BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0098.p (493 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0229 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 439 e-123 CC2397 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 419 e-117 VNG2513G [C] COG1012 NAD-dependent aldehyde dehydrogenases Hbs H... 360 4e-99 PA4899 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 357 3e-98 BH2010 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 345 2e-94 >RSp0229 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 492 Score = 439 bits (1129), Expect = e-123, Method: Compositional matrix adjust. Identities = 238/484 (49%), Positives = 313/484 (64%), Gaps = 3/484 (0%) Query: 12 FLEPRAWEGCFYDGKWRPASNR--FESCSPSTGKLLAHLGTTSKSELAQAIAVAGKAQLN 69 FL+ W+G + G+W P R + P+TG+ L +G ++ A+ A AQ Sbjct: 9 FLDDAQWDGLLFQGRWVPPLRRRTADVMEPATGRKLTRVGLADAQDVDAAVEAAAAAQPA 68 Query: 70 WARQPIAARAEVMRRAAELLALHSEELAGWLVREGGSIRPKAAFEIQSAVDELHHAAGLI 129 W P RA V RRAA L H +ELA + RE G+ K E++ A+ H AAG+ Sbjct: 69 WVAMPPRERANVFRRAAMLFEQHFDELALAIARETGAALFKGEHEVREAITLCHVAAGMP 128 Query: 130 THSEGQVISSPDPDRLSFSRRLPIGIVGVITPWNVPLLLAMRSVAPALVLGNAVVLKPDP 189 ++GQV++SP RLS++RR P G+VGVI+P+N PL L +RSVAPAL GNAVV+KPD Sbjct: 129 LEAQGQVLASP-AGRLSYARRAPFGVVGVISPFNFPLFLTLRSVAPALAAGNAVVIKPDL 187 Query: 190 HTSVSGGIALARLFEMAGLPEGVFCMTPGGAEVGEALVEAPGVRMITFTGSTHVGRRVGE 249 T VSGG +AR+F AGLP G+ + PGGAE GEALV P V MI FTGS VGRR+GE Sbjct: 188 RTPVSGGYVIARVFAEAGLPAGLLHVLPGGAEAGEALVVHPRVPMIAFTGSPGVGRRIGE 247 Query: 250 LAGRNLKRVALELGGNSPMLVLDDCDIKKAVAAGAFGSFHHQGQICMATSRHIVSRAIAD 309 LAGR+LK+V+LELGG + +++LDD D+ AV+ A+G++ HQGQICMA +R +V ++AD Sbjct: 248 LAGRHLKKVSLELGGANALIILDDADLDLAVSNAAWGAWLHQGQICMAANRILVHASLAD 307 Query: 310 QYVELLVQKARSLAVGDPELSDVALGPLINSRQRDRAHDIVTRSIAAGAEIATGGKYNAL 369 LV+KA L VGD VALGPLI+ +Q R H IV S+AAGA + GG Y L Sbjct: 308 ALTARLVEKAEHLPVGDGASGQVALGPLIDQKQLQRVHAIVQDSVAAGARLLAGGSYEQL 367 Query: 370 FYEPTVLTGVTPGMAAFDDEIFAPVAPIIVAEDDEHALELAAATPYGLAAAIQTGDIGRG 429 FY PTVL GV PGM FD+E+F PVA IIV DD+ A+ LA + GLAA + + +GR Sbjct: 368 FYRPTVLAGVRPGMRVFDEEVFGPVANIIVFRDDDEAVALANDSQGGLAAGVISASVGRA 427 Query: 430 LRLARRLRVGMIHINDQTIVDLPQAPMGGMGQSGNGSRFGSLSSWEDFTEWQWLTASSSP 489 + L +RLRVGM+HINDQT+ D P GG G +GNG+ G + WE++T+W+W+T S Sbjct: 428 MALGQRLRVGMVHINDQTVNDDCVNPFGGPGIAGNGTSMGGPADWEEYTQWRWVTVKESA 487 Query: 490 ALYP 493 YP Sbjct: 488 PRYP 491 >CC2397 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 487 Score = 419 bits (1078), Expect = e-117, Method: Compositional matrix adjust. Identities = 226/483 (46%), Positives = 311/483 (64%), Gaps = 2/483 (0%) Query: 12 FLEPRAW-EGCFYDGKWRPASNRFESCSPSTGKLLAHLGTTSKSELAQAIAVAGKAQLNW 70 L AW + F DG +P+ P+T +L +G +S++A+A A A AQ W Sbjct: 5 LLSADAWTDRLFSDGWVKPSGGVIAVQEPATETVLTQVGRADRSDVARAAASAKAAQPAW 64 Query: 71 ARQPIAARAEVMRRAAELLALHSEELAGWLVREGGSIRPKAAFEIQSAVDELHHAAGLIT 130 A AR ++ RAA+LL H+ +LA W++RE GS+ KAA E++ A + A + T Sbjct: 65 AALTADARQAILLRAADLLVEHAPDLAPWIMRESGSVAAKAAVELEHAAGFVRQAGAMAT 124 Query: 131 HSEGQVISSPDPDRLSFSRRLPIGIVGVITPWNVPLLLAMRSVAPALVLGNAVVLKPDPH 190 + G V+ S P + S +RR+P+G+V VI+P+N PL+L++R+VAPAL GNAVVLKPDP Sbjct: 125 EAAGLVLPS-SPGKTSIARRVPLGVVAVISPFNFPLVLSIRAVAPALATGNAVVLKPDPR 183 Query: 191 TSVSGGIALARLFEMAGLPEGVFCMTPGGAEVGEALVEAPGVRMITFTGSTHVGRRVGEL 250 T +SGG +AR+FE AGLP G+ + PG AE G+AL P + M+ FTGST GR+VGE+ Sbjct: 184 TPISGGFLIARVFEAAGLPAGLLHVLPGDAEAGDALCRDPNIAMVAFTGSTGAGRKVGEV 243 Query: 251 AGRNLKRVALELGGNSPMLVLDDCDIKKAVAAGAFGSFHHQGQICMATSRHIVSRAIADQ 310 AG +LK+VALELGG +P+++LDD D A + A+G++ HQGQ+CM R +V R I D Sbjct: 244 AGAHLKKVALELGGKNPLIILDDADPDVAASNAAWGAWLHQGQVCMTAGRLLVQRGIHDA 303 Query: 311 YVELLVQKARSLAVGDPELSDVALGPLINSRQRDRAHDIVTRSIAAGAEIATGGKYNALF 370 VE L KA L VGDP DVALGPLI+ Q DR H IV+ ++A GA + GG + L Sbjct: 304 VVERLAAKAGHLPVGDPMRGDVALGPLISRGQLDRVHAIVSDTVADGARLVAGGTHKGLC 363 Query: 371 YEPTVLTGVTPGMAAFDDEIFAPVAPIIVAEDDEHALELAAATPYGLAAAIQTGDIGRGL 430 Y PTVLTGV PGM AF++EIF P+A + V +D + A LA PYGL+A I +G +GR + Sbjct: 364 YAPTVLTGVAPGMRAFEEEIFGPIAAVTVFDDLDEAARLANDGPYGLSAGIISGSVGRAM 423 Query: 431 RLARRLRVGMIHINDQTIVDLPQAPMGGMGQSGNGSRFGSLSSWEDFTEWQWLTASSSPA 490 L +L VG +HINDQT+ P +P GGM SGNG+R ++ ++FT W+W T ++ Sbjct: 424 TLGAKLEVGHLHINDQTVDAGPHSPFGGMKASGNGTRISGPANLDEFTTWRWETVKAAAT 483 Query: 491 LYP 493 YP Sbjct: 484 AYP 486 >VNG2513G [C] COG1012 NAD-dependent aldehyde dehydrogenases Hbs Halobacterium sp. NRC-1 Length = 489 Score = 360 bits (924), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 194/479 (40%), Positives = 283/479 (59%), Gaps = 4/479 (0%) Query: 18 WEGCFYDGKWRPASNR--FESCSPSTGKLLAHLGTTSKSELAQAIAVAGKAQLNWARQPI 75 W + DG++ P +R E PST +L + + ++ A A AQ WA P Sbjct: 11 WNVQYIDGEYVPPGDRGTLEVDDPSTRELFTEIPAGTTDDVDAAYEAAADAQTEWADTPP 70 Query: 76 AARAEVMRRAAELLALHSEELAGWLVREGGSIRPKAAFEIQSAVDELHHAAGLITHSEGQ 135 RA ++ A+E+LA H +E+ L E G+ K A E +++V AA T G Sbjct: 71 QERARIVAAASEILASHRDEVVDLLATESGTTYTKGAAEFEASVGITDEAASFPTRMNGD 130 Query: 136 VISSPDPDRLSFSRRLPIGIVGVITPWNVPLLLAMRSVAPALVLGNAVVLKPDPHTSVSG 195 S + + R P G+VG+I+PWN PL L++R+VAPA+ GN+VVLKP +T V+G Sbjct: 131 HKQSVVEGKENIVVREPQGVVGIISPWNFPLNLSIRAVAPAVAAGNSVVLKPASNTPVTG 190 Query: 196 GIALARLFEMAGLPEGVFCMTPG-GAEVGEALVEAPGVRMITFTGSTHVGRRVGELAGRN 254 G+ +A++FE AGLPEGVF + G G+E+G+ + P +I+FTGST +GR+V AG N Sbjct: 191 GLLIAKVFEAAGLPEGVFNVVTGKGSEIGDRIAGHPHADVISFTGSTAIGRQVAATAGEN 250 Query: 255 LKRVALELGGNSPMLVLDDCDIKKAVAAGAFGSFHHQGQICMATSRHIVSRAIADQYVEL 314 L A+ELGGN+ +V +D D+ AV +G FGSF H GQIC++ +RH+V + D+YVE Sbjct: 251 LALPAMELGGNNVHIVTEDADLDDAVDSGVFGSFLHSGQICISINRHVVHEDVYDEYVER 310 Query: 315 LVQKARSLAVGDPELSDVALGPLINSRQRDRAHDIVTRSIAAGAEIATGGKYNALFYEPT 374 L ++A +L G +D +GP+I+ QRD+ D + R++ AGA + TGG ++ L EPT Sbjct: 311 LTERAAALPTGTAHDADTVVGPIIDESQRDQILDYIERTVDAGATLETGGDHDGLVVEPT 370 Query: 375 VLTGVTPGMAAFDDEIFAPVAPIIVAEDDEHALELAAATPYGLAAAIQTGDIGRGLRLAR 434 VL+ T MAA +E F PVAP+I DD+ A+E+A +T YGL+ ++ GD GR +A Sbjct: 371 VLSDATNDMAAACNEHFGPVAPVIPFSDDDEAVEIANSTEYGLSGSVHAGDTGRARDIAD 430 Query: 435 RLRVGMIHINDQTIVDLPQAPMGGMGQSGNGSRFGSLSSWEDFTEWQWLTASSSPALYP 493 R+ GMIHINDQ + P P GG SG G R+ +FT+ +W++ YP Sbjct: 431 RIDTGMIHINDQPVNQEPHLPFGGYKNSGLG-RYNGEYVLNEFTQEKWVSIQRETRDYP 488 >PA4899 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 489 Score = 357 bits (916), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 203/474 (42%), Positives = 281/474 (59%), Gaps = 6/474 (1%) Query: 25 GKWRP--ASNRFESCSPSTGKLLAHLGTTSKSELAQAIAVAGKAQLNWARQPIAARAEVM 82 G+WR A R + +P G LL + + +L A A A + Q WA +ARA V+ Sbjct: 16 GEWRHGRAGRRLKVSNPFDGSLLLEIEQADRDDLDAAYAKAAEVQPAWAALGPSARAAVL 75 Query: 83 RRAAELLALHSEELAGWLVREGGSIRPKAAFEIQSAVDELHHAAGLITHSEGQVISSPDP 142 +A E+ EE+ W++RE GS R KA E +A +A G+++ S P Sbjct: 76 YKAVEVFDRRHEEIVDWIIRESGSTRLKAEIEWGAARAITLESASFPARVHGRIVESDVP 135 Query: 143 DRLSFSRRLPIGIVGVITPWNVPLLLAMRSVAPALVLGNAVVLKPDPHTSVSGGIALARL 202 + S R IG+VGVI+PWN PL L RS+APAL LGNAVV+KP T V GG+ LAR+ Sbjct: 136 GKESRVYRSAIGVVGVISPWNFPLHLTQRSIAPALALGNAVVVKPASDTPVCGGLLLARI 195 Query: 203 FEMAGLPEGVFCMTPG-GAEVGEALVEAPGVRMITFTGSTHVGRRVGELA--GRNLKRVA 259 FE AGLP G+F + G G+E+G+A VE P ++TFTGST VGR +G +A G +LK VA Sbjct: 196 FEEAGLPAGLFSVVVGPGSEIGDAFVEHPVPGLVTFTGSTPVGRNIGRIASGGAHLKHVA 255 Query: 260 LELGGNSPMLVLDDCDIKKAVAAGAFGSFHHQGQICMATSRHIVSRAIADQYVELLVQKA 319 LELGGNSP +VL D D+++AV A FG F HQGQICMA +R IV ++ D + V++ Sbjct: 256 LELGGNSPFVVLGDADLEQAVNAAVFGKFLHQGQICMAINRIIVEDSLYDAFAARFVERV 315 Query: 320 RSLAVGDPELSDVALGPLINSRQRDRAHDIVTRSIAAGAEIATGGKYNALFYEPTVLTGV 379 + L VGDP+ +D A+GP++N+RQ + + + + GA+ G + P V V Sbjct: 316 KGLRVGDPQRADTAVGPIVNARQLEGLLEKIRLARQEGAKPLYEGGVDGQLLAPHVFGEV 375 Query: 380 TPGMAAFDDEIFAPVAPIIVAEDDEHALELAAATPYGLAAAIQTGDIGRGLRLARRLRVG 439 T M DEIF P+ ++ A D+ HALELA A+ YGL++A+ + D+ R +R AR+LR G Sbjct: 376 TATMEIARDEIFGPLVGLLRARDEAHALELANASEYGLSSAVFSRDLERAVRFARQLRAG 435 Query: 440 MIHINDQTIVDLPQAPMGGMGQSGNGSRFGSLSSWEDFTEWQWLTASSSPALYP 493 M H+ND + D AP GG SG G RF + E+FT W++ +P YP Sbjct: 436 MTHVNDIPVNDEANAPFGGEKNSGLG-RFNGDWAIEEFTTDHWISVQHAPRQYP 488 >BH2010 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 485 Score = 345 bits (885), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 194/475 (40%), Positives = 275/475 (57%), Gaps = 4/475 (0%) Query: 22 FYDGKWRP--ASNRFESCSPSTGKLLAHLGTTSKSELAQAIAVAGKAQLNWARQPIAARA 79 F G+W ++ + +P TG+ + + S +L QA A AQ W + A + Sbjct: 9 FLAGEWIEGASTQTITNYNPYTGEKIHEIKGASLDDLDQAYRAAKNAQKEWEQTLPAQKQ 68 Query: 80 EVMRRAAELLALHSEELAGWLVREGGSIRPKAAFEIQSAVDELHHAAGLITHSEGQVISS 139 EV+ +AA LLA +E+ LV E GS KA+ E + + + AA EG+++ S Sbjct: 69 EVLEKAAALLAERKDEVIERLVNEAGSSIIKASIEWGATLQTIKVAATFPLRMEGKILPS 128 Query: 140 PDPDRLSFSRRLPIGIVGVITPWNVPLLLAMRSVAPALVLGNAVVLKPDPHTSVSGGIAL 199 P + + R G++GVI+P+N PL+LAMRSVAPAL GNAVVLK ++ G+ + Sbjct: 129 NIPGKENRIYRSAKGVIGVISPFNFPLVLAMRSVAPALATGNAVVLKCSSDAPITSGLLI 188 Query: 200 ARLFEMAGLPEGVFCMTPG-GAEVGEALVEAPGVRMITFTGSTHVGRRVGELAGRNLKRV 258 A LFE AGLP+GV + G AE+G+A V P ++I+FTGST VGR + +LA R LK Sbjct: 189 AELFEEAGLPKGVLNVVVGKAAEIGDAFVTHPIPKLISFTGSTEVGRHIAQLAARELKET 248 Query: 259 ALELGGNSPMLVLDDCDIKKAVAAGAFGSFHHQGQICMATSRHIVSRAIADQYVELLVQK 318 ALELGGN+ M+VLDD DI+KA A G F HQGQICMA +R IV +I D +VE+ +K Sbjct: 249 ALELGGNNVMIVLDDADIEKAAEKAAVGKFLHQGQICMALNRIIVDASIYDSFVEVFKEK 308 Query: 319 ARSLAVGDPELSDVALGPLINSRQRDRAHDIVTRSIAAGAEIATGGKYNALFYEPTVLTG 378 L G+P +GPLIN +Q R +V S+A GA G PT+L+ Sbjct: 309 VSQLQTGNPAEPATLIGPLINYKQIGRIQQLVKESVAQGAVKVLEGHVQGNLMSPTILSE 368 Query: 379 VTPGMAAFDDEIFAPVAPIIVAEDDEHALELAAATPYGLAAAIQTGDIGRGLRLARRLRV 438 VT M +EIF P+APII A+D+ A+ +A +PYGL+ +I TG + RG+++A+++ Sbjct: 369 VTNDMPVAKEEIFGPIAPIIKAKDEAEAIAIANDSPYGLSGSIFTGSLHRGVQVAKQIDT 428 Query: 439 GMIHINDQTIVDLPQAPMGGMGQSGNGSRFGSLSSWEDFTEWQWLTASSSPALYP 493 GMIH+NDQ + + GG SG G RFG + FT +W++ +YP Sbjct: 429 GMIHVNDQPVNEEAHISFGGEKDSGIG-RFGGEWVLDKFTTVKWISIQEKERVYP 482