BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0209.p (328 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3366 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeru... 539 e-153 HP0294 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pyl... 516 e-146 jhp0279 [R] COG0388 Predicted amidohydrolase jHp Helicobacter py... 512 e-145 HP1238 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pyl... 219 5e-57 jhp1159 [R] COG0388 Predicted amidohydrolase jHp Helicobacter py... 214 2e-55 >PA3366 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeruginosa Length = 346 Score = 539 bits (1388), Expect = e-153, Method: Compositional matrix adjust. Identities = 246/328 (75%), Positives = 282/328 (85%) Query: 1 VGVAVVNYKMPRLHTRAEVMDNVNRIAAMLIGMKQGLPGLDLVIFPEYSTHGIMYDEKEM 60 VGVAVVNYKMPRLHT AEV+DN +IA M++GMKQGLPG+DLV+FPEYS GIMYD EM Sbjct: 13 VGVAVVNYKMPRLHTAAEVLDNARKIAEMIVGMKQGLPGMDLVVFPEYSLQGIMYDPAEM 72 Query: 61 YDTAASIPGEETRVFSEACRIADVWGVFSLTGERHEEHPHKAPYNTLILINNQGEIVQKY 120 +TA +IPGEET +FS ACR A+VWGVFSLTGERHEEHP KAPYNTL+LI+N GEIVQKY Sbjct: 73 METAVAIPGEETEIFSRACRKANVWGVFSLTGERHEEHPRKAPYNTLVLIDNNGEIVQKY 132 Query: 121 RKIMPWTPIEGWYPGDTTYVCDGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGY 180 RKI+PW PIEGWYPG TYV +GPKG+K+SLIICDDGNYPEIWRDCAMKGAELIVRCQGY Sbjct: 133 RKIIPWCPIEGWYPGGQTYVSEGPKGMKISLIICDDGNYPEIWRDCAMKGAELIVRCQGY 192 Query: 181 MYPAKEQQILVSKAMAWMNNVYVAVANAAGFDGVYSYFGHSAIVGFDGRTLGECETEEMG 240 MYPAK+QQ++++KAMAW NN YVAVANAAGFDGVYSYFGHSAI+GFDGRTLGEC EEMG Sbjct: 193 MYPAKDQQVMMAKAMAWANNCYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEEMG 252 Query: 241 IQYAELSVGAIRDARRNWQSQNHLFKLVHRGYTGKINSGESSAGVADCPFDFYKTWVNDP 300 IQYA+LS+ IRDAR N QSQNHLFK++HRGY+G SG+ G+A+CPF+FY+TWV D Sbjct: 253 IQYAQLSLSQIRDARANDQSQNHLFKILHRGYSGLQASGDGDRGLAECPFEFYRTWVTDA 312 Query: 301 QAARAQVEAITRKTAGTPECPVPGIPNE 328 + AR VE +TR T G +CPV +P E Sbjct: 313 EKARENVERLTRSTTGVAQCPVGRLPYE 340 >HP0294 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pylori 26695 Length = 339 Score = 516 bits (1328), Expect = e-146, Method: Compositional matrix adjust. Identities = 240/328 (73%), Positives = 276/328 (84%), Gaps = 1/328 (0%) Query: 1 VGVAVVNYKMPRLHTRAEVMDNVNRIAAMLIGMKQGLPGLDLVIFPEYSTHGIMYDEKEM 60 VGVAVVNYKMPRLHT+ EV++N IA ++ G+KQGLPGLDL+IFPEYSTHGIMYD +EM Sbjct: 13 VGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEYSTHGIMYDRQEM 72 Query: 61 YDTAASIPGEETRVFSEACRIADVWGVFSLTGERHEEHPHKAPYNTLILINNQGEIVQKY 120 +DTAAS+PGEET +F+EAC+ VWGVFSLTGE+HE+ K PYNTLIL+N++GEIVQKY Sbjct: 73 FDTAASVPGEETAIFAEACKKNKVWGVFSLTGEKHEQ-AKKNPYNTLILVNDKGEIVQKY 131 Query: 121 RKIMPWTPIEGWYPGDTTYVCDGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGY 180 RKI+PW PIE WYPGD TYV DGPKGLKVSLIICDDGNYPEIWRDCAM+GAELIVRCQGY Sbjct: 132 RKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAMRGAELIVRCQGY 191 Query: 181 MYPAKEQQILVSKAMAWMNNVYVAVANAAGFDGVYSYFGHSAIVGFDGRTLGECETEEMG 240 MYPAKEQQI + KAMAW N YVAVANA GFDGVYSYFGHS+I+GFDG TLGEC EE G Sbjct: 192 MYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDGHTLGECGEEENG 251 Query: 241 IQYAELSVGAIRDARRNWQSQNHLFKLVHRGYTGKINSGESSAGVADCPFDFYKTWVNDP 300 +QYA+LSV IRDAR+ QSQN LFKL+HRGY+G SG+ GVA+CPF+FYKTWVNDP Sbjct: 252 LQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAECPFEFYKTWVNDP 311 Query: 301 QAARAQVEAITRKTAGTPECPVPGIPNE 328 + A+ VE ITR + G CPV +P + Sbjct: 312 KKAQENVEKITRPSVGVAACPVGDLPTK 339 >jhp0279 [R] COG0388 Predicted amidohydrolase jHp Helicobacter pylori J99 Length = 339 Score = 512 bits (1318), Expect = e-145, Method: Compositional matrix adjust. Identities = 238/328 (72%), Positives = 274/328 (83%), Gaps = 1/328 (0%) Query: 1 VGVAVVNYKMPRLHTRAEVMDNVNRIAAMLIGMKQGLPGLDLVIFPEYSTHGIMYDEKEM 60 VGVAVVNYKMPRLHT+ EV++N IA ++ G+KQGLPGLDL+IFPEYSTHGIMYD +EM Sbjct: 13 VGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEYSTHGIMYDRQEM 72 Query: 61 YDTAASIPGEETRVFSEACRIADVWGVFSLTGERHEEHPHKAPYNTLILINNQGEIVQKY 120 +DTAAS+PGEET + +EAC+ VWGVFSLTGE+HE+ K PYNTLIL+N++GEIVQKY Sbjct: 73 FDTAASVPGEETAILAEACKKNKVWGVFSLTGEKHEQ-AKKNPYNTLILVNDKGEIVQKY 131 Query: 121 RKIMPWTPIEGWYPGDTTYVCDGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGY 180 RKI+PW PIE WYPGD TYV DGPKGLKVSLIICDDGNYPEIWRDCAM+GAELIVRCQGY Sbjct: 132 RKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAMRGAELIVRCQGY 191 Query: 181 MYPAKEQQILVSKAMAWMNNVYVAVANAAGFDGVYSYFGHSAIVGFDGRTLGECETEEMG 240 MYPAKEQQI + KAMAW N YVAVANA GFDGVYSYFGHS+I+GFDG TLGEC EE G Sbjct: 192 MYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDGHTLGECGEEENG 251 Query: 241 IQYAELSVGAIRDARRNWQSQNHLFKLVHRGYTGKINSGESSAGVADCPFDFYKTWVNDP 300 +QYA+LSV IRDAR+ QSQN LFKL+HRGY+G SG+ GVA+CPF+FYKTWVNDP Sbjct: 252 LQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAECPFEFYKTWVNDP 311 Query: 301 QAARAQVEAITRKTAGTPECPVPGIPNE 328 + A+ VE TR + G CPV +P + Sbjct: 312 KKAQENVEKFTRPSVGVAACPVGDLPTK 339 >HP1238 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pylori 26695 Length = 334 Score = 219 bits (559), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 115/285 (40%), Positives = 170/285 (59%), Gaps = 4/285 (1%) Query: 3 VAVVNYKMPRLHTRAEVMDNVNRIAAMLIGMKQGLPGLDLVIFPEYSTHGIMYDEKEMYD 62 VA + + +P +++R ++ N+ I L K G PG++L+IFPEYST G+ + + Sbjct: 16 VAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEE 75 Query: 63 TAASIPGEETRVFSEACRIADVWGVFSLTGERHEEHPHKAPYNTLILINNQGEIVQKYRK 122 +PG+ET ++++AC+ A V+GVFS+ ER+ + +K PYNT I+I+ QGEI+ KYRK Sbjct: 76 FLLDVPGKETELYAKACKEAKVYGVFSIM-ERNPDS-NKNPYNTAIIIDPQGEIILKYRK 133 Query: 123 IMPWTPIEGWYPGDTTY-VCDGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGYM 181 + PW PIE WYPGD VC+GP G K+++ IC DG PE+ R+ A KG + +R GY Sbjct: 134 LFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYS 193 Query: 182 YPAKEQQILVSKAMAWMNNVYVAVANAAGFDGVYSYFGHSAIVGFDGRTLGECETEEMGI 241 +Q IL +++ AW N +Y N AG+D V+ YFG I FDG TL + I Sbjct: 194 TQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEI 253 Query: 242 QYAELSVGAIRDARRNWQSQNHLFKLVHRGYTGKINSGESSAGVA 286 E+ +AR +W +N+++ L HRGY K GE AG+ Sbjct: 254 VTGEIYPKMADNARLSWGLENNIYNLGHRGYVAK-PGGEHDAGLT 297 >jhp1159 [R] COG0388 Predicted amidohydrolase jHp Helicobacter pylori J99 Length = 334 Score = 214 bits (545), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 112/285 (39%), Positives = 169/285 (59%), Gaps = 4/285 (1%) Query: 3 VAVVNYKMPRLHTRAEVMDNVNRIAAMLIGMKQGLPGLDLVIFPEYSTHGIMYDEKEMYD 62 VA + + +P +++R ++ N+ I L K G PG++L+IFPEYST G+ + + Sbjct: 16 VAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEE 75 Query: 63 TAASIPGEETRVFSEACRIADVWGVFSLTGERHEEHPHKAPYNTLILINNQGEIVQKYRK 122 +PG+ET ++++AC+ A V+GV S+ ER+ + ++ PYNT I+I+ QG+I+ KYRK Sbjct: 76 FLLDVPGKETELYAKACKEAKVYGVLSIM-ERNPDS-NENPYNTAIIIDPQGKIILKYRK 133 Query: 123 IMPWTPIEGWYPGDTTY-VCDGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGYM 181 + PW PIE WYPGD VC+GP G K+++ IC DG PE+ R+ A KG + +R GY Sbjct: 134 LFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYS 193 Query: 182 YPAKEQQILVSKAMAWMNNVYVAVANAAGFDGVYSYFGHSAIVGFDGRTLGECETEEMGI 241 +Q IL +++ AW N +Y N AG+D V+ YFG I FDG TL + I Sbjct: 194 TQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEI 253 Query: 242 QYAELSVGAIRDARRNWQSQNHLFKLVHRGYTGKINSGESSAGVA 286 E+ +AR +W +N+++ L HRGY K GE AG+ Sbjct: 254 VTGEIYPKMADNARLSWGLENNIYNLGHRGYVAK-PGGEHDAGLT 297