BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0091.p (556 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mhpA [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and r... 386 e-107 ZmhpA [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and ... 383 e-106 ECs0402 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase an... 383 e-106 Cgl1132 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase an... 182 2e-45 STM1546 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase an... 126 1e-28 >mhpA [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Eco Escherichia coli K12 Length = 554 Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust. Identities = 210/535 (39%), Positives = 305/535 (57%), Gaps = 15/535 (2%) Query: 20 VLVIGAGPTGLTLANILGQGGVRTVVIDRKESTVGEPRAVSIDDESLRTMQAIDLVKDVL 79 V + GAGP GL +AN LGQ G+ +V+++ + + PRA+ IDDE+LRTMQ++ LV DVL Sbjct: 18 VAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVL 77 Query: 80 KNVVTGYGVHYLTKPGGRCFAKVEPTASEYGYPRRNAFRQPLFEATLREGLDRFPSVTTH 139 + + + +LT P GRCFA ++P E+G+PRRNAF QP +A + EG+ RFP+V Sbjct: 78 PHTTPWHAMRFLT-PKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCL 136 Query: 140 FGHTLQSFVQHEDGVIATVIKADGSTACIHADYLVGTDGGRSTVRELLNVPMSGSTFKSR 199 F L++F Q +D V + A+G + A +LV DGG S VR LNVP G T ++ Sbjct: 137 FSRELEAFSQQDDEVTLHLKTAEGQREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQ 196 Query: 200 WLVIDTENDDDTFWQTRVYCDAKRPVVDVPGPHHTRRYEILIHPHEDAEHAMTPERVTEL 259 W+V+D ND + + CD RP V PH RR+E ++ P E E P+ + +L Sbjct: 197 WIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKL 256 Query: 260 L-RPFRNGRPTDIVRKVVYTFHARMADKWRENRVFLAGDAAHLTPPYAGQGLNSGIRDAH 318 L + N +++R+ VYT +AR+A ++R +RV LAGDAAH+ P + GQG NSG+RDA Sbjct: 257 LSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAF 316 Query: 319 NLGWKLVALHNGILTNLALDSYETERRPHAWSLIKLALNLGFVMAPKTRLHAWIAQTFFT 378 NL WKL + G + LD+Y+ ERR HA ++I L++ G V+AP R + Sbjct: 317 NLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSW 376 Query: 379 LSAYVPPVRDYFLQMKFKPKPQYANGLLGPDLTSGMR--GHMFSQPTVLLTDGRETLLDD 436 L Y+PPV+ YFL+M+FKP PQY G L + + G MF QP V L +G TLLD+ Sbjct: 377 LLNYLPPVKRYFLEMRFKPMPQYYGGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDN 436 Query: 437 VIGHRFALISYGSVPTL-----KHPLWRTTNAIRIAILPSGSDAQASEKTDSVI-VIDKN 490 IG FA+I +G P + WR I ++P A + D V+ V D Sbjct: 437 AIGANFAVIGWGCNPLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQ 496 Query: 491 DRLRTFFEKNKDHIAFLRPDRYVAGLFTSSTEEIFADDFSATL-----DSGVTVE 540 RLR++F ++ + +RPDR+VA T + ++ + D+ V+VE Sbjct: 497 GRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVE 551 >ZmhpA [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases EcZ Escherichia coli O157:H7 EDL933 Length = 554 Score = 383 bits (984), Expect = e-106, Method: Compositional matrix adjust. Identities = 209/535 (39%), Positives = 305/535 (57%), Gaps = 15/535 (2%) Query: 20 VLVIGAGPTGLTLANILGQGGVRTVVIDRKESTVGEPRAVSIDDESLRTMQAIDLVKDVL 79 V + GAGP GL +AN LGQ G+ +V+++ + + PRA+ IDDE+LRTMQ++ LV +VL Sbjct: 18 VAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVL 77 Query: 80 KNVVTGYGVHYLTKPGGRCFAKVEPTASEYGYPRRNAFRQPLFEATLREGLDRFPSVTTH 139 + + + +LT P GRCFA ++P E+G+PRRNAF QP +A + EG+ RFP+V Sbjct: 78 PHTTPWHAMRFLT-PKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCL 136 Query: 140 FGHTLQSFVQHEDGVIATVIKADGSTACIHADYLVGTDGGRSTVRELLNVPMSGSTFKSR 199 F L++F Q +D V + A+G + A +LV DGG S VR LNVP G T ++ Sbjct: 137 FSRELEAFSQQDDEVTLHLKTAEGLREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQ 196 Query: 200 WLVIDTENDDDTFWQTRVYCDAKRPVVDVPGPHHTRRYEILIHPHEDAEHAMTPERVTEL 259 W+V+D ND + + CD RP V PH RR+E ++ P E E P+ + +L Sbjct: 197 WIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKL 256 Query: 260 L-RPFRNGRPTDIVRKVVYTFHARMADKWRENRVFLAGDAAHLTPPYAGQGLNSGIRDAH 318 L + N +++R+ VYT +AR+A ++R +RV LAGDAAH+ P + GQG NSG+RDA Sbjct: 257 LSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAF 316 Query: 319 NLGWKLVALHNGILTNLALDSYETERRPHAWSLIKLALNLGFVMAPKTRLHAWIAQTFFT 378 NL WKL + G + LD+Y+ ERR HA ++I L++ G V+AP R + Sbjct: 317 NLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSW 376 Query: 379 LSAYVPPVRDYFLQMKFKPKPQYANGLL--GPDLTSGMRGHMFSQPTVLLTDGRETLLDD 436 L Y+PPV+ YFL+M+FKP PQY G L + G MF QP V L +G TLLD+ Sbjct: 377 LLNYLPPVKRYFLEMRFKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDN 436 Query: 437 VIGHRFALISYGSVPTL-----KHPLWRTTNAIRIAILPSGSDAQASEKTDSVI-VIDKN 490 IG FA+I +G P + WR + I ++P A + D V+ V D Sbjct: 437 AIGANFAVIGWGCNPLWGMSDEQIQQWRALSTRFIQVVPEVQIHTAQDNHDGVLRVGDTQ 496 Query: 491 DRLRTFFEKNKDHIAFLRPDRYVAGLFTSSTEEIFADDFSATL-----DSGVTVE 540 RLR++F ++ + +RPDR+VA T + ++ + D+ V+VE Sbjct: 497 GRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVE 551 >ECs0402 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Ecs Escherichia coli O157:H7 Length = 554 Score = 383 bits (984), Expect = e-106, Method: Compositional matrix adjust. Identities = 209/535 (39%), Positives = 305/535 (57%), Gaps = 15/535 (2%) Query: 20 VLVIGAGPTGLTLANILGQGGVRTVVIDRKESTVGEPRAVSIDDESLRTMQAIDLVKDVL 79 V + GAGP GL +AN LGQ G+ +V+++ + + PRA+ IDDE+LRTMQ++ LV +VL Sbjct: 18 VAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVL 77 Query: 80 KNVVTGYGVHYLTKPGGRCFAKVEPTASEYGYPRRNAFRQPLFEATLREGLDRFPSVTTH 139 + + + +LT P GRCFA ++P E+G+PRRNAF QP +A + EG+ RFP+V Sbjct: 78 PHTTPWHAMRFLT-PKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCL 136 Query: 140 FGHTLQSFVQHEDGVIATVIKADGSTACIHADYLVGTDGGRSTVRELLNVPMSGSTFKSR 199 F L++F Q +D V + A+G + A +LV DGG S VR LNVP G T ++ Sbjct: 137 FSRELEAFSQQDDEVTLHLKTAEGLREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQ 196 Query: 200 WLVIDTENDDDTFWQTRVYCDAKRPVVDVPGPHHTRRYEILIHPHEDAEHAMTPERVTEL 259 W+V+D ND + + CD RP V PH RR+E ++ P E E P+ + +L Sbjct: 197 WIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKL 256 Query: 260 L-RPFRNGRPTDIVRKVVYTFHARMADKWRENRVFLAGDAAHLTPPYAGQGLNSGIRDAH 318 L + N +++R+ VYT +AR+A ++R +RV LAGDAAH+ P + GQG NSG+RDA Sbjct: 257 LSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAF 316 Query: 319 NLGWKLVALHNGILTNLALDSYETERRPHAWSLIKLALNLGFVMAPKTRLHAWIAQTFFT 378 NL WKL + G + LD+Y+ ERR HA ++I L++ G V+AP R + Sbjct: 317 NLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSW 376 Query: 379 LSAYVPPVRDYFLQMKFKPKPQYANGLL--GPDLTSGMRGHMFSQPTVLLTDGRETLLDD 436 L Y+PPV+ YFL+M+FKP PQY G L + G MF QP V L +G TLLD+ Sbjct: 377 LLNYLPPVKRYFLEMRFKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDN 436 Query: 437 VIGHRFALISYGSVPTL-----KHPLWRTTNAIRIAILPSGSDAQASEKTDSVI-VIDKN 490 IG FA+I +G P + WR + I ++P A + D V+ V D Sbjct: 437 AIGANFAVIGWGCNPLWGMSDEQIQQWRALSTRFIQVVPEVQIHTAQDNHDGVLRVGDTQ 496 Query: 491 DRLRTFFEKNKDHIAFLRPDRYVAGLFTSSTEEIFADDFSATL-----DSGVTVE 540 RLR++F ++ + +RPDR+VA T + ++ + D+ V+VE Sbjct: 497 GRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVE 551 >Cgl1132 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Cgl Corynebacterium glutamicum Length = 530 Score = 182 bits (462), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 147/519 (28%), Positives = 228/519 (43%), Gaps = 34/519 (6%) Query: 11 MNIETIKTAVLVIGAGPTGLTLANILGQGGVRTVVIDRKESTVGEPRAVSIDDESLRTMQ 70 M+ T V ++G GPTG LA +LGQ G R ++++ + PRAV+ D E R + Sbjct: 1 MSPNNFDTDVCIVGGGPTGTLLAVLLGQKGHRVTILEKWPTFYERPRAVTFDHEIARILG 60 Query: 71 AIDLVKDVLKNVVTGYGVHYLTKPGGRCFAKVEPTA-SEYGYPRRNAFRQPLFEATLREG 129 I + + + + + G +V+ T+ ++ G+ R F QP E LR+ Sbjct: 61 YIGIDSENDEAIDYHSDSYDWKNAAGETLLEVDWTSMTDSGWRTRYWFYQPELEKRLRDL 120 Query: 130 LDRFPSVTTHFGHTLQSFVQHEDGVIA--------TVIKADGSTACIHADYLVGTDGGRS 181 V G T Q E+ I I AD I A Y++G DG S Sbjct: 121 ALTMDFVDIRCGFTAVGLSQDENSAIIHGIVTDTPENIPADAQREDIRAKYVIGADGANS 180 Query: 182 TVRELLNVPMSGSTFKSRWLVIDTENDDDTFWQTRVY--CDAKRPVVDVPGPHHTRRYEI 239 VR L + M+ + WL++D + D + T + CD KRP VPG RR+E Sbjct: 181 FVRNSLGLEMNDLGYFFDWLILDLKPTQDIDYGTDHWQLCDPKRPTTIVPGGPGRRRWEF 240 Query: 240 LIHPHEDAEHAMTPERVTELLRPFRNGRPTDIV-RKVVYTFHARMADKWRENRVFLAGDA 298 + P ED + + E LL P+ I+ R VY F AR A +WR R +AGDA Sbjct: 241 MALPGEDLKELASEESAWNLLEPWDVTPGKAILERSAVYRFQARWAQEWRSGRALIAGDA 300 Query: 299 AHLTPPYAGQGLNSGIRDAHNLGWKLVALHNGILTNLALDSYETERRPHAWSLIKLALNL 358 AHL PP+AG+G+ +G+RD+ L W+L + +G + LD+Y ERR H I +++L Sbjct: 301 AHLMPPFAGEGMCAGLRDSLALAWRLDLVLSGKSDDALLDTYGEERREHVHYYIDFSMDL 360 Query: 359 GFVMAPKTRLHAWIAQTFFTLSAYVPPVRDYFLQMKFKPKPQYANGLLGPDL--TSGMRG 416 G V+ A + +++ Q A+ LGP + G Sbjct: 361 GNVICITDEDEARLRDERM--------IKELEAQDGVPVNTDVAH--LGPGIWDKDSSHG 410 Query: 417 HMFSQPTVLLTDGRETLLDDVIGHRFALISYGSVP--TLKHPLWRTTNAIRIAILPSGSD 474 ++ ++ GR+ DD +G +A++ + P L +AI AI+ S D Sbjct: 411 GELAKQGIVEYQGRKARFDDAVGRGWAVLGLNTDPREVLDEDSLVALDAIG-AIVESVGD 469 Query: 475 AQASEKTDSVIVIDKNDRLRTFFEKNKDHIAFLRPDRYV 513 A ++ V+D + ++ RPD YV Sbjct: 470 ATSA-------VLDVEGLYTRWLKEAGATFIITRPDFYV 501 >STM1546 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Sty Salmonella typhimurium LT2 Length = 502 Score = 126 bits (316), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 119/357 (33%), Positives = 164/357 (45%), Gaps = 28/357 (7%) Query: 18 TAVLVIGAGPTGLTLANILGQGGVRTVVIDRKESTVGEPRAVSIDDESLRTMQAIDLVKD 77 T VL+ GAG TGLTLA L + GV +I+++ + R I + + + Sbjct: 7 TDVLICGAGVTGLTLAIELARHGVSFRLIEKRTTPFIGSRGKGIQPRTQEIFEDLG---- 62 Query: 78 VLKNVVTGYGVHYLTKPGGRCFAKVEPTASEYGYP-RRNAFRQPLF------EATLREGL 130 +L VV G++ + + V+ + + P + PL E +RE L Sbjct: 63 ILNKVVAAGGLYPRLRTYRHDGSYVDSDIAHHTKPTHAEPYHLPLMVPQNVTETIMREQL 122 Query: 131 DRFPSVTTHFGHTLQSFVQHEDGVIATVIKADGSTACIHADYLVGTDGGRSTVRELLNVP 190 + FG L+ F Q V A V G I A YL+G DGG S VR+ L V Sbjct: 123 KAWGH-RVEFGCELRHFAQTPRTVTAYVAGPAGEEVII-AHYLIGADGGGSFVRKKLGVS 180 Query: 191 MSGSTFKSRWLVIDTE----NDDDTFWQTRVYCDAKRPVVDVPGPHHTRRYEILIHPHED 246 G T LV D N D W D R + P T+ ++I D Sbjct: 181 FPGRTLGIHALVADASLSGLNRD--VWHHFNDGDMARMITICPLAG-TQLFQIQALLAPD 237 Query: 247 AEHAMTPERVTELLRPFRNGRPTDIVRKVV-----YTFHARMADKWRENRVFLAGDAAHL 301 + + +T L R GR TD+ + Y +AR+A+ +R +VFLAGDAAH+ Sbjct: 238 DSQNFSADVLTAFLTE-RIGR-TDVRIHSIPWVSKYQMNARIAEHYRVGKVFLAGDAAHV 295 Query: 302 TPPYAGQGLNSGIRDAHNLGWKLVALHNGILTNLALDSYETERRPHAWSLIKLALNL 358 PP GQGLN+ I+DA+NLGWK+ A G L LDSYE ERRP A SL+ L+ L Sbjct: 296 HPPTGGQGLNTSIQDAYNLGWKMAASLRGAGEEL-LDSYEQERRPIAESLLHLSTRL 351