI 265 G P + + S FWL+ G L V G + H +L ++G + ++A + + + Sbjct: 222 LPGATPG-QAWRSADFWLIVGNLILGVFAVTGVMVHGVPLLQERGLSREVATDVLAALWV 280 Query: 266 SMIAGRLMCGFMFDRFTPPRVAILFAVAPLIGVLVFALGAEQPGFFLVACILVGVAGGAE 325 MI + G++ DR+ PR+A+ FA+ +G+L+ LG + A L+G+ G E Sbjct: 281 GMIVSQPALGYLLDRYDTPRIALPFALLAALGLLLLLLGGPPALLW-GAVFLIGLGAGGE 339 Query: 326 ADMLAYFAALYFPMKSFSEITGYFFS-AFTLGVGIGSIGLARSFDLMGSYRGGLIASAVV 384 YF + YF ++ FS I G F + + +GS L +D GSY G + Sbjct: 340 TGTTQYFVSRYFGLRHFSVIYGSIQPFTFAIAISLGSWLLGYFYDRAGSYAGSTLVLLGA 399 Query: 385 LGALCFIFYLLGR 397 G + +LGR Sbjct: 400 FGVAAGLLVMLGR 412 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 90.1 bits (222), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 94/375 (25%), Positives = 165/375 (44%), Gaps = 15/375 (4%) Query: 32 TFAIFLKPLAADLGWSRSVLSAALLVITVMTVVVSPLIGRLVDRIGVSYVVVPSIVVLSL 91 +F F++P + R +S + ++ + PLIG+LVDR+G +++ S +++ + Sbjct: 28 SFGAFVQPWETEFSMDRGSISLISTLSFIVYGISQPLIGKLVDRLGARFILSCSTLLVGV 87 Query: 92 AICSLGWVTDMYGYFLVFTVIGISGVAH-SPLSYSREIARRFIGNRGLALGLATAGIGIG 150 + T + F+++ V+ GV S ++ + I F RGLA G+ AG G G Sbjct: 88 SFVLTTMATQPWHLFILYGVVVSIGVGGASNVAATVVITNWFNKKRGLAFGIIEAGFGAG 147 Query: 151 GAVMPVLAQHLIANEGWRHTYQILGGIVLIVGLGGFLVFRRGY----------GVPEKQE 200 ++ + LI W+ T ILG + ++ L+ R + GV E++E Sbjct: 148 QMILVPGSLMLIQWLDWKATVVILGFFLAVIVFPIVLLLLRNHPSEKQVEPIGGVREEEE 207 Query: 201 QKGALTAGEEPRIKLFGSPTFWLLAGAFFLMGTGVNGTI-SHLSAILTDQGAATQIAAIA 259 + + +F FW L F + G G + +HL + D G +T + + A Sbjct: 208 TNTSPNSATFSNWSVFRMRPFWFLVLPFAICGFTTTGLMDTHLIPLSHDHGFSTSVTSAA 267 Query: 260 QSVVGISMIAGRLMCGFMFDRFTPPRVAILFAVAPLIGVLVFALGAEQPGFFLVACILVG 319 S++ I G L+ G + DR++ + L VA + LV + + P L IL G Sbjct: 268 VSLLAGFNIVGILLSGVIADRWSSRKFLFLLYVARALS-LVILVHSHDPLLLLGFAILFG 326 Query: 320 VAGGAEADMLAYFAALYFPMKSFSEITGYFFSAFTLGVGIGSIGLARSFDLMGSYRGGLI 379 + A A YF S + G+ F + +G +G+ ++ GSY L Sbjct: 327 LVDFATVAPTQLLATQYFKRYSIGLMIGWLFLSHQVGSALGAYVPGLLYEQTGSYTVSLY 386 Query: 380 ASAVVL--GALCFIF 392 S V+L A+C +F Sbjct: 387 VSIVILIVAAICNLF 401 >PA2589 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 404 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 96/355 (27%), Positives = 170/355 (47%), Gaps = 15/355 (4%) Query: 28 VIFFTFAIFLKPLAADLGWSRSVLSAALLVITVMTVVVSPLIGRLVDRIGVSYVVVPSIV 87 ++ TF++F+ P++A+ W R+ +S + + + + SPL G L+DR G ++ Sbjct: 28 ILLNTFSLFIAPMSAEYAWDRAEVSLLVTLFGLAVAITSPLKGWLIDRWGARRTMLGLTA 87 Query: 88 VLSLAICSLGWVTDMYGYFLVFTVIGISGVAHSPLSYSREIARRFIGNRGLALGLATAGI 147 LSL + L V ++ + +F +IG+ +A L Y R + F G+A GL G Sbjct: 88 ALSLPLLGLAAVNAVWQLYALFLLIGL--LAPGNLPYGRILGLWFRQRLGVAYGLLGLGF 145 Query: 148 GIGGAVMPVLAQHLIANEGWRHTYQILG-GIVLIVGLGGFLVFRRGYGVPEKQEQ----- 201 G+GG + ++ + GWR + + G + + +FR P+ Sbjct: 146 GVGGPLGLLVGHQSLEAWGWRGAFLVYGVLELGLALPLLAWLFREP--APDAGVAAGTAV 203 Query: 202 -KGALTAGEEPRIKLFGSPTFWLLAGAFFLMGTGVNGTISHLSAILTDQGAATQIAAIAQ 260 + AL+ P + + S +FWL+ G L ++G ++H +L ++G + A A Sbjct: 204 AETALSGSTAP--QAWRSASFWLVLGNQVLAVFVMSGIMTHGVPMLVERGLSRGEAGTAL 261 Query: 261 SVVGISMIAGRLMCGFMFDRFTPPRVAILFAVAPLIGVLVFALGAEQPGFFLVACILVGV 320 S + + M+ + + G++ DR PRVA+ FA+A ++G+ F +G G +L A LVG+ Sbjct: 262 SALWVGMMLSQPLMGWLLDRVATPRVALPFALAAVLGMAWFLVGDTPSGLWL-AVFLVGL 320 Query: 321 AGGAEADMLAYFAALYFPMKSFSEITGYFFS-AFTLGVGIGSIGLARSFDLMGSY 374 GG E+ Y YF ++SF I G F L + +G+ L +D Y Sbjct: 321 GGGGESGTTKYLLMRYFGLRSFGVIYGSIQPFTFALSISLGAYLLGWLYDRAEGY 375 >SMb20272 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 402 Score = 83.2 bits (204), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 90/350 (25%), Positives = 155/350 (44%), Gaps = 13/350 (3%) Query: 31 FTFAIFLKPLAADLGWSRSVLSAALLVITVMTVVVSPLIGRLVDRIGVSYVVVPSIVVLS 90 F+ +FL P++ D GWS + +S+A+ V + + S + G DR G VV+ +L+ Sbjct: 26 FSLPVFLVPISRDTGWSVTGISSAMTVGFIAMALASMVWGSASDRWGPRSVVLIGSALLA 85 Query: 91 LAICSLGWVTDMYGYFLVFTVI--GISGVAHSPLSYSREIARRFIGNRGLALGLATAGIG 148 ++ VT + + LVF V+ G +P+ + F +R LA+ L +AG+G Sbjct: 86 ASLALSSLVTSLIAFQLVFGVVVGGACAAIFAPMMAC--VTGWFDTHRSLAVSLVSAGMG 143 Query: 149 IGGAVMPVLAQHLIANEGWRHTYQILGGIVLIVGLGGFLVFRRGYGVPEKQEQKGALTAG 208 + M LA L+ WR + QI+ + + + L+ RR P E A++A Sbjct: 144 MAPMTMSPLAGWLVTIYDWRTSLQIIAALAAVTMIPAALLLRR----PPVLEDTNAVSAS 199 Query: 209 E-EPRIKL---FGSPTFWLLAGAFFLMGTGVNGTISHLSAILTDQGAATQIAAIAQSVVG 264 E +P + L SP F +L F +G I H + G A S+ G Sbjct: 200 EGQPDMSLGQALRSPQFVILLLTNFFCCATHSGPIFHTVSYAVSCGIPMMAAVSIYSLEG 259 Query: 265 ISMIAGRLMCGFMFDRFTPPRVAILFAVAPLIGVLVFALGAEQPGFFLVACILVGVAGGA 324 ++ + GR+ G + DR+ R+ + + G L + + F+ VA + + G Sbjct: 260 LAGMGGRVAFGVLGDRYGAKRILVSGLLLQAFGALAYFFVRDLGAFYAVAAVFGFIYAGV 319 Query: 325 EADMLAYFAALYFPMKSFSEITGYFFSAFTLGVGIGSIGLARSFDLMGSY 374 + A A FP++ + G A +LG+ IG + +D+ SY Sbjct: 320 M-PLYAVIARENFPLRMMGTVIGGTAMAGSLGMAIGPVAGGLIYDVFASY 368 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 75.1 bits (183), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 104/380 (27%), Positives = 171/380 (45%), Gaps = 38/380 (10%) Query: 32 TFAIFLKPLAADLGWSRSVLSAALLVITVMTVVVSPLIGRLVDRIGVSYVVVPSIVVLSL 91 +F F++P RS +S V ++ + P+IGRLVD+ G V+ S ++ + Sbjct: 27 SFGAFVEPWERQFSIDRSTISLISTVSFIVYGISQPVIGRLVDKWGARAVLAWSALLTGV 86 Query: 92 AICSLGWVTDMYGYFLVFTVIGISGVAH-SPLSYSREIARRFIGNRGLALGLATAGIGIG 150 +I VT + FL++ + GV S ++ S + F RGLA G+ AG G G Sbjct: 87 SIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVAASVLVVNWFSKKRGLAFGIMEAGFGAG 146 Query: 151 GAVMPVLAQHLIANEGWRHTYQILGGIVLIVGLGGFLVFRRGYGVPEKQEQKGALTAGEE 210 ++ + LI W+ T +LG +++++ L+ R + E G L A E+ Sbjct: 147 QMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPAALLMLRNNPSEKNTEPIGGLAASEK 206 Query: 211 ---PRIK------LFGSPTFWLLAGAFFLMG-TGVNGTISHLSAILTDQGAATQIAAIAQ 260 P+ +F FW L F + G T V +HL D G +T + + A Sbjct: 207 ETAPKTTALSVAGMFRMRQFWFLIFPFLICGFTTVGLMDTHLIPFSHDHGFSTTVTSAAV 266 Query: 261 SVVGISMIAGRLMCGFMFDRFTPPRV-AILFAVAPL-IGVLVFALGAEQPGFFLVACILV 318 S++ IAG L+ G + DR++ ++ IL+AV L I +L++ + +P L IL Sbjct: 267 SLLAGFNIAGILLSGIVADRWSSRKILCILYAVRALSIVILIY---SHEPYLLLAFAILF 323 Query: 319 GV---AGGAEADMLAYFAALYFPMKSFSEITGYFFSAFTLGVGIGSIGLARSF-DLMGSY 374 G+ A A MLA +F +++G+ IG + LA +G+Y Sbjct: 324 GLVDFATVAPTQMLA----------------TQYFQNYSIGLMIGWLSLAHQIGSALGAY 367 Query: 375 RGGLIASAVVLGALCFIFYL 394 G+I + V G FYL Sbjct: 368 VPGVIYT--VTGEYTLAFYL 385